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Patagonia Luxury Cruises

Explore the best luxury cruises exploring Patagonia. Choose from 48 unique cruise itineraries with 45 past traveler reviews from 8 leading cruise lines. January is the most popular month to join a luxury cruise exploring Patagonia with 54 departures starting between February 2026 and February 2029.
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121 Days
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48 Cruises (54 Cruise Departures)
29 Day Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 30 January 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Fly Free Premium Economy
Fly Free Business Class
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$45,565
Suite
$51,167
From
US$45,565
Save 23,805
Per Person
View Trip
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Fly Free Premium Economy
Fly Free Business Class
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$41,239
Suite
$48,029
From
US$41,239
Save 26,016
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$38,983
Suite
$39,735
From
US$38,983
Save 23,905
Per Person
View Trip
26 Day Ultimate Ancient Treasures, Fjords & Wonders of South America with Scenic
New ReleaseCruise

26 Days (25 Nights) Panama City to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 31 October 2027
Visit: Panama, Colombia, Ecuador, Peru, Chile, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$71,899
Suite
$97,604
From
US$71,899
Save 2,081
Per Person
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Nov 2026 to Nov 2026
Visit: Chile, Argentina
Inside
-
Oceanview
-
Balcony
$12,450
Suite
$24,410
From
US$12,450
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$5,642
Oceanview
$6,210
Balcony
$8,261
Suite
$11,142
From
US$5,642
Save 7,156
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$4,305
Oceanview
$4,693
Balcony
$6,148
Suite
$8,670
From
US$4,305
Save 4,493
Per Person
View Trip
11 Day Chile Intensive Cruise: Punta Arenas, Chilean Fjords & San Antonio with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Ushuaia to Santiago
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 20 February 2026
Visit: Argentina, Chile
Azamara Always Included
Inside
-
Oceanview
$2,289
Balcony
-
Suite
-
From
US$2,289
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
$3,174
Oceanview
$3,717
Balcony
$4,551
Suite
$6,976
From
US$3,174
Save 75
Per Person
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Oct 2027 to Nov 2027
Visit: Chile, Argentina
Inside
-
Oceanview
$10,550
Balcony
$11,310
Suite
$18,470
From
US$10,550
Per Person
View Trip
19 Day Buenos Aires to Valparaiso with Silversea
Cruise

19 Days (18 Nights) Buenos Aires to Valparaiso
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 26 February 2026
Visit: Argentina, Uruguay, Falkland Islands, Chile
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$12,720
Balcony
-
Suite
-
From
US$12,720
Save 3,180
Per Person
View Trip
12 Day Puerto Williams to Valparaiso with Silversea
Cruise

12 Days (11 Nights) Puerto Williams to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 27 February 2027
Visit: Chile, Argentina
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$8,080
Balcony
$9,520
Suite
$15,110
From
US$8,080
Save 2,020
Per Person
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Visit: Chile, Argentina
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,171
Suite
-
From
US$16,171
Save 22,219
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 08 March 2027
Visit: Chile, Argentina
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,049
Suite
$25,331
From
US$15,049
Save 18,671
Per Person
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visit: Peru, Chile, Argentina
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$27,158
Suite
-
From
US$27,158
Save 22,997
Per Person
View Trip
18 Day Fjords & Glaciers of Southern Chile & Patagonia with Scenic
New ReleaseCruise

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Feb 2029
Visit: Argentina, Chile, Uruguay
Early Booking Savings
Fly Free Business Class
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,851
Suite
$25,684
From
US$12,851
Save 26,113
Per Person
View Trip
22 Day Lima (Callao) to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 January 2028
Visit: Peru, Chile, Argentina, Falkland Islands
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,170
Suite
$28,240
From
US$16,170
Save 6,930
Per Person
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Brazil
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$22,753
Suite
-
From
US$22,753
Save 22,402
Per Person
View Trip
18 Day Valparaiso to Buenos Aires with Silversea
Cruise

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 29 January 2028
Visit: Chile, Argentina, Falkland Islands
All-Inclusive Fare
Inside
-
Oceanview
$13,800
Balcony
$15,500
Suite
-
From
US$13,800
Per Person
View Trip
17 Day Patagonia & the Chilean Fjords with Scenic
New ReleaseCruise

17 Days (16 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 November 2027
Visit: Argentina, Uruguay, Chile
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,532
Suite
$18,879
From
US$15,532
Save 19,458
Per Person
View Trip
21 Day Rio De Janeiro To San Antonio with Cunard
Cruise

21 Days (20 Nights) Rio de Janeiro to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 08 February 2027
Visit: Brazil, Uruguay, Argentina, Chile
Inside
$4,699
Oceanview
$7,138
Balcony
$8,029
Suite
-
From
US$4,699
Per Person
View Trip
13 Day Chairman’s Voyage: Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 November 2027
Visit: Chile, Argentina
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,529
Suite
$25,998
From
US$18,529
Save 22,461
Per Person
View Trip
38 Day Fort Lauderdale To San Antonio with Cunard
Cruise

38 Days (37 Nights) Fort Lauderdale to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil, Uruguay, Argentina, Chile
Exclusive Savings
Inside
$6,788
Oceanview
$10,065
Balcony
$11,570
Suite
$24,193
From
US$6,788
Per Person
View Trip
34 Day Captain Drake's Crossroads with Oceania Cruises
Cruise
 (1)

34 Days (33 Nights) Valparaiso to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$9,791
Oceanview
$10,082
Balcony
$14,447
Suite
$20,170
From
US$9,791
Save 10,207
Per Person
View Trip
21 Day Spectacular Antarctica with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) San Antonio to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 February 2026
Visit: Chile, Argentina, Antarctica, Falkland Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,489
Suite
-
From
US$8,489
Save 8,909
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$20,133
Oceanview
$20,958
Balcony
$27,408
Suite
$38,466
From
US$20,133
Save 20,965
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Valparaiso
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 January 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$6,259
Oceanview
$6,647
Balcony
$9,024
Suite
$13,146
From
US$6,259
Save 6,539
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Valparaiso to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$6,500
Oceanview
$6,839
Balcony
$9,216
Suite
$12,368
From
US$6,500
Save 6,798
Per Person
View Trip
19 Day Antarctic Encounter with Regent Seven Seas
Cruise

19 Days (18 Nights) Buenos Aires to Lima
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 20 February 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile, Peru
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,752
Suite
$15,614
From
US$13,752
Save 21,646
Per Person
View Trip
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+5 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Savings
Inside
-
Oceanview
$37,371
Balcony
$42,271
Suite
-
From
US$37,371
Save 628
Per Person
View Trip
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