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South America Cruises Starting In December 2026, 2027 and 2028

Are you planning a cruise around South America in December 2026, 2027 or 2028? Choose from 87 unique expeditions and cruises with 1,251 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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87 Cruises (1,251 Departures)
87 Cruises (1,251 Departures)
Departures
Duration
4 Days
37 Days
Sub Regions
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Price
$200pp
$133,895pp
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18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (2)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Jan 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Balcony
$10,922
Suite
$18,664
From (Per Person)
A$10,922
Save 1,515
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,190
Save 1,767
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$9,564
Save 2,635
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Feb 2029
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Balcony
$10,824
Suite
$18,664
From (Per Person)
A$10,824
Save 1,515
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,823
Save 453
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,429
Oceanview
$1,676
Balcony
$1,963
Suite
$2,666
From (Per Person)
A$1,429
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica +2 more, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$656
Oceanview
$735
Balcony
$854
Suite
$1,211
From (Per Person)
A$656
Per Person
View Trip
15 Day Patagonia & Argentina Holiday with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 December 2027
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,960
Oceanview
$4,546
Balcony
$4,990
Suite
$15,373
From (Per Person)
A$6,109
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$656
Oceanview
$735
Balcony
$864
Suite
$1,399
From (Per Person)
A$656
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 05 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,783
Oceanview
$1,961
Balcony
$2,347
Suite
$3,317
From (Per Person)
A$1,783
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
$1,468
Oceanview
$1,627
Balcony
$1,904
Suite
-
From (Per Person)
A$1,468
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Inside
$3,675
Oceanview
-
Balcony
$3,891
Suite
$6,217
From (Per Person)
A$3,675
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,109
Suite
-
From (Per Person)
A$852
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 06 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,783
Oceanview
$1,961
Balcony
$2,377
Suite
$3,139
From (Per Person)
A$1,783
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Dec 2026 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Exclusive Savings
Inside
$3,148
Oceanview
$3,445
Balcony
$4,732
Suite
$6,900
From (Per Person)
A$3,148
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,399
Oceanview
$1,647
Balcony
$1,983
Suite
$2,696
From (Per Person)
A$1,399
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Nov 2027
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,032
Oceanview
-
Balcony
$4,159
Suite
$5,363
From (Per Person)
A$3,032
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 21 December 2026
Visits: Brazil
Exclusive Savings
Inside
$1,354
Oceanview
$1,433
Balcony
$1,612
Suite
$1,988
From (Per Person)
A$1,354
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 December 2026
Visits: Brazil
Exclusive Savings
Inside
$696
Oceanview
$795
Balcony
$914
Suite
$1,300
From (Per Person)
A$696
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Feb 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,168
Suite
$1,604
From (Per Person)
A$852
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$2,241
Oceanview
$2,488
Balcony
$2,825
Suite
$3,537
From (Per Person)
A$2,241
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 02 December 2026
Visits: Brazil
Exclusive Savings
Inside
$834
Oceanview
$943
Balcony
$1,092
Suite
$1,419
From (Per Person)
A$834
Per Person
View Trip
15 Day Patagonia & Argentina Cruise with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Cruise Line: Celebrity Cruises
Ships: Celebrity Equinox
Departures: Dec 2026 to Feb 2028
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$2,727
Oceanview
$3,576
Balcony
$2,823
Suite
$8,693
From (Per Person)
A$4,102
Save 94
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operator: Exodus
Departures: Sep 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,808
Save 288
Per Person
View Trip
15 Day Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise (South Islands) with Collette
Tour + Cruise

15 Days Lima to Quito
Operator: Collette
Departures: Jul 2027 to May 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,425
Save 3,039
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$1,548
Oceanview
$1,656
Balcony
$1,726
Suite
$2,310
From (Per Person)
A$1,548
Per Person
View Trip
9 Day Galápagos Islands – In Darwin’s Footsteps (Eastern Route) with HX Expeditions
Cruise

9 Days (8 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Sep 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$10,253
Suite
$13,420
From (Per Person)
A$10,253
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 29 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,914
Suite
$9,064
From (Per Person)
A$2,914
Per Person
View Trip
17 Day Mysteries of the Inca Empire with Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Tour Operator: Cosmos
Departures: Oct 2026 to Dec 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,958
Save 455
Per Person
View Trip
10 Day Galápagos - North, West & Central Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Cruise Line: G Adventures
Departures: Aug 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,529
Save 2,350
Per Person
View Trip
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