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South America Cruises Starting In March 2027, 2028 and 2029

Are you planning a cruise around South America in March 2027, 2028 or 2029? Choose from 128 unique expeditions and cruises with 1,376 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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128 Cruises (1,376 Departures)
128 Cruises (1,376 Departures)
Departures
Duration
2 Days
63 Days
Sub Regions
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Price
$200pp
$134,395pp
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7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Dec 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$7,014
Save 314
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,162
Save 2,162
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Jan 2027 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$15,338
Save 493
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise
 (1)

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Operator: Ponant
Ships: L'Austral, Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina, Uruguay, Brazil
Exclusive Savings
Oceanview
$9,004
Balcony
$9,713
Suite
$16,415
From (Per Person)
A$9,004
Save 305
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 07 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,912
Suite
$3,781
From (Per Person)
A$1,912
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$723
Oceanview
$782
Balcony
$861
Suite
$1,158
From (Per Person)
A$723
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,290
Oceanview
$1,231
Balcony
$1,260
Suite
$2,461
From (Per Person)
A$1,231
Per Person
View Trip
3 Day South America with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Paranagua to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 13 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$570
Suite
$701
From (Per Person)
A$570
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Rio de Janeiro to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,126
Suite
$2,651
From (Per Person)
A$1,126
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,401
Suite
$2,922
From (Per Person)
A$1,401
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$391
Suite
$649
From (Per Person)
A$253
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to São Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$832
Oceanview
$901
Balcony
$921
Suite
$1,218
From (Per Person)
A$832
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,221
Oceanview
$1,270
Balcony
$1,330
Suite
$2,332
From (Per Person)
A$1,221
Per Person
View Trip
16 Day Chile To La: Peru & Mexico with Celebrity Cruises
Cruise
 (1)

16 Days (15 Nights) Valparaiso to Los Angeles
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 24 March 2028
Visits: Chile, Peru, Ecuador, Guatemala, Mexico, USA
Exclusive Savings
Inside
$2,104
Oceanview
$2,225
Balcony
$2,301
Suite
$10,611
From (Per Person)
A$2,104
Save 1,235
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$762
Oceanview
$782
Balcony
$861
Suite
$1,668
From (Per Person)
A$762
Per Person
View Trip
19 Day Valparaiso to Fort Lauderdale, Florida with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Fort Lauderdale
Operator: Silversea
Ship: Silver Nova
Departure: 11 March 2029
Visits: Chile, Peru, Panama, Colombia, Dominican Republic, USA
Exclusive Savings
Balcony
$18,277
Suite
$25,823
From (Per Person)
A$18,277
Save 3,873
Per Person
View Trip
9 Day Chile & Peru Cruise: Arica, Pisco & Lima with Azamara Cruises
Cruise
 (6)

9 Days (8 Nights) Santiago to Lima
Operator: Azamara
Ship: Azamara Journey
Departure: 10 March 2027
Visits: Chile, Peru
Azamara Always Included
Exclusive Savings
Inside
$1,727
Oceanview
$1,963
Balcony
-
Suite
$7,451
From (Per Person)
A$1,727
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Operator: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
$746
Oceanview
$924
Balcony
$1,113
Suite
$1,390
From (Per Person)
A$746
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Operator: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina
Exclusive Savings
Oceanview
$2,731
Balcony
$2,906
Suite
$4,322
From (Per Person)
A$2,731
Save 62
Per Person
View Trip
18 Day South Georgia & Falklands - From Punta Arenas to Montevideo  with HX Expeditions
Cruise
 (1)

18 Days (17 Nights) Santiago to Montevideo
Operator: HX Expeditions
Ship: MS Fram
Departure: 12 March 2027
Visits: Chile, Argentina, Falkland Islands, South Georgia Island, Uruguay
Exclusive Savings
Inside
-
Oceanview
$16,051
Suite
$20,290
From (Per Person)
A$16,051
Save 325
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Exclusive Savings
Inside
$7,951
Oceanview
$8,575
Balcony
$11,297
Suite
$15,703
From (Per Person)
A$7,951
Per Person
View Trip
2 Day South America with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Itajai to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
$325
Oceanview
$335
Balcony
$414
Suite
$489
From (Per Person)
A$325
Per Person
View Trip
13 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Valparaiso
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 12 March 2028
Visits: Argentina, Uruguay, Chile
Exclusive Savings
Inside
$2,793
Oceanview
$3,095
Balcony
$3,232
Suite
$9,565
From (Per Person)
A$2,793
Save 1,675
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Dec 2027
Visits: Brazil
Exclusive Savings
Inside
$587
Oceanview
$607
Balcony
$676
Suite
$1,023
From (Per Person)
A$587
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Rio de Janeiro to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$663
Balcony
$822
Suite
$2,014
From (Per Person)
A$663
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Feb 2027 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$762
Oceanview
$782
Balcony
$852
Suite
$1,198
From (Per Person)
A$762
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Operator: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Mar 2027 to Mar 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,861
Oceanview
$4,207
Balcony
$6,029
Suite
$8,148
From (Per Person)
A$3,861
Per Person
View Trip
2 Day South America with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Paranagua to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 13 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$464
Suite
$727
From (Per Person)
A$464
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia +3 more, MSC Musica, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$607
Balcony
$627
Suite
$874
From (Per Person)
A$607
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visits: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Exclusive Savings
Inside
$4,327
Oceanview
$4,624
Balcony
$5,614
Suite
$8,039
From (Per Person)
A$4,327
Per Person
View Trip
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