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Patagonia Cruises Starting In January 2027 and 2028

Are you planning a cruise exploring Patagonia in January 2027 or 2028? Choose from 27 unique expeditions and cruises with 49 departures operated by Patagonia's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Patagonia cruise that best matches your travel style, budget and dates.
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27 Cruises (49 Cruise Departures)
29 Day Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 30 January 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Fly Free Premium Economy
Fly Free Business Class
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$45,565
Suite
$51,167
From
US$45,565
Save 23,805
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$38,983
Suite
$39,735
From
US$38,983
Save 23,622
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (6)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$8,099
Suite
$12,999
From
US$8,099
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
$3,174
Oceanview
$3,717
Balcony
$4,551
Suite
$6,976
From
US$3,174
Save 75
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$5,642
Oceanview
$6,210
Balcony
$8,610
Suite
$11,317
From
US$5,642
Save 7,156
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (6)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$12,999
From
US$8,299
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$4,305
Oceanview
$4,693
Balcony
$6,148
Suite
$8,670
From
US$4,305
Save 4,493
Per Person
View Trip
22 Day Lima (Callao) to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 January 2028
Visit: Peru, Chile, Argentina, Falkland Islands
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,600
Suite
$28,400
From
US$15,600
Save 8,400
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Mar 2026 to Mar 2027
Visit: Argentina, Chile
Exclusive Savings
From
US$9,814
Save 889
Per Person
View Trip
18 Day Valparaiso to Buenos Aires with Silversea
Cruise

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 29 January 2028
Visit: Chile, Argentina, Falkland Islands
All-Inclusive Fare
Inside
-
Oceanview
$13,800
Balcony
$15,500
Suite
-
From
US$13,800
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Valparaiso
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 January 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$6,308
Oceanview
$6,647
Balcony
$9,412
Suite
$13,146
From
US$6,308
Save 6,590
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (2)

23 Days (22 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 10 January 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Fare Saver
Exclusive Savings
Inside
$4,673
Oceanview
$4,869
Balcony
$7,466
Suite
$9,328
From
US$4,673
Save 71
Per Person
View Trip
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+5 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Savings
Inside
-
Oceanview
$37,371
Balcony
$42,271
Suite
-
From
US$37,371
Save 628
Per Person
View Trip
42 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

42 Days (41 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Advantage Fare
Exclusive Savings
Inside
$10,137
Oceanview
$11,264
Balcony
$19,839
Suite
-
From
US$10,137
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$20,133
Oceanview
$20,958
Balcony
$27,408
Suite
$38,466
From
US$20,133
Save 20,965
Per Person
View Trip
50 Day Valparaiso To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (4)

50 Days (49 Nights) Valparaiso to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+5 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$17,404
Oceanview
$18,665
Balcony
$22,545
Suite
$34,214
From
US$17,404
Save 415
Per Person
View Trip
71 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

71 Days (70 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+12 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Barbados, Saint Lucia, Saint Kitts and Nevis, Puerto Rico
Advantage Fare
Exclusive Savings
Inside
$15,385
Oceanview
$17,149
Balcony
$30,477
Suite
$60,857
From
US$15,385
Per Person
View Trip
83 Day South America, Antarctica, South Atlantic & Africa with Seabourn
Cruise
 (1)

83 Days (82 Nights) Miami to Cape Town
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+8 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique
Exclusive Savings
Inside
-
Oceanview
$54,079
Balcony
$60,939
Suite
-
From
US$54,079
Save 920
Per Person
View Trip
69 Day Miami To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (4)

69 Days (68 Nights) Miami to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+13 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$22,787
Oceanview
$26,511
Balcony
$31,943
Suite
$46,028
From
US$22,787
Save 522
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (4)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Exclusive Savings
Inside
$25,403
Oceanview
$29,613
Balcony
$35,821
Suite
$51,826
From
US$25,403
Save 586
Per Person
View Trip
75 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (3)

75 Days (74 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+18 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Peru, Panama, Costa Rica, Colombia, Mexico
Azamara Always Included
Exclusive Savings
Inside
$28,068
Oceanview
$29,261
Balcony
$32,763
Suite
$53,443
From
US$28,068
Save 661
Per Person
View Trip
66 Day Grand South America Mosaic with Regent Seven Seas
Cruise

66 Days (65 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 13 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Costa Rica, Panama, Ecuador, Peru, Chile, Antarctica, Falkland Islands, Argentina, Uruguay, Brazil, Saint Lucia, Saint Kitts and Nevis
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$51,303
Suite
$53,263
From
US$51,303
Save 83,095
Per Person
View Trip
113 Day Cape To Cape World Cruise: Miami To Lisbon with Seabourn
Cruise
 (1)

113 Days (112 Nights) Miami to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+18 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
$71,586
Balcony
$80,406
Suite
$152,142
From
US$71,586
Save 1,213
Per Person
View Trip
121 Day Cape To Cape World Cruise: Miami To Dover with Seabourn
Cruise
 (1)

121 Days (120 Nights) Miami to London
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+20 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Exclusive Savings
Inside
-
Oceanview
$76,702
Balcony
$87,482
Suite
$192,342
From
US$76,702
Save 1,297
Per Person
View Trip
122 Day MSC World Cruise with MSC Cruises
Cruise

122 Days (121 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 06 January 2027
Visit: France, Spain, Gibraltar, Morocco (+20 more), Cape Verde, Brazil, Argentina, Falkland Islands, Chile, French Polynesia, Cook Islands, New Zealand, Australia, New Caledonia, Vanuatu, American Samoa, USA, Mexico, Costa Rica, Panama, Jamaica, Virgin Islands, Saint Martin, Italy
Exclusive Savings
Inside
$16,622
Oceanview
$19,493
Balcony
$28,272
Suite
-
From
US$16,622
Save 427
Per Person
View Trip
122 Day MSC World Cruise with MSC Cruises
Cruise

122 Days (121 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 04 January 2027
Visit: Italy, France, Spain, Gibraltar (+20 more), Morocco, Cape Verde, Brazil, Argentina, Falkland Islands, Chile, French Polynesia, Cook Islands, New Zealand, Australia, New Caledonia, Vanuatu, American Samoa, USA, Mexico, Costa Rica, Panama, Jamaica, Virgin Islands, Saint Martin
Exclusive Savings
Inside
-
Oceanview
$19,493
Balcony
$28,272
Suite
-
From
US$19,493
Save 516
Per Person
View Trip
122 Day MSC World Cruise with MSC Cruises
Cruise

122 Days (121 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 05 January 2027
Visit: Italy, France, Spain, Gibraltar (+20 more), Morocco, Cape Verde, Brazil, Argentina, Falkland Islands, Chile, French Polynesia, Cook Islands, New Zealand, Australia, New Caledonia, Vanuatu, American Samoa, USA, Mexico, Costa Rica, Panama, Jamaica, Virgin Islands, Saint Martin
Exclusive Savings
Inside
$16,622
Oceanview
$19,493
Balcony
$28,272
Suite
$73,949
From
US$16,622
Save 427
Per Person
View Trip
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