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All Main River Cruises

The Main river flows through Germany from modern, densely populated Mainz to more traditional medieval Bavarian towns lined with lovely forests and small towns and dotted with hilltop castles and churches. Choose from 1,592 river cruises along the Main traveling with the world's leading river cruise lines.
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143 River Cruises (1,592 River Cruise Departures)
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise
 (2)

6 Days Frankfurt to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Imagery II, Avalon Tranquility II
Departures: Dec 2026 to Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
-
Balcony
$4,217
Suite
-
From
US$2,789
Save 375
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$8,819
From
US$4,589
Save 510
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$7,799
From
US$4,589
Save 540
Per Person
View Trip
6 Day Festive Season in the Heart of Germany with Avalon River Cruises
River Cruise

6 Days Nuremberg to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Tranquility II
Departures: Dec 2026 to Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
-
Balcony
$4,217
Suite
-
From
US$2,789
Save 375
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Frankfurt to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Panorama (+2 more), Avalon Passion, Avalon Vista
Departures: Nov 2027 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$3,304
Balcony
$4,804
Suite
$6,089
From
US$3,304
Save 375
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Prague to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Tranquility II (+2 more), Avalon Passion, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Czech Republic, Germany
Exclusive Savings
Inside
-
River View
$4,178
Balcony
$4,906
Suite
$6,963
From
US$3,478
Save 375
Per Person
View Trip
6 Day Christmastime in the Heart of Germany with Avalon River Cruises
New ReleaseRiver Cruise

6 Days Nuremberg to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Passion, Avalon Vista
Departures: Dec 2027 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$3,429
Balcony
$4,929
Suite
$6,214
From
US$3,429
Save 250
Per Person
View Trip
8 Day Festive Season in the Heart of Germany with Prague with Avalon River Cruises
River Cruise

8 Days Frankfurt to Prague
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Imagery II (+4 more), Avalon Panorama, Avalon Passion, Avalon Tranquility II, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany, Czech Republic
Exclusive Savings
Inside
-
River View
$4,053
Balcony
$4,906
Suite
$6,838
From
US$3,478
Save 375
Per Person
View Trip
9 Day German Grandeur (Eastbound) with Avalon River Cruises
River Cruise
 (1)

9 Days Basel to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Tranquility II, Avalon Imagery II
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$4,837
Balcony
$7,234
Suite
$9,843
From
US$4,837
Save 750
Per Person
View Trip
11 Day German Grandeur with Munich (Eastbound) with Avalon River Cruises
River Cruise
 (1)

11 Days Basel to Munich
Cruise Line: Avalon River Cruises
Ships: Avalon Tranquility II, Avalon Imagery II
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$5,786
Balcony
$8,113
Suite
$10,792
From
US$5,786
Save 750
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Ships: Viking Eldir, Viking Kvasir (+2 more), Viking Modi, Viking Skirnir
Departures: Nov 2026 to Dec 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Viking $999 Air Deal
Exclusive Savings
Inside
-
River View
$4,499
Balcony
$5,599
Suite
$8,999
From
US$4,499
Save 100
Per Person
View Trip
8 Day Medieval Treasures with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,279
Balcony
$4,878
Suite
$7,478
From
US$3,279
Save 1,250
Per Person
View Trip
8 Day Three-Rivers Cruise with Amadeus River Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Cruise Line: Amadeus River Cruises
Ships: Amadeus Cara, Amadeus Amara, Amadeus Mira
Departures: May 2026 to Aug 2027
Rivers: Rhine, Main
Visit: Holland, Germany
Exclusive Savings
Inside
-
River View
$3,038
Balcony
$3,711
Suite
$5,519
From
US$2,888
Save 150
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Multiple Deals Available
Inside
-
River View
$3,199
Balcony
$3,799
Suite
$5,499
From
US$3,199
Save 500
Per Person
View Trip
8 Day Three-Rivers Cruise with Amadeus River Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Amsterdam
Cruise Line: Amadeus River Cruises
Ship: Amadeus Aurea
Departure: 21 July 2026
Rivers: Main, Rhine
Visit: Germany, Holland
Inside
-
River View
-
Balcony
-
Suite
$5,078
From
US$5,078
Per Person
View Trip
12 Day Christmastime from Nuremberg to Basel with Prague with Avalon River Cruises
River Cruise

12 Days Prague to Basel
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Tranquility II, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main, Rhine
Visit: Czech Republic, Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$7,296
Balcony
$8,519
Suite
$12,309
From
US$5,884
Save 750
Per Person
View Trip
12 Day Christmastime from Basel to Nuremberg with Prague with Avalon River Cruises
River Cruise

12 Days Basel to Prague
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Panorama, Avalon Vista
Departures: Nov 2027 to Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany, Czech Republic
Exclusive Savings
Inside
-
River View
$7,046
Balcony
$9,746
Suite
$12,534
From
US$7,046
Save 625
Per Person
View Trip
8 Day Medieval Treasures (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Aug 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,679
Balcony
$5,278
Suite
$7,878
From
US$3,679
Save 1,250
Per Person
View Trip
10 Day Christmastime from Basel to Nuremberg with Avalon River Cruises
River Cruise

