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Spain Cruises Starting In September 2025

If you're looking at joining a cruise to Spain in September 2025, we have 38 unique cruise itineraries and 616 departures available, operated by eleven of the world's leading cruise lines departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
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18 Days
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38 Cruises (616 Cruise Departures)
9 Day Cruising Southern Spain and Portugal - with Smithsonian Journeys with Ponant
Cruise
 (2)

9 Days (8 Nights) Barcelona to Lisbon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 16 September 2025
Countries Visited: Spain, Portugal
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$10,100
SUITE
$21,790
From (per person) 10,100
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Harmony of the Seas
Departures: Jun 2025 to Aug 2026
Countries Visited: Spain, Italy
Latest Offer
INSIDE
$1,025
OCEANVIEW
$1,335
BALCONY
$1,317
SUITE
$2,677
Save (per person) 1,173
From (per person) 1,340
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: Jul 2025 to Aug 2026
Countries Visited: Italy, Spain
Latest Offer
INSIDE
$1,371
OCEANVIEW
$1,511
BALCONY
$1,724
SUITE
$3,472
Save (per person) 6,479
From (per person) 1,381
View Trip
9 Day Iberian Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Lisbon to Barcelona
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 24 September 2025
Countries Visited: Portugal, Spain
INSIDE
-
OCEANVIEW
-
BALCONY
$6,900
SUITE
-
From (per person) 6,900
View Trip
9 Day Rome to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 23 September 2025
Countries Visited: Italy, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,300
From (per person) 9,300
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Libra (+9 more), Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Sep 2025 to Sep 2027
Countries Visited: Italy, Monaco, France, Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$2,799
SUITE
$3,799
Save (per person) 1,000
From (per person) 2,799
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: Jun 2025 to Oct 2026
Countries Visited: Italy, Spain, France
Escape To SeaDrinks and Wi-Fi Included
INSIDE
$951
OCEANVIEW
$1,121
BALCONY
$1,241
SUITE
$1,957
From (per person) 951
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Jun 2025 to Oct 2026
Countries Visited: Spain, Italy, France
Escape To Sea
INSIDE
$909
OCEANVIEW
$999
BALCONY
$1,158
SUITE
$1,648
From (per person) 909
View Trip
8 Day Barcelona To Istanbul with Cunard
Cruise

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Sep 2025 to May 2026
Countries Visited: Spain, Greece, Turkey
Exclusive Deal
INSIDE
$959
OCEANVIEW
$1,129
BALCONY
$1,299
SUITE
$2,559
From (per person) 959
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Harmony of the Seas
Departures: Jul 2025 to Oct 2026
Countries Visited: Spain, France, Italy
Latest Offer
INSIDE
$1,135
OCEANVIEW
$1,535
BALCONY
$1,546
SUITE
$2,892
Save (per person) 1,055
From (per person) 1,135
View Trip
8 Day Rome To Barcelona with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$789
OCEANVIEW
$899
BALCONY
$1,029
SUITE
$1,899
From (per person) 789
View Trip
12 Day Canaries & Portugal Cruise with Celebrity Cruises
Cruise
 (1)

12 Days (11 Nights) London to London
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departures: Sep 2025 to Oct 2026
Countries Visited: England, Portugal, Spain
Mutiple Deals Available
INSIDE
$2,271
OCEANVIEW
$2,462
BALCONY
$3,071
SUITE
$5,723
Save (per person) 1,405
From (per person) 2,431
View Trip
17 Day Escapades In Iberia with Regent Seven Seas
Cruise

