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South America Cruises Starting In April 2027, 2028 and 2029

Are you planning a cruise around South America in April 2027, 2028 or 2029? Choose from 53 unique expeditions and cruises with 1,023 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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53 Cruises (1,023 Cruise Departures)
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$9,406
Save 1,922
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,864
Save 2,093
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$12,772
Save 2,627
Per Person
View Trip
15 Day Chilean Fjords – Highlights of Patagonia (Northbound) with HX Expeditions
Cruise
 (2)

15 Days (14 Nights) Buenos Aires to Valparaiso
Cruise Line: HX Expeditions
Ship: MS Roald Amundsen
Departure: 01 April 2027
Visit: Argentina, Chile
Inside
-
Oceanview
$10,508
Balcony
$15,453
Suite
$15,452
From
A$10,508
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visit: Brazil
Exclusive Savings
Inside
$252
Oceanview
$301
Balcony
$380
Suite
$668
From
A$252
Per Person
View Trip
7 Day MSC Grand Voyages with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Drinks Package
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,952
From
A$3,952
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,094
Save 3,830
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary C) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,352
Save 271
Per Person
View Trip
9 Day Island Hopping in the Galapagos with Exodus Tours
New ReleaseCruise

9 Days (8 Nights) Quito to Quito
Operated By: Exodus Tours
Departures: Oct 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,935
Save 672
Per Person
View Trip
8 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Galapagos
Exclusive Savings
From
A$7,374
Save 3,501
Per Person
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,048
Save 1,434
Per Person
View Trip
9 Day Galápagos Islands – In Darwin’s Footsteps (Eastern Route) with HX Expeditions
Cruise

9 Days (8 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Jul 2026 to Mar 2028
Visit: Ecuador, Galapagos
Inside
-
Oceanview
$10,357
Balcony
-
Suite
$13,556
From
A$10,357
Per Person
View Trip
10 Day Classic Galapagos: Central Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,985
Save 3,522
Per Person
View Trip
7 Day Galapagos Adventure: Northern Islands (Grand Daphne) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,001
Save 2,156
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Quito or Lima to Guayaquil
Operated By: Tauck
Ships: Silver Origin
Departures: Oct 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
Complimentary Hotel Night
From
A$27,290
Per Person
View Trip
10 Day Classic Galapagos: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,136
Save 2,973
Per Person
View Trip
10 Day Galápagos - North, West & Central Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,341
Save 2,350
Per Person
View Trip
15 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

15 Days Lima to Quito
Operated By: Collette
Departures: Aug 2026 to May 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$15,046
Save 603
Per Person
View Trip
10 Day Galápagos - East, Central, & West Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,196
Save 2,084
Per Person
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,094
Save 3,830
Per Person
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Oct 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
Complimentary Hotel Night
From
A$22,390
Per Person
View Trip
17 Day Absolute Galapagos (Grand Daphne) with Intrepid Travel
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$17,104
Save 3,539
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary B) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,352
Save 271
Per Person
View Trip
26 Day Best of South America with Galápagos Cruise with APT
New ReleaseTour + Cruise

26 Days Rio de Janeiro to Guayaquil
Operated By: APT
Departures: Apr 2027 to Nov 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$33,435
Save 2,118
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador
Exclusive Savings
From
A$5,021
Save 2,298
Per Person
View Trip
6 Day Galapagos at a Glance: Southern Islands (Grand Daphne) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,921
Save 977
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Drinks Package
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,697
From
A$2,697
Per Person
View Trip
16 Day Galápagos Islands - Nine of the Best Isles plus Machu Picchu with HX Expeditions
Cruise

16 Days (15 Nights) Lima to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Aug 2026 to Mar 2028
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
$19,911
Balcony
-
Suite
$25,523
From
A$19,911
Per Person
View Trip
6 Day Galapagos Encounter: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,031
Save 1,705
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Sep 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,371
Save 915
Per Person
View Trip
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