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All Main River Cruises

The Main river flows through Germany from modern, densely populated Mainz to more traditional medieval Bavarian towns lined with lovely forests and small towns and dotted with hilltop castles and churches. Choose from 2,277 river cruises along the Main travelling with the world's leading river cruise lines.
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219 River Cruises (2,277 Departures)
219 River Cruises (2,277 Departures)
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Duration
6 Days
46 Days
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$3,900pp
$64,550pp
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15 Day Magnificent Europe with Avalon River Cruises Featured
River CruiseFlights Included
 (81)

15 Days Amsterdam to Budapest
Operator: Avalon
Ships: Avalon Expression, Avalon Illumination +2 more, Avalon Impression, Avalon Passion
Departures: May 2027 to Oct 2028
Rivers: Rhine, Main, Danube
Visits: Holland, Germany, Austria, Hungary
Exclusive Savings
River View
$8,055
Balcony
$12,274
Suite
$16,299
From (Per Person)
A$8,055
Save 2,764
Per Person
View Trip
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise
 (2)

6 Days Frankfurt to Nuremberg
Operator: Avalon
Ship: Avalon Tranquility II
Departure: 06 December 2026
Rivers: Main
Visits: Germany
Exclusive Savings
Balcony
$6,077
From (Per Person)
A$4,484
Save 750
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Operator: Uniworld
Ships: S.S. Elisabeth, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$7,749
Balcony
$9,316
Suite
$11,766
From (Per Person)
A$7,749
Save 293
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Prague to Frankfurt
Operator: Avalon
Ships: Avalon Illumination, Avalon Tranquility II +4 more, Avalon Passion, Avalon Vista, Avalon Impression, Avalon View
Departures: Dec 2026 to Dec 2028
Rivers: Main
Visits: Czech Republic, Germany
Exclusive Savings
River View
$6,228
Balcony
$7,092
Suite
$8,999
From (Per Person)
A$5,568
Save 783
Per Person
View Trip
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise

6 Days Nuremberg to Frankfurt
Operator: Avalon
Ships: Avalon Illumination, Avalon Tranquility II
Departures: Dec 2026
Rivers: Main
Visits: Germany
Exclusive Savings
Balcony
$6,008
From (Per Person)
A$4,484
Save 750
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Frankfurt to Nuremberg
Operator: Avalon
Ships: Avalon Expression, Avalon Panorama +4 more, Avalon Passion, Avalon Vista, Avalon Envision, Avalon View
Departures: Nov 2027 to Dec 2028
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$4,853
Balcony
$6,376
Suite
$7,624
From (Per Person)
A$4,853
Save 836
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Frankfurt to Prague
Operator: Avalon
Ships: Avalon Tranquility II, Avalon Expression +5 more, Avalon Panorama, Avalon Passion, Avalon Vista, Avalon Envision, Avalon View
Departures: Dec 2026 to Dec 2028
Rivers: Main
Visits: Germany, Czech Republic
Exclusive Savings
River View
$5,958
Balcony
$7,161
Suite
$8,729
From (Per Person)
A$5,568
Save 870
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Nuremberg to Frankfurt
Operator: Avalon
Ships: Avalon Passion, Avalon Vista +3 more, Avalon Illumination, Avalon Impression, Avalon View
Departures: Dec 2027 to Dec 2028
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$5,174
Balcony
$6,698
Suite
$7,945
From (Per Person)
A$5,174
Save 497
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Operator: Uniworld
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$8,239
Balcony
$9,415
Suite
$14,657
From (Per Person)
A$8,239
Save 256
Per Person
View Trip
9 Day German Grandeur (Eastbound) with Avalon River Cruises
River Cruise
 (1)

9 Days Basel to Nuremberg
Operator: Avalon
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: May 2027 to May 2028
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$5,839
Balcony
$8,278
Suite
$10,273
From (Per Person)
A$5,839
Save 1,959
Per Person
View Trip
9 Day German Grandeur (Westbound) with Avalon River Cruises
New ReleaseRiver Cruise
 (1)

9 Days Nuremberg to Basel
Operator: Avalon
Ship: Avalon Visionary
Departure: 04 September 2028
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$6,393
Balcony
$8,832
Suite
$10,827
From (Per Person)
A$6,393
Save 1,577
Per Person
View Trip
11 Day German Grandeur with Munich (Eastbound) with Avalon River Cruises
River Cruise
 (1)

11 Days Basel to Munich
Operator: Avalon
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: May 2027 to May 2028
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$7,235
Balcony
$9,674
Suite
$11,669
From (Per Person)
A$7,235
Save 2,002
Per Person
View Trip
8 Day Rhine & Main River Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Operator: Celebrity Cruises
Ship: Celebrity Compass
Departure: 11 May 2028
Rivers: Rhine, Main
Visits: Holland, Germany
Exclusive Savings
River View
$6,924
Balcony
$9,784
Suite
-
From (Per Person)
A$6,924
Save 4,525
Per Person
View Trip
11 Day German Grandeur with Munich (Westbound) with Avalon River Cruises
New ReleaseRiver Cruise

