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Cruises from Rome

Choose from 436 unique cruises starting in Rome, and traveling to Amalfi, Athens, Barcelona, Bari, Berlin and more. October is the most popular month to join a cruise from Rome and you can select from 1,147 departures available from twenty-two leading cruise lines.
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436 Cruises (1,147 Cruise Departures)
15 Day Harbors Of Heritage with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,349
Suite
$17,599
From
US$17,349
Save 17,349
Per Person
View Trip
9 Day Knights & Sunsets with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,499
Suite
$9,699
From
US$8,499
Save 8,499
Per Person
View Trip
29 Day Hidden Harbors Of France, Spain, Italy & Greece with Seabourn
Cruise

29 Days (28 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 03 June 2028
Visit: Italy, France, Spain, Sardinia (+7 more), Corsica, Monaco, Sicily, Malta, Montenegro, Croatia, Greece
Inside
-
Oceanview
-
Balcony
$21,499
Suite
$34,199
From
US$21,499
Per Person
View Trip
16 Day An Extended Journey Of Spectacular Serenity, Mountain Views & Mythical Spirit with Explora Journeys
Cruise

16 Days (15 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jul 2026 to Sep 2026
Visit: Italy, Corsica, France, Spain, Tunisia, Malta, Sicily
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$10,000
From
US$10,000
Per Person
View Trip
15 Day Italy, Monaco, France & Spain with Seabourn
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain, Corsica, Sardinia
Yours to Explore
Inside
-
Oceanview
-
Balcony
$14,399
Suite
$23,999
From
US$14,399
Per Person
View Trip
8 Day Italian & Aegean Sampler with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2026
Visit: Italy, Sicily, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,799
Suite
-
From
US$4,799
Save 4,799
Per Person
View Trip
10 Day Latin Languages Of Love with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 March 2028
Visit: Italy, Sicily, Sardinia, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$6,199
From
US$3,599
Save 3,599
Per Person
View Trip
10 Day Mediterranean Rivieras: Rome to Barcelona with Scenic
New ReleaseCruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 04 October 2028
Visit: Italy, Corsica, Monaco, France, Spain
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,573
Suite
$14,668
From
US$12,573
Save 2,172
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Rome to New York
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 31 October 2027
Visit: Italy, Spain, Portugal, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$1,187
Oceanview
$1,459
Balcony
$1,755
Suite
$3,866
From
US$1,187
Save 581
Per Person
View Trip
12 Day Greece & Italy Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 18 October 2027
Visit: Italy, Sicily, Greece, Turkey
Exclusive Savings
Inside
$2,640
Oceanview
$3,087
Balcony
$3,446
Suite
$7,857
From
US$2,640
Save 1,550
Per Person
View Trip
12 Day Greece, Turkey & Italy Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: May 2026 to Sep 2027
Visit: Italy, Greece, Turkey
Exclusive Savings
Inside
$1,659
Oceanview
$1,810
Balcony
$2,226
Suite
$4,468
From
US$1,659
Save 1,677
Per Person
View Trip
12 Day Idyllic Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 13 September 2028
Visit: Italy, Sardinia, Corsica, Spain
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,424
Suite
$17,985
From
US$15,424
Save 2,321
Per Person
View Trip
16 Day Spain & Morocco Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Rome to San Juan
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 02 November 2026
Visit: Italy, Spain, Morocco, Saint Martin, Puerto Rico
Exclusive Savings
Inside
$1,394
Oceanview
$1,355
Balcony
-
Suite
-
From
US$1,355
Save 815
Per Person
View Trip
10 Day Circle Italy with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Trieste
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 16 October 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,949
Suite
$11,299
From
US$10,949
Save 10,949
Per Person
View Trip
11 Day Italy's Islands, Corsica to Monaco with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Rome to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 06 October 2027
Visit: Italy, Sicily, Malta, Sardinia, Corsica, Monaco, France
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$7,399
Balcony
-
Suite
$10,189
From
US$7,399
Save 1,796
Per Person
View Trip
11 Day Old World Exploration with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 01 November 2026
Visit: Italy, Malta, Tunisia, Sicily, France, Spain
Exclusive Savings
Inside
-
Oceanview
$8,599
Balcony
$9,599
Suite
$10,249
From
US$8,599
Save 8,599
Per Person
View Trip
23 Day Ultimate Cultures & Wonders of Europe: Italy to Ireland with Scenic
New ReleaseCruise

23 Days (22 Nights) Rome to Dublin
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visit: Italy, Sicily, Malta, Tunisia (+5 more), Algeria, Spain, Portugal, France, Ireland
Inside
-
Oceanview
-
Balcony
$33,920
Suite
$46,570
From
US$33,920
Per Person
View Trip
9 Day Monaco, Italy, France & Spain with Seabourn
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 June 2027
Visit: Italy, Monaco, France, Spain
Yours to Explore
Inside
-
Oceanview
-
Balcony
$6,999
Suite
$11,299
From
US$6,999
Per Person
View Trip
8 Day European Yearnings with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 02 July 2027
Visit: Italy, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,249
Suite
$5,049
From
US$3,249
Save 3,249
Per Person
View Trip
11 Day Spanish Sapphire Shores with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 24 March 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,299
Suite
$11,649
From
US$10,299
Save 10,299
Per Person
View Trip
10 Day In Bloom Around The Boot with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 14 May 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,699
Suite
$6,649
From
US$4,699
Save 4,699
Per Person
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$4,950
Balcony
$5,350
Suite
$8,950
From
US$4,950
Per Person
View Trip
22 Day Exploring Italy, Malta, Greece & Evening At Ephesus with Seabourn
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$14,899
Suite
$24,299
From
US$14,899
Per Person
View Trip
9 Day Dalmatian Rhapsody with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 May 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,099
Suite
$10,699
From
US$10,099
Save 10,099
Per Person
View Trip
15 Day An Extended Journey Through Antique Treasures, Mediterranean Flavours & Island Calm with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visit: Italy, Monaco, France, Spain, Sardinia, Corsica
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$10,640
From
US$10,640
Per Person
View Trip
8 Day Riviera Radiance with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 October 2027
Visit: Italy, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,249
Suite
$4,699
From
US$3,249
Save 3,249
Per Person
View Trip
8 Day A Journey To Italian Hidden Gems & The Heartbeat Of Catalan Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 May 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,000
From
US$5,000
Per Person
View Trip
14 Day Mediterranean with MSC Cruises
Cruise

14 Days (13 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 14 April 2027
Visit: Italy, Spain, France, Morocco, Portugal
Inside
$1,608
Oceanview
$1,867
Balcony
-
Suite
$2,866
From
US$1,608
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 July 2026
Visit: Italy, Monaco, France, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,935
From
US$5,935
Per Person
View Trip
15 Day Mediterranean Collage with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 07 August 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,749
Suite
$11,399
From
US$8,749
Save 8,749
Per Person
View Trip
Results: 361-390 of 436

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