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Patagonia Luxury Cruises

Explore the best luxury cruises exploring Patagonia. Choose from 47 unique cruise itineraries with 42 past traveler reviews from 8 leading cruise lines. February and January are the most popular months to join a luxury cruise exploring Patagonia with 59 departures starting between October 2026 and March 2029.
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121 Days
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47 Cruises (59 Cruise Departures)
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$39,361
Suite
$44,597
From
US$39,361
Save 6,289
Per Person
View Trip
29 Day Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Jan 2027 to Feb 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$41,464
Suite
$44,385
From
US$41,464
Save 6,776
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$41,715
Suite
$47,435
From
US$41,715
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$4,549
Oceanview
$4,799
Balcony
$6,299
Suite
-
From
US$4,549
Save 4,549
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,549
Oceanview
$7,049
Balcony
-
Suite
$13,549
From
US$6,549
Save 6,549
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Inside
$3,249
Oceanview
$3,809
Balcony
$4,669
Suite
$7,169
From
US$3,249
Per Person
View Trip
57 Day South America Discovery From Fort Lauderdale with Cunard
Cruise

57 Days (56 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil (+7 more), Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba
Bonus Onboard Credit
Inside
$11,099
Oceanview
$14,809
Balcony
$15,499
Suite
$35,199
From
US$11,099
Per Person
View Trip
27 Day Treasures of South America: Chilean Fjords to the Iguazu falls - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Chile, Brazil
Inside
-
Oceanview
-
Balcony
$36,115
Suite
$83,955
From
US$36,115
Per Person
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visit: Peru, Chile, Argentina
Inside
-
Oceanview
-
Balcony
$51,100
Suite
-
From
US$51,100
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ships: Scenic Eclipse II
Departures: Mar 2027 to Mar 2028
Visit: Chile, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,345
Suite
$23,332
From
US$16,345
Save 4,045
Per Person
View Trip
18 Day Valparaiso to Buenos Aires with Silversea
Cruise

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 29 January 2028
Visit: Chile, Argentina, Falkland Islands
All-Inclusive Fare
Inside
-
Oceanview
$13,800
Balcony
$15,500
Suite
$42,500
From
US$13,800
Per Person
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Brazil
Inside
-
Oceanview
-
Balcony
$26,680
Suite
-
From
US$26,680
Per Person
View Trip
13 Day Chairman’s Voyage: Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 November 2027
Visit: Chile, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,258
Suite
$29,067
From
US$21,258
Save 2,517
Per Person
View Trip
22 Day Lima (Callao) to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 January 2028
Visit: Peru, Chile, Argentina, Falkland Islands
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,800
Suite
$28,000
From
US$16,800
Save 3,500
Per Person
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Nov 2026 to Nov 2028
Visit: Chile, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,645
Suite
$25,734
From
US$15,645
Save 4,270
Per Person
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Oct 2027 to Nov 2027
Visit: Chile, Argentina
Inside
-
Oceanview
$10,020
Balcony
$10,740
Suite
$19,500
From
US$10,020
Per Person
View Trip
21 Day Rio De Janeiro To San Antonio with Cunard
Cruise

21 Days (20 Nights) Rio de Janeiro to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 08 February 2027
Visit: Brazil, Uruguay, Argentina, Chile
Bonus Onboard Credit
Inside
$4,699
Oceanview
$6,999
Balcony
$7,999
Suite
-
From
US$4,699
Per Person
View Trip
12 Day Puerto Williams to Valparaiso with Silversea
Cruise

12 Days (11 Nights) Puerto Williams to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 27 February 2027
Visit: Chile, Argentina
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$21,700
From
US$21,700
Save 1,500
Per Person
View Trip
18 Day Fjords & Glaciers of Southern Chile & Patagonia with Scenic
New ReleaseCruise

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Feb 2029
Visit: Argentina, Chile, Uruguay
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,108
Suite
$28,669
From
US$13,108
Save 3,517
Per Person
View Trip
17 Day Patagonia & the Chilean Fjords with Scenic
New ReleaseCruise

17 Days (16 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 November 2027
Visit: Argentina, Uruguay, Chile
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,958
Suite
$24,422
From
US$19,958
Save 3,587
Per Person
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Nov 2026 to Nov 2026
Visit: Chile, Argentina
Inside
-
Oceanview
-
Balcony
$13,000
Suite
$24,410
From
US$13,000
Per Person
View Trip
37 Day Caribbean To Cape Horn with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$10,649
Oceanview
$10,999
Balcony
-
Suite
-
From
US$10,649
Save 10,649
Per Person
View Trip
38 Day Fort Lauderdale To San Antonio with Cunard
Cruise

38 Days (37 Nights) Fort Lauderdale to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil, Uruguay, Argentina, Chile
Bonus Onboard Credit
Inside
$7,398
Oceanview
$10,233
Balcony
$11,230
Suite
$24,780
From
US$7,398
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Valparaiso
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 January 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,649
Oceanview
$6,949
Balcony
$10,099
Suite
-
From
US$6,649
Save 6,649
Per Person
View Trip
22 Day Antarctica & Chilean Fjords Cruise: Buenos Aires, Ushuaia & Santiago with Azamara Cruises
Cruise
 (3)

22 Days (21 Nights) Buenos Aires to Santiago
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Azamara Always Included
Inside
$11,089
Oceanview
$11,779
Balcony
$15,469
Suite
$21,069
From
US$11,089
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Valparaiso to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,599
Oceanview
$6,999
Balcony
$9,599
Suite
-
From
US$6,599
Save 6,599
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$20,849
Oceanview
$21,499
Balcony
$28,649
Suite
-
From
US$20,849
Save 20,849
Per Person
View Trip
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+5 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Yours to Explore
Inside
-
Oceanview
$37,999
Balcony
$42,999
Suite
-
From
US$37,999
Per Person
View Trip
34 Day Captain Drake's Crossroads with Oceania Cruises
Cruise
 (1)

34 Days (33 Nights) Valparaiso to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$10,199
Oceanview
$10,749
Balcony
-
Suite
-
From
US$10,199
Save 10,199
Per Person
View Trip
50 Day Valparaiso To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (5)

50 Days (49 Nights) Valparaiso to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+5 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$16,919
Oceanview
$19,119
Balcony
$23,119
Suite
$36,139
From
US$16,919
Per Person
View Trip
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