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Panama Tours & Cruises Starting In March 2026, 2027 and 2028

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89 Trips (825 Trip Departures)
20 Day Panama Canal & the Americas with Viking Cruises
Cruise

20 Days (19 Nights) Santiago to New York
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Mar 2026 to Apr 2028
Visit: Chile, Peru, Panama, Jamaica, Bahamas
Flights Included
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,995
Suite
$15,995
From
US$11,995
Save 3,000
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 27 March 2028
Visit: USA, Dominican Republic, Aruba, Curacao, Panama, Cayman Islands
Exclusive Savings
Inside
$2,154
Oceanview
$2,354
Balcony
$2,704
Suite
$7,193
From
US$2,154
Save 1,094
Per Person
View Trip
17 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (2)

17 Days (16 Nights) Santiago to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2027 to Mar 2028
Visit: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,259
Oceanview
$2,359
Balcony
$3,259
Suite
$4,986
From
US$2,259
Per Person
View Trip
23 Day Journey To The Amazon with Regent Seven Seas
Cruise

23 Days (22 Nights) Panama City to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 March 2027
Visit: Panama, Aruba, Trinidad and Tobago, Brazil, Grenada, Curacao
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,619
Suite
$17,305
From
US$16,619
Save 23,379
Per Person
View Trip
11 Day Spanish Lullaby with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2028
Visit: Panama, Costa Rica, Honduras, Guatemala, Mexico, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,946
Oceanview
$3,916
Balcony
$4,692
Suite
$6,729
From
US$2,946
Save 3,052
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,670
Suite
$18,220
From
US$12,670
Save 5,430
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departures: Oct 2027 to Apr 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,449
Oceanview
$1,649
Balcony
$2,249
Suite
$3,695
From
US$1,449
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 March 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$2,189
Oceanview
$2,239
Balcony
$4,028
Suite
$8,144
From
US$2,189
Per Person
View Trip
17 Day Miami to LA via Panama Canal with Virgin Voyages
Cruise
 (1)

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Virgin Voyages
Ship: Brilliant Lady
Departures: Mar 2026 to Mar 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
With Love From the World
Up to $300 Onboard Credit
Inside
$1,584
Oceanview
$2,544
Balcony
$3,024
Suite
$9,104
From
US$1,584
Per Person
View Trip
11 Day Palms & Panama Canal with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Tampa to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 25 March 2026
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,450
Oceanview
$2,590
Balcony
-
Suite
-
From
US$2,450
Save 4,548
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 22 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
Flights Included
Inside
-
Oceanview
-
Balcony
$11,995
Suite
$29,995
From
US$11,995
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Feb 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$3,411
Save 1,121
Per Person
View Trip
25 Day Central American Explorer with Explore Worldwide
Tour

25 Days Panama City to Antigua
Operated By: Explore Worldwide
Departures: Feb 2026 to Nov 2026
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama, Guatemala, Honduras, El Salvador, Nicaragua
Exclusive Savings
From
US$4,957
Save 1,063
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Nov 2026 to Mar 2027
Visit: USA, Colombia, Panama, Aruba, Curacao, Bonaire
Exclusive Savings
Inside
$2,259
Oceanview
$2,387
Balcony
$4,256
Suite
$8,272
From
US$2,259
Save 1,314
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sun
Departures: Dec 2026 to Apr 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico
Inside
$1,689
Oceanview
$1,849
Balcony
$2,527
Suite
$3,711
From
US$1,689
Per Person
View Trip
11 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (2)

11 Days (10 Nights) Colon to Fort-de-France
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 12 March 2027
Visit: Panama, Colombia, Bonaire, Saint Vincent, Saint Lucia, Guadeloupe, Martinique
Inside
-
Oceanview
-
Balcony
$6,760
Suite
$10,670
From
US$6,760
Per Person
View Trip
11 Day Panama & Pristine Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$3,046
Oceanview
$3,822
Balcony
$4,404
Suite
$6,344
From
US$3,046
Save 3,152
Per Person
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departures: Jan 2027 to Mar 2027
Visit: USA, Mexico, Belize, Guatemala, Honduras, Costa Rica, Panama
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,775
Balcony
$4,405
Suite
$6,345
From
US$2,999
Save 3,099
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Nov 2026 to Mar 2028
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Bonus Onboard Credit
Inside
$946
Oceanview
$1,066
Balcony
$1,366
Suite
$3,770
From
US$946
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 28 March 2027
Visit: USA, Cayman Islands, Jamaica, Costa Rica, Panama, Aruba, Dominican Republic
Princess Standard
Inside
$949
Oceanview
$1,099
Balcony
$1,349
Suite
$1,749
From
US$949
Per Person
View Trip
20 Day Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Azamara Cruises
Cruise
 (3)

20 Days (19 Nights) Santiago to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 March 2027
Visit: Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Exclusive Savings
Inside
$6,446
Oceanview
$7,231
Balcony
$8,075
Suite
$13,410
From
US$6,446
Save 143
Per Person
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Nov 2027 to Mar 2028
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands, Mexico
Princess Standard
Inside
$1,249
Oceanview
$1,449
Balcony
$1,849
Suite
$2,749
From
US$1,249
Per Person
View Trip
34 Day Sydney To Miami with Cunard
Cruise
 (13)

34 Days (33 Nights) Sydney to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 25 March 2028
Visit: Australia, Tonga, USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$6,927
Oceanview
$8,115
Balcony
$10,095
Suite
$23,856
From
US$6,927
Per Person
View Trip
13 Day Panama Canal Discovery: Costa Rica & Greater Antilles with Holland America
Cruise
 (3)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departures: Oct 2026 to Mar 2027
Visit: USA, Bahamas, Aruba, Colombia, Panama, Costa Rica, Cayman Islands
Fare Saver
Inside
$1,219
Oceanview
$1,419
Balcony
$2,019
Suite
$4,154
From
US$1,219
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 March 2026
Visit: USA, Jamaica, Aruba, Colombia, Panama, Honduras, Bahamas
Bonus Onboard Credit
Inside
$1,092
Oceanview
$1,282
Balcony
$1,522
Suite
$2,826
From
US$1,092
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 01 March 2026
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Bahamas
Inside
$749
Oceanview
$1,039
Balcony
$1,279
Suite
$3,222
From
US$749
Per Person
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 March 2028
Visit: USA, Cayman Islands, Jamaica, Aruba, Curacao, Colombia, Panama
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,949
Oceanview
$3,919
Balcony
$4,695
Suite
$6,732
From
US$2,949
Save 3,049
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 17 March 2026
Visit: USA, Aruba, Curacao, Colombia, Panama, Costa Rica, Cayman Islands
Princess Standard
Inside
$1,128
Oceanview
$1,131
Balcony
-
Suite
-
From
US$1,128
Per Person
View Trip
13 Day Flavors Of Cartagena with Regent Seven Seas
Cruise

13 Days (12 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 02 March 2028
Visit: USA, Cayman Islands, Jamaica, Dominican Republic, Colombia, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,655
Suite
$9,047
From
US$8,655
Save 14,943
Per Person
View Trip
13 Day Southern Caribbean with Panama with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Jan 2028 to Mar 2028
Visit: USA, Aruba, Colombia, Panama, Costa Rica, Cayman Islands, Mexico
Princess Standard
Inside
$1,500
Oceanview
$1,748
Balcony
$1,750
Suite
$3,049
From
US$1,500
Per Person
View Trip
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