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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 53 unique river cruise itineraries with 180 past traveler reviews from 3 leading river cruise lines. August is the most popular month to join a luxury river cruise along the Main with 335 departures starting between February 2026 and December 2027.
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53 River Cruises (335 River Cruise Departures)
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie
Departures: Dec 2026 to Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
-
Balcony
$5,097
Suite
$7,305
From
US$5,097
Save 292
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie
Departures: Nov 2026 to Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
-
Balcony
$6,489
Suite
$8,073
From
US$6,489
Save 298
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Pearl, Scenic Ruby
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$6,129
Balcony
$9,087
Suite
$13,016
From
US$6,129
Save 13,259
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (9)

24 Days Amsterdam to Bucharest
Cruise Line: Uniworld River Cruises
Ship: River Duchess
Departures: Jun 2026 to Aug 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
Inside
-
River View
$13,084
Balcony
-
Suite
-
From
US$13,084
Save 535
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice
Departures: Jun 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$6,738
Balcony
$8,658
Suite
$12,498
From
US$6,738
Save 373
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice
Departures: May 2026 to Oct 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$7,122
Balcony
$9,138
Suite
$12,978
From
US$7,122
Save 327
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Feb 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Multiple Deals Available
Inside
-
River View
$6,129
Balcony
$7,826
Suite
$12,822
From
US$6,129
Save 12,719
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (5)

24 Days Bucharest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice
Departures: May 2026 to Aug 2026
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$12,700
Balcony
$15,676
Suite
-
From
US$12,700
Save 555
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$11,410
Balcony
$14,369
Suite
$17,861
From
US$11,410
Save 9,089
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise
 (1)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$8,020
Balcony
$10,979
Suite
$15,392
From
US$8,020
Save 11,869
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jewel, Scenic Opal
Departures: Oct 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Multiple Deals Available
Inside
-
River View
$10,697
Balcony
$13,656
Suite
$17,584
From
US$10,697
Save 13,318
Per Person
View Trip
29 Day Jewels of Europe with Wonders of Switzerland & Austria with Scenic
River Cruise
 (1)

29 Days Zurich to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jewel
Departure: 12 August 2026
Rivers: Danube, Main, Rhine
Visit: Switzerland, Germany, Austria, Hungary, Slovakia, Czech Republic, Holland
Fly Free Economy
Exclusive Savings
Inside
-
River View
$19,020
Balcony
$21,978
Suite
-
From
US$19,020
Save 9,160
Per Person
View Trip
19 Day Jewels of Europe with Zagreb & Ljubljana with Scenic
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper
Departures: May 2027 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Multiple Deals Available
Inside
-
River View
$8,563
Balcony
$11,522
Suite
$14,529
From
US$8,563
Save 10,087
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+3 more), Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$8,767
Balcony
$11,725
Suite
$16,362
From
US$8,767
Save 13,292
Per Person
View Trip
21 Day Christmas Markets with Paris & Prague with Scenic
River Cruise

21 Days Paris to Prague
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: France, Holland, Germany, Austria, Hungary, Czech Republic
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$11,861
Balcony
$14,369
Suite
$19,233
From
US$11,861
Save 11,966
Per Person
View Trip
24 Day Jewels of Europe with Eastern Europe Explorer with Scenic
River Cruise

24 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Sep 2026
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$12,196
Balcony
$15,154
Suite
$19,374
From
US$12,196
Save 9,451
Per Person
View Trip
29 Day North Sea to the Black Sea with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Jade
Departures: Oct 2026 to Apr 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$16,957
Balcony
$22,594
Suite
$27,929
From
US$16,957
Save 15,875
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland, France
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$10,445
Balcony
$13,171
Suite
$17,817
From
US$10,445
Save 11,930
Per Person
View Trip
21 Day Jewels of Europe with Prague and London with Scenic
New ReleaseRiver Cruise

21 Days Prague to London
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper, Scenic Jewel
Departures: Aug 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland, England
Exclusive Savings
Inside
-
River View
$19,810
Balcony
$25,727
Suite
$33,293
From
US$19,810
Save 876
Per Person
View Trip
29 Day Jewels of Europe with Wonders of Switzerland & Austria with Scenic
River Cruise

29 Days Amsterdam to Zurich
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel
Departures: Jun 2026 to Jul 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary, Switzerland
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$19,180
Balcony
$22,391
Suite
-
From
US$19,180
Save 9,665
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$8,263
Balcony
$11,076
Suite
$14,665
From
US$8,263
Save 8,985
Per Person
View Trip
27 Day Iconic Europe, from Amsterdam to Bucharest with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Amsterdam to Bucharest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Mar 2027 to May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+6 more), Slovakia, Hungary, Croatia, Serbia, Bulgaria, Romania
Fly Free Economy
Exclusive Savings
Inside
-
River View
$16,871
Balcony
$20,218
Suite
-
From
US$16,871
Save 20,541
Per Person
View Trip
18 Day Christmas & New Year with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland, France
Fly Free Economy
Exclusive Savings
Inside
-
River View
$10,236
Balcony
$13,195
Suite
$18,302
From
US$10,236
Save 9,060
Per Person
View Trip
21 Day Christmas Markets with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$11,376
Balcony
$13,496
Suite
$18,748
From
US$11,376
Save 11,954
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$8,951
Balcony
$11,910
Suite
$16,323
From
US$8,951
Save 11,893
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$8,505
Balcony
$11,076
Suite
$15,877
From
US$8,505
Save 11,714
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$11,022
Balcony
$13,981
Suite
$19,233
From
US$11,022
Save 9,089
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$9,194
Balcony
$12,007
Suite
$15,596
From
US$9,194
Save 9,014
Per Person
View Trip
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