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All Main River Cruises

The Main river flows through Germany from modern, densely populated Mainz to more traditional medieval Bavarian towns lined with lovely forests and small towns and dotted with hilltop castles and churches. Choose from 1,923 river cruises along the Main travelling with the world's leading river cruise lines.
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202 River Cruises (1,923 River Cruise Departures)
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise
 (2)

6 Days Frankfurt to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
-
Balcony
$6,008
Suite
-
From
A$4,484
Save 750
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Frankfurt to Prague
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Imagery II (+4 more), Avalon Panorama, Avalon Passion, Avalon Tranquility II, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany, Czech Republic
Exclusive Savings
Inside
-
River View
$5,958
Balcony
$7,092
Suite
$8,729
From
A$5,568
Save 870
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Germany
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,201
Balcony
$7,533
Suite
$11,924
From
A$6,201
Save 1,731
Per Person
View Trip
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise

6 Days Nuremberg to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Imagery II, Avalon Tranquility II
Departures: Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,484
Balcony
$6,077
Suite
-
From
A$4,484
Save 750
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Prague to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Imagery II (+3 more), Avalon Tranquility II, Avalon Passion, Avalon Vista
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Czech Republic, Germany
Exclusive Savings
Inside
-
River View
$5,568
Balcony
$7,161
Suite
$9,069
From
A$5,568
Save 783
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Nuremberg to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Passion, Avalon Vista
Departures: Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$5,192
Balcony
$6,716
Suite
$7,963
From
A$5,192
Save 497
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Frankfurt to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Panorama (+2 more), Avalon Passion, Avalon Vista
Departures: Nov 2027 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,853
Balcony
$6,376
Suite
$7,624
From
A$4,853
Save 836
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,201
Balcony
$7,533
Suite
$11,924
From
A$6,201
Save 1,796
Per Person
View Trip
9 Day German Grandeur (Eastbound) with Avalon River Cruises
River Cruise
 (1)

9 Days Basel to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: May 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$5,839
Balcony
$8,278
Suite
$10,273
From
A$5,839
Save 1,959
Per Person
View Trip
11 Day German Grandeur with Munich (Eastbound) with Avalon River Cruises
River Cruise
 (1)

11 Days Basel to Munich
Cruise Line: Avalon River Cruises
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: May 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$7,235
Balcony
$9,674
Suite
$11,669
From
A$7,235
Save 2,002
Per Person
View Trip
7 Day Magic of Advent on the Rhine and Main with Amadeus River Cruises
New ReleaseRiver Cruise
 (1)

7 Days Strasbourg to Nuremberg
Cruise Line: Amadeus River Cruises
Ship: Amadeus Nova
Departure: 08 December 2027
Rivers: Rhine, Main
Visit: France, Germany
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$4,905
From
A$4,905
Save 250
Per Person
View Trip
8 Day Rhine & Main River Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Cruise Line: Celebrity Cruises
Ship: Celebrity Compass
Departure: 11 May 2028
Rivers: Rhine, Main
Visit: Holland, Germany
Exclusive Savings
Inside
-
River View
$6,924
Balcony
$9,207
Suite
-
From
A$6,924
Save 4,525
Per Person
View Trip
8 Day Three-Rivers Cruise with Amadeus River Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Cruise Line: Amadeus River Cruises
Ships: Amadeus Amara, Amadeus Cara, Amadeus Mira
Departures: May 2027 to Aug 2027
Rivers: Rhine, Main
Visit: Holland, Germany
Exclusive Savings
Inside
-
River View
$4,094
Balcony
$5,408
Suite
$7,558
From
A$4,094
Save 234
Per Person
View Trip
10 Day Christmastime from Basel to Nuremberg with Avalon River Cruises
River Cruise

10 Days Basel to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Panorama, Avalon Vista
Departures: Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$9,708
Balcony
$12,451
Suite
$15,172
From
A$9,708
Save 976
Per Person
View Trip
8 Day Main & Rhine Christmas Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Basel
Cruise Line: Celebrity Cruises
Ships: Celebrity Compass, Celebrity Seeker
Departures: Dec 2027 to Dec 2028
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$5,614
Balcony
$7,341
Suite
$11,370
From
A$5,614
Save 9,682
Per Person
View Trip
8 Day Medieval Treasures with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Cruise and Fly
Exclusive Savings
Inside
-
River View
$6,571
Balcony
$8,975
Suite
$13,296
From
A$6,571
Save 1,307
Per Person
View Trip
8 Day Highlights of the Rhine and Main with APT
River Cruise

