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Panama Tours & Cruises

Explore the colours and natural beauty of Panama - a land between the seas. Travel by dugout canoe to meet the indigenous Emberá people, visit gorgeous sun kissed islands, snorkel the Caribbean and cruise through the world famous Panama Canal. Immerse yourself in the culture and scenic beauty on one of our 341 cruises and adventures to Panama.

View all 341 Panama tours & cruises

Top Selling Tours Of Panama

Independent Panama

6 Days Panama City to Panama City

Operator: Globus

From 2,473pp

Save 334pp

Panama: Sandy Beaches & San Blas Sunsets

6 Days Panama City to Panama City

Operator: G Adventures

From 1,131pp

Save 408pp

Costa Rica, Panama from the Pacific to the Atlantic...

13 Days San Jose to San Jose

Operator: Emerald Cruises

From 14,967pp

Save 4,233pp

Secrets of Central America

11 Days Colon to Puntarenas

Operator: Ponant

From 12,002pp

Save 390pp

Discover

Must do experiences and highlights on a tour of Panama

Relax in Bocas del Toro
A stunning archipelago with palm fringed beaches and rainforest clad islands. This is the perfect place to relax and soak up some Caribbean sunshine.

Cruise the Panama Canal
Cruise through the locks of the Panama Canal where you can learn about the workings of this engineering feat and see them up close.

Snorkel with Sea Life
Immerse yourself in the underwater world of Coiba National Marine Park where you can meet turtles, angel rays and colourful fish on a snorkelling trip.

A Taste of Panama City
Explore this charismatic capital where modern glitz meets the Old Town, Casco Viejo. Relax waterside and enjoy some fresh seafood at the Mercado de Mariscos, a local seafood market that will set your tastebuds aquiver.

Get Outdoors in Boquete
A haven for lovers of outdoor adventure, here you can hike, bike and raft to your heart’s content. If you prefer a slower pace, enjoy a brew from a local coffee plantation or soak in the soothing hot springs.

Recent Reviews

What our clients are saying about their tours in and around Panama

Epic Central America Epic Central America Anna, New Zealand, Nov 2025

Great trip, food, and people. Loved all the places we visited- could have spent longer in Guatemala! Personal preference I loved the city, food and people! Third leg - Antigua to Costa Rica- not too many included activities or meals. A couple of the cities our hotel was a couple km out of the city.

Very good cruise package Panama Canal - Ocean to Ocean Rajeevkumar , Kerala, India, Sep 2025

This is my second cruise package travelling for 19 days. We enjoyed our cruise very much throughout the entire trip. Everything worked perfectly. One thing I noticed, is that Princess are charging a very high rate for WiFi. It's should be decreased. Otherwise everything was fantastic. Thank you team Princess.

Great overview adventure of Central Amaerica Best of Central America Michael, NV, United States, Sep 2019

This was an amazing way to get a good picture of the cultures, people, history, flora, fauna, geology of Central America. It's BASIX travel but have abilities to upgrade at times.