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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 55 unique river cruise itineraries with 92 past traveler reviews from 3 leading river cruise lines. May is the most popular month to join a luxury river cruise along the Main with 362 departures starting between April 2026 and December 2027.
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55 River Cruises (362 River Cruise Departures)
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,416
Balcony
$5,366
Suite
$8,477
From
US$4,416
Save 683
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,416
Balcony
$5,366
Suite
$7,497
From
US$4,416
Save 704
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby, Scenic Pearl
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$8,796
Suite
$12,725
From
US$6,080
Save 13,920
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (9)

24 Days Amsterdam to Bucharest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Marlene
Departures: Jun 2026 to Jun 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
Inside
-
River View
$11,262
Balcony
$13,509
Suite
$19,902
From
US$11,262
Save 1,818
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$5,730
Balcony
$8,514
Suite
$12,116
From
US$5,730
Save 1,190
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: May 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$6,738
Balcony
$8,141
Suite
$12,116
From
US$6,738
Save 1,135
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Apr 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$9,039
Suite
$12,046
From
US$6,080
Save 13,843
Per Person
View Trip
24 Day Ultimate European Journey with Uniworld River Cruises
River Cruise
 (5)

24 Days Bucharest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: May 2026 to May 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$12,169
Balcony
$14,589
Suite
-
From
US$12,169
Save 1,880
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,440
Balcony
$13,399
Suite
$16,406
From
US$10,440
Save 10,310
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise
 (1)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Pearl
Departures: Nov 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,535
Balcony
$10,227
Suite
$13,986
From
US$7,535
Save 12,839
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Opal, Scenic Amber
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,595
Balcony
$13,554
Suite
$17,875
From
US$10,595
Save 13,715
Per Person
View Trip
29 Day Jewels of Europe with Wonders of Switzerland & Austria with Scenic
River Cruise
 (1)

29 Days Zurich to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jewel
Departure: 12 August 2026
Rivers: Danube, Main, Rhine
Visit: Switzerland, Germany, Austria, Hungary, Slovakia, Czech Republic, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$18,050
Balcony
$21,008
Suite
-
From
US$18,050
Save 10,130
Per Person
View Trip
19 Day Jewels of Europe with Zagreb & Ljubljana with Scenic
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper
Departures: May 2027 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,854
Balcony
$11,813
Suite
$14,820
From
US$8,854
Save 10,105
Per Person
View Trip
18 Day Christmas & New Year with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,751
Balcony
$12,710
Suite
$15,926
From
US$9,751
Save 10,274
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+4 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,011
Balcony
$9,970
Suite
$13,898
From
US$7,011
Save 11,014
Per Person
View Trip
29 Day North Sea to the Black Sea with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Jade
Departures: Oct 2026 to Apr 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,987
Balcony
$21,624
Suite
$26,474
From
US$15,987
Save 16,845
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,535
Balcony
$10,494
Suite
$13,501
From
US$7,535
Save 10,212
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Opal (+3 more), Scenic Amber, Scenic Crystal, Scenic Jewel
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,505
Balcony
$11,464
Suite
$15,392
From
US$8,505
Save 13,982
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jasper (+5 more), Scenic Jewel, Scenic Opal, Scenic Crystal, Scenic Jade, Scenic Ruby
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,011
Balcony
$9,955
Suite
$13,884
From
US$7,011
Save 13,640
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,224
Balcony
$11,037
Suite
$14,141
From
US$8,224
Save 10,248
Per Person
View Trip
18 Day Christmas Wonderland with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,281
Balcony
$12,240
Suite
$15,247
From
US$9,281
Save 10,274
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,537
Balcony
$13,496
Suite
$16,857
From
US$10,537
Save 10,298
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,475
Balcony
$12,240
Suite
$15,441
From
US$9,475
Save 12,900
Per Person
View Trip
18 Day Jewels of Europe with London with Scenic
New ReleaseRiver Cruise

18 Days Budapest to London
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel, Scenic Ruby
Departures: Aug 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, England
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,305
Balcony
$12,264
Suite
$15,877
From
US$9,305
Save 10,643
Per Person
View Trip
21 Day Christmas Markets with Paris & Prague with Scenic
River Cruise

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Crystal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: France, Holland, Germany, Austria, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,406
Balcony
$13,365
Suite
$16,372
From
US$10,406
Save 12,936
Per Person
View Trip
23 Day Black Sea to the North Sea with Scenic
River Cruise

23 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Amber, Scenic Jade
Departures: Oct 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$12,829
Balcony
$17,776
Suite
$22,626
From
US$12,829
Save 16,272
Per Person
View Trip
27 Day Iconic Europe, from Bucharest to Amsterdam with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$14,543
Balcony
$19,054
Suite
$25,601
From
US$14,543
Save 16,773
Per Person
View Trip
27 Day Iconic Europe, from Amsterdam to Bucharest with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Amsterdam to Bucharest
Cruise Line: Scenic
Ship: Scenic Amber
Departure: 24 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+6 more), Slovakia, Hungary, Croatia, Serbia, Bulgaria, Romania
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,901
Balcony
$20,412
Suite
-
From
US$15,901
Save 17,958
Per Person
View Trip
Results: 1-30 of 55

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