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South America Cruises Starting In March 2027, 2028 and 2029

Are you planning a cruise around South America in March 2027, 2028 or 2029? Choose from 98 unique expeditions and cruises with 1,352 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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98 Cruises (1,352 Departures)
98 Cruises (1,352 Departures)
Departures
Duration
2 Days
63 Days
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$200pp
$150,064pp
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10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$9,406
Save 1,922
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Jul 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,190
Save 1,860
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Jul 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$12,772
Save 2,627
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Jul 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,268
Save 2,901
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Mar 2027 to Mar 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Fare Saver
Exclusive Savings
Inside
$3,791
Oceanview
$4,088
Balcony
$5,722
Suite
$7,207
From (Per Person)
A$3,791
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
$733
Oceanview
-
Balcony
$1,238
Suite
$1,486
From (Per Person)
A$733
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$7,476
Oceanview
$8,218
Balcony
$10,842
Suite
$15,049
From (Per Person)
A$7,476
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
-
From (Per Person)
A$1,280
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise
 (2)

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Ponant
Ship: Le Boreal
Departure: 18 March 2028
Visits: Argentina, Uruguay, Brazil
Exclusive Savings
Oceanview
$9,489
Balcony
$10,275
Suite
$17,618
From (Per Person)
A$9,489
Save 271
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visits: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$4,327
Oceanview
$4,624
Balcony
$5,614
Suite
$8,039
From (Per Person)
A$4,327
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,716
Suite
-
From (Per Person)
A$1,280
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania
Ship: Oceania Insignia
Departure: 07 March 2027
Visits: Argentina, Uruguay, Brazil
Your World Inclusions
Exclusive Savings
Inside
$5,735
Oceanview
$6,715
From (Per Person)
A$5,735
Save 2,115
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to São Paulo
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$911
Oceanview
$1,079
Balcony
$1,208
Suite
$1,653
From (Per Person)
A$911
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,736
Suite
-
From (Per Person)
A$1,280
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Inside
$253
Oceanview
$331
Balcony
$400
Suite
$669
From (Per Person)
A$253
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 March 2028
Visits: Argentina
Exclusive Savings
Oceanview
$2,341
Balcony
$2,516
Suite
$4,019
From (Per Person)
A$2,341
Save 59
Per Person
View Trip
18 Day South Georgia & Falklands - From Punta Arenas to Montevideo  with HX Expeditions
Cruise
 (1)

18 Days (17 Nights) Santiago to Montevideo
Cruise Line: HX Expeditions
Ship: MS Fram
Departure: 12 March 2027
Visits: Chile, Argentina, Falkland Islands, South Georgia Island, Uruguay
Exclusive Savings
Inside
-
Oceanview
$18,741
Suite
$24,802
From (Per Person)
A$18,741
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$656
Oceanview
$735
Balcony
$914
Suite
$1,399
From (Per Person)
A$656
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Feb 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$861
Oceanview
$951
Balcony
$1,168
Suite
$1,653
From (Per Person)
A$861
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica +2 more, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$656
Oceanview
$735
Balcony
$854
Suite
$1,211
From (Per Person)
A$656
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,109
Suite
-
From (Per Person)
A$852
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Maceio to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,548
Oceanview
$1,656
Balcony
$1,765
Suite
$2,310
From (Per Person)
A$1,548
Per Person
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$7,196
Save 2,043
Per Person
View Trip
6 Day Galapagos Encounter: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operator: Intrepid
Departures: Jul 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$4,031
Save 1,705
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2027
Visits: Ecuador
Exclusive Savings
From (Per Person)
A$6,455
Save 892
Per Person
View Trip
17 Day Complete Galápagos - Yolita with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$15,507
Save 4,272
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Maceio to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$933
Oceanview
$834
Balcony
$953
Suite
$1,518
From (Per Person)
A$834
Per Person
View Trip
21 Day Galapagos Cruise & Machu Picchu with Wendy Wu Tours
New ReleaseTour + CruiseFlights Included

21 Days Lima to Quito
Cruise Line: Wendy Wu
Departures: Dec 2026 to Mar 2028
Trip Styles: Coach, Small Group, Cruise, Wildlife, Scenic
Visits: Peru, Ecuador
Exclusive Savings
From (Per Person)
A$27,910
Save 2,070
Per Person
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In the Heart of the Wilderness with Ponant
Cruise

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Lyrial
Departure: 02 March 2028
Visits: Argentina, South Georgia Island, Falkland Islands
Exclusive Savings
Oceanview
$25,885
Balcony
$27,728
Suite
$43,597
From (Per Person)
A$25,885
Save 755
Per Person
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,672
Save 3,233
Per Person
View Trip
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Cruise Lines Exploring South & Central America

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