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Italy Cruises Starting In May 2026

If you're looking at joining a cruise to Italy in May 2026, we have 65 unique cruise itineraries and 1,206 departures available, operated by eighteen of the world's leading cruise lines departing in May.
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Departures (May 2026)
< April 2026 June 2026 >
Duration
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15 Days
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$79,580pp
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65 Cruises (1,206 Cruise Departures)
8 Day Amalfi Coast Sailing Adventure with Intrepid Travel
Cruise

8 Days (7 Nights) Procida to Procida
Operated By: Intrepid Travel
Departures: Aug 2025 to Oct 2026
Countries Visited: Italy
Exclusive Deal
Save
1,018
From
2,468
per person
View Trip
6 Day Côte d'Azur & Beyond with Emerald Cruises
New ReleaseCruise

6 Days (5 Nights) Nice to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 21 May 2026
Countries Visited: France, Italy, Monaco
Mutiple Deals Available
Inside
-
Oceanview
$4,880
Balcony
-
Suite
$6,322
Save
4,910
From
4,880
per person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Trieste to Athens
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 03 May 2026
Countries Visited: Italy, Greece
One Way Cruise Offer
Inside
$279
Oceanview
$349
Balcony
$409
Suite
$629
From
279
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: May 2026 to Oct 2027
Countries Visited: Greece, Italy
Escape To Sea
Inside
$907
Oceanview
$1,117
Balcony
$1,537
Suite
$1,767
From
907
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: May 2026 to Oct 2027
Countries Visited: Italy, Greece
Escape To Sea
Inside
$908
Oceanview
$1,118
Balcony
$1,538
Suite
$1,768
From
908
per person
View Trip
8 Day The French Riviera Under Le Ponant’s Sails with Ponant
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 07 May 2026
Countries Visited: France, Italy
Inside
-
Oceanview
$13,060
Balcony
$17,550
Suite
$20,110
From
13,060
per person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Magnifica, MSC Opera
Departures: Oct 2025 to May 2026
Countries Visited: Italy, France
One Way Cruise Offer
Inside
$69
Oceanview
$119
Balcony
$169
Suite
$329
From
69
per person
View Trip
8 Day Greek Isles Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: Aug 2025 to Oct 2026
Countries Visited: Italy, Greece, Turkey
Latest OfferExclusive Solo Offer
Inside
$1,069
Oceanview
$1,219
Balcony
$1,271
Suite
$2,057
Save
1,285
From
1,069
per person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+10 more), Viking Libra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Sep 2025 to Sep 2028
Countries Visited: Italy, Monaco, France, Spain
Mutiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,799
Save
1,750
From
2,599
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: Aug 2025 to Oct 2026
Countries Visited: Italy, Spain, France
Escape To Sea
Inside
$981
Oceanview
$1,121
Balcony
$1,261
Suite
$1,970
From
981
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Aug 2025 to Oct 2026
Countries Visited: Spain, Italy, France
Escape To Sea
Inside
$804
Oceanview
$989
Balcony
$1,041
Suite
$1,531
From
804
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Aug 2025 to Oct 2026
Countries Visited: France, Spain, Italy
Escape To Sea
Inside
$801
Oceanview
$921
Balcony
$1,023
Suite
$1,757
From
801
per person
View Trip
10 Day Mediterranean with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Sep 2026
Countries Visited: Italy, Greece, Turkey
Escape To Sea
Inside
$1,126
Oceanview
$1,234
Balcony
$1,360
Suite
$1,918
From
1,126
per person
View Trip
15 Day Gardens of the Italian Lakes, Slovenia & Croatian Islands Cruise with APT
Tour + Cruise

15 Days Milan to Dubrovnik
Operated By: APT
Ship: MV Lady Eleganza
Departure: 26 May 2026
Trip Styles: Coach, Cruise, Gardens, Island Hopping, Scenic
Countries Visited: Italy, Slovenia, Croatia
Inside
-
Oceanview
$11,045
Balcony
-
Suite
-
From
11,045
per person
View Trip
10 Day Adriatic & Aegean Gems with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Aug 2025 to Nov 2026
Countries Visited: Greece, Turkey, Italy
Book Early Offer + Onboard CreditEscape To Sea
Inside
$1,227
Oceanview
$1,357
Balcony
$1,467
Suite
$2,047
From
1,227
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Amalfi to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Apr 2026 to Oct 2027
Countries Visited: Italy, Greece, Turkey
Book Early Offer + Onboard CreditEscape To Sea
Inside
$991
Oceanview
$1,161
Balcony
$1,301
Suite
$1,741
From
991
per person
View Trip
12 Day Sicily, the Amalfi Coast & Rome with Tauck
Cruise

