Panama Tours & Cruises Starting In May 2026, 2027 and 2028

Are you planning a tour to Panama in May 2026, 2027 or 2028? Choose from 18 unique cruises, small group tours and adventures with 656 departures operated by Panama's leading tour operators. Easily compare prices, itineraries, inclusions and traveller reviews to find the Panama tour that best matches your travel style, budget and dates.
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6 Days
62 Days
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$147,995pp
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18 Trips (656 Trip Departures)
New ReleaseTour

6 Days Panama City to Panama City
Operated By: G Adventures
Departures: Apr 2026 to Jan 2028
Visit: Panama
Exclusive Savings
From
A$1,131
Save 408
Per Person
View Trip
New ReleaseTour

6 Days Panama City to Panama City
Operated By: Globus
Departures: Apr 2026 to Mar 2027
Trip Styles: Short Break, Scenic
Visit: Panama
Exclusive Savings
From
A$2,473
Save 334
Per Person
View Trip
New ReleaseTour

18 Days San Jose to Panama City
Operated By: G Adventures
Departures: Jun 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Exclusive Savings
From
A$2,581
Save 556
Per Person
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Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Mar 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Costa Rica, Panama
Exclusive Savings
From
A$2,278
Save 822
Per Person
View Trip
New ReleaseTour

13 Days San Jose to Panama City
Operated By: G Adventures
Departures: May 2026 to Jan 2028
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama
Exclusive Savings
From
A$1,657
Save 222
Per Person
View Trip
New ReleaseTour

27 Days San Jose to Medellin
Operated By: G Adventures
Departures: Dec 2026 to Dec 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Costa Rica, Panama, Colombia
Exclusive Savings
From
A$5,977
Save 136
Per Person
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Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Departures: May 2026 to Mar 2028
Visit: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,347
Oceanview
$1,361
Balcony
$1,782
Suite
$2,103
From
A$1,347
Save 1,678
Per Person
View Trip
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Departures: May 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,247
Oceanview
$1,285
Balcony
$1,540
Suite
$1,902
From
A$1,247
Save 1,396
Per Person
View Trip
Cruise
 (1)

8 Days (7 Nights) Tampa to Colon
Cruise Line: Royal Caribbean
Departure: 02 May 2026
Visit: USA, Cayman Islands, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,018
Oceanview
$1,165
Balcony
$1,509
Suite
$2,220
From
A$1,018
Save 178
Per Person
View Trip
Cruise
 (1)

21 Days (20 Nights) Seattle to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 11 May 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$29,988
From
A$29,988
Save 612
Per Person
View Trip
Cruise

15 Days (14 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 03 May 2026
Visit: USA, Mexico, El Salvador, Panama, Colombia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,608
Oceanview
$4,865
Balcony
$9,974
Suite
-
From
A$3,608
Per Person
View Trip
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Departure: 11 May 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
$12,500
Balcony
$15,960
Suite
$31,199
From
A$12,500
Save 229
Per Person
View Trip
Tour

27 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Mar 2026 to Dec 2028
Trip Styles: Adventure, Small Group
Visit: Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
A$5,674
Save 421
Per Person
View Trip
Cruise
 (5)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara Cruises
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Exclusive Savings
Inside
$8,993
Oceanview
$9,708
Balcony
$11,012
Suite
$18,126
From
A$8,993
Save 136
Per Person
View Trip
Tour
 (1)

45 Days Playa del Carmen to Panama City
Operated By: Intrepid Travel
Departures: Apr 2026 to Nov 2028
Trip Styles: Adventure, Coach, Small Group, Scenic
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
A$10,138
Save 752
Per Person
View Trip
New ReleaseTour

62 Days Mexico City to Panama City
Operated By: G Adventures
Departures: May 2026 to Oct 2027
Trip Styles: Adventure, Small Group, 18-30's
Visit: Guatemala, Mexico, Nicaragua, Panama (+4 more), Belize, Honduras, Costa Rica, El Salvador
Exclusive Savings
From
A$7,290
Save 2,009
Per Person
View Trip
Tour

59 Days Mexico City to Panama City
Operated By: Intrepid Travel
Departures: Mar 2026 to Nov 2028
Trip Styles: Adventure, Small Group
Visit: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
From
A$13,911
Save 319
Per Person
View Trip
Cruise
 (5)

36 Days (35 Nights) San Diego to London
Cruise Line: Azamara Cruises
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador (+7 more), Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$16,090
Balcony
$17,481
Suite
$31,770
From
A$16,090
Per Person
View Trip
Results: 18 results

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