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Patagonia Cruises Starting In January 2027 and 2028

Are you planning a cruise exploring Patagonia in January 2027 or 2028? Choose from 33 unique expeditions and cruises with 56 departures operated by Patagonia's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Patagonia cruise that best matches your travel style, budget and dates.
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122 Days
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33 Cruises (56 Cruise Departures)
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$39,185
Suite
$47,435
From
US$39,185
Per Person
View Trip
29 Day Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse I
Departures: Jan 2027 to Feb 2028
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$45,813
Suite
$53,387
From
US$58,194
Save 6,226
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (7)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$12,999
From
US$8,299
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (7)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$8,099
Suite
$12,999
From
US$8,099
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$4,549
Oceanview
$4,799
Balcony
$6,299
Suite
$8,899
From
US$4,549
Save 4,549
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$5,567
Oceanview
$5,992
Balcony
-
Suite
$22,499
From
US$5,567
Save 7,531
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2026 to Mar 2027
Visit: Argentina, Chile
From
US$10,199
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Inside
$3,249
Oceanview
$3,809
Balcony
$4,669
Suite
$7,169
From
US$3,249
Per Person
View Trip
57 Day South America Discovery From Fort Lauderdale with Cunard
Cruise

57 Days (56 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil (+7 more), Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba
Bonus Onboard Credit
Inside
$11,099
Oceanview
$14,809
Balcony
$15,499
Suite
$35,199
From
US$11,099
Per Person
View Trip
22 Day Lima (Callao) to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 January 2028
Visit: Peru, Chile, Argentina, Falkland Islands
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,800
Suite
$28,000
From
US$16,800
Save 3,500
Per Person
View Trip
18 Day Valparaiso to Buenos Aires with Silversea
Cruise

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 29 January 2028
Visit: Chile, Argentina, Falkland Islands
All-Inclusive Fare
Inside
-
Oceanview
$13,800
Balcony
$16,200
Suite
$42,500
From
US$13,800
Per Person
View Trip
38 Day Fort Lauderdale To San Antonio with Cunard
Cruise

38 Days (37 Nights) Fort Lauderdale to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil, Uruguay, Argentina, Chile
Bonus Onboard Credit
Inside
$7,398
Oceanview
$10,233
Balcony
$11,230
Suite
$24,780
From
US$7,398
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 10 January 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Fare Saver
Inside
$4,899
Oceanview
-
Balcony
$7,599
Suite
$12,799
From
US$4,899
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Feb 2027 to Jan 2028
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Fare Saver
Book Early & Have It All Fare Option
Inside
$4,509
Oceanview
$5,009
Balcony
$6,509
Suite
$8,759
From
US$4,509
Per Person
View Trip
50 Day Valparaiso To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (5)

50 Days (49 Nights) Valparaiso to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+5 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$17,819
Oceanview
$19,119
Balcony
$23,119
Suite
$35,149
From
US$17,819
Per Person
View Trip
42 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

42 Days (41 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Advantage Fare
Inside
$10,284
Oceanview
$11,434
Balcony
$20,184
Suite
$40,134
From
US$10,284
Per Person
View Trip
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+5 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Yours to Explore
Inside
-
Oceanview
$37,999
Balcony
$42,999
Suite
-
From
US$37,999
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$20,849
Oceanview
$21,499
Balcony
$28,649
Suite
-
From
US$20,849
Save 20,849
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Valparaiso
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 January 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,599
Oceanview
$6,799
Balcony
$9,899
Suite
-
From
US$6,599
Save 6,599
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 08 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Book Early & Have It All Fare Option
Inside
$4,659
Oceanview
$5,159
Balcony
$7,109
Suite
$9,759
From
US$4,659
Per Person
View Trip
91 Day South America Discovery with Cunard
Cruise

91 Days (90 Nights) Hamburg to Hamburg
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 January 2027
Visit: Germany, Holland, Belgium, England (+13 more), Bermuda, USA, Turks and Caicos Islands, Barbados, Brazil, Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba, Portugal
Bonus Onboard Credit
Inside
$14,289
Oceanview
$19,779
Balcony
$21,799
Suite
$42,999
From
US$14,289
Per Person
View Trip
83 Day South America Discovery with Cunard
Cruise

83 Days (82 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 10 January 2027
Visit: England, Bermuda, USA, Turks and Caicos Islands (+10 more), Barbados, Brazil, Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba, Portugal
Bonus Onboard Credit
Inside
$13,249
Oceanview
$18,259
Balcony
$20,219
Suite
$40,029
From
US$13,249
Per Person
View Trip
71 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

71 Days (70 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+12 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Barbados, Saint Lucia, Saint Kitts and Nevis, Puerto Rico
Advantage Fare
Inside
$15,614
Oceanview
$17,414
Balcony
$31,014
Suite
$62,014
From
US$15,614
Per Person
View Trip
83 Day South America, Antarctica, South Atlantic & Africa with Seabourn
Cruise
 (1)

83 Days (82 Nights) Miami to Cape Town
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+8 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique
Yours to Explore
Inside
-
Oceanview
$54,999
Balcony
$61,999
Suite
-
From
US$54,999
Per Person
View Trip
69 Day Miami To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (5)

69 Days (68 Nights) Miami to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+13 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$23,309
Oceanview
$27,149
Balcony
$32,749
Suite
$47,269
From
US$23,309
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (5)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Inside
$25,989
Oceanview
$30,329
Balcony
$36,729
Suite
$53,229
From
US$25,989
Per Person
View Trip
75 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (3)

75 Days (74 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+18 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Peru, Panama, Costa Rica, Colombia, Mexico
Azamara Always Included
Inside
$28,729
Oceanview
$29,959
Balcony
$38,099
Suite
$54,889
From
US$28,729
Per Person
View Trip
66 Day Grand South America Mosaic with Regent Seven Seas
Cruise

66 Days (65 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 13 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Costa Rica, Panama, Ecuador, Peru, Chile, Antarctica, Falkland Islands, Argentina, Uruguay, Brazil, Saint Lucia, Saint Kitts and Nevis
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$71,499
From
US$71,499
Save 71,499
Per Person
View Trip
121 Day Cape To Cape World Cruise: Miami To Dover with Seabourn
Cruise
 (1)

121 Days (120 Nights) Miami to London
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+20 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Inside
-
Oceanview
$77,999
Balcony
$94,784
Suite
$195,999
From
US$77,999
Per Person
View Trip
113 Day Cape To Cape World Cruise: Miami To Lisbon with Seabourn
Cruise
 (1)

113 Days (112 Nights) Miami to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+18 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal
Inside
-
Oceanview
$75,274
Balcony
$87,114
Suite
-
From
US$75,274
Per Person
View Trip
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