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South America Cruises Starting In September 2026, 2027, 2028 and 2029

Are you planning a cruise around South America in September 2026, 2027, 2028 or 2029? Choose from 69 unique expeditions and cruises with 1,155 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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69 Cruises (1,155 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Flash Sale
Exclusive Savings
From
A$17,770
Save 1,307
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$9,406
Save 1,922
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,864
Save 2,093
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$12,772
Save 2,627
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,738
Save 3,403
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Flash Sale
Exclusive Savings
From
A$15,417
Save 1,258
Per Person
View Trip
11 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Ecuador's Amazon with Globus
New ReleaseTour + Cruise

11 Days Quito to Guayaquil
Operated By: Globus
Departures: Jun 2026 to Dec 2026
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$11,669
Save 350
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$13,420
Save 317
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2026 to Mar 2028
Visit: Ecuador, Galapagos
Last Minute Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,357
Suite
$28,420
From
A$14,357
Save 5,486
Per Person
View Trip
10 Day Galápagos - East, Central, & West Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,196
Save 2,084
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Sep 2026 to Oct 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
A$19,499
Save 486
Per Person
View Trip
9 Day Galápagos Islands – In Darwin’s Footsteps (Eastern Route) with HX Expeditions
Cruise

9 Days (8 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Jul 2026 to Mar 2028
Visit: Ecuador, Galapagos
Inside
-
Oceanview
$10,357
Balcony
-
Suite
$13,556
From
A$10,357
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operated By: G Adventures
Departures: Sep 2026 to Dec 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$13,327
Save 300
Per Person
View Trip
10 Day Classic Galapagos: Central Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,985
Save 3,522
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador
Exclusive Savings
From
A$5,021
Save 2,298
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,487
Save 1,546
Per Person
View Trip
6 Day Galapagos Encounter: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,031
Save 1,705
Per Person
View Trip
10 Day Classic Galapagos: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,136
Save 2,973
Per Person
View Trip
7 Day Galapagos Express - Central & West Islands aboard the Archipel I with Explore Worldwide
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore Worldwide
Departures: Jun 2026 to Dec 2026
Visit: Galapagos, Ecuador
Sign Up Savings
Exclusive Savings
From
A$6,852
Save 607
Per Person
View Trip
7 Day Galápagos Islands – Iconic Wildlife & Sublime Scenery (Western Route) with HX Expeditions
Cruise

7 Days (6 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Jul 2026 to Sep 2026
Visit: Ecuador, Galapagos
Inside
-
Oceanview
$9,498
Balcony
-
Suite
-
From
A$9,498
Per Person
View Trip
7 Day Galápagos Islands - Nature and Wildlife Expedition Cruise (Northern Route) with HX Expeditions
Cruise

7 Days (6 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Jul 2026 to Dec 2026
Visit: Ecuador, Galapagos
Inside
-
Oceanview
$9,071
Balcony
-
Suite
$12,934
From
A$9,071
Per Person
View Trip
6 Day Galapagos at a Glance: Southern Islands (Grand Daphne) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,921
Save 977
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Sep 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,371
Save 915
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 19 September 2026
Visit: Galapagos, Ecuador
Last Minute Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,161
Suite
$30,772
From
A$14,161
Save 289
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary B) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,352
Save 271
Per Person
View Trip
7 Day Galápagos Land & Sea - Central & South Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,472
Save 2,047
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary C) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,352
Save 271
Per Person
View Trip
14 Day Galápagos Islands – In Darwin’s Footsteps plus Machu Picchu with HX Expeditions
Cruise

14 Days (13 Nights) Lima to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Aug 2026 to Mar 2028
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
$16,842
Balcony
-
Suite
$20,041
From
A$16,842
Per Person
View Trip
17 Day Complete Galápagos - Eden with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: G Adventures
Departures: Sep 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$13,390
Save 3,689
Per Person
View Trip
16 Day Galápagos Islands - Nine of the Best Isles plus Machu Picchu with HX Expeditions
Cruise

16 Days (15 Nights) Lima to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Aug 2026 to Mar 2028
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
$19,911
Balcony
-
Suite
$25,523
From
A$19,911
Per Person
View Trip
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