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South America Cruises Starting In December 2026, 2027 and 2028

Are you planning a cruise around South America in December 2026, 2027 or 2028? Choose from 91 unique expeditions and cruises with 1,035 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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91 Cruises (1,035 Departures)
91 Cruises (1,035 Departures)
Departures
Duration
3 Days
37 Days
Sub Regions
Start & End Cities
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Cruise Lines
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Price
$200pp
$133,895pp
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18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (2)

18 Days (17 Nights) Buenos Aires to Santiago
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Jan 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Balcony
$12,000
Suite
$18,664
From (Per Person)
A$12,000
Save 1,495
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Sep 2026 to Dec 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,447
Save 1,860
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$11,563
Save 266
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Buenos Aires
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Feb 2029
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Balcony
$12,000
Suite
$18,664
From (Per Person)
A$12,000
Save 1,495
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,399
Oceanview
$1,647
Balcony
$1,983
Suite
$2,696
From (Per Person)
A$1,399
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Santos to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,550
Suite
$3,061
From (Per Person)
A$1,550
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 05 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,694
Oceanview
$1,971
Balcony
$2,377
Suite
$3,337
From (Per Person)
A$1,694
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Holland America
Ship: Nieuw Amsterdam
Departures: Nov 2027 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Exclusive Savings
Inside
$3,148
Oceanview
$3,445
Balcony
$4,732
Suite
$6,910
From (Per Person)
A$3,148
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica +2 more, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$716
Oceanview
$735
Balcony
$854
Suite
$1,211
From (Per Person)
A$716
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,119
Suite
$1,836
From (Per Person)
A$852
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
$1,280
Oceanview
$1,439
Balcony
$1,815
Suite
$4,619
From (Per Person)
A$1,280
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departure: 29 December 2026
Visits: Brazil
Exclusive Savings
Inside
$2,597
Oceanview
$2,736
Balcony
$3,132
Suite
$7,995
From (Per Person)
A$2,597
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
$1,468
Oceanview
$1,627
Balcony
$2,003
Suite
$4,758
From (Per Person)
A$1,468
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$666
Oceanview
$735
Balcony
$924
Suite
$1,248
From (Per Person)
A$666
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departure: 21 December 2026
Visits: Brazil
Exclusive Savings
Inside
$1,354
Oceanview
$1,433
Balcony
$1,612
Suite
$1,988
From (Per Person)
A$1,354
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 27 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,132
Suite
$7,995
From (Per Person)
A$3,132
Per Person
View Trip
15 Day Patagonia & Argentina Holiday with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 December 2027
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$4,156
Oceanview
$4,606
Balcony
$5,191
Suite
$15,260
From (Per Person)
A$4,156
Save 2,427
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 06 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,793
Oceanview
$1,971
Balcony
$2,377
Suite
$3,159
From (Per Person)
A$1,793
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Buenos Aires to Santiago
Operator: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Nov 2027
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,444
Oceanview
-
Balcony
$3,776
Suite
$5,176
From (Per Person)
A$3,444
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Inside
$3,195
Oceanview
-
Balcony
$4,417
Suite
$5,136
From (Per Person)
A$3,195
Per Person
View Trip
3 Day South America with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Santos to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$887
Suite
$1,156
From (Per Person)
A$887
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 02 December 2026
Visits: Brazil
Exclusive Savings
Inside
$834
Oceanview
$943
Balcony
$1,092
Suite
$1,419
From (Per Person)
A$834
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Feb 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,178
Suite
$1,604
From (Per Person)
A$852
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 26 December 2026
Visits: Brazil
Exclusive Savings
Inside
$2,597
Oceanview
-
Balcony
$3,132
Suite
$9,698
From (Per Person)
A$2,597
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Buenos Aires to Buenos Aires
Operator: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Argentina, Brazil, Uruguay
Exclusive Savings
Inside
$2,241
Oceanview
$2,488
Balcony
$2,844
Suite
$3,537
From (Per Person)
A$2,241
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,399
Oceanview
$1,647
Balcony
$1,963
Suite
$2,666
From (Per Person)
A$1,399
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Divina
Departure: 18 December 2026
Visits: Brazil
Exclusive Savings
Inside
$666
Oceanview
$795
Balcony
$914
Suite
$1,310
From (Per Person)
A$666
Per Person
View Trip
10 Day Galápagos - North, West & Central Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Oct 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,407
Save 222
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: G Adventures
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,534
Save 243
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operator: Silversea
Ship: Silver Origin
Departures: Nov 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Balcony
$20,198
Suite
$26,910
From (Per Person)
A$20,198
Save 8,153
Per Person
View Trip
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