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South America Cruises Starting In October 2026, 2027, 2028 and 2029

Are you planning a cruise around South America in October 2026, 2027, 2028 or 2029? Choose from 85 unique expeditions and cruises with 1,137 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the South America cruise that best matches your travel style, budget and dates.
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85 Cruises (1,137 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
From
US$9,664
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$6,994
Save 1,256
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$3,850
Save 1,274
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$9,491
Save 1,634
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$6,596
Save 1,196
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$10,482
Per Person
View Trip
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
Cruise
 (1)

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Nov 2026 to Nov 2028
Visit: Chile, Argentina
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,995
Suite
$14,995
From
US$9,995
Save 1,000
Per Person
View Trip
18 Day Land of the Incas with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

18 Days Lima to Quito
Operated By: Trafalgar
Departures: Oct 2026 to Nov 2026
Visit: Peru, Ecuador
Today's Deal
Exclusive Savings
From
US$9,361
Save 470
Per Person
View Trip
7 Day Galapagos Adventure: Northern Islands (Grand Daphne) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$3,966
Save 1,249
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2026 to Mar 2027
Visit: Argentina, Chile
Flash Sale
Exclusive Savings
From
US$9,799
Save 400
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil or Lima to Quito
Operated By: Tauck
Ships: Silver Origin
Departures: Sep 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
-
Balcony
$16,990
Suite
$29,235
From
US$16,990
Per Person
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Oct 2027 to Nov 2027
Visit: Chile, Argentina
Inside
-
Oceanview
$10,020
Balcony
$10,740
Suite
$23,130
From
US$10,020
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Oct 2027 to Oct 2028
Visit: Panama, Colombia, Ecuador, Peru, Chile
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,819
Suite
$16,648
From
US$12,819
Save 2,176
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador
Exclusive Savings
From
US$3,679
Save 950
Per Person
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$6,112
Save 2,037
Per Person
View Trip
20 Day Spirit of Peru with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

20 Days Lima to Guayaquil
Operated By: APT
Departures: May 2027 to Oct 2028
Visit: Peru, Ecuador, Galapagos
From
US$21,995
Per Person
View Trip
10 Day Galápagos - Central, South & East Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$5,359
Save 1,370
Per Person
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Jul 2026 to Dec 2026
Visit: Ecuador, Galapagos
From
US$5,199
Per Person
View Trip
17 Day Absolute Galapagos (Grand Daphne) with Intrepid Travel
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$12,721
Save 2,204
Per Person
View Trip
7 Day Galápagos Land & Sea - Central & South Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$3,279
Save 850
Per Person
View Trip
10 Day Classic Galapagos: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$6,354
Save 2,041
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$5,865
Save 1,033
Per Person
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$4,623
Save 1,156
Per Person
View Trip
10 Day Classic Galapagos: Central Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$6,036
Save 2,041
Per Person
View Trip
12 Day Wellness Retreat: Barbados to Rio de Janeiro with Scenic
New ReleaseCruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 23 October 2027
Visit: Barbados, Brazil
Inside
-
Oceanview
-
Balcony
$7,595
Suite
$11,005
From
US$7,595
Per Person
View Trip
17 Day Mysteries of the Inca Empire with Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Jan 2027 to Nov 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$7,610
Save 150
Per Person
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Sep 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
Sign Up Savings
Today's Deal
Exclusive Savings
From
US$7,217
Save 258
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$3,519
Save 880
Per Person
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$3,239
Save 810
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operated By: G Adventures
Departures: Jun 2026 to Dec 2027
Visit: Peru, Ecuador, Galapagos
From
US$8,699
Per Person
View Trip
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South & Central America Cruises

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Country Routes

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Cruise Lines Exploring South & Central America

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