8 Days Amsterdam to Munich
Cruise Line: APT
Ships: APT Ostara, APT Solara
Departures: Jun 2026 to Dec 2027
Rivers: Rhine, Main
Visit: Holland, Germany
Early Booking Savings
Exclusive Savings
Inside
-
River View
$4,126
Balcony
$5,939
Suite
$9,222
From
A$4,126
Save 1,814
Per Person
View Trip
12 Day Christmastime from Basel to Nuremberg with Prague with Avalon River Cruises
River Cruise

12 Days Basel to Prague
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Panorama, Avalon Vista
Departures: Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany, Czech Republic
Exclusive Savings
Inside
-
River View
$10,812
Balcony
$13,555
Suite
$16,276
From
A$10,812
Save 1,010
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Viking Savings Event
Exclusive Savings
Inside
-
River View
$4,699
Balcony
$5,875
Suite
$10,579
From
A$4,699
Save 2,658
Per Person
View Trip
8 Day Medieval Treasures (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Aug 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Cruise and Fly
Exclusive Savings
Inside
-
River View
$9,311
Balcony
$11,793
Suite
$15,828
From
A$9,311
Save 286
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Cruise Line: Viking River Cruises
Ships: Viking Eldir, Viking Kvasir (+2 more), Viking Modi, Viking Skirnir
Departures: Nov 2026 to Dec 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Viking Savings Event
Exclusive Savings
Inside
-
River View
$6,463
Balcony
$8,325
Suite
$13,519
From
A$6,463
Save 2,712
Per Person
View Trip
12 Day Christmastime from Nuremberg to Basel with Prague with Avalon River Cruises
River Cruise

12 Days Prague to Basel
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Tranquility II, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main, Rhine
Visit: Czech Republic, Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$10,812
Balcony
$11,907
Suite
$15,801
From
A$8,977
Save 1,953
Per Person
View Trip
10 Day Christmastime from Nuremberg to Basel with Avalon River Cruises
River Cruise

10 Days Nuremberg to Basel
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Tranquility II, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$9,708
Balcony
$10,823
Suite
$14,697
From
A$7,893
Save 1,920
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: Jun 2026 to Nov 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Viking Savings Event
Exclusive Savings
Inside
-
River View
$4,699
Balcony
$5,875
Suite
$10,579
From
A$4,699
Save 2,644
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Ships: Viking Eldir, Viking Kvasir (+2 more), Viking Modi, Viking Skirnir
Departures: Nov 2026 to Dec 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Viking Savings Event
Exclusive Savings
Inside
-
River View
$6,463
Balcony
$8,325
Suite
$13,519
From
A$6,463
Save 2,776
Per Person
View Trip
8 Day Three-Rivers Cruise with Amadeus River Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Amsterdam
Cruise Line: Amadeus River Cruises
Ship: Amadeus Aurea
Departure: 21 July 2026
Rivers: Main, Rhine
Visit: Germany, Holland
Exclusive Savings
Inside
-
River View
-
Balcony
$5,772
Suite
$7,340
From
A$5,772
Save 118
Per Person
View Trip
12 Day Christmastime from Frankfurt to Vienna with Avalon River Cruises
River Cruise

12 Days Frankfurt to Vienna
Cruise Line: Avalon River Cruises
Ships: Avalon Tranquility II, Avalon Vista (+2 more), Avalon Expression, Avalon Imagery II
Departures: Dec 2026 to Dec 2027
Rivers: Main, Danube
Visit: Germany, Austria
Exclusive Savings
Inside
-
River View
$11,191
Balcony
$13,278
Suite
-
From
A$9,772
Save 1,573
Per Person
View Trip
12 Day Christmastime from Vienna to Frankfurt with Avalon River Cruises
River Cruise

12 Days Vienna to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Imagery II, Avalon Vista
Departure: 03 December 2027
Rivers: Danube, Main
Visit: Austria, Germany
Exclusive Savings
Inside
-
River View
$11,530
Balcony
$14,882
Suite
-
From
A$11,530
Save 677
Per Person
View Trip
13 Day Christmastime from Frankfurt to Budapest with Avalon River Cruises
River Cruise

13 Days Frankfurt to Budapest
Cruise Line: Avalon River Cruises
Ship: Avalon Panorama
Departure: 01 December 2027
Rivers: Main, Danube
Visit: Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$12,769
Balcony
$16,676
Suite
$19,421
From
A$12,769
Save 573
Per Person
View Trip
9 Day Christmastime on the Danube with Prague (Eastbound) with Avalon River Cruises
River Cruise

9 Days Prague to Vienna
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Imagery II (+5 more), Avalon Impression, Avalon Passion, Avalon Tranquility II, Avalon Visionary, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main, Danube
Visit: Czech Republic, Germany, Austria
Exclusive Savings
Inside
-
River View
$6,237
Balcony
$7,602
Suite
$9,562
From
A$5,774
Save 1,462
Per Person
View Trip
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