10 Days Basel to Nuremberg
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Panorama, Avalon Vista
Departures: Nov 2027 to Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$6,297
Balcony
$8,997
Suite
$11,785
From
US$6,297
Save 625
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: May 2026 to Nov 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Multiple Deals Available
Inside
-
River View
$3,199
Balcony
$3,699
Suite
$4,999
From
US$3,199
Save 1,200
Per Person
View Trip
8 Day Main & Rhine Christmas Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Basel
Cruise Line: Celebrity Cruises
Ship: Celebrity Compass
Departure: 22 December 2028
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$3,899
Balcony
$5,199
Suite
$7,754
From
US$3,899
Save 2,339
Per Person
View Trip
11 Day Christmas on the Rhine & Main with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Cruise Line: Viking River Cruises
Ships: Viking Eldir, Viking Kvasir (+2 more), Viking Modi, Viking Skirnir
Departures: Nov 2026 to Dec 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Viking $999 Air Deal
Exclusive Savings
Inside
-
River View
$4,699
Balcony
$6,099
Suite
$9,999
From
US$4,699
Save 100
Per Person
View Trip
8 Day Rhine & Main River Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Cruise Line: Celebrity Cruises
Ship: Celebrity Compass
Departure: 11 May 2028
Rivers: Rhine, Main
Visit: Holland, Germany
Exclusive Savings
Inside
-
River View
$4,899
Balcony
$6,552
Suite
$9,841
From
US$4,899
Save 2,939
Per Person
View Trip
10 Day Christmastime from Nuremberg to Basel with Avalon River Cruises
River Cruise

10 Days Nuremberg to Basel
Cruise Line: Avalon River Cruises
Ships: Avalon Illumination, Avalon Tranquility II, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$6,547
Balcony
$7,830
Suite
$11,560
From
US$5,195
Save 750
Per Person
View Trip
12 Day Christmastime from Vienna to Frankfurt with Avalon River Cruises
River Cruise

12 Days Vienna to Frankfurt
Cruise Line: Avalon River Cruises
Ships: Avalon Imagery II, Avalon Vista
Departure: 03 December 2027
Rivers: Danube, Main
Visit: Austria, Germany
Exclusive Savings
Inside
-
River View
$7,744
Balcony
$11,044
Suite
-
From
US$7,744
Save 150
Per Person
View Trip
13 Day Christmastime from Frankfurt to Budapest with Avalon River Cruises
River Cruise

13 Days Frankfurt to Budapest
Cruise Line: Avalon River Cruises
Ship: Avalon Panorama
Departure: 01 December 2027
Rivers: Main, Danube
Visit: Germany, Austria, Hungary
Inside
-
River View
$8,630
Balcony
$12,229
Suite
$15,314
From
US$8,630
Per Person
View Trip
13 Day Christmastime from Budapest to Frankfurt with Avalon River Cruises
River Cruise

13 Days Budapest to Frankfurt
Cruise Line: Avalon River Cruises
Ship: Avalon Passion
Departure: 29 November 2027
Rivers: Danube, Main
Visit: Hungary, Austria, Germany
Inside
-
River View
$8,630
Balcony
$12,229
Suite
-
From
US$8,630
Per Person
View Trip
15 Day Christmastime from Budapest to Frankfurt with Budapest with Avalon River Cruises
New ReleaseRiver Cruise

15 Days Budapest to Frankfurt
Cruise Line: Avalon River Cruises
Ship: Avalon Passion
Departure: 27 November 2027
Rivers: Danube, Main
Visit: Hungary, Austria, Germany
Inside
-
River View
$9,229
Balcony
$12,828
Suite
-
From
US$9,229
Per Person
View Trip
9 Day Christmastime on the Danube with Prague (Eastbound) with Avalon River Cruises
River Cruise

9 Days Prague to Vienna
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Imagery II (+5 more), Avalon Impression, Avalon Passion, Avalon Tranquility II, Avalon Visionary, Avalon Vista
Departures: Dec 2026 to Dec 2027
Rivers: Main, Danube
Visit: Czech Republic, Germany, Austria
Exclusive Savings
Inside
-
River View
$4,214
Balcony
$5,264
Suite
$7,556
From
US$3,636
Save 750
Per Person
View Trip
12 Day Christmastime from Frankfurt to Vienna with Avalon River Cruises
River Cruise

12 Days Frankfurt to Vienna
Cruise Line: Avalon River Cruises
Ships: Avalon Tranquility II, Avalon Vista (+2 more), Avalon Expression, Avalon Imagery II
Departures: Dec 2026 to Dec 2027
Rivers: Main, Danube
Visit: Germany, Austria
Exclusive Savings
Inside
-
River View
$7,519
Balcony
$9,253
Suite
$13,646
From
US$6,111
Save 750
Per Person
View Trip
Results: 1-30 of 143

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Cities

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Routes

River Cruises from Amsterdam to Amsterdam River Cruises from Amsterdam to Budapest River Cruises from Amsterdam to Zurich River Cruises from Amsterdam to Basel River Cruises from Basel to Amsterdam River Cruises from Brussels to Amsterdam River Cruises from Bucharest to Budapest River Cruises from Budapest to Amsterdam River Cruises from Budapest to Munich River Cruises from Budapest to Nuremberg River Cruises from Budapest to Passau River Cruises from Budapest to Bucharest River Cruises from Budapest to Prague River Cruises from Cologne to Cologne River Cruises from Nuremberg to Budapest River Cruises from Paris to Prague River Cruises from Paris to Paris River Cruises from Passau to Passau River Cruises from Passau to Budapest River Cruises from Prague to Bucharest River Cruises from Prague to Paris River Cruises from Prague to Amsterdam River Cruises from Prague to Budapest River Cruises from Zurich to Amsterdam

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