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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 58 unique river cruise itineraries with 92 past traveler reviews from 3 leading river cruise lines. May is the most popular month to join a luxury river cruise along the Main with 395 departures starting between March 2026 and December 2027.
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58 River Cruises (395 River Cruise Departures)
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,416
Balcony
$5,366
Suite
$8,477
From
US$4,416
Save 683
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,416
Balcony
$5,366
Suite
$7,497
From
US$4,416
Save 724
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby, Scenic Pearl
Departures: Mar 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$7,425
Balcony
$9,563
Suite
$12,767
From
US$7,425
Save 1,621
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (9)

24 Days Amsterdam to Bucharest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Marlene
Departures: Jun 2026 to Jun 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
Inside
-
River View
$11,262
Balcony
$13,509
Suite
$19,902
From
US$11,262
Save 1,818
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$5,730
Balcony
$8,514
Suite
$12,116
From
US$5,730
Save 1,190
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$6,738
Balcony
$8,141
Suite
$12,116
From
US$6,738
Save 1,135
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Mar 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Multiple Deals Available
Inside
-
River View
$7,206
Balcony
$9,717
Suite
$12,179
From
US$7,206
Save 1,621
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (5)

24 Days Bucharest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: May 2026 to May 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$12,169
Balcony
$14,589
Suite
-
From
US$12,169
Save 1,880
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Preferred Plus Fare + Free Air
Select Fare
Exclusive Savings
Inside
-
River View
$12,048
Balcony
$14,859
Suite
$18,020
From
US$12,048
Save 1,693
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise
 (1)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Pearl
Departures: Nov 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$8,472
Balcony
$10,983
Suite
$13,226
From
US$8,472
Save 1,487
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Jewel (+2 more), Scenic Amber, Scenic Opal
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Preferred Plus Fare + Free Air
Select Fare
Exclusive Savings
Inside
-
River View
$11,982
Balcony
$14,586
Suite
$18,000
From
US$11,982
Save 1,727
Per Person
View Trip
29 Day Jewels of Europe with Wonders of Switzerland & Austria with Scenic
River Cruise
 (1)

29 Days Zurich to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jewel
Departure: 12 August 2026
Rivers: Danube, Main, Rhine
Visit: Switzerland, Germany, Austria, Hungary, Slovakia, Czech Republic, Holland
Exclusive Savings
Inside
-
River View
$27,357
Balcony
$33,274
Suite
-
From
US$27,357
Save 823
Per Person
View Trip
19 Day Jewels of Europe with Zagreb & Ljubljana with Scenic
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper
Departures: May 2027 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$10,529
Balcony
$13,039
Suite
$15,283
From
US$10,529
Save 1,671
Per Person
View Trip
15 Day Amsterdam to Budapest by Riverboat - Southbound with Tauck
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Tauck
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Inside
-
River View
$8,390
Balcony
$9,040
Suite
$12,690
From
US$8,390
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+4 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$8,608
Balcony
$11,118
Suite
$13,362
From
US$8,608
Save 1,651
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Pearl
Departures: Nov 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$9,656
Balcony
$11,945
Suite
$14,410
From
US$9,656
Save 1,524
Per Person
View Trip
34 Day Jewels of Europe with Majestic Britain & Ireland with Scenic
River Cruise

34 Days Dublin to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Jade (+3 more), Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jul 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Ireland, Northern Ireland, Scotland, England (+6 more), Holland, Germany, Czech Republic, Austria, Slovakia, Hungary
Exclusive Savings
Inside
-
River View
$22,689
Balcony
$25,478
Suite
$27,971
From
US$22,689
Save 912
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Holland, Germany, Austria, Hungary, Czech Republic
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$9,656
Balcony
$12,166
Suite
$14,410
From
US$9,656
Save 1,524
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$8,901
Balcony
$11,637
Suite
$14,470
From
US$8,901
Save 1,583
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Preferred Plus Fare + Free Air
Select Fare
Exclusive Savings
Inside
-
River View
$9,686
Balcony
$12,498
Suite
$15,064
From
US$9,686
Save 1,619
Per Person
View Trip
21 Day Christmas Markets with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
-
Balcony
$13,919
Suite
$17,365
From
US$13,919
Save 1,597
Per Person
View Trip
15 Day Budapest to Amsterdam by Riverboat - Northbound with Tauck
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Inside
-
River View
$8,390
Balcony
$9,040
Suite
$12,690
From
US$8,390
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$10,060
Balcony
$12,821
Suite
$15,653
From
US$10,060
Save 1,619
Per Person
View Trip
21 Day Christmas Markets with Paris & Prague with Scenic
River Cruise

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Crystal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: France, Holland, Germany, Austria, Hungary, Czech Republic
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$12,022
Balcony
$14,307
Suite
$16,776
From
US$12,022
Save 1,597
Per Person
View Trip
29 Day Iconic Europe, from Amsterdam to Bucharest with Turkey with Scenic
River Cruise

29 Days Amsterdam to Istanbul
Cruise Line: Scenic
Ship: Scenic Amber
Departure: 24 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+7 more), Slovakia, Hungary, Croatia, Serbia, Romania, Bulgaria, Turkey
Exclusive Savings
Inside
-
River View
$19,881
Balcony
$24,135
Suite
-
From
US$19,881
Save 579
Per Person
View Trip
22 Day Windmills, Tulips and Belgian Delight with Jewels of Europe with Scenic
New ReleaseRiver Cruise

22 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Ruby
Departures: Mar 2027 to Mar 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, Belgium
Exclusive Savings
Inside
-
River View
$14,527
Balcony
$18,780
Suite
$23,834
From
US$14,527
Save 545
Per Person
View Trip
29 Day Iconic Europe, from Bucharest to Amsterdam with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jade
Departure: 09 April 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Exclusive Savings
Inside
-
River View
$18,766
Balcony
$23,019
Suite
$26,992
From
US$18,766
Save 544
Per Person
View Trip
21 Day Jewels of Europe with Prague and London with Scenic
New ReleaseRiver Cruise

21 Days Prague to London
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel
Departures: Aug 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland, England
Preferred Plus Fare + Free Air
Select Fare
Exclusive Savings
Inside
-
River View
$11,401
Balcony
$14,064
Suite
$17,518
From
US$11,401
Save 1,361
Per Person
View Trip
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