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Central America Cruises Starting In April 2027, 2028 and 2029

Are you planning a cruise to Central America in April 2027, 2028 or 2029? Choose from 40 unique cruises and 173 departures operated by Central America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the Central America cruise that best matches your travel style, budget and dates.
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40 Cruises (173 Cruise Departures)
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2028
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$3,032
Oceanview
$3,319
Balcony
$4,230
Suite
$13,497
From
A$3,032
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departures: Oct 2027 to Apr 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Exclusive Savings
Inside
$2,091
Oceanview
$2,646
Balcony
$3,561
Suite
$5,754
From
A$2,091
Per Person
View Trip
8 Day Western Caribbean From New Orleans To New Orleans with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) New Orleans to New Orleans
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Breakaway, Norwegian Getaway
Departures: Nov 2026 to Apr 2028
Visit: USA, Mexico, Honduras, Belize
Just Cruise Fare
Exclusive Savings
Inside
$1,364
Oceanview
$1,439
Balcony
$1,766
Suite
$1,871
From
A$1,364
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico
Exclusive Savings
Inside
$2,636
Oceanview
$3,290
Balcony
$4,151
Suite
-
From
A$2,636
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Exclusive Savings
Inside
$2,141
Oceanview
$2,313
Balcony
$2,701
Suite
$3,972
From
A$2,141
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visit: Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,790
Suite
$16,716
From
A$9,790
Save 484
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise
 (13)

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$4,261
Oceanview
$5,053
Balcony
$6,488
Suite
-
From
A$4,261
Per Person
View Trip
16 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Tampa to Los Angeles
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 April 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$5,056
Oceanview
$5,615
Balcony
$9,780
Suite
$11,865
From
A$5,056
Save 3,093
Per Person
View Trip
8 Day Western Caribbean Holiday Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Radiance of the Seas
Departures: Nov 2026 to Apr 2027
Visit: USA, Mexico, Honduras, Belize
Exclusive Savings
Inside
$951
Oceanview
$993
Balcony
$1,330
Suite
$2,255
From
A$951
Save 639
Per Person
View Trip
12 Day Costa Rica & the Panama Canal with Aurora Expeditions
New ReleaseCruise

12 Days (11 Nights) San Jose to Panama City
Cruise Line: Aurora Expeditions
Ship: Sylvia Earle
Departure: 09 April 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$24,695
Suite
$36,195
From
A$24,695
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Just Cruise Fare
Exclusive Savings
Inside
$4,455
Oceanview
$5,646
Balcony
$6,987
Suite
$7,880
From
A$4,455
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) New York to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visit: USA, Dominican Republic, Colombia, Panama (+4 more), Costa Rica, Guatemala, Mexico, Canada
Just Cruise Fare
Exclusive Savings
Inside
$4,751
Oceanview
$5,942
Balcony
$7,283
Suite
$8,176
From
A$4,751
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 03 April 2027
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,259
Oceanview
$3,179
Balcony
$4,367
Suite
$8,288
From
A$2,259
Per Person
View Trip
8 Day Perfect Day Cococay & West Caribbean with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Icon Of The Seas
Departures: Jul 2026 to Jul 2027
Visit: USA, Mexico, Honduras, Bahamas
Exclusive Savings
Inside
$1,726
Oceanview
$2,052
Balcony
$2,108
Suite
$3,486
From
A$1,726
Save 1,700
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 01 April 2028
Visit: USA, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Exclusive Savings
Inside
$4,450
Oceanview
$5,064
Balcony
$7,054
Suite
$11,044
From
A$4,450
Per Person
View Trip
19 Day An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders with Explora Journeys
Cruise

19 Days (18 Nights) Panama City to Vancouver
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA, Canada
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$17,679
From
A$17,679
Save 361
Per Person
View Trip
23 Day Panama Canal with Holland America
Cruise

23 Days (22 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 01 April 2028
Visit: USA, Colombia, Panama, Costa Rica (+4 more), El Salvador, Guatemala, Mexico, Canada
Fare Saver
Exclusive Savings
Inside
$5,309
Oceanview
$5,844
Balcony
$8,071
Suite
$12,061
From
A$5,309
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (3)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Exclusive Savings
Inside
$3,168
Oceanview
$3,258
Balcony
$5,158
Suite
$9,297
From
A$3,168
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica (+4 more), El Salvador, Guatemala, Mexico, Canada
Fare Saver
Exclusive Savings
Inside
$3,665
Oceanview
$3,813
Balcony
$5,892
Suite
$10,050
From
A$3,665
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Miami To Los Angeles with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departures: Apr 2027 to Apr 2028
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Just Cruise Fare
Exclusive Savings
Inside
$3,537
Oceanview
$4,237
Balcony
$4,684
Suite
$5,056
From
A$3,537
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ships: Emerald Princess, Island Princess, Sapphire Princess
Departures: Nov 2026 to Apr 2028
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Exclusive Savings
Inside
$2,091
Oceanview
$2,368
Balcony
$2,914
Suite
$3,972
From
A$2,091
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Oosterdam
Departure: 07 April 2028
Visit: USA, Aruba, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,374
Suite
$47,334
From
A$8,374
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

26 Days (25 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico, Canada
Exclusive Savings
Inside
-
Oceanview
$4,916
Balcony
$6,074
Suite
-
From
A$4,916
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Oosterdam
Departure: 07 April 2028
Visit: USA, Aruba, Panama, Costa Rica, Guatemala, Mexico
Fare Saver
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,007
Suite
-
From
A$7,007
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) New York to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 09 April 2027
Visit: USA, Dominican Republic, Colombia, Panama (+4 more), Costa Rica, Guatemala, Mexico, Canada
Just Cruise Fare
Exclusive Savings
Inside
$4,795
Oceanview
$5,345
Balcony
$6,119
Suite
$7,474
From
A$4,795
Per Person
View Trip
12 Day A Journey Of Mayan Discovery & Mexican Exploration with Explora Journeys
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,858
From
A$10,858
Save 222
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Costa Rica, Guatemala, Mexico
Fare Saver
Exclusive Savings
Inside
$2,628
Oceanview
$2,707
Balcony
$4,469
Suite
$8,449
From
A$2,628
Per Person
View Trip
27 Day Los Angeles To Southampton with Cunard
Cruise
 (13)

27 Days (26 Nights) Los Angeles to London
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba, Portugal, England
Exclusive Savings
Inside
$7,037
Oceanview
$8,324
Balcony
$10,700
Suite
$23,570
From
A$7,037
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sun
Departure: 05 April 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico
Just Cruise Fare
Exclusive Savings
Inside
$3,452
Oceanview
$3,704
Balcony
$5,506
Suite
$7,382
From
A$3,452
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Exclusive Savings
Inside
$3,665
Oceanview
$3,813
Balcony
$5,892
Suite
$10,050
From
A$3,665
Per Person
View Trip
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