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Italy Cruises Starting In April 2027 and 2028

If you're looking at joining a cruise to Italy in April 2027 or 2028, we have 264 unique cruise itineraries and 3,635 departures available, operated by twenty-one of the world's leading cruise lines departing in April.
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264 Cruises (3,635 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: May 2026 to Oct 2027
Visit: Greece, Italy
Easter Flash Sale
Exclusive Savings
Inside
$999
Oceanview
$1,455
Balcony
$1,999
Suite
$2,594
From
A$999
Save 18
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 21 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$538
Oceanview
-
Balcony
$885
Suite
$1,548
From
A$538
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Exclusive Savings
Inside
$538
Oceanview
-
Balcony
$885
Suite
$1,548
From
A$538
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$453
Oceanview
$542
Balcony
$641
Suite
$1,156
From
A$453
Per Person
View Trip
5 Day A Journey Through Riviera Elegance & Coastal Splendour with Explora Journeys
Cruise
 (1)

5 Days (4 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,842
From
A$3,842
Save 78
Per Person
View Trip
6 Day A Journey From Ancient Whispers To Aegean Wonders with Explora Journeys
Cruise
 (1)

6 Days (5 Nights) Rome to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 April 2026
Visit: Italy, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$5,081
From
A$5,081
Save 104
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Florence to Valencia
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 22 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$728
Suite
-
From
A$728
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$679
Oceanview
$798
Balcony
$936
Suite
$2,033
From
A$679
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 23 April 2026
Visit: Italy, Spain
Easter Flash Sale
Exclusive Savings
Inside
-
Oceanview
$636
Balcony
$844
Suite
$1,557
From
A$636
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 20 April 2026
Visit: France, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$867
Suite
-
From
A$867
Per Person
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 20 April 2026
Visit: Italy, France
Exclusive Savings
Inside
-
Oceanview
$423
Balcony
$552
Suite
-
From
A$423
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece
Easter Flash Sale
Exclusive Savings
Inside
$920
Oceanview
$1,356
Balcony
$2,009
Suite
$2,158
From
A$920
Save 19
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Venice to Brindisi
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 April 2027
Visit: Italy, Montenegro
Exclusive Savings
Inside
$609
Oceanview
$708
Balcony
$996
Suite
$1,174
From
A$609
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Bari to Athens
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 04 April 2026
Visit: Italy, Greece
Easter Flash Sale
Exclusive Savings
Inside
$580
Oceanview
$807
Balcony
$1,035
Suite
$1,194
From
A$580
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Italy, Spain, France
Easter Flash Sale
Exclusive Savings
Inside
$722
Oceanview
$1,009
Balcony
$1,257
Suite
$2,108
From
A$722
Save 21
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Apr 2028
Visit: Greece, Turkey, Italy
Easter Flash Sale
Exclusive Savings
Inside
$831
Oceanview
$1,059
Balcony
$1,485
Suite
$1,999
From
A$831
Save 21
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Apr 2026
Visit: Italy, Spain, France
Easter Flash Sale
Exclusive Savings
Inside
$821
Oceanview
$970
Balcony
$1,346
Suite
-
From
A$821
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Spain, France, Italy
Easter Flash Sale
Exclusive Savings
Inside
$693
Oceanview
$1,069
Balcony
$1,336
Suite
$2,138
From
A$693
Save 21
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Istanbul to Istanbul
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Nov 2026 to Apr 2028
Visit: Turkey, Greece, Italy
Easter Flash Sale
Exclusive Savings
Inside
$831
Oceanview
$1,059
Balcony
$1,485
Suite
$1,999
From
A$831
Save 21
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,964
Suite
$6,414
From
A$3,964
Save 1,403
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,944
Suite
$8,864
From
A$4,944
Save 1,417
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy
Exclusive Savings
Inside
$1,980
Oceanview
$2,286
Balcony
$2,445
Suite
$3,606
From
A$1,980
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+10 more), Viking Libra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Jul 2028
Visit: Spain, France, Monaco, Italy
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,964
Suite
$6,414
From
A$3,964
Save 1,405
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Oct 2026
Visit: Spain, Italy, France
Easter Flash Sale
Exclusive Savings
Inside
$891
Oceanview
$980
Balcony
$1,376
Suite
$2,504
From
A$891
Per Person
View Trip
8 Day Canary Islands with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Lanzarote to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 05 April 2027
Visit: Spain, Morocco, Italy
Exclusive Savings
Inside
-
Oceanview
$1,277
Balcony
$1,465
Suite
-
From
A$1,277
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Lirica, MSC Orchestra
Departures: Jun 2026 to May 2028
Visit: Turkey, Greece, Italy
Easter Flash Sale
Exclusive Savings
Inside
$441
Oceanview
$540
Balcony
$659
Suite
$1,075
From
A$441
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy
Exclusive Savings
Inside
$1,970
Oceanview
$2,286
Balcony
$2,445
Suite
$3,573
From
A$1,970
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2026 to Apr 2026
Visit: Spain, France, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,111
Suite
$1,745
From
A$1,111
Per Person
View Trip
8 Day Mediterranean with Italy & Turkey with Princess
Cruise
 (6)

8 Days (7 Nights) Rome to Athens
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$1,290
Oceanview
$1,617
Balcony
$1,983
Suite
$2,419
From
A$1,290
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Apr 2026 to Oct 2026
Visit: France, Spain, Italy
Easter Flash Sale
Exclusive Savings
Inside
$900
Oceanview
$980
Balcony
$1,485
Suite
$2,712
From
A$900
Per Person
View Trip
Results: 1-30 of 264

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Cities

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Routes

Athens to Bologna Athens to Rome Athens to Venice Barcelona to Trieste Barcelona to Rome Barcelona to Venice Barcelona to Bologna Bari to Bari Bologna to Rome Genoa to Genoa Istanbul to Rome Lisbon to Rome Miami to Rome Monte Carlo to Rome Rome to Trieste Rome to Lisbon Rome to Bologna Rome to Athens Rome to Barcelona Rome to Venice Rome to Monte Carlo Rome to Fort Lauderdale Rome to Istanbul Rome to Rome Trieste to Barcelona Trieste to Rome Trieste to Trieste Trieste to Athens Venice to Venice Venice to Athens Venice to Barcelona Venice to Rome Venice to Istanbul

Country Routes

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