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South America Cruises Starting In December 2026, 2027 and 2028

Are you planning a cruise around South America in December 2026, 2027 or 2028? Choose from 108 unique expeditions and cruises with 1,444 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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108 Cruises (1,444 Departures)
108 Cruises (1,444 Departures)
Departures
Duration
3 Days
37 Days
Sub Regions
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Price
$200pp
$155,595pp
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18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (2)

18 Days (17 Nights) Buenos Aires to Santiago
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Jan 2027 to Jan 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Balcony
$14,009
Suite
$22,339
From (Per Person)
A$14,009
Save 316
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$6,708
Save 314
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,152
Save 2,797
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (1)

18 Days (17 Nights) Santiago to Buenos Aires
Operator: Viking
Ships: Viking Jupiter, Viking Star
Departures: Dec 2026 to Feb 2029
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Balcony
$12,000
Suite
$18,664
From (Per Person)
A$12,000
Save 1,495
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,823
Save 493
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 02 December 2026
Visits: Brazil
Exclusive Savings
Inside
$834
Oceanview
$943
Balcony
$1,092
Suite
$1,419
From (Per Person)
A$834
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Santos to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$1,035
Balcony
$1,550
Suite
$3,061
From (Per Person)
A$1,035
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Dec 2027
Visits: Brazil
Exclusive Savings
Inside
$2,538
Oceanview
$2,755
Balcony
$3,132
Suite
$5,441
From (Per Person)
A$2,538
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 05 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,694
Oceanview
$1,971
Balcony
$2,357
Suite
$3,892
From (Per Person)
A$1,694
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
$1,300
Oceanview
$1,439
Balcony
$1,716
Suite
$3,807
From (Per Person)
A$1,300
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Dec 2027
Visits: Brazil
Exclusive Savings
Inside
$2,538
Oceanview
$2,755
Balcony
$3,132
Suite
$5,441
From (Per Person)
A$2,538
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Itajai to Itajai
Operator: MSC Cruises
Ship: MSC Seaview
Departure: 06 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,694
Oceanview
$1,971
Balcony
$2,387
Suite
$3,159
From (Per Person)
A$1,694
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Divina
Departure: 18 December 2026
Visits: Brazil
Exclusive Savings
Inside
$666
Oceanview
$795
Balcony
$914
Suite
$1,310
From (Per Person)
A$666
Per Person
View Trip
3 Day South America with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Santos to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departure: 20 December 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$730
From (Per Person)
A$730
Per Person
View Trip
15 Day Patagonia & Argentina Holiday with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 December 2027
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,752
Oceanview
$4,119
Balcony
$4,730
Suite
$13,912
From (Per Person)
A$3,752
Save 2,162
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
$1,488
Oceanview
$1,627
Balcony
$2,003
Suite
$4,758
From (Per Person)
A$1,488
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2027 to Jan 2028
Visits: Brazil
Exclusive Savings
Inside
$1,332
Oceanview
$1,461
Balcony
$1,817
Suite
$2,269
From (Per Person)
A$1,332
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$874
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia +3 more, MSC Musica, MSC Seaview, MSC Virtuosa
Departures: Nov 2026 to Apr 2028
Visits: Brazil
Exclusive Savings
Inside
$617
Oceanview
$696
Balcony
$854
Suite
$1,169
From (Per Person)
A$617
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Buenos Aires to Santiago
Operator: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Nov 2027
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$3,444
Oceanview
-
Balcony
$3,776
Suite
$5,176
From (Per Person)
A$3,444
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,119
Suite
$1,836
From (Per Person)
A$852
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Dec 2027 to Feb 2028
Visits: Brazil
Exclusive Savings
Inside
$723
Oceanview
$802
Balcony
$1,030
Suite
$1,371
From (Per Person)
A$723
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Holland America
Ship: Nieuw Amsterdam
Departures: Nov 2027 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,148
Oceanview
$3,445
Balcony
$4,732
Suite
$6,910
From (Per Person)
A$3,148
Per Person
View Trip
15 Day Best Of South America with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Operator: Celebrity Cruises
Ships: Celebrity Equinox
Departures: Dec 2026 to Feb 2029
Visits: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$2,677
Oceanview
$3,016
Balcony
$2,711
Suite
$9,195
From (Per Person)
A$2,677
Save 13,402
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Sao Paulo to Sao Paulo
Operator: MSC Cruises
Ship: MSC Divina
Departure: 21 December 2026
Visits: Brazil
Exclusive Savings
Inside
$1,414
Oceanview
$1,433
Balcony
$1,612
Suite
$1,988
From (Per Person)
A$1,414
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Operator: MSC Cruises
Ships: MSC Divina, MSC Meraviglia, MSC Musica
Departures: Nov 2026 to Mar 2028
Visits: Brazil
Exclusive Savings
Inside
$723
Oceanview
$802
Balcony
$1,050
Suite
$1,604
From (Per Person)
A$723
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Santiago to Buenos Aires
Operator: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Dec 2027
Visits: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
Inside
$3,274
Oceanview
-
Balcony
$4,457
Suite
$4,720
From (Per Person)
A$3,274
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Paranagua to Paranagua
Operator: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Dec 2027
Visits: Brazil
Exclusive Savings
Inside
$2,538
Oceanview
$2,755
Balcony
$3,161
Suite
$10,104
From (Per Person)
A$2,538
Save 96
Per Person
View Trip
7 Day Galápagos Islands - Nature and Wildlife Expedition Cruise (Northern Route) with HX Expeditions
Cruise

7 Days (6 Nights) Quito to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Nov 2026 to Dec 2026
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$9,130
Suite
-
From (Per Person)
A$9,130
Save 264
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operator: Exodus
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,085
Save 1,720
Per Person
View Trip
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