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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 53 unique river cruise itineraries with 64 past traveler reviews from 3 leading river cruise lines. August is the most popular month to join a luxury river cruise along the Main with 337 departures starting between February 2026 and December 2027.
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53 River Cruises (337 River Cruise Departures)
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie
Departures: Dec 2026 to Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
-
Balcony
$6,249
Suite
$7,305
From
US$6,249
Save 300
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie
Departures: Nov 2026 to Dec 2026
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$5,337
Balcony
$5,577
Suite
$8,553
From
US$5,337
Save 298
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby, Scenic Pearl
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$8,796
Suite
$12,725
From
US$6,080
Save 13,972
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (9)

24 Days Amsterdam to Bucharest
Cruise Line: Uniworld River Cruises
Ship: River Duchess
Departures: Jun 2026 to Aug 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
Inside
-
River View
$13,084
Balcony
-
Suite
-
From
US$13,084
Save 535
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice
Departures: Jun 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$5,730
Balcony
$8,514
Suite
$12,978
From
US$5,730
Save 381
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice
Departures: May 2026 to Oct 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$7,122
Balcony
$10,338
Suite
$15,330
From
US$7,122
Save 327
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Feb 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$8,796
Suite
$12,725
From
US$6,080
Save 13,689
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (5)

24 Days Bucharest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice
Departures: Aug 2026 to Aug 2026
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$12,700
Balcony
$15,676
Suite
-
From
US$12,700
Save 515
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,440
Balcony
$13,399
Suite
$17,778
From
US$10,440
Save 10,310
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise
 (1)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,535
Balcony
$10,227
Suite
$14,422
From
US$7,535
Save 12,839
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Opal
Departures: Apr 2027 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,988
Balcony
$13,947
Suite
$17,875
From
US$10,988
Save 10,574
Per Person
View Trip
29 Day Jewels of Europe with Wonders of Switzerland & Austria with Scenic
River Cruise
 (1)

29 Days Zurich to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jewel
Departure: 12 August 2026
Rivers: Danube, Main, Rhine
Visit: Switzerland, Germany, Austria, Hungary, Slovakia, Czech Republic, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$18,050
Balcony
$21,008
Suite
-
From
US$18,050
Save 10,130
Per Person
View Trip
19 Day Jewels of Europe with Zagreb & Ljubljana with Scenic
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper
Departures: May 2027 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,854
Balcony
$11,813
Suite
$14,820
From
US$8,854
Save 10,105
Per Person
View Trip
25 Day Grand European Cruise - Eastbound with Tauck
River Cruise

25 Days Amsterdam to Bucharest
Cruise Line: Tauck
Departures: Jul 2026 to Aug 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia (+5 more), Hungary, Croatia, Serbia, Bulgaria, Romania
Inside
-
River View
$15,290
Balcony
$16,340
Suite
$21,990
From
US$15,290
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Jewel
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,072
Balcony
$11,449
Suite
$15,150
From
US$9,072
Save 12,076
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,466
Balcony
$11,012
Suite
$15,353
From
US$8,466
Save 12,863
Per Person
View Trip
15 Day Amsterdam to Budapest by Riverboat - Southbound with Tauck
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Tauck
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Inside
-
River View
$8,390
Balcony
$9,040
Suite
$12,690
From
US$8,390
Per Person
View Trip
23 Day Iconic Europe, from Amsterdam to Bucharest with Scenic
River Cruise

23 Days Amsterdam to Bucharest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Mar 2027 to May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+6 more), Slovakia, Hungary, Croatia, Serbia, Bulgaria, Romania
Early Booking Savings
Exclusive Savings
Inside
-
River View
$14,866
Balcony
$18,213
Suite
-
From
US$14,866
Save 21,267
Per Person
View Trip
29 Day North Sea to the Black Sea with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Jade
Departures: Oct 2026 to Apr 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,987
Balcony
$21,624
Suite
$26,474
From
US$15,987
Save 16,845
Per Person
View Trip
21 Day Christmas Markets with Paris & Prague with Scenic
River Cruise

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: France, Holland, Germany, Austria, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,440
Balcony
$13,399
Suite
$17,778
From
US$10,440
Save 10,059
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,537
Balcony
$13,496
Suite
$17,778
From
US$10,537
Save 10,298
Per Person
View Trip
19 Day Jewels of Europe with Ljubljana & Zagreb with Scenic
River Cruise

19 Days Amsterdam to Zagreb
Cruise Line: Scenic
Ship: Scenic Jade
Departures: Aug 2026 to Jul 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+4 more), Slovakia, Hungary, Slovenia, Croatia
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,854
Balcony
$11,813
Suite
$14,820
From
US$8,854
Save 13,502
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,293
Balcony
$10,106
Suite
$14,422
From
US$7,293
Save 10,212
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,224
Balcony
$11,037
Suite
$15,353
From
US$8,224
Save 10,248
Per Person
View Trip
25 Day Grand European Cruise - Westbound with Tauck
River Cruise

25 Days Bucharest to Amsterdam
Cruise Line: Tauck
Departures: Aug 2026 to Jul 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+5 more), Hungary, Slovakia, Austria, Germany, Holland
Inside
-
River View
$14,690
Balcony
$15,740
Suite
$21,390
From
US$14,690
Per Person
View Trip
27 Day Iconic Europe, from Amsterdam to Bucharest with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Amsterdam to Bucharest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Mar 2027 to May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+6 more), Slovakia, Hungary, Croatia, Serbia, Bulgaria, Romania
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,901
Balcony
$19,248
Suite
-
From
US$15,901
Save 21,511
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,535
Balcony
$10,494
Suite
$14,422
From
US$7,535
Save 10,212
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ship: Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,281
Balcony
$12,240
Suite
$16,847
From
US$9,281
Save 10,030
Per Person
View Trip
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