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Central America Cruises Starting In October 2026 and 2027

Are you planning a cruise to Central America in October 2026 or 2027? Choose from 39 unique cruises and 178 departures operated by Central America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Central America cruise that best matches your travel style, budget and dates.
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39 Cruises (178 Cruise Departures)
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 04 October 2026
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,559
Oceanview
$2,259
Balcony
$2,299
Suite
$3,749
From
US$1,559
Per Person
View Trip
21 Day Panama Canal & Pacific Coast with Princess
Cruise
 (6)

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 09 October 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,999
Oceanview
$2,294
Balcony
$3,160
Suite
$5,014
From
US$1,999
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departures: Oct 2027 to Apr 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,399
Oceanview
$1,599
Balcony
$2,159
Suite
$3,709
From
US$1,399
Per Person
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Enchantment of the Seas
Departures: May 2026 to Oct 2026
Visit: USA, Mexico, Belize, Honduras
Exclusive Savings
Inside
$623
Oceanview
$731
Balcony
$1,170
Suite
$1,185
From
US$623
Save 2,504
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Emerald Princess
Departure: 24 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,387
Oceanview
$1,497
Balcony
$2,497
Suite
$3,357
From
US$1,387
Per Person
View Trip
15 Day Panama Canal & Central America with Viking Cruises
Cruise
 (8)

15 Days (14 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2026 to Feb 2028
Visit: USA, Jamaica, Panama, Costa Rica, Honduras, Belize, Mexico
Flights Included
Viking $499 Air Deal
Inside
-
Oceanview
-
Balcony
$5,099
Suite
$7,999
From
US$5,099
Per Person
View Trip
18 Day Panama Canal: LA to Miami Halloween with Virgin Voyages
Cruise
 (1)

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Virgin Voyages
Ship: Brilliant Lady
Departure: 29 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Limited Time Offer
Inside
$1,854
Oceanview
$2,363
Balcony
$2,534
Suite
$9,503
From
US$1,854
Per Person
View Trip
6 Day Caribbean And Antilles with MSC Cruises
Cruise

6 Days (5 Nights) Galveston to Galveston
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 24 October 2027
Visit: USA, Mexico
Inside
$549
Oceanview
$639
Balcony
$719
Suite
-
From
US$549
Per Person
View Trip
18 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

18 Days (17 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 19 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Bahamas
Inside
$2,359
Oceanview
$3,159
Balcony
$3,909
Suite
$4,509
From
US$2,359
Per Person
View Trip
19 Day Transamerican Treasures with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,899
Suite
$12,099
From
US$6,899
Save 6,899
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Bonus Onboard Credit
Exclusive Savings
Inside
$1,729
Oceanview
$2,159
Balcony
$2,969
Suite
$10,649
From
US$1,729
Save 696
Per Person
View Trip
17 Day Panama Canal - Ocean To Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 10 October 2027
Visit: USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$1,399
Oceanview
$1,699
Balcony
$2,299
Suite
$3,449
From
US$1,399
Per Person
View Trip
8 Day Perfect Day Cococay & West Caribbean with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Icon Of The Seas
Departures: Apr 2026 to Jul 2027
Visit: USA, Mexico, Honduras, Bahamas
Bonus Onboard Credit
Exclusive Savings
Inside
$1,171
Oceanview
$1,474
Balcony
$1,522
Suite
$2,318
From
US$1,249
Save 1,230
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visit: Bahamas, Colombia, Panama
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,016
Suite
$14,153
From
US$12,016
Save 529
Per Person
View Trip
24 Day Panama Canal & Pacific COast with Princess
Cruise

24 Days (23 Nights) Vancouver to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 03 October 2027
Visit: Canada, USA, Mexico, Panama, Aruba
Princess Standard
Sanctuary Collection
Inside
$2,524
Oceanview
-
Balcony
$3,648
Suite
$5,815
From
US$2,524
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visit: USA, Bahamas, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$26,140
Suite
$56,695
From
US$26,140
Per Person
View Trip
20 Day Panama Canal Repositioning Cruise From Los Angeles To New York with Norwegian Cruise Line
Cruise

20 Days (19 Nights) Los Angeles to New York
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$2,029
Oceanview
$2,199
Balcony
$2,549
Suite
$3,049
From
US$2,029
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise
 (3)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 02 October 2026
Visit: USA, Mexico, Guatemala, El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,629
Oceanview
$1,689
Balcony
$2,759
Suite
$4,939
From
US$1,629
Per Person
View Trip
22 Day Panama Canal with Holland America
Cruise

22 Days (21 Nights) Seattle to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: USA, Canada, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,299
Oceanview
$2,399
Balcony
$3,599
Suite
$6,399
From
US$2,299
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Bliss
Departure: 13 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$1,879
Oceanview
$2,049
Balcony
$2,399
Suite
$2,899
From
US$1,879
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise From Los Angeles To Miami with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Joy
Departure: 07 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Jamaica
Inside
$2,049
Oceanview
$2,449
Balcony
$3,049
Suite
$3,449
From
US$2,049
Per Person
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: Canada, USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,139
Oceanview
$2,229
Balcony
$3,419
Suite
$5,799
From
US$2,139
Per Person
View Trip
8 Day Harvest Caye, Cozumel & Roatan with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Aura, Norwegian Luna
Departures: Nov 2026 to Mar 2028
Visit: USA, Honduras, Belize, Mexico
Inside
$959
Oceanview
$1,019
Balcony
$1,249
Suite
$1,899
From
US$959
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,899
Oceanview
$1,969
Balcony
$3,069
Suite
$5,239
From
US$1,899
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Oct 2026 to Dec 2027
Visit: USA, Bonaire, Aruba, Curacao (+7 more), Dominican Republic, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Inside
$1,931
Oceanview
$2,487
Balcony
$2,701
Suite
$13,511
From
US$1,931
Per Person
View Trip
13 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (1)

13 Days (12 Nights) Fort-de-France to Colon
Cruise Line: Ponant
Ship: Le Bellot
Departure: 26 October 2026
Visit: Martinique, Guadeloupe, Saint Lucia, Saint Vincent, Bonaire, Colombia, Panama
Inside
-
Oceanview
-
Balcony
$7,550
Suite
$11,910
From
US$7,550
Per Person
View Trip
22 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

22 Days (21 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 31 October 2027
Visit: USA, Jamaica, Colombia, Panama (+7 more), Costa Rica, Honduras, Belize, Bonaire, Aruba, Dominican Republic, Cayman Islands
Inside
$2,031
Oceanview
$2,251
Balcony
$2,801
Suite
-
From
US$2,031
Per Person
View Trip
12 Day Pristine Islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Bridgetown to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 20 October 2027
Visit: Barbados, Saint Lucia, Saint Vincent, Curacao, Colombia, Panama
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,363
Suite
$13,590
From
US$11,363
Save 1,067
Per Person
View Trip
18 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

18 Days (17 Nights) Los Angeles to Tampa
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 01 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica (+4 more), Panama, Colombia, Jamaica, Cayman Islands
Exclusive Savings
Inside
$1,435
Oceanview
$2,782
Balcony
$4,062
Suite
$15,234
From
US$1,435
Save 614
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (3)

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Nov 2026 to Mar 2028
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize
Inside
$943
Oceanview
$1,063
Balcony
$1,363
Suite
$3,873
From
US$943
Per Person
View Trip
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