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Panama Tours & Cruises Starting In December 2025

If you're looking at joining a tour to Panama in December 2025, we have 18 unique cruises, small group tours and adventures with 184 departures from the world's leading tour operators departing in December.
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Departures (December 2025)
< November 2025 January 2026 >
Duration
11 Days
139 Days
Types
Start & End Cities
Operators
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Price
$1,300pp
$132,495pp
Countries
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18 Trips (184 Trip Departures)
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Costa Rica, Panama
Limited Time Sale
Save 302
From 1,608
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18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking Cruises
Ships: Viking Neptune, Viking Sky
Departures: Oct 2024 to Dec 2025
Countries Visited: USA, Mexico, Colombia, Panama (+1 more), Costa Rica
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INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$19,795
Save 1,110
From 9,895
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17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (2)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 23 December 2025
Countries Visited: USA, Aruba, Panama, Costa Rica (+2 more), Nicaragua, Mexico
INSIDE
$3,273
OCEANVIEW
$3,579
BALCONY
$4,730
SUITE
$5,420
From 3,273
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (4)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2024 to Dec 2025
Countries Visited: Panama, Costa Rica, Honduras, Belize (+2 more), Mexico, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$5,638
SUITE
$8,905
Save 1,073
From 5,638
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17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (1)

17 Days (16 Nights) San Francisco to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Jan 2025 to Dec 2025
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Colombia
INSIDE
$2,956
OCEANVIEW
$3,228
BALCONY
$4,491
SUITE
$5,216
From 2,956
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (4)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2024 to Dec 2025
Countries Visited: USA, Mexico, Belize, Honduras (+2 more), Costa Rica, Panama
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INSIDE
-
OCEANVIEW
-
BALCONY
$5,440
SUITE
$8,410
Save 1,073
From 5,440
View Trip
12 Day Panama Canal & Perfect Day Holiday with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 22 December 2025
Countries Visited: USA, Colombia, Panama, Aruba (+2 more), Curacao, Bahamas
Exclusive Offer
INSIDE
$3,491
OCEANVIEW
$3,998
BALCONY
$4,699
SUITE
$12,211
Save 3,794
From 3,491
View Trip
28 Day Amazing Central America with Intrepid Travel
Tour

28 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Guatemala, Honduras, El Salvador, Nicaragua (+2 more), Costa Rica, Panama
Limited Time Sale
Save 655
From 3,480
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16 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Los Angeles to Miami
Ships: Norwegian Bliss, Norwegian Encore (+1 more), Norwegian Joy
Departures: Oct 2025 to Feb 2026
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Colombia
Free At Sea OfferExclusive Solo Offer
INSIDE
$4,177
OCEANVIEW
$5,164
BALCONY
$5,737
SUITE
$6,496
From 4,177
View Trip
13 Day Panama Canal Sunfarer with Holland America
Cruise
 (2)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Nov 2025 to Dec 2025
Countries Visited: USA, Bahamas, Curacao, Colombia (+3 more), Panama, Costa Rica, Jamaica
Have It All Offer
INSIDE
$3,677
OCEANVIEW
$4,618
BALCONY
$5,014
SUITE
$6,449
From 3,677
View Trip
15 Day Panama Canal & Central America with Viking Cruises
Cruise
 (4)

15 Days (14 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2024 to Feb 2026
Countries Visited: USA, Jamaica, Panama, Costa Rica (+3 more), Honduras, Belize, Mexico
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$7,420
SUITE
$12,667
Save 1,091
From 7,420
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 23 December 2025
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
INSIDE
$2,305
OCEANVIEW
$2,465
BALCONY
$3,453
SUITE
$4,374
From 2,305
View Trip
12 Day Central America with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Ships: Norwegian Gem, Norwegian Jade
Departures: Nov 2024 to Dec 2025
Countries Visited: USA, Cayman Islands, Colombia, Panama (+3 more), Costa Rica, Belize, Mexico
Free At Sea Offer
INSIDE
$3,429
OCEANVIEW
$3,883
BALCONY
$5,452
SUITE
$5,953
From 3,429
View Trip
11 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Panama City
Ship: Norwegian Jade
Departure: 12 December 2025
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Cayman Islands, Colombia, Panama
Free At Sea OfferExclusive Solo Offer
INSIDE
$3,087
OCEANVIEW
$3,543
BALCONY
$4,757
SUITE
$5,137
From 3,087
View Trip
12 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Ship: Norwegian Pearl
Departures: Jan 2025 to Jan 2026
Countries Visited: USA, Jamaica, Colombia, Panama (+3 more), Costa Rica, Belize, Mexico
Free At Sea Offer
INSIDE
$3,352
OCEANVIEW
$4,097
BALCONY
$5,798
SUITE
$6,101
From 3,352
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ships: Caribbean Princess, Emerald Princess
Departures: Jan 2025 to Jan 2026
Countries Visited: USA, Aruba, Bonaire, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
INSIDE
$2,083
OCEANVIEW
$2,132
BALCONY
$3,231
SUITE
$4,152
From 2,083
View Trip
14 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

14 Days (13 Nights) Panama City to New York
Ship: Norwegian Jade
Departure: 22 December 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+5 more), Saint Lucia, Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
Free At Sea OfferExclusive Solo Offer
INSIDE
$4,531
OCEANVIEW
$5,290
BALCONY
$7,187
SUITE
$8,327
From 4,531
View Trip
139 Day Viking World Cruise with Viking Cruises
Cruise
 (5)

139 Days (138 Nights) Fort Lauderdale to London
Cruise Line: Viking Cruises
Ship: Viking Sky
Departures: Dec 2024 to Dec 2025
Countries Visited: USA, Mexico, Colombia, Panama (+25 more), Costa Rica, Nicaragua, French Polynesia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Singapore, Myanmar, Sri Lanka, India, Saudi Arabia, Jordan, Egypt, Israel, Turkey, Greece, Sicily, Italy, Monaco, Spain, Portugal, France, England
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$94,075
SUITE
$152,875
Save 2,200
From 94,075
View Trip
Results: 18 results

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Central America Tours

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Travel Styles

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Trip Lengths

1 Month 10 Day 2 Week 3 Week 4 Week

Departure Months

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