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Med Cruises Starting In September 2025

If you're looking at joining a cruise sailing in and around the Mediterranean in September 2025, we have 116 unique cruises with 1,569 departures from the world's leading cruise lines departing in September.
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116 Cruises (1,569 Cruise Departures)
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+10 more), Viking Libra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Sep 2025 to Sep 2028
Countries Visited: Italy, Monaco, France, Spain
Mutiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,799
Save
1,750
From
2,599
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC World Asia, MSC World Europa
Departures: Sep 2025 to Oct 2027
Countries Visited: Spain, France, Italy, Sicily, Malta
Mutiple Deals Available
Inside
$630
Oceanview
$760
Balcony
$880
Suite
$1,600
From
630
per person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Sep 2025 to Sep 2026
Countries Visited: Italy, France, Spain, Portugal, Sardinia
Exclusive Savings + Onboard Credit
Inside
$1,267
Oceanview
$1,377
Balcony
$1,889
Suite
$2,823
From
1,267
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: Aug 2025 to Oct 2026
Countries Visited: Italy, Spain, France
Mutiple Deals Available
Inside
$981
Oceanview
$1,121
Balcony
$1,261
Suite
$1,970
From
981
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Aug 2025 to Oct 2026
Countries Visited: Spain, Italy, France
Exclusive Savings + Onboard Credit
Inside
$869
Oceanview
$989
Balcony
$1,169
Suite
$1,531
From
869
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Aug 2025 to Nov 2025
Countries Visited: Italy, France, Spain, Sardinia
Epic Europe Sale
Inside
$777
Oceanview
$907
Balcony
$1,027
Suite
$1,867
From
777
per person
View Trip
15 Day An Extended Journey Of Côte d'Azur And Golden Playas with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 08 September 2025
Countries Visited: Spain, Monaco, France, Italy, Corsica, Sardinia, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$19,050
From
19,050
per person
View Trip
15 Day Italy & Spain with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) London to London
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 13 September 2025
Countries Visited: England, Gibraltar, France, Italy, Sardinia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$15,088
Save
9,334
From
15,088
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Cagliari to Cagliari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Sep 2025 to Nov 2025
Countries Visited: Sardinia, Italy, France, Spain
Inside
$804
Oceanview
$974
Balcony
$1,174
Suite
-
From
804
per person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Olbia to Olbia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 12 September 2025
Countries Visited: Sardinia, Italy, France, Spain, Portugal
Inside
$1,412
Oceanview
-
Balcony
-
Suite
-
From
1,412
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Sep 2025 to Oct 2025
Countries Visited: France, Spain, Sardinia, Italy
Inside
$780
Oceanview
$950
Balcony
$1,150
Suite
$1,870
From
780
per person
View Trip
13 Day Palazzi & Rivieras with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Valletta to Malaga
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 25 September 2025
Countries Visited: Malta, Tunisia, Sicily, Italy, Corsica, France, Spain
Summer Of Choice
Inside
$4,249
Oceanview
-
Balcony
$6,949
Suite
-
Save
4,249
From
4,249
per person
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 30 September 2025
Countries Visited: Italy, France, Spain
Inside
$1,952
Oceanview
-
Balcony
$2,600
Suite
$5,377
Save
1,192
From
1,952
per person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise

7 Days (6 Nights) Marseille to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 28 September 2025
Countries Visited: France, Italy, Sicily, Malta, Spain
Inside
-
Oceanview
$768
Balcony
$968
Suite
$1,388
From
768
per person
View Trip
11 Day Spotlight With Chef Kent Rathbun with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 September 2025
Countries Visited: Spain, France, Italy, Malta, Greece
Inside
-
Oceanview
-
Balcony
$10,049
Suite
$10,899
Save
15,149
From
10,049
per person
View Trip
15 Day An Extended Journey To Modernist Masterpieces And Sunny Shores with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Sardinia, Spain, France
Inside
-
Oceanview
-
Balcony
-
Suite
$18,050
From
18,050
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC World Asia, MSC World Europa
Departures: Aug 2025 to Oct 2027
Countries Visited: France, Italy, Sicily, Malta, Spain
Exclusive Savings + Onboard Credit
Inside
$621
Oceanview
$751
Balcony
$871
Suite
$1,591
From
621
per person
View Trip
8 Day Corsican Shores, Under Sail Aboard Le Ponant with Ponant
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departures: Sep 2025 to Sep 2026
Countries Visited: France, Corsica
Inside
-
Oceanview
$12,220
Balcony
$17,550
Suite
$17,600
From
12,220
per person
View Trip
8 Day Rome To Barcelona with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
Inside
$939
Oceanview
-
Balcony
-
Suite
-
From
939
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Tarragona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 13 September 2025
Countries Visited: Spain, France, Italy, Sicily, Malta
Epic Europe Sale
Inside
-
Oceanview
$856
Balcony
$1,166
Suite
$1,933
From
856
per person
View Trip
22 Day An Extended Journey Through Mediterranean Charm, Rugged Beauty And Iconic Culture with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 22 September 2025
Countries Visited: Spain, France, Italy, Sicily (+4 more), Tunisia, Monaco, Sardinia, Corsica
Inside
-
Oceanview
-
Balcony
-
Suite
$26,835
From
26,835
per person
View Trip
22 Day An Extended Journey Of Ancient Medinas, Striking Ruins And Paradise Landscapes with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 01 September 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+4 more), Monaco, France, Corsica, Sardinia
Inside
-
Oceanview
-
Balcony
-
Suite
$26,120
From
26,120
per person
View Trip
8 Day Corfu, Dubrovnik & More with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Athens to Athens
Cruise Line: Virgin Voyages
Ships: Resilient Lady, Scarlet Lady
Departures: Sep 2025 to May 2026
Countries Visited: Greece, Montenegro, Croatia
Swing Into Savings Best Rate
Inside
$1,680
Oceanview
$1,674
Balcony
$2,031
Suite
$4,193
From
1,674
per person
View Trip
8 Day Mediterranean with Greece & Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 13 September 2025
Countries Visited: Greece, Montenegro, Sicily, Spain
Exclusive Deal
Inside
$1,570
Oceanview
-
Balcony
$2,731
Suite
-
From
1,570
per person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Livorno to Livorno
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Seaside
Departures: Aug 2025 to Oct 2027
Countries Visited: Italy, France, Spain, Tunisia, Sicily
Mutiple Deals Available
Inside
$936
Oceanview
$1,136
Balcony
$1,276
Suite
$1,807
From
936
per person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Valencia to Marseille
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 25 September 2025
Countries Visited: Spain, France
Inside
$99
Oceanview
-
Balcony
$199
Suite
$349
From
99
per person
View Trip
9 Day Rome to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 23 September 2025
Countries Visited: Italy, Spain
Port-to-PortDoor-to-Door Upgrade Option
Inside
-
Oceanview
-
Balcony
-
Suite
$9,500
From
9,500
per person
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 22 September 2025
Countries Visited: Spain, France, Corsica, Italy
Inside
$1,163
Oceanview
-
Balcony
-
Suite
-
From
1,736
per person
View Trip
13 Day Barcelona to Cannes, Rome & Tuscany with Virgin Voyages
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 25 September 2025
Countries Visited: Spain, France, Corsica, Sardinia, Italy
Swing Into Savings Best Rate
Inside
-
Oceanview
-
Balcony
-
Suite
$7,333
From
7,333
per person
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: Sep 2025 to Oct 2025
Countries Visited: Italy, Spain
Inside
$1,625
Oceanview
$3,063
Balcony
$1,672
Suite
$4,490
Save
4,784
From
1,625
per person
View Trip
Results: 1-30 of 116

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Country Routes

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Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

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