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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 61 unique river cruise itineraries with 92 past traveler reviews from 5 leading river cruise lines. May is the most popular month to join a luxury river cruise along the Main with 394 departures starting between May 2026 and December 2028.
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61 River Cruises (394 River Cruise Departures)
8 Day Main & Rhine Christmas Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Basel
Cruise Line: Celebrity Cruises
Ship: Celebrity Compass
Departure: 22 December 2028
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Exclusive Savings
Inside
-
River View
$3,899
Balcony
$5,199
Suite
$7,754
From
US$3,899
Save 2,339
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Hungary
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,711
Balcony
$11,299
Suite
$13,612
From
US$8,711
Save 884
Per Person
View Trip
34 Day Jewels of Europe with Majestic Britain & Ireland with Scenic
River Cruise

34 Days Dublin to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Jade (+3 more), Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jul 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Ireland, Northern Ireland, Scotland, England (+6 more), Holland, Germany, Czech Republic, Austria, Slovakia, Hungary
Preferred Plus Fare + Reduced Air Offer
Inside
-
River View
$23,360
Balcony
$26,235
Suite
$28,805
From
US$23,360
Per Person
View Trip
18 Day Christmas & New Year with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland, France
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$11,188
Balcony
$14,086
Suite
$16,727
From
US$11,188
Save 959
Per Person
View Trip
23 Day Iconic Europe, from Bucharest to Amsterdam with Scenic
River Cruise

23 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Inside
-
River View
$15,940
Balcony
$20,325
Suite
$25,535
From
US$15,940
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jasper, Scenic Pearl
Departures: Nov 2027 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Preferred Plus Fare + Free Air
Select Fare
Exclusive Savings
Inside
-
River View
$9,931
Balcony
$12,519
Suite
$14,832
From
US$9,931
Save 1,171
Per Person
View Trip
24 Day Jewels of Europe with Eastern Europe Explorer with Scenic
River Cruise

24 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Jade (+3 more), Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: May 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$14,226
Balcony
$16,814
Suite
$19,127
From
US$14,226
Save 989
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
21 Day Christmas Markets with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jasper
Departures: Nov 2027 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$12,371
Balcony
$14,959
Suite
$17,879
From
US$12,371
Save 1,171
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+4 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: May 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$7,591
Balcony
$10,031
Suite
$13,752
From
US$7,591
Save 3,693
Per Person
View Trip
12 Day Paris, Prague & Germany's Hidden Gems with Uniworld River Cruises
New ReleaseRiver Cruise

12 Days Paris to Prague
Cruise Line: Uniworld River Cruises
Ship: S.S. Audrey
Departures: May 2027 to Jul 2027
Rivers: Moselle, Rhine, Main
Visit: France, Luxembourg, Germany, Czech Republic
Exclusive Savings
Inside
-
River View
$5,489
Balcony
$6,434
Suite
$9,179
From
US$5,489
Save 675
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Hungary
Multiple Deals Available
Inside
-
River View
$11,151
Balcony
$13,531
Suite
$16,052
From
US$11,151
Save 884
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Jewel (+3 more), Scenic Opal, Scenic Amber, Scenic Crystal
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Select Fare
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
River View
$8,716
Balcony
$11,156
Suite
$15,579
From
US$8,716
Save 2,729
Per Person
View Trip
15 Day Amsterdam to Budapest by Riverboat - Southbound with Tauck
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Tauck
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Inside
-
River View
$8,390
Balcony
$9,040
Suite
$12,690
From
US$8,390
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Frankfurt to Nuremberg
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Nov 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$8,819
From
US$4,589
Save 510
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Jun 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
29 Day Jewels of Europe & Romantic Rhine & Moselle with Scenic
New ReleaseRiver Cruise

29 Days Zurich to Budapest
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Opal
Departures: May 2027 to Oct 2027
Visit: Switzerland, France, Holland, Belgium (+5 more), Germany, Austria, Czech Republic, Slovakia, Hungary
Inside
-
River View
$20,740
Balcony
$26,490
Suite
$33,330
From
US$20,740
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$9,963
Balcony
$12,861
Suite
$15,507
From
US$9,963
Save 959
Per Person
View Trip
15 Day Budapest to Amsterdam by Riverboat - Northbound with Tauck
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Inside
-
River View
$8,390
Balcony
$9,040
Suite
$12,690
From
US$8,390
Per Person
View Trip
25 Day Grand European Cruise - Westbound with Tauck
River Cruise

25 Days Bucharest to Amsterdam
Cruise Line: Tauck
Departures: Aug 2026 to Jul 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+5 more), Hungary, Slovakia, Austria, Germany, Holland
Inside
-
River View
$14,690
Balcony
$15,740
Suite
$21,390
From
US$14,690
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+5 more), Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Crystal, Scenic Ruby
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Multiple Deals Available
Inside
-
River View
$7,551
Balcony
$9,991
Suite
$14,359
From
US$7,551
Save 2,769
Per Person
View Trip
19 Day Jewels of Europe with Ljubljana & Zagreb with Scenic
River Cruise

19 Days Amsterdam to Zagreb
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Jade
Departures: May 2026 to Jul 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+4 more), Slovakia, Hungary, Slovenia, Croatia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$10,831
Balcony
$13,419
Suite
$15,732
From
US$10,831
Save 989
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$7,799
From
US$4,589
Save 540
Per Person
View Trip
18 Day Jewels of Europe with London with Scenic
New ReleaseRiver Cruise

18 Days Budapest to London
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel, Scenic Ruby
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, England
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$11,946
Balcony
$14,534
Suite
$17,042
From
US$11,946
Save 989
Per Person
View Trip
21 Day Christmas & New Year with Paris & Prague with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Multiple Deals Available
Inside
-
River View
$11,998
Balcony
$14,896
Suite
$17,947
From
US$11,998
Save 959
Per Person
View Trip
22 Day Windmills, Tulips and Belgian Delight with Jewels of Europe with Scenic
New ReleaseRiver Cruise

22 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Ruby
Departures: Mar 2027 to Mar 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, Belgium
Inside
-
River View
$14,940
Balcony
$19,325
Suite
$24,535
From
US$14,940
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Select Fare
Exclusive Savings
Inside
-
River View
$10,348
Balcony
$13,194
Suite
$16,114
From
US$10,348
Save 959
Per Person
View Trip
8 Day Main & Rhine New Year's Cruise with Celebrity Cruises
New ReleaseRiver Cruise

8 Days Nuremberg to Amsterdam
Cruise Line: Celebrity Cruises
Ship: Celebrity Seeker
Departure: 29 December 2028
Visit: Germany, Holland
Exclusive Savings
Inside
-
River View
$3,899
Balcony
$5,299
Suite
$7,399
From
US$3,899
Save 2,339
Per Person
View Trip
12 Day Paris, Prague & Germany's Hidden Gems with Uniworld River Cruises
New ReleaseRiver Cruise

12 Days Prague to Paris
Cruise Line: Uniworld River Cruises
Ship: S.S. Audrey
Departures: May 2027 to Jul 2027
Rivers: Main, Rhine, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Exclusive Savings
Inside
-
River View
$5,489
Balcony
$6,434
Suite
$9,179
From
US$5,489
Save 630
Per Person
View Trip
29 Day Jewels of Europe & Romantic Rhine & Moselle with Scenic
New ReleaseRiver Cruise

29 Days Budapest to Zurich
Cruise Line: Scenic
Ships: Scenic Ruby, Scenic Pearl
Departure: 02 June 2027
Visit: Hungary, Slovakia, Austria, Czech Republic (+5 more), Germany, Holland, Belgium, France, Switzerland
Select Fare
Exclusive Savings
Inside
-
River View
$18,817
Balcony
$24,280
Suite
-
From
US$18,817
Save 1,923
Per Person
View Trip
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