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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main. Choose from 65 unique river cruise itineraries with 98 past traveler reviews from 5 leading river cruise lines. May is the most popular month to join a luxury river cruise along the Main with 389 departures starting between June 2026 and December 2028.
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34 Days
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65 River Cruises (389 River Cruise Departures)
27 Day Iconic Europe, from Bucharest to Amsterdam with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Inside
-
River View
$17,195
Balcony
$21,580
Suite
-
From
US$17,195
Per Person
View Trip
8 Day Classic Christmas Markets with Uniworld River Cruises
River Cruise

8 Days Nuremberg to Frankfurt
Cruise Line: Uniworld River Cruises
Ships: S.S. Elisabeth, S.S. Emilie, S.S. Audrey
Departures: Dec 2026 to Dec 2027
Rivers: Main
Visit: Germany
Early Booking Savings
Exclusive Savings
Inside
-
River View
$4,589
Balcony
$5,579
Suite
$7,799
From
US$4,589
Save 540
Per Person
View Trip
29 Day Jewels of Europe & Romantic Rhine & Moselle with Scenic
New ReleaseRiver Cruise

29 Days Budapest to Zurich
Cruise Line: Scenic
Ships: Scenic Ruby, Scenic Pearl
Departure: 02 June 2027
Visit: Hungary, Slovakia, Austria, Czech Republic (+5 more), Germany, Holland, Belgium, France, Switzerland
Inside
-
River View
$20,740
Balcony
$26,490
Suite
-
From
US$20,740
Per Person
View Trip
15 Day Budapest to Amsterdam by Riverboat - Northbound with Tauck
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Tauck
Departures: Jun 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Inside
-
River View
$8,390
Balcony
$9,040
Suite
$12,690
From
US$8,390
Per Person
View Trip
29 Day Iconic Europe, from Amsterdam to Bucharest with Turkey with Scenic
River Cruise

29 Days Amsterdam to Istanbul
Cruise Line: Scenic
Ship: Scenic Amber
Departure: 24 May 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic (+7 more), Slovakia, Hungary, Croatia, Serbia, Romania, Bulgaria, Turkey
Inside
-
River View
$20,460
Balcony
$24,845
Suite
-
From
US$20,460
Per Person
View Trip
Results: 61-65 of 65

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Europe River Cruises

Bordeaux River Cruises Danube River Cruises Douro River Cruises Elbe River Cruises Europe River Cruises France River Cruises Holland & Belgium River Cruises Italy River Cruises Main River Cruises Mississippi River Cruises Moselle River Cruises Nile River Cruises Rhine River Cruises Rhône River Cruises Saône River Cruises Seine & Normandy River Cruises

Luxury River Cruises By Region

Bordeaux Danube Egypt Europe France Holland & Belgium Italy Moselle River Portugal Rhine River Rhône River Saône River Seine River

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Christmas Markets Festive River Cruises Food & Wine River Cruises Luxury River Cruises Winter River Cruises

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