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Central America Cruises Starting In March 2027 and 2028

Are you planning a cruise to Central America in March 2027 or 2028? Choose from 42 unique cruises and 265 departures operated by Central America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Central America cruise that best matches your travel style, budget and dates.
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42 Cruises (265 Cruise Departures)
11 Day Spanish Lullaby with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2028
Visit: Panama, Costa Rica, Honduras, Guatemala, Mexico, USA
Your World Included Credit
Exclusive Savings
Inside
$5,855
Oceanview
$7,795
Balcony
$9,347
Suite
$13,421
From
US$5,855
Save 143
Per Person
View Trip
17 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

17 Days (16 Nights) Santiago to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 March 2027
Visit: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Inside
$2,359
Oceanview
$2,459
Balcony
$3,259
Suite
$4,986
From
US$2,359
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departures: Oct 2027 to Apr 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,399
Oceanview
$1,599
Balcony
$2,199
Suite
$3,636
From
US$1,399
Per Person
View Trip
8 Day Western Caribbean From New Orleans To New Orleans with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) New Orleans to New Orleans
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Breakaway, Norwegian Escape, Norwegian Getaway
Departures: Mar 2026 to Apr 2028
Visit: USA, Mexico, Honduras, Belize
Inside
$619
Oceanview
$669
Balcony
$769
Suite
$899
From
US$619
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Dec 2026 to Mar 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$9,460
Suite
$14,480
From
US$9,460
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 18 March 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,479
Oceanview
$1,699
Balcony
$2,099
Suite
$3,049
From
US$1,479
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas
Departures: Mar 2026 to Oct 2026
Visit: USA, Mexico, Belize, Honduras
Exclusive Savings
Inside
$562
Oceanview
$672
Balcony
$1,134
Suite
$1,201
From
US$562
Save 553
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,497
Oceanview
$1,563
Balcony
$1,657
Suite
$2,247
From
US$1,497
Per Person
View Trip
17 Day Panama Canal: Miami to Los Angeles with Virgin Voyages
Cruise
 (1)

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Virgin Voyages
Ship: Brilliant Lady
Departures: Mar 2026 to Mar 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Limited Time Offer
Inside
$1,584
Oceanview
$2,544
Balcony
$3,024
Suite
$9,104
From
US$1,584
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Mar 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$5,300
Suite
$8,950
From
US$5,300
Per Person
View Trip
8 Day Western Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas (+2 more), Radiance of the Seas, Rhapsody of the Seas
Departures: Mar 2026 to Apr 2027
Visit: USA, Mexico, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$516
Oceanview
$573
Balcony
$784
Suite
$1,205
From
US$516
Save 586
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Nov 2026 to Mar 2027
Visit: USA, Colombia, Panama, Aruba, Curacao, Bonaire
Exclusive Savings
Inside
$2,354
Oceanview
$2,850
Balcony
$5,483
Suite
$10,330
From
US$2,619
Save 1,336
Per Person
View Trip
8 Day Perfect Day Cococay & West Carib with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Icon Of The Seas
Departures: Mar 2026 to Jul 2027
Visit: USA, Mexico, Honduras, Bahamas
Bonus Onboard Credit
Exclusive Savings
Inside
$1,260
Oceanview
$1,360
Balcony
$1,423
Suite
$2,622
From
US$1,317
Save 1,277
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 18 March 2028
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,650
Oceanview
$1,869
Balcony
$3,109
Suite
$3,695
From
US$1,650
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 March 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$1,989
Oceanview
$2,039
Balcony
$3,930
Suite
$8,144
From
US$1,989
Per Person
View Trip
8 Day Harvest Caye, Cozumel & Roatan with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Aura, Norwegian Luna
Departures: Nov 2026 to Mar 2028
Visit: USA, Honduras, Belize, Mexico
Exclusive Savings
Inside
$1,049
Oceanview
$1,169
Balcony
$1,299
Suite
$1,945
From
US$1,049
Save 57
Per Person
View Trip
11 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (2)