12 Days (11 Nights) Malta to Rome
Operated By: Tauck
Departures: Apr 2026 to Oct 2026
Countries Visited: Malta, Sicily, Italy
From
12,490
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Cannes to Cannes
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: Aug 2025 to Oct 2026
Countries Visited: France, Italy, Spain
Escape To Sea
Inside
$1,018
Oceanview
$1,158
Balcony
$1,298
Suite
$2,143
From
1,018
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Apr 2026 to Oct 2027
Countries Visited: Italy, Montenegro, Greece
Escape To Sea
Inside
$992
Oceanview
$1,182
Balcony
$1,602
Suite
$1,842
From
992
per person
View Trip
8 Day Greek Isles Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departures: Sep 2025 to Sep 2026
Countries Visited: Italy, Greece, Croatia
Latest Offer
Inside
$919
Oceanview
$1,201
Balcony
$1,443
Suite
$1,790
Save
732
From
919
per person
View Trip
10 Day Europe - Greek Isles & Adriatic with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Trieste to Trieste
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Aug 2025 to Nov 2026
Countries Visited: Italy, Greece, Turkey
Escape To SeaBook Early Offer + Onboard Credit + WiFi
Inside
$1,271
Oceanview
$1,401
Balcony
$1,511
Suite
$2,231
From
1,271
per person
View Trip
8 Day Hidden Gems of the Croatian Riviera with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Dubrovnik to Venice
Cruise Line: Emerald Cruises
Ships: Emerald Kaia, Emerald Azzurra
Departures: Aug 2025 to Sep 2026
Countries Visited: Croatia, Slovenia, Italy
Mutiple Deals Available
Inside
-
Oceanview
$6,331
Balcony
-
Suite
$8,459
Save
20,296
From
6,331
per person
View Trip
10 Day Mediterranean with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Sep 2026
Countries Visited: Greece, Turkey, Italy
Escape To Sea
Inside
$1,287
Oceanview
$1,417
Balcony
$1,527
Suite
$2,107
From
1,287
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Aug 2025 to Oct 2026
Countries Visited: Italy, France, Spain
Escape To Sea
Inside
$796
Oceanview
$916
Balcony
$1,062
Suite
$1,532
From
796
per person
View Trip
10 Day Mediterranean with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Trieste to Trieste
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: May 2026 to Sep 2026
Countries Visited: Italy, Greece, Turkey
Escape To Sea
Inside
$1,301
Oceanview
$1,441
Balcony
$1,531
Suite
$2,251
From
1,301
per person
View Trip
8 Day Yachting Havens with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 May 2026
Countries Visited: Spain, France, Italy
Summer Of ChoiceExclusive Deal
Inside
$1,980
Oceanview
$2,070
Balcony
$2,385
Suite
$3,645
From
1,980
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: Aug 2025 to Oct 2026
Countries Visited: Spain, France, Italy
Escape To Sea
Inside
$989
Oceanview
$1,129
Balcony
$1,269
Suite
$1,989
From
989
per person
View Trip
8 Day A Journey Of Lush Landscapes & Golden Enchantment with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Athens to Venice
Cruise Line: Explora Journeys
Ship: Explora II
Departures: May 2026 to Oct 2026
Countries Visited: Greece, Croatia, Italy
Unique Summer Special
Inside
-
Oceanview
-
Balcony
$4,920
Suite
$5,680
From
4,920
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Apr 2026 to Oct 2027
Countries Visited: Italy, Greece, Turkey
Book Early Offer + Onboard CreditEscape To Sea
Inside
$987
Oceanview
$1,157
Balcony
$1,297
Suite
$1,737
From
987
per person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (4)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+8 more), Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Oct 2025 to Sep 2028
Countries Visited: Italy, Croatia, Sicily
Mutiple Deals Available
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,499
Save
1,100
From
3,599
per person
View Trip
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