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South America Cruises Starting In May 2027 and 2028

Are you planning a cruise around South America in May 2027 or 2028? Choose from 56 unique expeditions and cruises with 1,325 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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56 Cruises (1,325 Departures)
56 Cruises (1,325 Departures)
Departures
Duration
6 Days
31 Days
Sub Regions
Start & End Cities
Cruise Lines
Price
$200pp
$155,595pp
Countries
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Oct 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$18,556
Save 446
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$6,708
Save 314
Per Person
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,152
Save 2,797
Per Person
View Trip
15 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with Globus
New ReleaseTour + Cruise
 (1)

15 Days Lima to Guayaquil
Operator: Globus
Departures: Jun 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,725
Save 623
Per Person
View Trip
22 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galapagos with the Nazca Lines & the Amazon with Globus
New ReleaseTour + Cruise
 (1)

22 Days Lima to Quito
Operator: Globus
Departures: May 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$19,294
Save 798
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$14,823
Save 493
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operator: Cosmos
Departures: Jan 2027 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,127
Save 396
Per Person
View Trip
14 Day Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu with HX Expeditions
Cruise

14 Days (13 Nights) Lima to Quito
Operator: HX Expeditions
Ship: MS Santa Cruz II
Departures: Nov 2026 to Mar 2028
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
Oceanview
$13,900
Suite
$17,263
From (Per Person)
A$13,900
Save 353
Per Person
View Trip
15 Day Ecuador: Natural Wonders & Ancient Cultures with Galápagos Cruise with Globus
New ReleaseTour + Cruise

15 Days Quito to Guayaquil
Operator: Globus
Departures: Nov 2026 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$10,584
Save 570
Per Person
View Trip
15 Day Spirit of Peru with Galápagos Cruise with APT
New ReleaseTour + Cruise

15 Days Lima to Guayaquil
Operator: APT
Departures: Sep 2027 to Nov 2028
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$22,406
Save 1,889
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: G Adventures
Departures: Nov 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$9,870
Save 1,979
Per Person
View Trip
17 Day Complete Galápagos - Yolita with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$16,876
Save 3,383
Per Person
View Trip
8 Day Galapagos Outer Loop Itinerary with Celebrity Cruises
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: Celebrity Cruises
Ship: Celebrity Flora
Departures: Feb 2027 to Dec 2028
Visits: Galapagos
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$14,310
From (Per Person)
A$14,310
Save 9,697
Per Person
View Trip
9 Day Island Hopping in the Galapagos with Exodus Tours
New ReleaseCruise

9 Days (8 Nights) Quito to Quito
Operator: Exodus
Departures: Nov 2026 to Dec 2027
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$7,382
Save 1,570
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operator: Globus
Departures: Mar 2027 to Nov 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$20,172
Save 583
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operator: Silversea
Ship: Silver Origin
Departures: Nov 2026 to Mar 2028
Visits: Ecuador, Galapagos
Exclusive Savings
Balcony
$19,061
Suite
$25,529
From (Per Person)
A$19,061
Save 1,136
Per Person
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operator: Globus
Departures: Apr 2027 to Nov 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$23,054
Save 654
Per Person
View Trip
26 Day South American Discovery with Santiago Stopover & Galápagos Cruise with Globus
Tour + Cruise

26 Days Santiago to Guayaquil
Operator: Globus
Departures: Mar 2027 to Nov 2028
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Chile, Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$22,327
Save 616
Per Person
View Trip
18 Day Peru & Ecuador: Machu Picchu, the Sacred Valley & the Galápagos with the Nazca Lines with Globus
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operator: Globus
Departures: May 2027 to Nov 2028
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$15,288
Save 675
Per Person
View Trip
8 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operator: G Adventures
Departures: Oct 2026 to Dec 2028
Visits: Galapagos
Exclusive Savings
From (Per Person)
A$8,195
Save 2,954
Per Person
View Trip
20 Day Spirit of Peru with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

20 Days Lima to Guayaquil
Operator: APT
Departures: May 2027 to Oct 2028
Trip Styles: Small Group, Cruise, Rail, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$29,466
Save 2,085
Per Person
View Trip
6 Day Galapagos Encounter: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operator: Intrepid
Departures: Oct 2026 to Dec 2028
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$5,754
Save 290
Per Person
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operator: G Adventures
Departures: Nov 2026 to Dec 2027
Visits: Ecuador
Exclusive Savings
From (Per Person)
A$5,911
Save 1,628
Per Person
View Trip
29 Day Best of South America with Amazon & Galápagos Cruises with APT
Tour + Cruise

29 Days Rio de Janeiro to Guayaquil
Operator: APT
Ships: Delfin III
Departures: Jun 2027 to Sep 2028
Trip Styles: Small Group, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Exclusive Savings
Suite
$40,319
From (Per Person)
A$43,749
Save 3,046
Per Person
View Trip
31 Day Best of South America with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

31 Days Rio de Janeiro to Guayaquil
Operator: APT
Departures: May 2027 to Oct 2028
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$42,257
Save 3,126
Per Person
View Trip
13 Day Peru & Galápagos Odyssey with Cox & Kings
New ReleaseTour + Cruise

13 Days Lima to Guayaquil
Operator: Cox & Kings
Departures: Oct 2026 to Oct 2027
Trip Styles: Coach, Small Group, Cruise, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
From (Per Person)
A$15,795
Per Person
View Trip
7 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operator: Globus
Departures: Oct 2026 to Mar 2028
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,450
Save 276
Per Person
View Trip
18 Day Spirit of Peru with Amazon and Galápagos Cruises with APT
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operator: APT
Ships: Delfin III
Departures: Jul 2027 to Sep 2028
Trip Styles: Small Group, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
Suite
$27,527
From (Per Person)
A$29,977
Save 2,018
Per Person
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Quito
Operator: Silversea
Ship: Silver Origin
Departures: Apr 2028 to Mar 2029
Visits: Ecuador, Galapagos
Exclusive Savings
Balcony
$18,620
Suite
$22,050
From (Per Person)
A$18,620
Save 583
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operator: Exodus
Departures: Oct 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Ecuador, Galapagos
Exclusive Savings
From (Per Person)
A$8,085
Save 1,720
Per Person
View Trip
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