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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 61 unique river cruise itineraries with 92 past traveler reviews from 4 leading river cruise lines. May is the most popular month to join a luxury river cruise along the Main with 408 departures starting between April 2026 and December 2028.
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61 River Cruises (408 River Cruise Departures)
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$8,819
From
US$4,589
Save 510
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$7,799
From
US$4,589
Save 540
Per Person
View Trip
8 Day Rhine & Main River Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Cruise Line: Celebrity Cruises
Ship: Celebrity Compass
Departure: 11 May 2028
Rivers: Rhine, Main
Visit: Holland, Germany
Exclusive Savings
Inside
-
River View
$4,899
Balcony
$6,552
Suite
$9,841
From
US$4,899
Save 2,939
Per Person
View Trip
8 Day Main & Rhine Christmas Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Basel
Cruise Line: Celebrity Cruises
Ship: Celebrity Compass
Departure: 22 December 2028
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$3,899
Balcony
$5,199
Suite
$7,754
From
US$3,899
Save 2,339
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby, Scenic Pearl
Departures: Apr 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$7,631
Balcony
$9,836
Suite
$13,139
From
US$7,631
Save 1,319
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (9)

24 Days Amsterdam to Bucharest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Marlene
Departures: Jun 2026 to May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
Inside
-
River View
$12,914
Balcony
$15,569
Suite
$24,119
From
US$12,914
Save 1,435
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$4,759
Balcony
$7,079
Suite
$13,319
From
US$4,759
Save 1,190
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$5,999
Balcony
$8,599
Suite
$12,959
From
US$5,999
Save 1,500
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Apr 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Multiple Deals Available
Inside
-
River View
$7,406
Balcony
$9,994
Suite
$12,532
From
US$7,406
Save 1,286
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (5)

24 Days Bucharest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: May 2026 to May 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$13,094
Balcony
$15,794
Suite
-
From
US$13,094
Save 1,455
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Multiple Deals Available
Inside
-
River View
$12,398
Balcony
$15,296
Suite
$18,554
From
US$12,398
Save 959
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise
 (1)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Pearl
Departures: Nov 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,711
Balcony
$11,299
Suite
$13,612
From
US$8,711
Save 1,171
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Jewel (+2 more), Scenic Opal, Scenic Amber
Departures: May 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Select Fare
Exclusive Savings
Inside
-
River View
$11,466
Balcony
$14,211
Suite
$18,533
From
US$11,466
Save 1,239
Per Person
View Trip
29 Day Jewels of Europe with Wonders of Switzerland & Austria with Scenic
River Cruise
 (1)

29 Days Zurich to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jewel
Departure: 12 August 2026
Rivers: Danube, Main, Rhine
Visit: Switzerland, Germany, Austria, Hungary, Slovakia, Czech Republic, Holland
Inside
-
River View
-
Balcony
$34,280
Suite
-
From
US$34,280
Per Person
View Trip
19 Day Jewels of Europe with Zagreb & Ljubljana with Scenic
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper
Departures: May 2027 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$10,831
Balcony
$13,419
Suite
$15,732
From
US$10,831
Save 989
Per Person
View Trip
24 Day Jewels of Europe with Eastern Europe Explorer with Scenic
River Cruise

24 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Jade (+3 more), Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: May 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$14,226
Balcony
$16,814
Suite
$19,127
From
US$14,226
Save 989
Per Person
View Trip
21 Day Christmas Markets with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Multiple Deals Available
Inside
-
River View
$12,371
Balcony
$14,326
Suite
$17,879
From
US$12,371
Save 1,171
Per Person
View Trip
22 Day Windmills, Tulips and Belgian Delight with Jewels of Europe with Scenic
New ReleaseRiver Cruise

22 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Ruby
Departures: Mar 2027 to Mar 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, Belgium
Inside
-
River View
$14,940
Balcony
$19,325
Suite
$24,535
From
US$14,940
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Hungary
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,711
Balcony
$11,299
Suite
$13,612
From
US$8,711
Save 884
Per Person
View Trip
34 Day Jewels of Europe with Majestic Britain & Ireland with Scenic
River Cruise

34 Days Dublin to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Jade (+3 more), Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jul 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Ireland, Northern Ireland, Scotland, England (+6 more), Holland, Germany, Czech Republic, Austria, Slovakia, Hungary
Preferred Plus Fare + Reduced Air Offer
Inside
-
River View
$23,360
Balcony
$26,235
Suite
$28,805
From
US$23,360
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$9,963
Balcony
$12,861
Suite
$15,507
From
US$9,963
Save 959
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Jewel
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, France
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$10,566
Balcony
$12,861
Suite
$15,467
From
US$10,566
Save 1,119
Per Person
View Trip
27 Day Iconic Europe, from Bucharest to Amsterdam with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Inside
-
River View
$17,195
Balcony
$21,580
Suite
-
From
US$17,195
Per Person
View Trip
29 Day Iconic Europe, from Amsterdam to Bucharest with Turkey with Scenic
River Cruise

29 Days Amsterdam to Istanbul
Cruise Line: Scenic
Ship: Scenic Amber
Departure: 24 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+7 more), Slovakia, Hungary, Croatia, Serbia, Romania, Bulgaria, Turkey
Inside
-
River View
$20,460
Balcony
$24,845
Suite
-
From
US$20,460
Per Person
View Trip
25 Day Grand European Cruise - Eastbound with Tauck
River Cruise

25 Days Amsterdam to Bucharest
Cruise Line: Tauck
Departures: Jul 2026 to Aug 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia (+5 more), Hungary, Croatia, Serbia, Bulgaria, Romania
Inside
-
River View
$15,290
Balcony
$16,340
Suite
$21,990
From
US$15,290
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland, France
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$11,151
Balcony
$13,516
Suite
$16,659
From
US$11,151
Save 1,171
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$9,153
Balcony
$11,974
Suite
$14,894
From
US$9,153
Save 959
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+4 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: May 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,851
Balcony
$11,439
Suite
$13,752
From
US$8,851
Save 1,119
Per Person
View Trip
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