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Tours from Rome to Palermo

Are you looking for a tour from Rome to Palermo? September is the most popular month to tour between Rome and Palermo and there are 118 departures available from five of the world's leading tour operators.
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10 Days
23 Days
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$9,695pp
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9 Tours (118 Tour Departures)
14 Day Highlights of Sicily & Southern Italy with Globus
Tour
 (5)

14 Days Rome to Palermo
Operated By: Globus
Departures: May 2026 to Nov 2027
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
Exclusive Savings
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US$4,049
Save 250
Per Person
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17 Day Grand Italy & Sicily with Insight Vacations
Tour
 (13)

17 Days Rome to Palermo
Operated By: Insight Vacations
Departures: May 2026 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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Best of Summer Sale
Exclusive Savings
From
US$6,187
Save 755
Per Person
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14 Day Country Roads of Southern Italy & Sicily with Insight Vacations
Tour
 (8)

14 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Jul 2026 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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Today's Deal
Best of Summer Sale
Exclusive Savings
From
US$4,730
Save 755
Per Person
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10 Day Southern Italy and Sicily with Trafalgar
Tour
 (2)

10 Days Rome to Palermo
Operated By: Trafalgar
Departures: May 2026 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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Best of Summer Sale
Exclusive Savings
From
US$3,262
Save 428
Per Person
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23 Day Rome to Sicily with Intrepid Travel
Tour

23 Days Rome to Palermo
Operated By: Intrepid Travel
Departures: Jun 2026 to Oct 2027
Trip Styles: Adventure, Small Group, Rail
Visit: Italy, Sicily
Exclusive Savings
From
US$7,301
Save 1,415
Per Person
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13 Day Italian Escape & Sicily with Contiki
Tour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2027
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$2,975
Save 380
Per Person
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13 Day Italian Escape & Sicily (Ages 27 to 35) with Contiki
Tour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2027
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$2,710
Save 322
Per Person
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22 Day Ultimate Italy with Contiki
Tour

22 Days Rome to Palermo
Operated By: Contiki
Departures: May 2026 to Sep 2027
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$4,695
Save 590
Per Person
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22 Day Ultimate Italy (Ages 27 to 35) with Contiki
Tour

22 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$4,658
Save 502
Per Person
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Results: 9 results

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Italy & Sicily

All Italy Tours Northern Italy Tours Sicily Tours Southern Italy Tours Tuscany Tours

Travel Styles

18-30's Tours Active Adventures Coach Tours Cycling Tours Family Holidays Food & Wine Tours Luxury Tours Rail Journeys Short Breaks Small Group Tours Walking & Hiking Tours Winter Tours & Trips

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10 Day 2 Week 7 Day

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May June July August September October November March April

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Tours from Rome

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Tours from Rome to Palermo

Popular Italy Operators

APT Italy Tours CIE Italy Tours Collette Italy Tours Cosmos Italy Tours Costsaver Italy Tours Exodus Italy Tours Explore's Italy Tours G Adventures Italy Tours Globus Italy Tours Insight Vacations Italy Tours Intrepid Italy Tours Trafalgar Italy Tours

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