Home > Cruises > South America Cruises > Patagonia Cruises > Luxury Cruises

Patagonia Luxury Cruises

Explore the best luxury cruises exploring Patagonia. Choose from 48 unique cruise itineraries with 45 past traveler reviews from 8 leading cruise lines. January is the most popular month to join a luxury cruise exploring Patagonia with 54 departures starting between February 2026 and February 2029.
Filter Results
Departures
Show More...
Duration
11 Days
121 Days
Types
Ship Size
Cruise Lines
Show More...
Price
$2,200pp
$133,998pp
Countries
Show More...
Filter Results
48 Cruises (54 Cruise Departures)
50 Day Valparaiso To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (4)

50 Days (49 Nights) Valparaiso to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+5 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$17,404
Oceanview
$18,665
Balcony
$22,545
Suite
$34,214
From
US$17,404
Save 415
Per Person
View Trip
19 Day Antarctic Encounter with Regent Seven Seas
Cruise

19 Days (18 Nights) Buenos Aires to Lima
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 20 February 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile, Peru
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,752
Suite
$15,614
From
US$13,752
Save 21,646
Per Person
View Trip
31 Day Chilean Fjords, Glaciers & Antarctic Wildlife Explorer with Scenic
Cruise

31 Days (30 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Visit: Chile, Argentina, Falkland Islands, South Georgia Island, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$99,972
Suite
-
From
US$99,972
Save 2,983
Per Person
View Trip
24 Day Ultimate Chilean Fjords & Antarctica’s Weddell Sea with Scenic
New ReleaseCruise

24 Days (23 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 November 2027
Visit: Chile, Argentina, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$84,842
Suite
$173,888
From
US$84,842
Save 2,438
Per Person
View Trip
29 Day Ultimate Antarctica & the Fjords of Southern Chile with Scenic
New ReleaseCruise

29 Days (28 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Feb 2029
Visit: Argentina, Antarctica, Chile, Uruguay
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$70,995
Suite
$108,184
From
US$70,995
Save 2,715
Per Person
View Trip
55 Day Epic Antarctic & Amazon with Oceania Cruises
Cruise
 (1)

55 Days (54 Nights) Valparaiso to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands (+6 more), Uruguay, Brazil, Barbados, Antigua and Barbuda, Virgin Islands, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$15,577
Oceanview
$16,110
Balcony
$22,900
Suite
$31,824
From
US$15,577
Save 16,221
Per Person
View Trip
83 Day South America Discovery with Cunard
Cruise

83 Days (82 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 10 January 2027
Visit: England, Bermuda, USA, Turks and Caicos Islands (+10 more), Barbados, Brazil, Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba, Portugal
Exclusive Savings
Inside
$13,068
Oceanview
$18,117
Balcony
$20,058
Suite
$40,016
From
US$13,068
Per Person
View Trip
57 Day South America Discovery From Fort Lauderdale with Cunard
Cruise

57 Days (56 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil (+7 more), Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba
Exclusive Savings
Inside
$11,019
Oceanview
$14,682
Balcony
$15,375
Suite
$35,175
From
US$11,019
Per Person
View Trip
54 Day Chilean Fjords, Antarctica & South Atlantic Explorer with Seabourn
Cruise
 (1)

54 Days (53 Nights) Valparaiso to Cape Town
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 February 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+4 more), Uruguay, Saint Helena, South Africa, Mozambique
Exclusive Savings
Inside
-
Oceanview
$35,386
Balcony
$39,306
Suite
-
From
US$35,386
Save 613
Per Person
View Trip
37 Day Caribbean To Cape Horn with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$10,245
Oceanview
$10,778
Balcony
$14,513
Suite
$20,527
From
US$10,245
Save 10,653
Per Person
View Trip
83 Day South America, Antarctica, South Atlantic & Africa with Seabourn
Cruise
 (1)

83 Days (82 Nights) Miami to Cape Town
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+8 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique
Exclusive Savings
Inside
-
Oceanview
$54,079
Balcony
$60,939
Suite
$111,899
From
US$54,079
Save 920
Per Person
View Trip
41 Day Buenos Aires To Miami Grand Voyage with Azamara Cruises
Cruise
 (3)

41 Days (40 Nights) Buenos Aires to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica (+7 more), Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Exclusive Savings
Inside
$16,174
Oceanview
$16,581
Balcony
$19,317
Suite
$30,443
From
US$16,174
Save 385
Per Person
View Trip
69 Day Miami To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (4)

69 Days (68 Nights) Miami to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+13 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$22,787
Oceanview
$26,511
Balcony
$31,943
Suite
$46,028
From
US$22,787
Save 522
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (4)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Exclusive Savings
Inside
$25,403
Oceanview
$29,613
Balcony
$35,821
Suite
$51,826
From
US$25,403
Save 586
Per Person
View Trip
75 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (3)

75 Days (74 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+18 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Peru, Panama, Costa Rica, Colombia, Mexico
Azamara Always Included
Exclusive Savings
Inside
$28,068
Oceanview
$29,261
Balcony
$33,810
Suite
$53,443
From
US$28,068
Save 661
Per Person
View Trip
66 Day Grand South America Mosaic with Regent Seven Seas
Cruise

66 Days (65 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 13 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Costa Rica, Panama, Ecuador, Peru, Chile, Antarctica, Falkland Islands, Argentina, Uruguay, Brazil, Saint Lucia, Saint Kitts and Nevis
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$51,107
Suite
$53,214
From
US$51,107
Save 82,891
Per Person
View Trip
121 Day Cape To Cape World Cruise: Miami To Dover with Seabourn
Cruise
 (1)

121 Days (120 Nights) Miami to London
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+20 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal, France, England
Exclusive Savings
Inside
-
Oceanview
$76,702
Balcony
$87,482
Suite
$163,922
From
US$76,702
Save 1,297
Per Person
View Trip
113 Day Cape To Cape World Cruise: Miami To Lisbon with Seabourn
Cruise
 (1)

113 Days (112 Nights) Miami to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+18 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
$71,586
Balcony
$80,406
Suite
-
From
US$71,586
Save 1,213
Per Person
View Trip
Results: 31-48 of 48

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

Coach Cruises Luxury Cruises

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

About Us | View Your Booking | Operators | Terms & Conditions | Site Map | We're hiring!

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations