Home > Cruises > South America Cruises > September

South America Cruises Starting In September 2026, 2027, 2028 and 2029

Are you planning a cruise around South America in September 2026, 2027, 2028 or 2029? Choose from 67 unique expeditions and cruises with 1,178 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
Filter Results
Departures
Duration
6 Days
81 Days
Sub Regions
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$200pp
$133,895pp
Countries
Show More...
Filter Results
67 Cruises (1,178 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
A$18,667
Save 446
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$9,406
Save 1,922
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,864
Save 2,093
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$12,772
Save 2,627
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,738
Save 3,403
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
A$16,313
Save 1,051
Per Person
View Trip
7 Day Galapagos Express - Central & West Islands aboard the Archipel I with Explore Worldwide
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore Worldwide
Departures: Jun 2026 to Dec 2026
Visit: Galapagos, Ecuador
Sign Up Savings
Exclusive Savings
From
A$6,852
Save 607
Per Person
View Trip
7 Day Galapagos Adventure: Northern Islands (Grand Daphne) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,001
Save 2,156
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,487
Save 1,546
Per Person
View Trip
18 Day Spirit of Peru with Amazon and Galápagos Cruises with APT
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operated By: APT
Ships: Delfin III
Departures: Jul 2027 to Sep 2028
Visit: Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$27,527
From
A$29,977
Save 2,018
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departure: 28 September 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
A$19,499
Save 464
Per Person
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$11,460
Save 277
Per Person
View Trip
17 Day Complete Galápagos - Yolita with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$15,193
Save 4,186
Per Person
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,094
Save 3,830
Per Person
View Trip
23 Day Legacy of the Incas with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

23 Days Lima to Guayaquil
Operated By: Globus
Departure: 18 September 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$19,739
Save 490
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,775
Save 1,652
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Quito
Operated By: Tauck
Ship: Silver Origin
Departures: Apr 2027 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
A$27,290
Per Person
View Trip
10 Day Classic Galapagos: Central Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,122
Save 2,973
Per Person
View Trip
20 Day Spirit of Peru with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

20 Days Lima to Guayaquil
Operated By: APT
Departures: May 2027 to Oct 2028
Visit: Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$29,466
Save 2,085
Per Person
View Trip
8 Day Pure Galapagos (Grand Daphne) with Intrepid Travel
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$6,788
Save 2,968
Per Person
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,048
Save 1,434
Per Person
View Trip
15 Day Spirit of Peru with Galápagos Cruise with APT
New ReleaseTour + Cruise

15 Days Lima to Guayaquil
Operated By: APT
Departures: May 2027 to Nov 2028
Visit: Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$20,642
Save 1,889
Per Person
View Trip
8 Day Galápagos - South & East Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,801
Save 2,248
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Aug 2026 to Mar 2028
Visit: Ecuador, Galapagos
Last Minute Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,651
Suite
$27,538
From
A$14,651
Save 7,096
Per Person
View Trip
9 Day Island Hopping in the Galapagos with Exodus Tours
New ReleaseCruise

9 Days (8 Nights) Quito to Quito
Operated By: Exodus Tours
Departures: Oct 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,935
Save 672
Per Person
View Trip
26 Day Best of South America with Galápagos Cruise with APT
New ReleaseTour + Cruise

26 Days Rio de Janeiro to Guayaquil
Operated By: APT
Departures: Apr 2027 to Nov 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$33,435
Save 2,118
Per Person
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$13,408
Save 339
Per Person
View Trip
16 Day Galápagos Islands - Nine of the Best Isles plus Machu Picchu with HX Expeditions
Cruise

16 Days (15 Nights) Lima to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Aug 2026 to Mar 2028
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
$19,859
Balcony
-
Suite
$25,471
From
A$19,859
Per Person
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,196
Save 2,043
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$13,420
Save 317
Per Person
View Trip
Results: 1-30 of 67

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

Active Adventures Coach Cruises Luxury Cruises Short Cruise Breaks Wildlife Cruises

Countries

Antarctica Argentina Barbados Brazil Chile Ecuador Falkland Islands France Galapagos Morocco Panama Peru Portugal South Georgia Island Spain Uruguay

Cities

Cruises from Lima Cruises from Manaus Cruises from Quito Cruises from Rio de Janeiro Cruises from Santiago Cruises from Santiago

Routes

Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Quito to Quito Cruises from Rio de Janeiro to Buenos Aires Cruises from San Antonio to Buenos Aires Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago

Country Routes

Cruises from Peru to Argentina Cruises from Iceland to USA Cruises from Chile to USA Cruises from Peru to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from Panama to USA Cruises from Peru to Ecuador Cruises from USA to Argentina Cruises from USA to Chile

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

All South America Tours Amazon Tours Argentina Tours Brazil Tours Chile Tours Colombia Tours Ecuador Tours Galapagos Tours Patagonia Tours Peru Tours

© 2010-2026. Global Journeys. You're viewing our site in Australian dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations