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South America Cruises Starting In September 2026, 2027, 2028 and 2029

Are you planning a cruise around South America in September 2026, 2027, 2028 or 2029? Choose from 63 unique expeditions and cruises with 1,120 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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63 Cruises (1,120 Departures)
63 Cruises (1,120 Departures)
Departures
Duration
6 Days
81 Days
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Price
$200pp
$133,895pp
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operator: Cosmos
Departures: Nov 2026 to Oct 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$18,556
Save 604
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,871
Save 2,366
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$11,563
Save 266
Per Person
View Trip
15 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with Globus
New ReleaseTour + Cruise
 (1)

15 Days Lima to Guayaquil
Operator: Globus
Departures: Mar 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,725
Save 623
Per Person
View Trip
22 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Nazca Lines & the Amazon with Globus
New ReleaseTour + Cruise
 (1)

22 Days Lima to Quito
Operator: Globus
Departures: Mar 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$20,807
Save 798
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,350
Save 2,901
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operator: Cosmos
Departures: Nov 2026 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,127
Save 556
Per Person
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operator: Cosmos
Departures: Jun 2027 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,049
Save 337
Per Person
View Trip
9 Day Galápagos Islands – In Darwin’s Footsteps (Eastern Route) with HX Expeditions
Cruise

9 Days (8 Nights) Quito to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Oct 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Oceanview
$10,092
Suite
$13,259
From (Per Person)
A$10,092
Save 295
Per Person
View Trip
7 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operator: Globus
Departures: Aug 2026 to Mar 2028
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,031
Save 276
Per Person
View Trip
14 Day Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu with HX Expeditions
Cruise

14 Days (13 Nights) Lima to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Oct 2026 to Mar 2028
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
Oceanview
$16,513
Suite
$19,680
From (Per Person)
A$16,513
Save 372
Per Person
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operator: G Adventures
Departures: Sep 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$4,733
Save 1,706
Per Person
View Trip
7 Day Galapagos Express - Central & West Islands aboard the Archipel I with Explore Worldwide
Cruise

7 Days (6 Nights) Quito to Quito
Operator: Explore
Departures: Aug 2026 to Dec 2026
Visits: Galapagos, Ecuador
Exclusive Savings
From (Per Person)
A$6,852
Save 607
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operator: Exodus
Departures: Sep 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,056
Save 1,371
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operator: Silversea
Ship: Silver Origin
Departures: Oct 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Balcony
$16,660
Suite
$28,430
From (Per Person)
A$16,660
Save 5,497
Per Person
View Trip
10 Day Classic Galapagos: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operator: Intrepid
Departure: 19 September 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,548
Save 2,973
Per Person
View Trip
6 Day Galapagos at a Glance: Southern Islands (Grand Daphne) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operator: Intrepid
Departures: Aug 2026 to Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$4,649
Save 1,203
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary C) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operator: Exodus
Departures: Sep 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,352
Save 271
Per Person
View Trip
6 Day Galapagos Escape - Solaris (Itinerary B) with Exodus Tours
Cruise

6 Days (5 Nights) Quito to Guayaquil
Operator: Exodus
Departures: Sep 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,551
Save 277
Per Person
View Trip
16 Day Galápagos Islands - Nine of the Best Isles plus Machu Picchu with HX Expeditions
Cruise

16 Days (15 Nights) Lima to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Dec 2026 to Mar 2028
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
Oceanview
$20,282
Suite
$25,107
From (Per Person)
A$20,282
Save 419
Per Person
View Trip
15 Day Spirit of Peru with Galápagos Cruise with APT
New ReleaseTour + Cruise

15 Days Lima to Guayaquil
Operator: APT
Departures: Jun 2027 to Nov 2028
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$20,642
Save 1,889
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operator: G Adventures
Departures: Sep 2026 to Dec 2027
Visits: Ecuador
Exclusive Savings
From (Per Person)
A$5,738
Save 1,676
Per Person
View Trip
15 Day Ecuador: Natural Wonders & Ancient Cultures with Galápagos Cruise with Globus
New ReleaseTour + Cruise

15 Days Quito to Guayaquil
Operator: Globus
Departures: Nov 2026 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,584
Save 570
Per Person
View Trip
8 Day Pure Galapagos (Grand Daphne) with Intrepid Travel
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: Intrepid
Departures: Aug 2026 to Sep 2026
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$7,321
Save 2,530
Per Person
View Trip
7 Day Galápagos Land & Sea - Central & South Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operator: G Adventures
Departures: Sep 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,111
Save 1,460
Per Person
View Trip
8 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: G Adventures
Departures: Oct 2026 to Dec 2028
Visits: Galapagos
Exclusive Savings
From (Per Person)
A$8,427
Save 2,408
Per Person
View Trip
21 Day Ecuador: Natural Wonders & Ancient Cultures with Peru & the Galápagos Cruise with Globus
New ReleaseTour + Cruise

21 Days Lima to Guayaquil
Operator: Globus
Departures: Apr 2027 to Oct 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,064
Save 700
Per Person
View Trip
15 Day Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise (West Islands) with Collette
Tour + Cruise

15 Days Lima to Quito
Operator: Collette
Departures: Aug 2026 to Apr 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$13,111
Save 2,974
Per Person
View Trip
18 Day Spirit of Peru with Amazon and Galápagos Cruises with APT
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operator: APT
Ships: Delfin III
Departures: Jul 2027 to Sep 2028
Trip Styles: Small Group, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
Suite
$27,527
From (Per Person)
A$29,977
Save 2,018
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$11,800
Save 1,579
Per Person
View Trip
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