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South America Cruises Starting In May 2027 and 2028

Are you planning a cruise around South America in May 2027 or 2028? Choose from 50 unique expeditions and cruises with 1,128 departures operated by South America's leading cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the South America cruise that best matches your travel style, budget and dates.
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50 Cruises (1,128 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
A$19,765
Save 446
Per Person
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$9,406
Save 1,922
Per Person
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,864
Save 2,093
Per Person
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$12,772
Save 2,627
Per Person
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,738
Save 3,403
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
A$16,790
Save 1,051
Per Person
View Trip
7 Day Galapagos Adventure: Northern Islands (Grand Daphne) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,001
Save 2,156
Per Person
View Trip
8 Day Galápagos - West & Central Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,487
Save 1,546
Per Person
View Trip
29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Chile, Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
A$18,861
Save 1,092
Per Person
View Trip
11 Day Galápagos Islands - Nine of the Best Isles (Western & Northern Route) with HX Expeditions
Cruise

11 Days (10 Nights) Quito to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Jul 2026 to Mar 2028
Visit: Ecuador, Galapagos
Inside
-
Oceanview
$14,112
Balcony
-
Suite
$18,986
From
A$14,112
Per Person
View Trip
18 Day Spirit of Peru with Amazon and Galápagos Cruises with APT
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operated By: APT
Ships: Delfin III
Departures: Jul 2027 to Sep 2028
Visit: Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$27,527
From
A$29,977
Save 2,018
Per Person
View Trip
31 Day Best of South America with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

31 Days Rio de Janeiro to Guayaquil
Operated By: APT
Departures: May 2027 to Oct 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$42,257
Save 3,126
Per Person
View Trip
17 Day Complete Galápagos - Yolita with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$15,193
Save 4,186
Per Person
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,094
Save 3,830
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,775
Save 1,652
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Quito
Operated By: Tauck
Ship: Silver Origin
Departures: Apr 2027 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
A$27,290
Per Person
View Trip
10 Day Classic Galapagos: Central Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$8,122
Save 2,973
Per Person
View Trip
20 Day Spirit of Peru with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

20 Days Lima to Guayaquil
Operated By: APT
Departures: May 2027 to Oct 2028
Visit: Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$29,466
Save 2,085
Per Person
View Trip
8 Day Pure Galapagos (Grand Daphne) with Intrepid Travel
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: Intrepid Travel
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$6,788
Save 2,968
Per Person
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$5,048
Save 1,434
Per Person
View Trip
15 Day Spirit of Peru with Galápagos Cruise with APT
New ReleaseTour + Cruise

15 Days Lima to Guayaquil
Operated By: APT
Departures: May 2027 to Nov 2028
Visit: Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$20,642
Save 1,889
Per Person
View Trip
8 Day Galápagos - South & East Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$4,801
Save 2,248
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Aug 2026 to Mar 2028
Visit: Ecuador, Galapagos
Last Minute Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,651
Suite
$27,538
From
A$14,651
Save 7,096
Per Person
View Trip
9 Day Island Hopping in the Galapagos with Exodus Tours
New ReleaseCruise

9 Days (8 Nights) Quito to Quito
Operated By: Exodus Tours
Departures: Oct 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,935
Save 672
Per Person
View Trip
26 Day Best of South America with Galápagos Cruise with APT
New ReleaseTour + Cruise

26 Days Rio de Janeiro to Guayaquil
Operated By: APT
Departures: Apr 2027 to Nov 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Early Booking Savings
Exclusive Savings
From
A$33,435
Save 2,118
Per Person
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$13,408
Save 339
Per Person
View Trip
16 Day Galápagos Islands - Nine of the Best Isles plus Machu Picchu with HX Expeditions
Cruise

16 Days (15 Nights) Lima to Quito
Cruise Line: HX Expeditions
Ship: MS Santa Cruz II
Departures: Aug 2026 to Mar 2028
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
$19,859
Balcony
-
Suite
$25,471
From
A$19,859
Per Person
View Trip
15 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

15 Days Lima to Quito
Operated By: Collette
Departures: Aug 2026 to May 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$15,046
Save 605
Per Person
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Ecuador, Galapagos
Exclusive Savings
From
A$7,196
Save 2,043
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
A$13,327
Save 300
Per Person
View Trip
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