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South America Cruises Starting In March 2027, 2028 and 2029

Are you planning a cruise around South America in March 2027, 2028 or 2029? Choose from 130 unique expeditions and cruises with 1,607 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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130 Cruises (1,607 Departures)
130 Cruises (1,607 Departures)
Departures
Duration
2 Days
63 Days
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Price
$200pp
$173,595pp
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7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$6,708
Save 314
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,152
Save 2,797
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,823
Save 493
Per Person
View Trip
2 Day South America with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Itajai to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$335
Balcony
$414
Suite
$489
From (Per Person)
A$335
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,263
Suite
$3,061
From (Per Person)
A$1,263
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visits: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,327
Oceanview
$4,624
Balcony
$5,614
Suite
$8,039
From (Per Person)
A$4,327
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$401
Suite
$669
From (Per Person)
A$253
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Operator: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
$786
Oceanview
$954
Balcony
$1,182
Suite
$1,489
From (Per Person)
A$786
Per Person
View Trip
9 Day Chile & Peru Cruise: Arica, Pisco & Lima with Azamara Cruises
Cruise
 (6)

9 Days (8 Nights) Santiago to Lima
Operator: Azamara
Ship: Azamara Journey
Departure: 10 March 2027
Visits: Chile, Peru
Azamara Always Included
Exclusive Savings
Inside
$2,972
Oceanview
$2,815
Balcony
$3,403
Suite
-
From (Per Person)
A$2,815
Save 44
Per Person
View Trip
3 Day South America with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Paranagua to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 13 March 2027
Visits: Brazil
Exclusive Savings
Inside
$402
Oceanview
-
Balcony
$540
Suite
$730
From (Per Person)
A$402
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,792
Oceanview
$4,188
Balcony
$5,920
Suite
$7,900
From (Per Person)
A$3,792
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,716
Suite
$2,362
From (Per Person)
A$1,280
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Rio de Janeiro to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,176
Suite
$2,919
From (Per Person)
A$1,176
Per Person
View Trip
18 Day South Georgia & Falklands - From Punta Arenas to Montevideo  with HX Expeditions
Cruise
 (1)

18 Days (17 Nights) Santiago to Montevideo
Operator: HX Expeditions
Ship: MS Fram
Departure: 12 March 2027
Visits: Chile, Argentina, Falkland Islands, South Georgia Island, Uruguay
Exclusive Savings
Inside
-
Oceanview
$16,051
Suite
$20,290
From (Per Person)
A$16,051
Save 325
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,119
Suite
$1,836
From (Per Person)
A$852
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Feb 2027 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$802
Oceanview
$951
Balcony
$1,149
Suite
$1,455
From (Per Person)
A$802
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Maceio
Operator: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,315
Suite
-
From (Per Person)
A$1,315
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 07 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,080
Suite
$3,959
From (Per Person)
A$2,080
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise
 (1)

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Operator: Ponant
Ships: L'Austral, Le Boreal, Le Lyrial
Departures: Mar 2027 to Mar 2029
Visits: Argentina, Uruguay, Brazil
Exclusive Savings
Oceanview
$10,023
Balcony
$10,799
Suite
$18,016
From (Per Person)
A$10,023
Save 400
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Operator: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina
Exclusive Savings
Oceanview
$2,731
Balcony
$2,906
Suite
$4,322
From (Per Person)
A$2,731
Save 62
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Rio de Janeiro to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$693
Balcony
$901
Suite
$2,222
From (Per Person)
A$693
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$874
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$723
Oceanview
$802
Balcony
$1,050
Suite
$1,604
From (Per Person)
A$723
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
$2,164
From (Per Person)
A$1,280
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to São Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$911
Oceanview
$1,069
Balcony
$1,198
Suite
$1,644
From (Per Person)
A$911
Per Person
View Trip
2 Day South America with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Paranagua to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 13 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$464
Suite
$727
From (Per Person)
A$464
Per Person
View Trip
16 Day Chile To La: Peru & Mexico with Celebrity Cruises
Cruise
 (1)

16 Days (15 Nights) Valparaiso to Los Angeles
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 24 March 2028
Visits: Chile, Peru, Ecuador, Guatemala, Mexico, USA
Exclusive Savings
Inside
$2,089
Oceanview
$2,210
Balcony
$2,294
Suite
$5,989
From (Per Person)
A$2,089
Save 1,250
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$7,872
Oceanview
$8,545
Balcony
$11,188
Suite
$15,465
From (Per Person)
A$7,872
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia +3 more, MSC Musica, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$854
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,290
Oceanview
$1,439
Balcony
$1,686
Suite
$2,164
From (Per Person)
A$1,290
Per Person
View Trip
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