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Midwest USA Tours Starting In April 2027 and 2028

Are you planning a tour through the US Midwest in April 2027 or 2028? Choose from 12 unique guided tours and adventures with 274 departures operated by US Midwest's leading tour operators. Easily compare prices, itineraries, inclusions and traveler reviews to find the US Midwest tour that best matches your travel style, budget and dates.
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12 Tours (274 Tour Departures)
10 Day Western Frontiers with Trafalgar
Tour

10 Days Las Vegas to Rapid City
Operated By: Trafalgar
Departures: May 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Exclusive Savings
From
US$4,345
Save 150
Per Person
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15 Day Exploring America's National Parks with Cosmos
Tour
 (26)

15 Days Las Vegas to Las Vegas
Operated By: Cosmos
Departures: Aug 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Exclusive Savings
From
US$3,449
Save 150
Per Person
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10 Day Rhythms of the Road with Cosmos
Tour
 (21)

10 Days Chicago to New Orleans
Operated By: Cosmos
Departures: May 2026 to Nov 2027
Trip Styles: Coach, Music Themed, Scenic
Visit: USA
Black Friday Sale
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From
US$2,529
Save 150
Per Person
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15 Day Scenic Parks Explorer with Trafalgar
Tour
 (21)

15 Days Las Vegas to Las Vegas
Operated By: Trafalgar
Departures: May 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Early Booking Offer
Exclusive Savings
From
US$6,435
Save 743
Per Person
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15 Day Exploring America's Great Parks with Globus
Tour
 (11)

15 Days Las Vegas to Las Vegas
Operated By: Globus
Departures: Jul 2026 to Sep 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Exclusive Savings
From
US$6,279
Save 250
Per Person
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9 Day American Parks Trail with Insight Vacations
Tour
 (6)

9 Days Salt Lake City to Denver
Operated By: Insight Vacations
Departures: Jun 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Exclusive Savings
From
US$4,545
Save 150
Per Person
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15 Day America's Magnificent National Parks with Insight Vacations
Tour
 (1)

15 Days Phoenix to Denver
Operated By: Insight Vacations
Departures: Jun 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Multiple Deals Available
From
US$7,820
Save 877
Per Person
View Trip
15 Day America's Magnificent National Parks with Insight Vacations
Tour
 (1)

15 Days Phoenix to Rapid City
Operated By: Insight Vacations
Departures: Jun 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Multiple Deals Available
From
US$7,820
Save 877
Per Person
View Trip
10 Day Western Frontiers with Trafalgar
Tour
 (1)

10 Days Las Vegas to Denver
Operated By: Trafalgar
Departures: May 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Exclusive Savings
From
US$4,345
Save 150
Per Person
View Trip
9 Day Mackinac Island featuring the Tulip Time Festival with Collette
Tour

9 Days Chicago to Detroit
Operated By: Collette
Departures: Apr 2027 to May 2027
Visit: USA
Flash Sale
Exclusive Savings
From
US$4,349
Save 250
Per Person
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9 Day Utah’s Mighty Five and The Rockies with Collette
Tour

9 Days Denver to Las Vegas
Operated By: Collette
Departures: Jun 2026 to Apr 2028
Trip Styles: Coach, Rail, Scenic, National Parks
Visit: USA
Flash Sale
Exclusive Savings
From
US$5,749
Save 250
Per Person
View Trip
9 Day American Parks Trail with Insight Vacations
Tour

9 Days Salt Lake City to Rapid City
Operated By: Insight Vacations
Departures: Jun 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Exclusive Savings
From
US$4,545
Save 150
Per Person
View Trip
Results: 12 results

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