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Tours from Rome to Palermo

Are you looking for a tour from Rome to Palermo? June is the most popular month to tour between Rome and Palermo and there are 133 departures available from five of the world's leading tour operators.
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11 Tours (133 Tour Departures)
17 Day Grand Italy & Sicily with Insight Vacations
Tour
 (13)

17 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Sep 2025 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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From
US$6,693
Save 1,073
Per Person
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14 Day Country Roads of Southern Italy & Sicily with Insight Vacations
Tour
 (8)

14 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Sep 2025 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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Exclusive Savings
From
US$4,807
Save 752
Per Person
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14 Day Highlights of Sicily & Southern Italy with Globus
Tour
 (5)

14 Days Rome to Palermo
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$3,919
Save 327
Per Person
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10 Day Southern Italy and Sicily with Trafalgar
Tour
 (2)

10 Days Rome to Palermo
Operated By: Trafalgar
Departures: Sep 2025 to Oct 2026
Trip Styles: Coach, Scenic
Visit: Italy, Sicily
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Early Booking Savings
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From
US$3,186
Save 476
Per Person
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13 Day Italian Escape & Sicily (Ages 27 to 35) with Contiki
New ReleaseTour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$2,791
Save 64
Per Person
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22 Day Ultimate Italy with Contiki
Tour

22 Days Rome to Palermo
Operated By: Contiki
Departures: Apr 2026 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$4,398
Save 117
Per Person
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13 Day Italian Escape & Sicily with Contiki
Tour

13 Days Rome to Palermo
Operated By: Contiki
Departures: Sep 2025 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$2,791
Save 262
Per Person
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14 Day Country Roads of Southern Italy & Sicily (Small Group) with Insight Vacations
Tour

14 Days Rome to Palermo
Operated By: Insight Vacations
Departure: 13 June 2026
Trip Styles: Coach, Small Group, Scenic
Visit: Italy, Sicily
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Exclusive Savings
From
US$6,111
Save 339
Per Person
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17 Day Grand Italy & Sicily (Small Group) with Insight Vacations
Tour

17 Days Rome to Palermo
Operated By: Insight Vacations
Departures: Apr 2026 to Aug 2026
Trip Styles: Coach, Small Group, Scenic
Visit: Italy, Sicily
Sign Up Savings
Exclusive Savings
From
US$8,051
Save 403
Per Person
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22 Day Ultimate Italy (Ages 27 to 35) with Contiki
Tour

22 Days Rome to Palermo
Operated By: Contiki
Departures: Jun 2026 to Sep 2026
Trip Styles: Coach, 18-30's, Scenic
Visit: Italy, Sicily
Exclusive Savings
From
US$4,823
Save 98
Per Person
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23 Day Rome to Sicily with Intrepid Travel
Tour

23 Days Rome to Palermo
Operated By: Intrepid Travel
Departures: Sep 2025 to Oct 2025
Trip Styles: Adventure, Small Group
Visit: Italy, Sicily
Exclusive Savings
From
US$8,281
Save 171
Per Person
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Results: 11 results

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Italy & Sicily

All Italy Tours Northern Italy Tours Sicily Tours Southern Italy Tours Tuscany Tours

Travel Styles

18-30's Tours Active Adventures Coach Tours Cycling Tours Family Holidays Food & Wine Tours Kayaking Trips Locally Guided Tours Luxury Tours Rail Journeys Religious Tours Short Breaks Small Group Tours Walking & Hiking Tours Winter Tours & Trips

Trip Lengths

10 Day 2 Week 7 Day

Departure Months

September 2025 October 2025 November 2025 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026

Countries

Croatia France Greece Italy Malta Monaco Sicily Slovenia Switzerland Turkey

Cities

Rome

Routes

Tours from Rome to Palermo

Popular Italy Operators

APT Italy Tours Collette Italy Tours Cosmos Italy Tours Costsaver Italy Tours Exodus Italy Tours Explore's Italy Tours G Adventures Italy Tours Globus Italy Tours Insight Vacations Italy Tours Intrepid Italy Tours Topdeck Italy Tours Trafalgar Italy Tours

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