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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 55 unique river cruise itineraries with 92 past traveler reviews from 4 leading river cruise lines. May is the most popular month to join a luxury river cruise along the Main with 362 departures starting between April 2026 and December 2027.
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55 River Cruises (362 River Cruise Departures)
27 Day Iconic Europe, from Amsterdam to Bucharest with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Amsterdam to Bucharest
Cruise Line: Scenic
Ship: Scenic Amber
Departure: 24 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+6 more), Slovakia, Hungary, Croatia, Serbia, Bulgaria, Romania
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,901
Balcony
$20,412
Suite
-
From
US$15,901
Save 17,958
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Holland, Germany, Austria, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,981
Balcony
$10,940
Suite
$13,947
From
US$7,981
Save 12,875
Per Person
View Trip
15 Day European Gems with Uniworld River Cruises
New ReleaseRiver Cruise

15 Days Amsterdam to Vienna
Cruise Line: Uniworld River Cruises
Ship: S.S. Emilie
Departure: 02 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria
Exclusive Savings
Inside
-
River View
$7,105
Balcony
$9,178
Suite
$12,029
From
US$7,105
Save 1,094
Per Person
View Trip
18 Day Christmas Markets with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Pearl
Departures: Nov 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,466
Balcony
$11,012
Suite
$14,917
From
US$8,466
Save 13,125
Per Person
View Trip
21 Day Christmas Markets with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,891
Balcony
$12,526
Suite
$17,778
From
US$10,891
Save 13,200
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+4 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,011
Balcony
$9,970
Suite
$13,898
From
US$7,011
Save 11,014
Per Person
View Trip
27 Day Iconic Europe, from Bucharest to Amsterdam with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$14,543
Balcony
$19,054
Suite
$26,765
From
US$14,543
Save 16,773
Per Person
View Trip
21 Day Jewels of Europe with Prague and London with Scenic
New ReleaseRiver Cruise

21 Days Prague to London
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel
Departures: Aug 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland, England
Exclusive Savings
Inside
-
River View
$16,082
Balcony
$21,999
Suite
$33,293
From
US$16,082
Save 608
Per Person
View Trip
18 Day Christmas Wonderland with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,281
Balcony
$12,240
Suite
$15,247
From
US$9,281
Save 10,274
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,475
Balcony
$12,240
Suite
$15,441
From
US$9,475
Save 12,900
Per Person
View Trip
18 Day Jewels of Europe with London with Scenic
New ReleaseRiver Cruise

18 Days Budapest to London
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel, Scenic Ruby
Departures: Aug 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, England
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,305
Balcony
$12,264
Suite
$15,877
From
US$9,305
Save 10,643
Per Person
View Trip
18 Day Christmas Markets with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,960
Balcony
$12,201
Suite
$16,847
From
US$9,960
Save 13,171
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Jasper
Departures: Dec 2026 to Dec 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,293
Balcony
$10,106
Suite
$13,210
From
US$7,293
Save 10,212
Per Person
View Trip
29 Day North Sea to the Black Sea with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Jade
Departures: Oct 2026 to Apr 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,987
Balcony
$21,624
Suite
-
From
US$15,987
Save 16,845
Per Person
View Trip
15 Day Christmas Markets with Scenic
River Cruise

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Nov 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,050
Balcony
$10,009
Suite
$13,016
From
US$7,050
Save 12,839
Per Person
View Trip
29 Day Iconic Europe, from Amsterdam to Bucharest with Turkey with Scenic
River Cruise

29 Days Amsterdam to Istanbul
Cruise Line: Scenic
Ship: Scenic Amber
Departure: 24 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+7 more), Slovakia, Hungary, Croatia, Serbia, Romania, Bulgaria, Turkey
Early Booking Savings
Exclusive Savings
Inside
-
River View
$18,024
Balcony
$22,534
Suite
-
From
US$18,024
Save 17,811
Per Person
View Trip
25 Day Grand European Cruise - Westbound with Tauck
River Cruise

25 Days Bucharest to Amsterdam
Cruise Line: Tauck
Departures: Aug 2026 to Jul 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+5 more), Hungary, Slovakia, Austria, Germany, Holland
Inside
-
River View
$14,690
Balcony
$15,740
Suite
$21,390
From
US$14,690
Per Person
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,466
Balcony
$11,425
Suite
$14,432
From
US$8,466
Save 10,237
Per Person
View Trip
21 Day Christmas Markets with Paris & Prague with Scenic
River Cruise

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Crystal
Departures: Nov 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: France, Holland, Germany, Austria, Hungary, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,406
Balcony
$13,365
Suite
$16,372
From
US$10,406
Save 12,936
Per Person
View Trip
23 Day Black Sea to the North Sea with Scenic
River Cruise

23 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Opal, Scenic Amber, Scenic Jade
Departures: Oct 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$12,829
Balcony
$17,776
Suite
$24,275
From
US$12,829
Save 16,272
Per Person
View Trip
15 Day Christmas & New Year with Scenic
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Opal
Departures: Dec 2026 to Dec 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,535
Balcony
$10,494
Suite
$13,501
From
US$7,535
Save 10,212
Per Person
View Trip
12 Day Paris, Prague & Germany's Hidden Gems with Uniworld River Cruises
New ReleaseRiver Cruise

12 Days Prague to Paris
Cruise Line: Uniworld River Cruises
Ship: S.S. Audrey
Departures: May 2027 to Jul 2027
Rivers: Main, Rhine, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Exclusive Savings
Inside
-
River View
$5,625
Balcony
$6,662
Suite
$9,600
From
US$5,625
Save 942
Per Person
View Trip
12 Day Paris, Prague & Germany's Hidden Gems with Uniworld River Cruises
New ReleaseRiver Cruise

12 Days Paris to Prague
Cruise Line: Uniworld River Cruises
Ship: S.S. Audrey
Departures: May 2027 to Jul 2027
Rivers: Moselle, Rhine, Main
Visit: France, Luxembourg, Germany, Czech Republic
Exclusive Savings
Inside
-
River View
$5,625
Balcony
$6,662
Suite
$9,600
From
US$5,625
Save 942
Per Person
View Trip
29 Day Jewels of Europe & Romantic Rhine & Moselle with Scenic
New ReleaseRiver Cruise

29 Days Budapest to Zurich
Cruise Line: Scenic
Ship: Scenic Jasper
Departure: 29 September 2026
Visit: Hungary, Slovakia, Austria, Czech Republic (+5 more), Germany, Holland, Belgium, France, Switzerland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,070
Balcony
$20,987
Suite
-
From
US$15,070
Save 17,910
Per Person
View Trip
29 Day Jewels of Europe & Romantic Rhine & Moselle with Scenic
New ReleaseRiver Cruise

29 Days Zurich to Budapest
Cruise Line: Scenic
Ships: Scenic Jasper, Scenic Ruby
Departures: Oct 2026 to Oct 2026
Visit: Switzerland, France, Holland, Belgium (+5 more), Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$19,435
Suite
-
From
US$19,435
Save 23,575
Per Person
View Trip
Results: 31-55 of 55

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