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South America Cruises Starting In March 2026, 2027 and 2028

Are you planning a cruise around South America in March 2026, 2027 or 2028? Choose from 117 unique expeditions and cruises with 1,537 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the South America cruise that best matches your travel style, budget and dates.
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117 Cruises (1,537 Cruise Departures)
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$7,944
Save 258
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Apr 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$4,661
Save 167
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$10,791
Save 350
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$7,954
Save 258
Per Person
View Trip
14 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

14 Days Lima to Quito
Operated By: Collette
Departures: Jun 2026 to May 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$9,833
Save 170
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2027
Visit: Brazil
Bonus Onboard Credit
Inside
$423
Oceanview
$453
Balcony
$513
Suite
$825
From
US$423
Per Person
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Nov 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$8,310
Save 284
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 March 2028
Visit: Argentina
Inside
-
Oceanview
$1,950
Balcony
$2,080
Suite
$3,040
From
US$1,950
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Feb 2027 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$990
Oceanview
$1,070
Balcony
$1,220
Suite
-
From
US$990
Per Person
View Trip
7 Day Galapagos Express - Central & West Islands aboard the Archipel I with Explore Worldwide
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore Worldwide
Departures: Mar 2026 to Dec 2026
Visit: Galapagos, Ecuador
Exclusive Savings
From
US$4,598
Save 170
Per Person
View Trip
14 Day Argentina & the Chilean Fjords with Viking Cruises
Cruise
 (1)

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Mar 2027 to Mar 2028
Visit: Argentina, Chile
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,995
Suite
$15,995
From
US$9,995
Save 500
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Itajai to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 08 March 2027
Visit: Brazil, Uruguay, Argentina
Inside
$891
Oceanview
$1,110
Balcony
$1,225
Suite
-
From
US$891
Per Person
View Trip
8 Day Galápagos - South & East Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Apr 2026 to Dec 2027
Visit: Ecuador, Galapagos
G's February Sale
Exclusive Savings
From
US$3,491
Save 1,008
Per Person
View Trip
9 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

9 Days (8 Nights) Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 18 March 2026
Visit: Argentina, Uruguay, Brazil
Early Booking Savings
Exclusive Savings
From
US$31,742
Save 39,648
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 08 March 2027
Visit: Chile, Argentina
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,049
Suite
$25,331
From
US$15,049
Save 18,671
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ship: Oosterdam
Departure: 09 March 2027
Visit: Argentina, Uruguay, Falkland Islands, Chile
Fare Saver
Inside
$2,429
Oceanview
$2,629
Balcony
$3,674
Suite
$4,752
From
US$2,429
Per Person
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (4)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Visit: Chile, Peru, Panama
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,340
Suite
-
From
US$3,340
Save 69
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Aug 2026 to Nov 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$8,369
Save 298
Per Person
View Trip
10 Day Galápagos - East, Central, & West Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2026 to Dec 2027
Visit: Ecuador, Galapagos
G's February Sale
Exclusive Savings
From
US$4,710
Save 1,359
Per Person
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Apr 2026 to Dec 2027
Visit: Ecuador, Galapagos
G's February Sale
Exclusive Savings
From
US$6,324
Save 1,825
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,581
Oceanview
$3,727
Balcony
$5,764
Suite
-
From
US$3,581
Save 3,717
Per Person
View Trip
17 Day Complete Galápagos - Eden with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2026 to Dec 2027
Visit: Ecuador, Galapagos
G's February Sale
Exclusive Savings
From
US$8,341
Save 2,408
Per Person
View Trip
8 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: G Adventures
Departures: Apr 2026 to Dec 2027
Visit: Galapagos
G's February Sale
Exclusive Savings
From
US$5,780
Save 1,669
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 14 March 2026
Visit: Uruguay, Argentina, Brazil
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,782
Suite
$3,406
From
US$2,782
Save 78
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Preziosa, MSC Sinfonia
Departures: Feb 2026 to Mar 2027
Visit: Brazil
Bonus Onboard Credit
Inside
$475
Oceanview
$505
Balcony
$565
Suite
$1,375
From
US$475
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Preziosa
Departures: Mar 2026 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$909
Oceanview
$979
Balcony
$1,119
Suite
$1,379
From
US$909
Per Person
View Trip
11 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Ecuador's Amazon with Globus
New ReleaseTour + Cruise

11 Days Quito to Guayaquil
Operated By: Globus
Departures: Mar 2026 to Mar 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$7,265
Save 322
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Chile to Panama with Scenic
New ReleaseCruise

14 Days (13 Nights) Santiago to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 21 March 2027
Visit: Chile, Peru, Ecuador, Colombia, Panama
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,233
Suite
$12,640
From
US$11,233
Save 14,957
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Preziosa
Departures: Mar 2026 to Mar 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Exclusive Savings
Inside
$928
Oceanview
$998
Balcony
$1,108
Suite
$1,388
From
US$928
Save 58
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Mar 2027 to Mar 2028
Visit: Argentina, Uruguay, Brazil
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,739
Suite
$11,582
From
US$9,739
Save 13,251
Per Person
View Trip
Results: 1-30 of 117

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South & Central America Cruises

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Travel Styles

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Countries

Antarctica Argentina Barbados Brazil Chile Ecuador Falkland Islands France French Polynesia Galapagos Morocco Panama Peru Portugal South Georgia Island Spain Uruguay

Cities

Cruises from Baltra Island Cruises from Buenos Aires Cruises from Lima Cruises from Maceio Cruises from Manaus Cruises from Montevideo Cruises from Panama City Cruises from Quito Cruises from Rio de Janeiro Cruises from Salvador Cruises from San Antonio Cruises from Santiago Cruises from Santiago Cruises from Santos Cruises from Sao Paulo Cruises from Ushuaia Cruises from Valparaiso

Routes

Cruises from Baltra Island to Baltra Island Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Buenos Aires to Santiago Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Quito to Quito Cruises from Rio de Janeiro to Buenos Aires Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Ushuaia to Ushuaia

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from Chile to USA Cruises from Brazil to Spain Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Brazil to Argentina Cruises from Chile to Argentina Cruises from Panama to USA Cruises from Peru to Ecuador Cruises from USA to Barbados Cruises from USA to Chile Cruises from USA to Italy Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Ponant Central America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking Central America Cruises Viking South America Cruises

South America Tours

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