Home > Cruises > Europe Cruises > Mediterranean Cruises > Italy > April

Italy Cruises Starting In April 2027 and 2028

If you're looking at joining a cruise to Italy in April 2027 or 2028, we have 259 unique cruise itineraries and 3,602 departures available, operated by twenty-one of the world's leading cruise lines departing in April.
Filter Results
Departures
Duration
3 Days
23 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$200pp
$100,750pp
Countries
Show More...
Filter Results
259 Cruises (3,602 Cruise Departures)
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$679
Oceanview
$798
Balcony
$936
Suite
$2,033
From
A$679
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: May 2026 to Oct 2027
Visit: Greece, Italy
Easter Flash Sale
Exclusive Savings
Inside
$999
Oceanview
$1,455
Balcony
$1,999
Suite
$2,594
From
A$999
Save 18
Per Person
View Trip
6 Day A Journey From Ancient Whispers To Aegean Wonders with Explora Journeys
Cruise
 (1)

6 Days (5 Nights) Rome to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 April 2026
Visit: Italy, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$5,081
From
A$5,081
Save 104
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$354
Oceanview
$453
Balcony
$552
Suite
$1,047
From
A$354
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Florence to Valencia
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 22 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$708
Suite
-
From
A$708
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Exclusive Savings
Inside
$449
Oceanview
-
Balcony
$786
Suite
$1,439
From
A$449
Per Person
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 20 April 2026
Visit: Italy, France
Exclusive Savings
Inside
-
Oceanview
$423
Balcony
$552
Suite
-
From
A$423
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece
Easter Flash Sale
Exclusive Savings
Inside
$891
Oceanview
$1,356
Balcony
$1,782
Suite
$2,158
From
A$891
Save 20
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 20 April 2026
Visit: France, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$867
Suite
-
From
A$867
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 21 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$538
Oceanview
-
Balcony
$885
Suite
$1,548
From
A$538
Per Person
View Trip
5 Day A Journey Through Riviera Elegance & Coastal Splendour with Explora Journeys
Cruise
 (1)

5 Days (4 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$4,234
From
A$4,234
Save 86
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 23 April 2026
Visit: Italy, Spain
Easter Flash Sale
Exclusive Savings
Inside
-
Oceanview
$636
Balcony
$844
Suite
$1,557
From
A$636
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Venice to Brindisi
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 April 2027
Visit: Italy, Montenegro
Exclusive Savings
Inside
$609
Oceanview
$708
Balcony
$996
Suite
$1,174
From
A$609
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Italy, Spain, France
Easter Flash Sale
Exclusive Savings
Inside
$831
Oceanview
$1,009
Balcony
$1,257
Suite
$2,108
From
A$831
Save 21
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Apr 2028
Visit: Greece, Turkey, Italy
Easter Flash Sale
Exclusive Savings
Inside
$831
Oceanview
$1,059
Balcony
$1,485
Suite
$1,999
From
A$831
Save 21
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Apr 2026
Visit: Italy, Spain, France
Easter Flash Sale
Exclusive Savings
Inside
$821
Oceanview
$970
Balcony
$1,346
Suite
-
From
A$821
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Spain, France, Italy
Easter Flash Sale
Exclusive Savings
Inside
$693
Oceanview
$1,069
Balcony
$1,316
Suite
$2,138
From
A$693
Save 21
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Istanbul to Istanbul
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Apr 2028
Visit: Turkey, Greece, Italy
Easter Flash Sale
Exclusive Savings
Inside
$831
Oceanview
$1,059
Balcony
$1,485
Suite
$1,999
From
A$831
Save 21
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,964
Suite
$6,414
From
A$3,964
Save 1,403
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,944
Suite
$8,864
From
A$4,944
Save 1,419
Per Person
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Nice
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Sakara
Departures: Apr 2026 to Jul 2027
Visit: Italy, Corsica, Monaco, France
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
$8,695
Balcony
-
Suite
$9,967
From
A$9,967
Save 2,178
Per Person
View Trip
6 Day Greece & Adriatic Sampler with Princess
Cruise
 (1)

6 Days (5 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 10 April 2026
Visit: Italy, Montenegro, Greece
Princess Standard
Exclusive Savings
Inside
$843
Oceanview
-
Balcony
$1,130
Suite
$1,850
From
A$843
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Marseille to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 22 April 2026
Visit: France, Italy, Spain
Exclusive Savings
Inside
$963
Oceanview
$1,101
Balcony
$1,200
Suite
$1,982
From
A$963
Per Person
View Trip
9 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santa Cruz De Tenerife to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 12 April 2026
Visit: Spain, Morocco, Italy
Exclusive Savings
Inside
-
Oceanview
$988
Balcony
$1,206
Suite
-
From
A$988
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2026 to Apr 2026
Visit: Italy, Spain, France
Easter Flash Sale
Exclusive Savings
Inside
$695
Oceanview
$814
Balcony
$893
Suite
$1,695
From
A$695
Save 16
Per Person
View Trip
9 Day Italy Intensive Cruise: Portofino, Florence & Porto Santo Stefano with Azamara Cruises
Cruise
 (3)

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 09 April 2026
Visit: Spain, France, Italy
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$2,468
Balcony
-
Suite
-
From
A$2,468
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy
Exclusive Savings
Inside
$1,980
Oceanview
$2,286
Balcony
$2,445
Suite
$3,606
From
A$1,980
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 20 April 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
$560
Balcony
$788
Suite
$1,283
From
A$560
Per Person
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Lanzarote to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 13 April 2026
Visit: Spain, Morocco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,683
Suite
-
From
A$1,683
Per Person
View Trip
8 Day Authentic Mediterranean Shores with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2027 to May 2027
Visit: Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,174
Suite
$13,499
From
A$7,174
Save 220
Per Person
View Trip
Results: 1-30 of 259

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Music Themed Cruises Short Break Cruises

Trip Lengths

1 Month 10 Day 2 Week 3 Day 3 Week 7 Day

Departure Months

April May June July August September October November December January February March

Cities

Amalfi Bari Bologna Florence Genoa Naples Rome Trieste Venice

Routes

Athens to Bologna Athens to Rome Athens to Venice Barcelona to Trieste Barcelona to Rome Barcelona to Venice Barcelona to Bologna Bari to Bari Bologna to Rome Genoa to Genoa Istanbul to Rome Lisbon to Rome Miami to Rome Rome to Trieste Rome to Lisbon Rome to Bologna Rome to Athens Rome to Barcelona Rome to Venice Rome to Monte Carlo Rome to Fort Lauderdale Rome to Istanbul Rome to Rome Trieste to Barcelona Trieste to Rome Trieste to Trieste Trieste to Athens Venice to Venice Venice to Athens Venice to Barcelona Venice to Rome Venice to Istanbul

Country Routes

Brazil to Italy Croatia to Italy France to Italy Greece to Italy Italy to Croatia Italy to Brazil Italy to France Italy to Greece Italy to Monaco Italy to Portugal Italy to Spain Italy to Turkey Italy to USA Italy to Malta Malta to Italy Portugal to Italy Spain to Italy Turkey to Italy United Arab Emirates to Italy USA to Italy

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises P&O (UK) Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2026. Global Journeys. You're viewing our site in Australian dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations