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South America Cruises Starting In April 2027, 2028 and 2029

Are you planning a cruise around South America in April 2027, 2028 or 2029? Choose from 57 unique expeditions and cruises with 1,137 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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57 Cruises (1,137 Departures)
57 Cruises (1,137 Departures)
Departures
Duration
2 Days
48 Days
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Price
$200pp
$138,275pp
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7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Dec 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$7,014
Save 314
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,162
Save 2,162
Per Person
View Trip
15 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with Globus
New ReleaseTour + Cruise
 (1)

15 Days Lima to Guayaquil
Operator: Globus
Departures: Jun 2027 to Nov 2028
Interests: Coach, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,725
Save 623
Per Person
View Trip
22 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Nazca Lines & the Amazon with Globus
New ReleaseTour + Cruise
 (1)

22 Days Lima to Quito
Operator: Globus
Departures: Feb 2028 to Nov 2028
Interests: Coach, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$20,807
Save 598
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Jan 2027 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$15,338
Save 493
Per Person
View Trip
15 Day Chilean Fjords – Highlights of Patagonia (Northbound) with HX Expeditions
Cruise
 (2)

15 Days (14 Nights) Buenos Aires to Valparaiso
Operator: HX Expeditions
Ship: MS Roald Amundsen
Departure: 01 April 2027
Visits: Argentina, Chile
Exclusive Savings
Oceanview
$9,348
Balcony
$10,884
Suite
$12,451
From (Per Person)
A$9,348
Save 257
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Maceio
Operator: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,507
From (Per Person)
A$2,507
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Feb 2027 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$762
Oceanview
$782
Balcony
$852
Suite
$1,198
From (Per Person)
A$762
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia +2 more, MSC Musica, MSC Seaview
Departures: Nov 2026 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$607
Balcony
$676
Suite
$1,023
From (Per Person)
A$607
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$391
Suite
$649
From (Per Person)
A$253
Per Person
View Trip
10 Day Galápagos - East, Central, & West Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$6,791
Save 2,448
Per Person
View Trip
10 Day Galápagos - North, West & Central Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,407
Save 222
Per Person
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Quito
Operator: Silversea
Ship: Silver Origin
Departures: Nov 2026 to Mar 2029
Visits: Ecuador, Galapagos
Exclusive Savings
Balcony
$17,118
Suite
$20,366
From (Per Person)
A$17,118
Save 7,685
Per Person
View Trip
10 Day Galápagos - Central, South & East Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Jan 2027 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,498
Save 2,341
Per Person
View Trip
7 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operator: Globus
Departures: Nov 2026 to Mar 2028
Interests: Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,450
Save 276
Per Person
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operator: Globus
Departures: May 2027 to Nov 2028
Interests: Coach, Cruise, Island Hopping, Wildlife
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$24,619
Save 654
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$6,722
Save 147
Per Person
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,369
Save 3,830
Per Person
View Trip
26 Day South American Discovery with Santiago Stopover & Galápagos Cruise with Globus
Tour + Cruise

26 Days Santiago to Guayaquil
Operator: Globus
Departures: May 2027 to Nov 2028
Interests: Coach, Cruise, Island Hopping, Wildlife
Visits: Chile, Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$23,375
Save 616
Per Person
View Trip
8 Day Galápagos - South & East Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$4,815
Save 2,204
Per Person
View Trip
9 Day Galápagos Islands – In Darwin’s Footsteps (Eastern Route) with HX Expeditions
Cruise

9 Days (8 Nights) Quito to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Dec 2026 to Mar 2029
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$11,804
Suite
$15,060
From (Per Person)
A$11,804
Save 325
Per Person
View Trip
10 Day Classic Galapagos: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$11,144
Save 407
Per Person
View Trip
18 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galápagos with the Nazca Lines with Globus
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operator: Globus
Departures: Feb 2028 to Nov 2028
Interests: Coach, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,520
Save 465
Per Person
View Trip
17 Day Complete Galápagos - Eden with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operator: G Adventures
Departures: Jan 2027 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$12,303
Save 4,436
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operator: G Adventures
Departures: Feb 2027 to Dec 2027
Interests: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,111
Save 279
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary C) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operator: Exodus
Departures: Nov 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,686
Save 281
Per Person
View Trip
6 Day Galapagos Encounter: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operator: Intrepid
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,754
Save 1,483
Per Person
View Trip
8 Day Galapagos Outer Loop Itinerary with Celebrity Cruises
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: Celebrity Cruises
Ship: Celebrity Flora
Departures: Dec 2026 to Dec 2028
Visits: Galapagos
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$13,594
From (Per Person)
A$13,594
Save 7,913
Per Person
View Trip
8 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: G Adventures
Departures: Dec 2026 to Dec 2028
Visits: Galapagos
Exclusive Savings
From (Per Person)
A$9,287
Save 1,979
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary B) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operator: Exodus
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,895
Save 294
Per Person
View Trip
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South & Central America Cruises

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Travel Styles

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Countries

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Cities

Cruises from Baltra Island Cruises from Buenos Aires Cruises from Lima Cruises from Manaus Cruises from Quito Cruises from Rio de Janeiro Cruises from Santiago Cruises from Santos Cruises from Sao Paulo

Routes

Cruises from Baltra Island to Baltra Island Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Santiago Cruises from Itajai to Itajai Cruises from Lima to Guayaquil Cruises from Lima to Quito Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Ecuador Cruises from USA to England Cruises from Dominican Republic to USA Cruises from Chile to USA Cruises from Panama to USA Cruises from Brazil to USA Cruises from Argentina to USA Cruises from USA to Holland Cruises from USA to Chile Cruises from Argentina to Chile Cruises from Brazil to Spain Cruises from USA to Spain Cruises from USA to Brazil Cruises from Argentina to Brazil Cruises from USA to Canada Cruises from Brazil to Ecuador

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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