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Patagonia Cruises Starting In January 2027 and 2028

Are you planning a cruise exploring Patagonia in January 2027 or 2028? Choose from 35 unique expeditions and cruises with 62 departures operated by Patagonia's leading cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Patagonia cruise that best matches your travel style, budget and dates.
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122 Days
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35 Cruises (62 Cruise Departures)
29 Day Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse I
Departures: Feb 2026 to Jan 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Fly Free Premium Economy
Fly Free Business Class
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$43,528
Suite
$48,330
From
US$45,565
Save 23,812
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Feb 2026 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$35,370
Suite
$39,735
From
US$35,370
Save 27,785
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (6)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$8,099
Suite
$12,999
From
US$8,099
Per Person
View Trip
18 Day Valparaiso to Buenos Aires with Silversea
Cruise

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 29 January 2028
Visit: Chile, Argentina, Falkland Islands
All-Inclusive Fare
Inside
-
Oceanview
$13,800
Balcony
$15,500
Suite
-
From
US$13,800
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
$3,174
Oceanview
$3,717
Balcony
$4,551
Suite
$6,976
From
US$3,174
Save 75
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$5,642
Oceanview
$6,079
Balcony
$7,999
Suite
$11,142
From
US$5,642
Save 7,156
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (6)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$7,599
Suite
$12,999
From
US$7,599
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Departure: 19 January 2028
Visit: Peru, Chile
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$4,305
Oceanview
$4,693
Balcony
$6,148
Suite
$8,670
From
US$4,305
Save 4,493
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Feb 2026 to Mar 2027
Visit: Argentina, Chile
New Year Sale
Exclusive Savings
From
US$9,422
Save 885
Per Person
View Trip
22 Day Lima (Callao) to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 January 2028
Visit: Peru, Chile, Argentina, Falkland Islands
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,170
Suite
$28,240
From
US$16,170
Save 6,930
Per Person
View Trip
38 Day Fort Lauderdale To San Antonio with Cunard
Cruise

38 Days (37 Nights) Fort Lauderdale to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil, Uruguay, Argentina, Chile
Exclusive Savings
Inside
$6,788
Oceanview
$10,065
Balcony
$11,570
Suite
$24,193
From
US$6,788
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$20,133
Oceanview
$20,958
Balcony
$27,408
Suite
$38,369
From
US$20,133
Save 20,965
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Valparaiso
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 January 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$6,065
Oceanview
$6,647
Balcony
$8,975
Suite
$13,146
From
US$6,065
Save 6,333
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (2)

23 Days (22 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ship: Oosterdam
Departures: Feb 2027 to Jan 2028
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,355
Oceanview
$4,551
Balcony
$6,472
Suite
$8,314
From
US$4,355
Save 69
Per Person
View Trip
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+5 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Savings
Inside
-
Oceanview
$33,647
Balcony
$38,057
Suite
-
From
US$33,647
Save 552
Per Person
View Trip
24 Day Chile, Antarctica & Falkland Islands Cruise: Chilean Fjords, Ushuaia & Montevideo with Azamara Cruises
Cruise
 (4)

24 Days (23 Nights) Valparaiso to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Exclusive Savings
Inside
$7,187
Oceanview
$8,438
Balcony
$10,340
Suite
$15,878
From
US$7,187
Save 172
Per Person
View Trip
42 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

42 Days (41 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Advantage Fare
Exclusive Savings
Inside
$10,137
Oceanview
$11,264
Balcony
$19,839
Suite
-
From
US$10,137
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (2)

23 Days (22 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jan 2027 to Jan 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,452
Oceanview
$4,648
Balcony
$6,697
Suite
$8,902
From
US$4,452
Save 69
Per Person
View Trip
50 Day Valparaiso To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (4)

50 Days (49 Nights) Valparaiso to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+5 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$17,404
Oceanview
$18,665
Balcony
$22,545
Suite
$34,214
From
US$17,404
Save 415
Per Person
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise
 (2)

25 Days (24 Nights) Rio de Janeiro to Santiago
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Visit: Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,375
Suite
-
From
US$9,375
Save 9,823
Per Person
View Trip
59 Day Valparaiso To Miami Grand Voyage with Azamara Cruises
Cruise
 (4)

59 Days (58 Nights) Valparaiso to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+12 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands, USA
Azamara Always Included
Exclusive Savings
Inside
$19,740
Oceanview
$21,874
Balcony
$26,433
Suite
$40,294
From
US$19,740
Save 469
Per Person
View Trip
71 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

71 Days (70 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+12 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Barbados, Saint Lucia, Saint Kitts and Nevis, Puerto Rico
Advantage Fare
Exclusive Savings
Inside
$15,385
Oceanview
$17,149
Balcony
$30,477
Suite
$60,857
From
US$15,385
Per Person
View Trip
83 Day South America Discovery with Cunard
Cruise

83 Days (82 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 10 January 2027
Visit: England, Bermuda, USA, Turks and Caicos Islands (+10 more), Barbados, Brazil, Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba, Portugal
Exclusive Savings
Inside
$13,068
Oceanview
$18,117
Balcony
$20,058
Suite
$40,016
From
US$13,068
Per Person
View Trip
83 Day South America, Antarctica, South Atlantic & Africa with Seabourn
Cruise
 (1)

83 Days (82 Nights) Miami to Cape Town
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+8 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique
Exclusive Savings
Inside
-
Oceanview
$48,689
Balcony
$54,863
Suite
$100,727
From
US$48,689
Save 810
Per Person
View Trip
57 Day South America Discovery From Fort Lauderdale with Cunard
Cruise

57 Days (56 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil (+7 more), Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba
Exclusive Savings
Inside
$11,069
Oceanview
$15,712
Balcony
$18,345
Suite
$35,175
From
US$11,069
Per Person
View Trip
69 Day Miami To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (4)

69 Days (68 Nights) Miami to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+13 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$22,787
Oceanview
$26,511
Balcony
$31,943
Suite
$46,028
From
US$22,787
Save 522
Per Person
View Trip
43 Day Miami To Buenos Aires Grand Voyage with Azamara Cruises
Cruise
 (4)

43 Days (42 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+9 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Exclusive Savings
Inside
$14,374
Oceanview
$16,217
Balcony
$20,194
Suite
$28,351
From
US$14,374
Save 335
Per Person
View Trip
75 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (3)

75 Days (74 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+18 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Peru, Panama, Costa Rica, Colombia, Mexico
Azamara Always Included
Exclusive Savings
Inside
$26,176
Oceanview
$29,261
Balcony
$32,763
Suite
$85,181
From
US$26,176
Save 603
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (4)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Exclusive Savings
Inside
$25,403
Oceanview
$29,613
Balcony
$35,821
Suite
$51,826
From
US$25,403
Save 586
Per Person
View Trip
66 Day Grand South America Mosaic with Regent Seven Seas
Cruise

66 Days (65 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 13 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Costa Rica, Panama, Ecuador, Peru, Chile, Antarctica, Falkland Islands, Argentina, Uruguay, Brazil, Saint Lucia, Saint Kitts and Nevis
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$49,343
Suite
$52,724
From
US$49,343
Save 81,055
Per Person
View Trip
Results: 1-30 of 35

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