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South America Cruises Starting In March 2027, 2028 and 2029

Are you planning a cruise around South America in March 2027, 2028 or 2029? Choose from 138 unique expeditions and cruises with 1,525 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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138 Cruises (1,525 Departures)
138 Cruises (1,525 Departures)
Departures
Duration
2 Days
63 Days
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Price
$200pp
$133,895pp
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7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$6,708
Save 1,350
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,520
Save 1,679
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$15,338
Save 493
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Feb 2027 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$802
Oceanview
$951
Balcony
$1,149
Suite
$1,455
From (Per Person)
A$802
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Rio de Janeiro to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,176
Suite
$2,919
From (Per Person)
A$1,176
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to São Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$911
Oceanview
$1,069
Balcony
$1,198
Suite
$1,644
From (Per Person)
A$911
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,716
Suite
$2,362
From (Per Person)
A$1,280
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,290
Oceanview
$1,439
Balcony
$1,686
Suite
$2,362
From (Per Person)
A$1,290
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 07 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,001
Suite
$3,959
From (Per Person)
A$2,001
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Buenos Aires to Santiago
Operator: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Mar 2027 to Mar 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,792
Oceanview
$4,188
Balcony
$5,920
Suite
$7,900
From (Per Person)
A$3,792
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departures: Jan 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
$2,164
From (Per Person)
A$1,280
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$401
Suite
$669
From (Per Person)
A$253
Per Person
View Trip
9 Day Chile & Peru Cruise: Arica, Pisco & Lima with Azamara Cruises
Cruise
 (6)

9 Days (8 Nights) Santiago to Lima
Operator: Azamara
Ship: Azamara Journey
Departure: 10 March 2027
Visits: Chile, Peru
Azamara Always Included
Exclusive Savings
Inside
$2,688
Oceanview
$2,864
Balcony
$3,550
Suite
$5,863
From (Per Person)
A$2,688
Save 41
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,119
Suite
$1,836
From (Per Person)
A$852
Per Person
View Trip
16 Day Chile To La: Peru & Mexico with Celebrity Cruises
Cruise
 (1)

16 Days (15 Nights) Valparaiso to Los Angeles
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 24 March 2028
Visits: Chile, Peru, Ecuador, Guatemala, Mexico, USA
Exclusive Savings
Inside
$2,104
Oceanview
$2,225
Balcony
$2,301
Suite
$10,414
From (Per Person)
A$2,104
Save 1,235
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$723
Oceanview
$802
Balcony
$1,050
Suite
$1,371
From (Per Person)
A$723
Per Person
View Trip
2 Day South America with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Paranagua to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 13 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$464
Suite
$727
From (Per Person)
A$464
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia +3 more, MSC Musica, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$854
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
33 Day Panama Canal, Inca & South America: Chilean Fjords with Holland America
Cruise
 (3)

33 Days (32 Nights) Buenos Aires to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 06 March 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile +5 more, Peru, Ecuador, Panama, Cayman Islands, USA
Exclusive Savings
Inside
$7,872
Oceanview
$8,545
Balcony
$11,188
Suite
$15,465
From (Per Person)
A$7,872
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Rio de Janeiro to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$693
Balcony
$921
Suite
$2,222
From (Per Person)
A$693
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 09 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,421
Suite
$3,299
From (Per Person)
A$1,421
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Operator: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$954
Balcony
$1,182
Suite
$1,489
From (Per Person)
A$954
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Operator: Oceania
Ship: Oceania Insignia
Departure: 07 March 2027
Visits: Argentina, Uruguay, Brazil
Your World Inclusions
Exclusive Savings
Inside
$7,626
Oceanview
$9,159
Balcony
$11,865
Suite
$14,154
From (Per Person)
A$7,626
Save 2,174
Per Person
View Trip
18 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

18 Days (17 Nights) Santiago to Fort Lauderdale
Operator: Holland America
Ship: Nieuw Amsterdam
Departure: 21 March 2028
Visits: Chile, Peru, Ecuador, Panama, Cayman Islands, USA
Exclusive Savings
Inside
$4,327
Oceanview
$4,624
Balcony
$5,614
Suite
$8,039
From (Per Person)
A$4,327
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$874
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
18 Day South Georgia & Falklands - From Punta Arenas to Montevideo  with HX Expeditions
Cruise
 (1)

18 Days (17 Nights) Santiago to Montevideo
Operator: HX Expeditions
Ship: MS Fram
Departure: 12 March 2027
Visits: Chile, Argentina, Falkland Islands, South Georgia Island, Uruguay
Exclusive Savings
Inside
-
Oceanview
$16,051
Suite
$20,290
From (Per Person)
A$16,051
Save 325
Per Person
View Trip
2 Day South America with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Itajai to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
$305
Oceanview
$335
Balcony
$414
Suite
$489
From (Per Person)
A$305
Per Person
View Trip
3 Day South America with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Paranagua to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 13 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$590
Suite
$730
From (Per Person)
A$590
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Operator: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Mar 2028 to Mar 2029
Visits: Argentina
Exclusive Savings
Oceanview
$2,731
Balcony
$2,906
Suite
$4,322
From (Per Person)
A$2,731
Save 62
Per Person
View Trip
13 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Valparaiso
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 12 March 2028
Visits: Argentina, Uruguay, Chile
Exclusive Savings
Inside
$2,793
Oceanview
$3,095
Balcony
$3,232
Suite
$9,565
From (Per Person)
A$2,793
Save 1,675
Per Person
View Trip
Results: 1-30 of 138

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