11 Days Munich to Basel
Operator: Avalon
Ship: Avalon Visionary
Departure: 02 September 2028
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$7,724
Balcony
$10,163
Suite
$12,158
From (Per Person)
A$7,724
Save 1,618
Per Person
View Trip
8 Day Medieval Treasures (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Operator: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Aug 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Bonus $300 Onboard Credit
Exclusive Savings
River View
$4,739
Balcony
$6,971
Suite
$10,600
From (Per Person)
A$4,739
Save 1,644
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Operator: Viking
Ships: Viking Eldir, Viking Kvasir, Viking Skirnir
Departures: Nov 2027
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$9,599
Balcony
$11,069
Suite
$16,263
From (Per Person)
A$9,599
Save 196
Per Person
View Trip
8 Day Three-Rivers Cruise with Amadeus River Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Operator: Amadeus
Ships: Amadeus Amara, Amadeus Cara
Departures: May 2027 to Aug 2027
Rivers: Rhine, Main
Visits: Holland, Germany
Exclusive Savings
Inside
-
River View
$4,094
Balcony
$5,841
Suite
$7,558
From (Per Person)
A$4,094
Save 234
Per Person
View Trip
11 Day German Grandeur with Lucerne (Eastbound) with Avalon River Cruises
New ReleaseRiver Cruise

11 Days Lucerne to Nuremberg
Operator: Avalon
Ship: Avalon Tranquility II
Departure: 12 May 2028
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$8,580
Balcony
$11,018
Suite
$13,014
From (Per Person)
A$8,580
Save 1,119
Per Person
View Trip
8 Day Main & Rhine Christmas Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Basel
Operator: Celebrity Cruises
Ships: Celebrity Compass, Celebrity Seeker
Departures: Dec 2027 to Dec 2028
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$6,098
Balcony
$7,341
Suite
$12,528
From (Per Person)
A$6,098
Save 5,474
Per Person
View Trip
12 Day Christmastime from Basel to Nuremberg with Prague with Avalon River Cruises
River Cruise

12 Days Basel to Prague
Operator: Avalon
Ships: Avalon Expression, Avalon Panorama +2 more, Avalon Envision, Avalon View
Departures: Nov 2027 to Dec 2028
Rivers: Rhine, Main
Visits: Switzerland, France, Germany, Czech Republic
Exclusive Savings
River View
$10,643
Balcony
$13,386
Suite
$16,397
From (Per Person)
A$10,643
Save 1,179
Per Person
View Trip
13 Day German Grandeur with Lucerne & Munich (Eastbound) with Avalon River Cruises
New ReleaseRiver Cruise

13 Days Lucerne to Munich
Operator: Avalon
Ship: Avalon Tranquility II
Departure: 12 May 2028
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$9,910
Balcony
$12,349
Suite
$14,344
From (Per Person)
A$9,910
Save 1,160
Per Person
View Trip
12 Day Christmastime from Nuremberg to Basel with Prague with Avalon River Cruises
River Cruise

12 Days Prague to Basel
Operator: Avalon
Ships: Avalon Vista, Avalon View
Departures: Dec 2027 to Dec 2028
Rivers: Main, Rhine
Visits: Czech Republic, Germany, France, Switzerland
Exclusive Savings
River View
$10,812
Balcony
$13,555
Suite
$16,057
From (Per Person)
A$10,812
Save 1,010
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Operator: Viking
Ships: Viking Modi, Viking Skirnir
Departures: Oct 2026 to Nov 2027
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$4,699
Balcony
$6,561
Suite
$12,735
From (Per Person)
A$4,699
Save 2,610
Per Person
View Trip
11 Day German Grandeur with Lucerne (Westbound) with Avalon River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Lucerne
Operator: Avalon
Ship: Avalon Visionary
Departure: 04 September 2028
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$8,071
Balcony
$10,509
Suite
$12,504
From (Per Person)
A$8,071
Save 1,628
Per Person
View Trip
13 Day German Grandeur with Munich & Lucerne (Westbound) with Avalon River Cruises
New ReleaseRiver Cruise

13 Days Munich to Lucerne
Operator: Avalon
Ship: Avalon Visionary
Departure: 02 September 2028
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$9,401
Balcony
$11,839
Suite
$13,835
From (Per Person)
A$9,401
Save 1,669
Per Person
View Trip
10 Day Christmastime from Nuremberg to Basel with Avalon River Cruises
River Cruise

10 Days Nuremberg to Basel
Operator: Avalon
Ships: Avalon Vista, Avalon View
Departures: Dec 2027 to Dec 2028
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$9,708
Balcony
$12,451
Suite
$15,004
From (Per Person)
A$9,708
Save 976
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Operator: Viking
Ships: Viking Modi, Viking Skirnir
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$4,699
Balcony
$7,247
Suite
$13,323
From (Per Person)
A$4,699
Save 2,596
Per Person
View Trip
8 Day Medieval Treasures with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Operator: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Apr 2027 to Nov 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Bonus $300 Onboard Credit
Exclusive Savings
River View
$4,518
Balcony
$6,680
Suite
$10,309
From (Per Person)
A$4,518
Save 1,952
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Operator: Viking
Ships: Viking Eldir, Viking Kvasir +2 more, Viking Modi, Viking Skirnir
Departures: Nov 2027 to Dec 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$9,599
Balcony
$11,069
Suite
$16,263
From (Per Person)
A$9,599
Save 212
Per Person
View Trip
10 Day Christmastime from Basel to Nuremberg with Avalon River Cruises
River Cruise

10 Days Basel to Nuremberg
Operator: Avalon
Ships: Avalon Expression, Avalon Panorama +2 more, Avalon Envision, Avalon View
Departures: Nov 2027 to Dec 2028
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$9,538
Balcony
$12,281
Suite
$15,344
From (Per Person)
A$9,538
Save 1,146
Per Person
View Trip
Results: 1-29 of 219

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