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River Cruises from Amsterdam to Prague

Are you looking for a river cruise from Amsterdam to Prague? June is the most popular month to river cruise between Amsterdam and Prague and there are 84 departures available from four of the world's leading river cruise lines.
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7 River Cruises (84 River Cruise Departures)
18 Day European Gems with Travelmarvel
River Cruise
 (7)

18 Days Amsterdam to Prague
Operated By: Travelmarvel
Ships: Capella, Polaris (+3 more), Vega, Polaris, Vega
Departures: May 2024 to Dec 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Hungary (+1 more), Czech Republic
Exclusive DealFlights Included and Save
Save 3,058
From 5,406
View Trip
18 Day Magnificent Europe with Prague with APT
River Cruise
 (10)

18 Days Amsterdam to Prague
Operated By: APT
Ships: MS AmaReina, MS AmaStella (+3 more), MS AmaVenita, APT Ostara, APT Solara
Departures: May 2024 to Dec 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Last Minute DealsFlights Included
Save 1,805
From 10,010
View Trip
18 Day Splendours of Europe with Prague with Emerald Cruises
River Cruise
 (1)

18 Days Amsterdam to Prague
Operated By: Emerald Cruises
Ships: Emerald Dawn, Emerald Destiny (+4 more), Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: Apr 2024 to Aug 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Exclusive Deal
INSIDE
-
RIVER VIEW
$6,934
BALCONY
$8,636
SUITE
$11,885
Save 3,574
From 6,934
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Operated By: Scenic
Ships: Scenic Crystal, Scenic Crystal (+6 more), Scenic Jade, Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Jewel, Scenic Ruby
Departures: May 2024 to Oct 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Hungary (+2 more), Slovakia, Czech Republic
Exclusive Deal
INSIDE
-
RIVER VIEW
$8,240
BALCONY
$11,567
SUITE
$15,616
Save 2,656
From 8,240
View Trip
18 Day Prague & Christmas Markets of Europe with Emerald Cruises
River Cruise

18 Days Amsterdam to Prague
Operated By: Emerald Cruises
Ship: Emerald Sun
Departure: 06 December 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Exclusive Deal
INSIDE
-
RIVER VIEW
$7,173
BALCONY
$9,103
SUITE
$11,736
Save 2,572
From 7,173
View Trip
24 Day Eastern Europe and European Gems River Cruise with Travelmarvel
River Cruise

24 Days Amsterdam to Prague
Operated By: Travelmarvel
Ships: Polaris, Vega
Departures: May 2025 to Jun 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Hungary (+3 more), Slovakia, Poland, Czech Republic
Flights Included and Save
Save 619
From 13,476
View Trip
18 Day Christmas & New Year with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Operated By: Scenic
Ships: Scenic Amber, Scenic Amber
Departures: Dec 2024 to Dec 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Hungary (+2 more), Slovakia, Czech Republic
Exclusive Deal
INSIDE
-
RIVER VIEW
$9,945
BALCONY
$14,107
SUITE
$18,429
Save 2,600
From 9,945
View Trip
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River Cruises from Amsterdam to Prague

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