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Panama Tours & Cruises Starting In October 2026, 2027, 2028 and 2029

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62 Days
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55 Trips (680 Trip Departures)
17 Day Panama Canal & Historic Coasts Of South America with Seabourn
Cruise

17 Days (16 Nights) Oranjestad to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 02 October 2028
Visit: Aruba, Panama, Ecuador, Peru, Chile
Inside
-
Oceanview
-
Balcony
$10,999
Suite
$14,999
From
US$10,999
Per Person
View Trip
59 Day Ultimate Central America with Intrepid Travel
Tour

59 Days Mexico City to Panama City
Operated By: Intrepid Travel
Departures: Jul 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$8,128
Save 2,199
Per Person
View Trip
21 Day Ultimate Voyage: Caribbean Islands & the Panama Canal with Scenic
New ReleaseCruise

21 Days (20 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 October 2028
Visit: Bahamas, Turks and Caicos Islands, USA, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$20,890
Suite
$32,605
From
US$20,890
Per Person
View Trip
13 Day Costa Rica to Panama: Surf, Treks & Starry Skies with G Adventures
New ReleaseTour

13 Days San Jose to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,124
Save 125
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,699
Oceanview
$1,869
Balcony
$2,869
Suite
$5,239
From
US$1,699
Per Person
View Trip
14 Day Cycle Nicaragua to the Panama Canal with Explore Worldwide
Tour

14 Days Granada to Panama City
Operated By: Explore Worldwide
Departures: Oct 2026 to Nov 2027
Trip Styles: Adventure, Small Group, Cycling
Visit: Costa Rica, Panama, Nicaragua
Exclusive Savings
From
US$4,720
Save 210
Per Person
View Trip
12 Day Voyage of the Tropics: Bahamas, Caribbean & Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Miami to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 October 2028
Visit: USA, Bahamas, Colombia, Panama
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,683
Suite
$17,554
From
US$9,683
Save 2,412
Per Person
View Trip
18 Day Panama: Craters, Coasts & Highland Mountains with G Adventures
New ReleaseTour

18 Days San Jose to Panama City
Operated By: G Adventures
Departures: Aug 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
From
US$2,099
Per Person
View Trip
17 Day Panama Canal - Ocean To Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 10 October 2027
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,499
Oceanview
$1,699
Balcony
$2,199
Suite
$3,199
From
US$1,499
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 04 October 2026
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,459
Oceanview
$2,359
Balcony
$2,349
Suite
$3,549
From
US$1,459
Per Person
View Trip
10 Day Wellness Retreat - Panama City to Valparaiso with Scenic
New ReleaseCruise

10 Days (9 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 26 October 2026
Visit: Panama, Chile
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,210
Suite
$7,370
From
US$5,210
Save 2,635
Per Person
View Trip
27 Day Amazing Central America with Intrepid Travel
Tour

27 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
US$3,516
Save 952
Per Person
View Trip
29 Day Pan Am 100th Anniversary Legendary Voyage with Holland America
Cruise

29 Days (28 Nights) Miami to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 October 2027
Visit: USA, Bahamas, Jamaica, Dominican Republic (+12 more), Puerto Rico, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Curacao, Aruba, Colombia, Panama, Costa Rica, Belize, Mexico
Book Early & Have It All Fare Option
Inside
$4,179
Oceanview
$4,579
Balcony
$7,079
Suite
$8,859
From
US$4,179
Per Person
View Trip
61 Day Bound For Down Under with Oceania Cruises
Cruise

61 Days (60 Nights) Miami to Sydney
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama (+11 more), Costa Rica, Guatemala, Mexico, French Polynesia, Cook Islands, Niue, Tonga, Fiji, Vanuatu, New Caledonia, Australia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$26,399
Suite
$38,599
From
US$26,399
Save 26,399
Per Person
View Trip
12 Day Pristine Islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Bridgetown to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 20 October 2027
Visit: Barbados, Saint Lucia, Saint Vincent, Curacao, Colombia, Panama
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,863
Suite
$12,090
From
US$9,863
Save 2,567
Per Person
View Trip
19 Day Transamerican Treasures with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,099
Suite
$11,499
From
US$7,099
Save 7,099
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Oct 2027 to Oct 2028
Visit: Panama, Colombia, Ecuador, Peru, Chile
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,819
Suite
$16,648
From
US$12,819
Save 2,176
Per Person
View Trip
10 Day Panama and Costa Rica: Crossing the Canal with Aurora Expeditions
New ReleaseCruise

10 Days (9 Nights) Panama City to San Jose
Cruise Line: Aurora Expeditions
Ship: Douglas Mawson
Departure: 20 October 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
$11,795
Balcony
$12,495
Suite
$18,795
From
US$11,795
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$1,749
Oceanview
$1,949
Balcony
$2,299
Suite
$2,499
From
US$1,749
Per Person
View Trip
18 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

18 Days (17 Nights) Los Angeles to Tampa
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 01 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Cayman Islands
Exclusive Savings
Inside
$1,628
Oceanview
$1,937
Balcony
$3,449
Suite
-
From
US$1,628
Save 730
Per Person
View Trip
18 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Bahamas
Inside
$2,359
Oceanview
$3,159
Balcony
$3,909
Suite
$4,509
From
US$2,359
Per Person
View Trip
62 Day Total Central America: Two Months of Wild with G Adventures
New ReleaseTour

62 Days Mexico City to Panama City
Operated By: G Adventures
Departures: Jun 2026 to Jun 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Guatemala, Mexico, Nicaragua, Panama (+4 more), Belize, Honduras, Costa Rica, El Salvador
From
US$6,199
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise From Los Angeles To New York with Norwegian Cruise Line
Cruise

20 Days (19 Nights) Los Angeles to New York
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$1,949
Oceanview
$2,099
Balcony
$2,449
Suite
$2,649
From
US$1,949
Per Person
View Trip
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama
Exclusive Savings
From
US$1,738
Save 374
Per Person
View Trip
24 Day Panama Canal & Pacific COast with Princess
Cruise

24 Days (23 Nights) Vancouver to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 03 October 2027
Visit: Canada, USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$2,468
Oceanview
$3,096
Balcony
$3,398
Suite
$4,715
From
US$2,468
Per Person
View Trip
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