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All Main River Cruises

The Main river flows through Germany from modern, densely populated Mainz to more traditional medieval Bavarian towns lined with lovely forests and small towns and dotted with hilltop castles and churches. Choose from 2,288 river cruises along the Main travelling with the world's leading river cruise lines.
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207 River Cruises (2,288 Departures)
207 River Cruises (2,288 Departures)
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Duration
6 Days
35 Days
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Price
$2,700pp
$37,195pp
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23 Day European Sojourn with Viking River Cruises Featured
River Cruise
 (1)

23 Days Amsterdam to Bucharest
Operator: Viking
Ships: Viking Eldir, Viking Lif, Viking Vidar
Departures: Jun 2027 to Oct 2028
Rivers: Rhine, Main, Danube
Visits: Holland, Germany, Austria, Hungary +4 more, Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
River View
$16,263
Balcony
$19,203
Suite
$36,059
From (Per Person)
A$16,263
Save 400
Per Person
View Trip
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise
 (2)

6 Days Frankfurt to Nuremberg
Operator: Avalon
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: Dec 2026
Rivers: Main
Visits: Germany
Exclusive Savings
River View
-
Balcony
$6,008
Suite
-
From (Per Person)
A$4,484
Save 750
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Frankfurt to Nuremberg
Operator: Avalon
Ships: Avalon Expression, Avalon Panorama +2 more, Avalon Passion, Avalon Vista
Departures: Nov 2027 to Dec 2027
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$4,853
Balcony
$6,376
Suite
$7,624
From (Per Person)
A$4,853
Save 836
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Prague to Frankfurt
Operator: Avalon
Ships: Avalon Illumination, Avalon Passion, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visits: Czech Republic, Germany
Exclusive Savings
River View
$5,568
Balcony
$7,092
Suite
$9,069
From (Per Person)
A$5,568
Save 783
Per Person
View Trip
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise

6 Days Nuremberg to Frankfurt
Operator: Avalon
Ship: Avalon Illumination
Departure: 13 December 2026
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$4,484
Balcony
$6,008
From (Per Person)
A$4,484
Save 750
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Nuremberg to Frankfurt
Operator: Avalon
Ships: Avalon Passion, Avalon Vista
Departures: Dec 2027
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$5,192
Balcony
$6,716
Suite
$7,963
From (Per Person)
A$5,192
Save 497
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Operator: Uniworld
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$5,789
Balcony
$7,455
Suite
$9,806
From (Per Person)
A$5,789
Save 2,241
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Frankfurt to Prague
Operator: Avalon
Ships: Avalon Expression, Avalon Imagery II +4 more, Avalon Panorama, Avalon Passion, Avalon Tranquility II, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visits: Germany, Czech Republic
Exclusive Savings
River View
$5,958
Balcony
$7,092
Suite
$8,729
From (Per Person)
A$5,568
Save 870
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Operator: Uniworld
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visits: Germany
Exclusive Savings
River View
$5,789
Balcony
$7,455
Suite
$12,697
From (Per Person)
A$5,789
Save 2,196
Per Person
View Trip
9 Day German Grandeur (Eastbound) with Avalon River Cruises
River Cruise
 (1)

9 Days Basel to Nuremberg
Operator: Avalon
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: May 2027 to Oct 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$5,839
Balcony
$8,278
Suite
$10,273
From (Per Person)
A$5,839
Save 1,959
Per Person
View Trip
11 Day German Grandeur with Munich (Eastbound) with Avalon River Cruises
River Cruise
 (1)

11 Days Basel to Munich
Operator: Avalon
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: May 2027 to Oct 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$7,235
Balcony
$9,674
Suite
$11,669
From (Per Person)
A$7,235
Save 2,002
Per Person
View Trip
7 Day Magic of Advent on the Rhine and Main with Amadeus River Cruises
New ReleaseRiver Cruise
 (1)

7 Days Strasbourg to Nuremberg
Operator: Amadeus
Ship: Amadeus Nova
Departure: 08 December 2027
Rivers: Rhine, Main
Visits: France, Germany
Exclusive Savings
Inside
-
River View
$2,727
Balcony
$3,565
Suite
-
From (Per Person)
A$2,727
Save 206
Per Person
View Trip
10 Day Christmastime from Basel to Nuremberg with Avalon River Cruises
River Cruise

10 Days Basel to Nuremberg
Operator: Avalon
Ships: Avalon Expression, Avalon Panorama, Avalon Vista
Departures: Nov 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$9,538
Balcony
$12,281
Suite
-
From (Per Person)
A$9,538
Save 1,146
Per Person
View Trip
8 Day Three-Rivers Cruise with Amadeus River Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Operator: Amadeus
Ships: Amadeus Amara, Amadeus Cara, Amadeus Mira
Departures: May 2027 to Aug 2027
Rivers: Rhine, Main
Visits: Holland, Germany
Exclusive Savings
Inside
-
River View
$4,094
Balcony
$5,408
Suite
$7,558
From (Per Person)
A$4,094
Save 234
Per Person
View Trip
12 Day Christmastime from Nuremberg to Basel with Prague with Avalon River Cruises
River Cruise

12 Days Prague to Basel
Operator: Avalon
Ship: Avalon Vista
Departure: 07 December 2027
Rivers: Main, Rhine
Visits: Czech Republic, Germany, France, Switzerland
Exclusive Savings
River View
$10,812
Balcony
$13,555
Suite
-
From (Per Person)
A$10,812
Save 1,010
Per Person
View Trip
12 Day Christmastime from Basel to Nuremberg with Prague with Avalon River Cruises
River Cruise

12 Days Basel to Prague
Operator: Avalon
Ships: Avalon Expression, Avalon Panorama, Avalon Vista
Departures: Nov 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany, Czech Republic
Exclusive Savings
River View
$10,643
Balcony
$13,386
Suite
-
From (Per Person)
A$10,643
Save 1,179
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Operator: Viking
Ships: Viking Modi, Viking Skirnir
Departures: Aug 2026 to Nov 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$4,699
Balcony
$6,757
Suite
$13,323
From (Per Person)
A$4,699
Save 2,632
Per Person
View Trip
8 Day Medieval Treasures (Wine Cruise) with AmaWaterways
New ReleaseRiver CruiseFlights Included

8 Days Basel to Nuremberg
Operator: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Aug 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$8,619
Balcony
$10,851
Suite
$14,480
From (Per Person)
A$8,619
Save 264
Per Person
View Trip
8 Day Highlights of the Rhine and Main with APT
River Cruise

8 Days Amsterdam to Munich
Operator: APT
Ships: APT Solara, APT Ostara
Departures: Nov 2026 to Dec 2028
Rivers: Rhine, Main
Visits: Holland, Germany
Exclusive Savings
River View
$3,930
Balcony
$5,743
Suite
$9,222
From (Per Person)
A$3,930
Save 1,819
Per Person
View Trip
10 Day Christmastime from Nuremberg to Basel with Avalon River Cruises
River Cruise

10 Days Nuremberg to Basel
Operator: Avalon
Ship: Avalon Vista
Departure: 09 December 2027
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$9,708
Balcony
$12,451
Suite
-
From (Per Person)
A$9,708
Save 976
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Operator: Viking
Ships: Viking Modi, Viking Skirnir
Departures: Nov 2026 to Nov 2027
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$4,699
Balcony
$6,561
Suite
$13,323
From (Per Person)
A$4,699
Save 2,602
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Operator: Viking
Ships: Viking Eldir, Viking Kvasir +2 more, Viking Modi, Viking Skirnir
Departures: Dec 2026 to Dec 2027
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$6,463
Balcony
$9,109
Suite
$16,263
From (Per Person)
A$6,463
Save 2,632
Per Person
View Trip
8 Day Medieval Treasures with AmaWaterways
New ReleaseRiver CruiseFlights Included

8 Days Basel to Nuremberg
Operator: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Apr 2027 to Nov 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$5,801
Balcony
$7,963
Suite
$11,885
From (Per Person)
A$5,801
Save 1,284
Per Person
View Trip
8 Day Rhine & Main River Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Operator: Celebrity Cruises
Ship: Celebrity Compass
Departure: 11 May 2028
Rivers: Rhine, Main
Visits: Holland, Germany
Exclusive Savings
River View
$6,924
Balcony
$9,649
Suite
-
From (Per Person)
A$6,924
Save 4,525
Per Person
View Trip
8 Day Main & Rhine Christmas Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Basel
Operator: Celebrity Cruises
Ships: Celebrity Compass, Celebrity Seeker
Departures: Dec 2027 to Dec 2028
Rivers: Main, Rhine
Visits: Germany, France, Switzerland
Exclusive Savings
River View
$6,098
Balcony
$7,341
Suite
$12,528
From (Per Person)
A$6,098
Save 9,682
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Operator: Viking
Ships: Viking Eldir, Viking Kvasir +2 more, Viking Modi, Viking Skirnir
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main
Visits: Switzerland, France, Germany
Exclusive Savings
River View
$6,463
Balcony
$11,069
From (Per Person)
A$6,463
Save 2,632
Per Person
View Trip
12 Day Christmastime from Frankfurt to Vienna with Avalon River Cruises
River Cruise

12 Days Frankfurt to Vienna
Operator: Avalon
Ships: Avalon Tranquility II, Avalon Vista +2 more, Avalon Expression, Avalon Imagery II
Departures: Dec 2026 to Dec 2027
Rivers: Main, Danube
Visits: Germany, Austria
Exclusive Savings
River View
$11,191
Balcony
$13,278
From (Per Person)
A$9,772
Save 1,573
Per Person
View Trip
13 Day Christmastime from Frankfurt to Budapest with Avalon River Cruises
River Cruise

13 Days Frankfurt to Budapest
Operator: Avalon
Ship: Avalon Panorama
Departure: 01 December 2027
Rivers: Main, Danube
Visits: Germany, Austria, Hungary
Exclusive Savings
River View
$12,769
From (Per Person)
A$12,769
Save 573
Per Person
View Trip
9 Day Christmastime on the Danube with Prague (Eastbound) with Avalon River Cruises
River Cruise

9 Days Prague to Vienna
Operator: Avalon
Ships: Avalon Expression, Avalon Imagery II +5 more, Avalon Impression, Avalon Passion, Avalon Tranquility II, Avalon Visionary, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main, Danube
Visits: Czech Republic, Germany, Austria
Exclusive Savings
River View
$6,210
Balcony
$7,602
Suite
$9,562
From (Per Person)
A$5,774
Save 1,462
Per Person
View Trip
13 Day Christmastime from Budapest to Frankfurt with Avalon River Cruises
River Cruise

13 Days Budapest to Frankfurt
Operator: Avalon
Ship: Avalon Passion
Departure: 29 November 2027
Rivers: Danube, Main
Visits: Hungary, Austria, Germany
Exclusive Savings
River View
-
Balcony
$16,630
Suite
-
From (Per Person)
A$12,973
Save 369
Per Person
View Trip
Results: 1-29 of 207

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