11 Days (10 Nights) Colon to Fort-de-France
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 12 March 2027
Visit: Panama, Colombia, Bonaire, Saint Vincent, Saint Lucia, Guadeloupe, Martinique
Inside
-
Oceanview
-
Balcony
$6,760
Suite
$11,330
From
US$6,760
Per Person
View Trip
21 Day Panama Canal Connoisseur with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Tampa to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 25 March 2026
Visit: USA, Mexico, Belize, Honduras (+7 more), Costa Rica, Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands
Your World Included Credit
Exclusive Savings
Inside
$12,980
Oceanview
$13,756
Balcony
-
Suite
-
From
US$12,980
Save 318
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 05 March 2028
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Aruba, Curacao, Dominican Republic, Cayman Islands
Inside
$2,149
Oceanview
-
Balcony
$2,851
Suite
-
From
US$2,149
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Feb 2027 to Mar 2027
Visit: USA, Curacao, Bonaire, Aruba (+7 more), Dominican Republic, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Inside
$2,209
Oceanview
$2,396
Balcony
$3,075
Suite
-
From
US$2,209
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Feb 2027 to Mar 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Curacao, Bonaire, Aruba, Dominican Republic
Inside
$2,239
Oceanview
$2,425
Balcony
$2,910
Suite
$11,931
From
US$2,239
Per Person
View Trip
21 Day Panama Canal Navigator with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 March 2027
Visit: USA, Mexico, Belize, Guatemala (+8 more), Honduras, Costa Rica, Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas
Your World Included Credit
Exclusive Savings
Inside
$12,107
Oceanview
$15,017
Balcony
$17,345
Suite
$24,038
From
US$12,107
Save 291
Per Person
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departures: Jan 2027 to Mar 2027
Visit: USA, Mexico, Belize, Guatemala, Honduras, Costa Rica, Panama
Your World Included Credit
Exclusive Savings
Inside
$5,859
Oceanview
$7,799
Balcony
$9,254
Suite
$12,649
From
US$5,859
Save 142
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 March 2026
Visit: USA, Jamaica, Aruba, Colombia, Panama, Honduras, Bahamas
Inside
$829
Oceanview
$1,019
Balcony
$1,259
Suite
$2,826
From
US$829
Per Person
View Trip
30 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

30 Days (29 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 March 2027
Visit: USA, Jamaica, Colombia, Panama (+4 more), Costa Rica, Honduras, Belize, Mexico
Exclusive Savings
Inside
$2,913
Oceanview
$3,505
Balcony
$4,485
Suite
-
From
US$2,913
Save 66
Per Person
View Trip
11 Day Panama & Pristine Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas, USA
Your World Included Credit
Exclusive Savings
Inside
$6,052
Oceanview
$7,992
Balcony
$8,962
Suite
$12,648
From
US$6,052
Save 146
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Nov 2026 to Mar 2028
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Exclusive Savings
Inside
$943
Oceanview
$1,063
Balcony
$1,363
Suite
$3,767
From
US$943
Save 54
Per Person
View Trip
21 Day Treasures Of The Tropics with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 March 2028
Visit: USA, Cayman Islands, Jamaica, Aruba (+7 more), Curacao, Colombia, Panama, Costa Rica, Honduras, Guatemala, Mexico
Your World Included Credit
Exclusive Savings
Inside
$11,133
Oceanview
$14,819
Balcony
$17,826
Suite
$25,586
From
US$11,133
Save 265
Per Person
View Trip
11 Day Palms & Panama Canal with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Tampa to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 25 March 2026
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Your World Included Credit
Exclusive Savings
Inside
$6,733
Oceanview
$7,218
Balcony
-
Suite
-
From
US$6,733
Save 165
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Symphony of the Seas
Departures: Nov 2026 to Aug 2027
Visit: USA, Mexico, Honduras
Bonus Onboard Credit
Exclusive Savings
Inside
$657
Oceanview
$749
Balcony
$871
Suite
$1,782
From
US$657
Save 711
Per Person
View Trip
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