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Midwest USA Tours Starting In April 2026 and 2027

Are you planning a tour through the US Midwest in April 2026 or 2027? Choose from 8 unique guided tours and adventures with 246 departures operated by US Midwest's leading tour operators. Easily compare prices, itineraries, inclusions and traveler reviews to find the US Midwest tour that best matches your travel style, budget and dates.
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8 Tours (246 Tour Departures)
15 Day Exploring America's National Parks with Cosmos
Tour
 (26)

15 Days Las Vegas to Las Vegas
Operated By: Cosmos
Departures: Apr 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
50% Off Single Supplement
Exclusive Savings
From
US$2,985
Save 374
Per Person
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10 Day Rhythms of the Road with Cosmos
Tour
 (21)

10 Days Chicago to New Orleans
Operated By: Cosmos
Departures: Apr 2026 to Nov 2027
Trip Styles: Coach, Music Themed, Scenic
Visit: USA
Black Friday Sale
Exclusive Savings
From
US$2,217
Save 342
Per Person
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15 Day Exploring America's Great Parks with Globus
Tour
 (11)

15 Days Las Vegas to Las Vegas
Operated By: Globus
Departures: Apr 2026 to Sep 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Exclusive Savings
From
US$5,567
Save 732
Per Person
View Trip
15 Day America's Magnificent National Parks with Insight Vacations
Tour
 (1)

15 Days Phoenix to Denver
Operated By: Insight Vacations
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Exclusive Savings
From
US$7,805
Save 478
Per Person
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10 Day Western Frontiers with Trafalgar
Tour
 (1)

10 Days Las Vegas to Denver
Operated By: Trafalgar
Departures: Apr 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Big Travel Sale
Exclusive Savings
From
US$3,759
Save 713
Per Person
View Trip
9 Day Utah’s Mighty Five and The Rockies with Collette
Tour

9 Days Denver to Las Vegas
Operated By: Collette
Departures: May 2026 to Apr 2027
Trip Styles: Coach, Rail, Scenic, National Parks
Visit: USA
New Year Sale
Exclusive Savings
From
US$5,279
Save 620
Per Person
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9 Day Mackinac Island (Tulip Time Festival) with Collette
Tour

9 Days Chicago to Southfield
Operated By: Collette
Departures: Apr 2026 to May 2026
Visit: USA
New Year Sale
Exclusive Savings
From
US$3,599
Save 408
Per Person
View Trip
10 Day Western Frontiers with Trafalgar
Tour

10 Days Las Vegas to Rapid City
Operated By: Trafalgar
Departures: Apr 2026 to Oct 2027
Trip Styles: Coach, Scenic, National Parks
Visit: USA
Sign Up Savings
Big Travel Sale
Exclusive Savings
From
US$3,759
Save 713
Per Person
View Trip
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