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Tours from Rome to Palermo

Are you looking for a tour from Rome to Palermo? September is the most popular month to tour between Rome and Palermo and there are 130 departures available from five of the world's leading tour operators.
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10 Days
23 Days
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$2,700pp
$9,695pp
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8 Tours (130 Tour Departures)
14 Day Highlights of Sicily & Southern Italy with Globus
Tour
 (5)

14 Days Rome to Palermo
Operated By: Globus
Departures: Jun 2026 to Nov 2027
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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US$4,049
Save 250
Per Person
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17 Day Grand Italy & Sicily with Insight Vacations
Tour
 (13)

17 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Jul 2026 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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Exclusive Savings
From
US$6,187
Save 845
Per Person
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14 Day Country Roads of Southern Italy & Sicily with Insight Vacations
Tour
 (8)

14 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Jul 2026 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
Sign Up Savings
Exclusive Savings
From
US$4,730
Save 755
Per Person
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10 Day Southern Italy and Sicily with Trafalgar
Tour
 (2)

10 Days Rome to Palermo
Operated By: Trafalgar
Departures: Jun 2026 to Oct 2027
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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Early Booking Offer
Exclusive Savings
From
US$3,262
Save 428
Per Person
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23 Day Rome to Sicily with Intrepid Travel
Tour

23 Days Rome to Palermo
Operated By: Intrepid Travel
Departures: Jul 2026 to Oct 2027
Trip Styles: Adventure, Small Group, Rail
Visit: Italy, Sicily
Exclusive Savings
From
US$7,136
Save 1,394
Per Person
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13 Day Italian Escape & Sicily with Contiki
Tour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Jul 2026 to Sep 2027
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$2,975
Save 380
Per Person
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13 Day Italian Escape & Sicily (Ages 27 to 35) with Contiki
Tour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2027
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$2,892
Save 483
Per Person
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22 Day Ultimate Italy with Contiki
Tour

22 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2027
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$4,530
Save 884
Per Person
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Results: 8 results

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Italy & Sicily

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10 Day 2 Week 7 Day

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June July August September October November March April May

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Tours from Rome

Popular Italy Operators

APT Italy Tours CIE Italy Tours Collette Italy Tours Cosmos Italy Tours Costsaver Italy Tours Exodus Italy Tours Explore's Italy Tours G Adventures Italy Tours Globus Italy Tours Insight Vacations Italy Tours Intrepid Italy Tours Trafalgar Italy Tours

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