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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 61 unique river cruise itineraries with 94 past traveler reviews from 4 leading river cruise lines. May is the most popular month to join a luxury river cruise along the Main with 389 departures starting between May 2026 and December 2028.
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61 River Cruises (389 River Cruise Departures)
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$8,819
From
US$4,589
Save 520
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$7,799
From
US$4,589
Save 540
Per Person
View Trip
8 Day Rhine & Main River Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Cruise Line: Celebrity Cruises
Ship: Celebrity Compass
Departure: 11 May 2028
Rivers: Rhine, Main
Visit: Holland, Germany
Exclusive Savings
Inside
-
River View
$4,899
Balcony
$6,552
Suite
-
From
US$4,899
Save 2,939
Per Person
View Trip
8 Day Main & Rhine Christmas Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Basel
Cruise Line: Celebrity Cruises
Ships: Celebrity Compass, Celebrity Seeker
Departures: Dec 2027 to Dec 2028
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$3,899
Balcony
$5,199
Suite
$7,754
From
US$3,899
Save 4,259
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Jun 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: Jun 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (12)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby, Scenic Pearl
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$7,631
Balcony
$9,836
Suite
$13,027
From
US$7,631
Save 1,276
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (9)

24 Days Amsterdam to Bucharest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Marlene
Departures: Jun 2026 to May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
Inside
-
River View
$11,999
Balcony
$16,379
Suite
$22,399
From
US$11,999
Save 1,475
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$5,439
Balcony
$7,079
Suite
$13,479
From
US$5,439
Save 1,780
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$5,999
Balcony
$8,459
Suite
$12,599
From
US$5,999
Save 1,750
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: May 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$7,406
Balcony
$9,994
Suite
$12,532
From
US$7,406
Save 1,191
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (5)

24 Days Bucharest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jul 2026 to May 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$13,599
Balcony
$15,699
Suite
-
From
US$13,599
Save 1,755
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Select Fare
Exclusive Savings
Inside
-
River View
$12,398
Balcony
$15,296
Suite
$18,554
From
US$12,398
Save 959
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise
 (1)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Pearl
Departures: Nov 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,711
Balcony
$11,299
Suite
$13,612
From
US$8,711
Save 1,171
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Jewel (+2 more), Scenic Amber, Scenic Opal
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Select Fare
Exclusive Savings
Inside
-
River View
$11,466
Balcony
$14,396
Suite
$18,533
From
US$11,466
Save 989
Per Person
View Trip
29 Day Jewels of Europe with Wonders of Switzerland & Austria with Scenic
River Cruise
 (1)

29 Days Zurich to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jewel
Departures: May 2026 to Sep 2026
Rivers: Danube, Main, Rhine
Visit: Switzerland, Germany, Austria, Hungary, Slovakia, Czech Republic, Holland
Inside
-
River View
$27,550
Balcony
$34,280
Suite
-
From
US$27,550
Per Person
View Trip
19 Day Jewels of Europe with Zagreb & Ljubljana with Scenic
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper
Departures: May 2027 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$10,831
Balcony
$13,419
Suite
$15,732
From
US$10,831
Save 989
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jasper (+5 more), Scenic Jewel, Scenic Opal, Scenic Crystal, Scenic Jade, Scenic Ruby
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,851
Balcony
$11,031
Suite
$14,359
From
US$8,851
Save 1,276
Per Person
View Trip
21 Day Christmas Markets with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jasper
Departures: Nov 2027 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Select Fare
Exclusive Savings
Inside
-
River View
$12,371
Balcony
$14,959
Suite
$17,879
From
US$12,371
Save 1,171
Per Person
View Trip
29 Day Iconic Europe, from Bucharest to Amsterdam with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jade
Departure: 09 April 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Inside
-
River View
$19,310
Balcony
$23,695
Suite
-
From
US$19,310
Per Person
View Trip
15 Day European Gems with Uniworld River Cruises
New ReleaseRiver Cruise

15 Days Amsterdam to Vienna
Cruise Line: Uniworld River Cruises
Ship: S.S. Emilie
Departure: 02 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria
Exclusive Savings
Inside
-
River View
$7,649
Balcony
$9,629
Suite
-
From
US$7,649
Save 850
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Hungary
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,711
Balcony
$11,299
Suite
$13,612
From
US$8,711
Save 884
Per Person
View Trip
29 Day Iconic Europe, from Amsterdam to Bucharest with Turkey with Scenic
River Cruise

29 Days Amsterdam to Istanbul
Cruise Line: Scenic
Ship: Scenic Amber
Departure: 24 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+7 more), Slovakia, Hungary, Croatia, Serbia, Romania, Bulgaria, Turkey
Inside
-
River View
$20,460
Balcony
$24,845
Suite
-
From
US$20,460
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$9,153
Balcony
$11,974
Suite
$14,287
From
US$9,153
Save 959
Per Person
View Trip
19 Day Jewels of Europe with Ljubljana & Zagreb with Scenic
River Cruise

19 Days Amsterdam to Zagreb
Cruise Line: Scenic
Ship: Scenic Jade
Departures: Aug 2026 to Jul 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+4 more), Slovakia, Hungary, Slovenia, Croatia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$10,831
Balcony
$13,419
Suite
$15,732
From
US$10,831
Save 989
Per Person
View Trip
22 Day Windmills, Tulips and Belgian Delight with Jewels of Europe with Scenic
New ReleaseRiver Cruise

22 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jewel
Departures: Apr 2027 to Apr 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Belgium, Germany, Austria, Czech Republic, Slovakia, Hungary
Inside
-
River View
$15,490
Balcony
$18,365
Suite
-
From
US$15,490
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Hungary
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$11,151
Balcony
$13,726
Suite
$16,052
From
US$11,151
Save 884
Per Person
View Trip
18 Day Christmas Wonderland with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Select Fare
Exclusive Savings
Inside
-
River View
$11,203
Balcony
$14,101
Suite
$17,334
From
US$11,203
Save 959
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Select Fare
Exclusive Savings
Inside
-
River View
$9,153
Balcony
$11,974
Suite
$14,894
From
US$9,153
Save 959
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Jewel
Departures: Jun 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, France
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$10,566
Balcony
$12,861
Suite
$15,467
From
US$10,566
Save 1,119
Per Person
View Trip
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