Home > Cruises > Central America Cruises > April

Central America Cruises Starting In April 2027, 2028 and 2029

Are you planning a cruise to Central America in April 2027, 2028 or 2029? Choose from 37 unique cruises and 183 departures operated by Central America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Central America cruise that best matches your travel style, budget and dates.
Filter Results
Departures
Duration
8 Days
46 Days
Regions
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$400pp
$236,198pp
Countries
Show More...
Filter Results
37 Cruises (183 Cruise Departures)
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departures: Oct 2027 to Apr 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,399
Oceanview
$1,639
Balcony
$2,159
Suite
$3,709
From
US$1,399
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico
Inside
$1,564
Oceanview
$2,008
Balcony
$2,625
Suite
$10,042
From
US$1,564
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$6,040
Suite
$9,440
From
US$6,040
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Sep 2026 to Apr 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,457
Oceanview
$1,610
Balcony
$1,610
Suite
$1,810
From
US$1,457
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise
 (13)

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Inside
$3,119
Oceanview
$3,619
Balcony
$4,309
Suite
$11,009
From
US$3,119
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2028
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Inside
$1,757
Oceanview
$2,127
Balcony
$3,297
Suite
$15,177
From
US$1,757
Per Person
View Trip
8 Day Western Caribbean From New Orleans To New Orleans with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) New Orleans to New Orleans
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Breakaway, Norwegian Escape, Norwegian Getaway
Departures: May 2026 to Apr 2028
Visit: USA, Mexico, Honduras, Belize
Inside
$619
Oceanview
$659
Balcony
$1,029
Suite
$1,059
From
US$619
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) New York to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visit: USA, Dominican Republic, Colombia, Panama (+4 more), Costa Rica, Guatemala, Mexico, Canada
Inside
$2,539
Oceanview
$3,339
Balcony
$4,239
Suite
$4,839
From
US$2,539
Per Person
View Trip
8 Day Western Caribbean Holiday Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Radiance of the Seas
Departures: Nov 2026 to Apr 2027
Visit: USA, Mexico, Honduras, Belize
Bonus Onboard Credit
Exclusive Savings
Inside
$501
Oceanview
$575
Balcony
$717
Suite
$1,363
From
US$501
Save 510
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 03 April 2027
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Sanctuary Collection
Inside
$1,429
Oceanview
$2,159
Balcony
$2,909
Suite
$5,679
From
US$1,429
Per Person
View Trip
8 Day Perfect Day Cococay & West Caribbean with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Icon Of The Seas
Departures: May 2026 to Jul 2027
Visit: USA, Mexico, Honduras, Bahamas
Bonus Onboard Credit
Exclusive Savings
Inside
$1,189
Oceanview
$1,519
Balcony
$1,562
Suite
$2,386
From
US$1,189
Save 1,204
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 01 April 2028
Visit: USA, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Book Early & Have It All Fare Option
Inside
$2,864
Oceanview
$3,264
Balcony
$4,564
Suite
$7,164
From
US$2,864
Per Person
View Trip
16 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Tampa to Los Angeles
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 18 April 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$3,770
Oceanview
$3,987
Balcony
$7,088
Suite
-
From
US$4,440
Save 1,390
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 14 April 2028
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$2,429
Oceanview
$3,229
Balcony
$4,129
Suite
$4,729
From
US$2,429
Per Person
View Trip
23 Day Panama Canal with Holland America
Cruise

23 Days (22 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 01 April 2028
Visit: USA, Colombia, Panama, Costa Rica (+4 more), El Salvador, Guatemala, Mexico, Canada
Book Early & Have It All Fare Option
Inside
$3,409
Oceanview
$3,759
Balcony
$5,209
Suite
$7,809
From
US$3,409
Per Person
View Trip
19 Day An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders with Explora Journeys
Cruise

