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South America Cruises Starting In March 2027, 2028 and 2029

Are you planning a cruise around South America in March 2027, 2028 or 2029? Choose from 101 unique expeditions and cruises with 1,298 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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101 Cruises (1,298 Departures)
101 Cruises (1,298 Departures)
Departures
Duration
2 Days
63 Days
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$200pp
$133,895pp
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7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,190
Save 1,767
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$9,564
Save 2,635
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,823
Save 453
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Feb 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$861
Oceanview
$951
Balcony
$1,168
Suite
$1,653
From (Per Person)
A$861
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to São Paulo
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$911
Oceanview
$1,069
Balcony
$1,198
Suite
$1,644
From (Per Person)
A$911
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica +2 more, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$656
Oceanview
$735
Balcony
$854
Suite
$1,211
From (Per Person)
A$656
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$401
Suite
$669
From (Per Person)
A$253
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$656
Oceanview
$735
Balcony
$864
Suite
$1,399
From (Per Person)
A$656
Per Person
View Trip
9 Day Chile & Peru Cruise: Arica, Pisco & Lima with Azamara Cruises
Cruise
 (4)

9 Days (8 Nights) Santiago to Lima
Cruise Line: Azamara
Ship: Azamara Journey
Departure: 10 March 2027
Visits: Chile, Peru
Azamara Always Included
Exclusive Savings
Inside
$2,517
Oceanview
$2,870
Balcony
$3,234
Suite
$5,496
From (Per Person)
A$2,517
Save 172
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Cruise Line: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina
Exclusive Savings
Oceanview
$2,731
Balcony
$2,906
Suite
$4,322
From (Per Person)
A$2,731
Save 62
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,109
Suite
-
From (Per Person)
A$852
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,716
Suite
-
From (Per Person)
A$1,280
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$1,033
Balcony
$1,182
Suite
$1,489
From (Per Person)
A$1,033
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visits: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$4,327
Oceanview
$4,624
Balcony
$5,614
Suite
$8,039
From (Per Person)
A$4,327
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise
 (2)

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina, Uruguay, Brazil
Exclusive Savings
Oceanview
$9,441
Balcony
$10,168
Suite
$16,910
From (Per Person)
A$9,441
Save 271
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Mar 2027 to Mar 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Fare Saver
Exclusive Savings
Inside
$3,791
Oceanview
$4,088
Balcony
$5,920
Suite
$7,900
From (Per Person)
A$3,791
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
-
From (Per Person)
A$1,280
Per Person
View Trip
18 Day South Georgia & Falklands - From Punta Arenas to Montevideo  with HX Expeditions
Cruise
 (1)

18 Days (17 Nights) Santiago to Montevideo
Cruise Line: HX Expeditions
Ship: MS Fram
Departure: 12 March 2027
Visits: Chile, Argentina, Falkland Islands, South Georgia Island, Uruguay
Exclusive Savings
Inside
-
Oceanview
$18,741
Suite
$24,802
From (Per Person)
A$18,741
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,716
Suite
-
From (Per Person)
A$1,280
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Fare Saver
Exclusive Savings
Inside
$7,476
Oceanview
$8,218
Balcony
$10,842
Suite
$15,049
From (Per Person)
A$7,476
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Mar 2027 to Mar 2029
Visits: Chile, Argentina
Exclusive Savings
Balcony
$21,077
Suite
$30,151
From (Per Person)
A$21,077
Save 6,378
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operator: Exodus
Departures: Sep 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,808
Save 288
Per Person
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In the Heart of the Wilderness with Ponant
Cruise

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Lyrial
Departure: 02 March 2028
Visits: Argentina, South Georgia Island, Falkland Islands
Exclusive Savings
Oceanview
$27,055
Balcony
$28,898
Suite
$44,767
From (Per Person)
A$27,055
Save 755
Per Person
View Trip
26 Day South American Discovery with Santiago Stopover & Galápagos Cruise with Globus
Tour + Cruise

26 Days Santiago to Guayaquil
Tour Operator: Globus
Departures: Feb 2027 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Chile, Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$22,327
Save 584
Per Person
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Tour Operator: Globus
Departures: Nov 2026 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$11,460
Save 332
Per Person
View Trip
15 Day Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise (South Islands) with Collette
Tour + Cruise

15 Days Lima to Quito
Operator: Collette
Departures: Jul 2027 to May 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,425
Save 3,039
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,548
Oceanview
$1,656
Balcony
$1,726
Suite
$2,310
From (Per Person)
A$1,548
Per Person
View Trip
29 Day Best of South America with Amazon & Galápagos Cruises with APT
Tour + Cruise

29 Days Rio de Janeiro to Guayaquil
Tour Operator: APT
Ships: Delfin III
Departures: Jun 2027 to Sep 2028
Trip Styles: Small Group, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Exclusive Savings
Suite
$40,319
From (Per Person)
A$43,749
Save 3,046
Per Person
View Trip
9 Day Galápagos Islands – In Darwin’s Footsteps (Eastern Route) with HX Expeditions
Cruise

9 Days (8 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Sep 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$10,253
Suite
$13,420
From (Per Person)
A$10,253
Per Person
View Trip
10 Day Galápagos - North, West & Central Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,529
Save 2,350
Per Person
View Trip
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