17 Days (16 Nights) Paris to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 September 2025
Countries Visited: France, Spain, Portugal
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$32,299
Save (per person) 43,899
From (per person) 32,299
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jul 2025 to Sep 2026
Countries Visited: Italy, France, Spain
Exclusive DealBonus Onboard Credit + Save
INSIDE
$1,258
OCEANVIEW
$1,309
BALCONY
$1,426
SUITE
$3,997
Save (per person) 1,268
From (per person) 1,258
View Trip
11 Day Flamenco & Jaleo with Regent Seven Seas
Cruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 14 September 2025
Countries Visited: Portugal, Spain, France
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,699
Save (per person) 16,899
From (per person) 10,699
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: Jun 2025 to Oct 2026
Countries Visited: Spain, France, Italy
Escape To Sea
INSIDE
$959
OCEANVIEW
$1,129
BALCONY
$1,249
SUITE
$1,921
From (per person) 959
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Cannes to Cannes
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaview
Departures: Jun 2025 to Oct 2026
Countries Visited: France, Italy, Spain
Escape To SeaDrinks and Wi-Fi Included
INSIDE
$967
OCEANVIEW
$1,137
BALCONY
$1,278
SUITE
$1,787
From (per person) 967
View Trip
8 Day A Journey to White Isle Bohemia & Italian Riviera Romance with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Italy
Best Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$4,120
SUITE
$6,315
From (per person) 4,120
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Barcelona to Rome
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Sep 2025 to Sep 2027
Countries Visited: Spain, France, Monaco, Italy
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$2,799
SUITE
$3,799
Save (per person) 700
From (per person) 2,799
View Trip
15 Day Istanbul And Greek Islands with Cunard
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 29 September 2025
Countries Visited: Spain, Greece, Turkey
Exclusive Deal
INSIDE
$1,659
OCEANVIEW
$1,789
BALCONY
$2,389
SUITE
$4,829
From (per person) 1,659
View Trip
18 Day Crossing the Equator: Portugal to Brazil with Scenic
Cruise

18 Days (17 Nights) Lisbon to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 24 September 2025
Countries Visited: Portugal, Spain, Brazil
2 for 1 Fares + Fly Free Premium Economy2 for 1 Fares + Fly Free Business Class
INSIDE
-
OCEANVIEW
-
BALCONY
$12,465
SUITE
$22,715
Save (per person) 12,525
From (per person) 12,465
View Trip
8 Day Western Europe with MSC Cruises
Cruise

8 Days (7 Nights) London to London
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 27 September 2025
Countries Visited: England, Spain, France
Exclusive Deal
INSIDE
$1,944
OCEANVIEW
$2,444
BALCONY
$2,644
SUITE
$4,024
From (per person) 1,944
View Trip
8 Day Northern Europe with MSC Cruises
Cruise

8 Days (7 Nights) London to London
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 06 September 2025
Countries Visited: England, Spain, France
Drinks and Wi-Fi Included
INSIDE
$1,183
OCEANVIEW
$1,433
BALCONY
$1,533
SUITE
$2,573
From (per person) 1,183
View Trip
10 Day Spanish Flair Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) London to London
Cruise Line: Royal Caribbean
Ships: Independence of the Seas, Liberty of the Seas
Departures: Jul 2025 to Sep 2026
Countries Visited: England, Spain, Portugal
Latest Offer
INSIDE
$1,245
OCEANVIEW
$1,496
BALCONY
$1,945
SUITE
$3,179
Save (per person) 841
From (per person) 1,245
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Jun 2025 to Oct 2026
Countries Visited: France, Spain, Italy
Escape To Sea
INSIDE
$821
OCEANVIEW
$911
BALCONY
$1,011
SUITE
$1,704
From (per person) 821
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Jun 2025 to Oct 2026
Countries Visited: Spain, Italy, France
Escape To Sea
INSIDE
$824
OCEANVIEW
$914
BALCONY
$1,084
SUITE
$1,768
From (per person) 824
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: Jul 2025 to Oct 2026
Countries Visited: Italy, Spain, France
Latest Offer
INSIDE
$1,321
OCEANVIEW
$1,765
BALCONY
$2,123
SUITE
$4,074
Save (per person) 1,243
From (per person) 1,321
View Trip
9 Day Monte Carlo to Rome with Silversea
Cruise

9 Days (8 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 September 2025
Countries Visited: Monaco, France, Spain, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,600
From (per person) 9,600
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Splendida
Departures: Jun 2025 to Oct 2026
Countries Visited: Italy, France, Spain
Escape To Sea
INSIDE
$834
OCEANVIEW
$924
BALCONY
$1,024
SUITE
$1,517
From (per person) 834
View Trip
10 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2025 to Sep 2026
Countries Visited: Spain, Portugal, Morocco
Exclusive DealBonus Onboard Credit + Save
INSIDE
$1,488
OCEANVIEW
$1,546
BALCONY
$1,816
SUITE
$5,236
Save (per person) 1,592
From (per person) 1,546
View Trip
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