19 Days (18 Nights) Panama City to Vancouver
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA, Canada
Inside
-
Oceanview
-
Balcony
-
Suite
$12,480
From
US$12,480
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (3)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$1,924
Oceanview
$1,984
Balcony
$3,264
Suite
$6,204
From
US$1,924
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (9)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ships: Crown Princess, Emerald Princess (+2 more), Island Princess, Sapphire Princess
Departures: Nov 2026 to Apr 2028
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,327
Oceanview
$1,559
Balcony
$2,149
Suite
$3,257
From
US$1,327
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise
 (3)

22 Days (21 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica (+4 more), El Salvador, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,249
Oceanview
$2,349
Balcony
$3,749
Suite
$6,699
From
US$2,249
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

26 Days (25 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico, Canada
Inside
-
Oceanview
$3,063
Balcony
$3,905
Suite
-
From
US$3,063
Per Person
View Trip
16 Day Panama Canal Repositioning Cruise From Miami To Los Angeles with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departures: Apr 2027 to Apr 2028
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$1,809
Oceanview
$2,309
Balcony
$2,599
Suite
$2,829
From
US$1,809
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$1,724
Oceanview
$1,774
Balcony
$2,964
Suite
$5,644
From
US$1,724
Per Person
View Trip
12 Day A Journey Of Mayan Discovery & Mexican Exploration with Explora Journeys
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA
Inside
-
Oceanview
-
Balcony
-
Suite
$6,915
From
US$6,915
Per Person
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) New York to Seattle
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 09 April 2027
Visit: USA, Dominican Republic, Colombia, Panama (+4 more), Costa Rica, Guatemala, Mexico, Canada
Inside
$2,559
Oceanview
$2,959
Balcony
$3,959
Suite
$4,459
From
US$2,559
Per Person
View Trip
27 Day Los Angeles To Southampton with Cunard
Cruise
 (13)

27 Days (26 Nights) Los Angeles to London
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba, Portugal, England
Inside
$4,879
Oceanview
$5,679
Balcony
$7,179
Suite
$16,879
From
US$4,879
Per Person
View Trip
12 Day Panama Canal From Miami To Miami with Norwegian Cruise Line
Cruise
 (1)

12 Days (11 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sun
Departure: 05 April 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico
Inside
$1,859
Oceanview
$2,159
Balcony
$3,459
Suite
$4,699
From
US$1,859
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Orlando to Los Angeles
Cruise Line: Princess
Ship: Star Princess
Departure: 07 April 2028
Visit: USA, Turks and Caicos Islands, Aruba, Panama, Mexico
Princess Standard
Sanctuary Collection
Inside
$1,999
Oceanview
$2,299
Balcony
$2,799
Suite
$3,749
From
US$1,999
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico, Canada
Fare Saver
Inside
$2,399
Oceanview
$2,499
Balcony
$3,899
Suite
$6,699
From
US$2,399
Per Person
View Trip
12 Day Pristine islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 April 2027
Visit: Panama, Colombia, Curacao, Saint Vincent, Saint Lucia, Barbados
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,891
Suite
$12,118
From
US$9,891
Save 2,539
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

20 Days (19 Nights) New York to San Francisco
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 09 April 2027
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Inside
$2,439
Oceanview
$2,839
Balcony
$3,839
Suite
$4,339
From
US$2,439
Per Person
View Trip
Results: 1-30 of 37

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

Festivals & Events Luxury Cruises

Countries

Bahamas Belize Colombia Costa Rica Honduras Mexico Panama USA

Cities

Cruises from Fort Lauderdale Cruises from Galveston Cruises from Los Angeles Cruises from Miami Cruises from New Orleans Cruises from New York Cruises from Orlando Cruises from Panama City Cruises from Santiago Cruises from Tampa

Routes

Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Fort Lauderdale to Vancouver Cruises from Galveston to Galveston Cruises from Los Angeles to Miami Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Miami to Los Angeles Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Miami Cruises from Miami to London Cruises from New Orleans to New Orleans Cruises from New York to New York Cruises from New York to London Cruises from Tampa to Tampa

Country Routes

Cruises from Chile to USA Cruises from Dominican Republic to USA Cruises from Peru to USA Cruises from Australia to USA Cruises from Panama to USA Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to Chile Cruises from USA to England Cruises from USA to Panama

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations