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Spain River Cruises

Are you looking for a river cruise through Spain? Choose from 78 unique river cruise itineraries to Spain, departing from Barcelona, Bilbao, Bordeaux, Lisbon, Lyon and more. April is the most popular month to cruise through Spain and we have over 1,441 departures available from seven of the world's leading river cruise lines.
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78 River Cruises (1,441 River Cruise Departures)
11 Day Portugal, Spain & the Douro River Valley with Uniworld River Cruises
River Cruise
 (5)

11 Days Porto to Lisbon
Cruise Line: Uniworld River Cruises
Ships: S.S. Sao Gabriel, S.S. Sao Rafael
Departures: May 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$3,696
Balcony
$6,153
Suite
$7,920
From
US$3,696
Save 2,450
Per Person
View Trip
11 Day Unforgettable Douro with Scenic
River Cruise
 (3)

11 Days Porto to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$7,962
Balcony
$10,063
Suite
$12,782
From
US$7,962
Save 847
Per Person
View Trip
10 Day Portugal's River of Gold with Viking River Cruises
River Cruise
 (2)

10 Days Lisbon to Porto
Cruise Line: Viking River Cruises
Ships: Viking Gyda, Viking Helgrim (+4 more), Viking Hemming, Viking Osfrid, Viking Sol, Viking Torgil
Departures: Apr 2026 to Nov 2028
Rivers: Douro
Visit: Portugal, Spain
Viking $999 Air Deal
Viking $1,299 Air Deal
Viking $1,399 Air Deal
Exclusive Savings
Inside
-
River View
$3,999
Balcony
$5,499
Suite
$6,499
From
US$3,999
Save 1,200
Per Person
View Trip
11 Day Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Lisbon to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$5,027
Balcony
$5,909
Suite
$6,983
From
US$5,027
Save 1,164
Per Person
View Trip
8 Day Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

8 Days Porto to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Mar 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$4,193
Balcony
$4,643
Suite
$6,148
From
US$4,193
Save 1,408
Per Person
View Trip
8 Day Vida Portugal: Vineyards & Villages Along the Douro with Avalon River Cruises
New ReleaseRiver Cruise
 (1)

8 Days Porto to Porto
Cruise Line: Avalon River Cruises
Ships: Avalon Alegria
Departures: Apr 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$4,213
Balcony
$6,250
Suite
-
From
US$3,926
Save 924
Per Person
View Trip
8 Day Flavors of Portugal & Spain with AmaWaterways
New ReleaseRiver Cruise

8 Days Porto to Vega de Terron
Cruise Line: AmaWaterways
Ship: AmaVida
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$3,975
Balcony
$6,278
Suite
$8,006
From
US$3,975
Save 940
Per Person
View Trip
17 Day Unforgettable Douro with Lisbon & Madrid with Scenic
River Cruise

17 Days Lisbon to Madrid
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$10,885
Balcony
$13,183
Suite
$16,672
From
US$10,885
Save 860
Per Person
View Trip
11 Day Bordeaux Affair with Madrid with Scenic
River Cruise

11 Days Bordeaux to Madrid
Cruise Line: Scenic
Ships: Scenic Diamond
Departures: Apr 2026 to Apr 2027
Rivers: Bordeaux
Visit: France, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$6,483
Balcony
$7,904
Suite
$9,194
From
US$6,483
Save 958
Per Person
View Trip
14 Day Colors of Provence with Barcelona and Paris with AmaWaterways
New ReleaseRiver Cruise

14 Days Barcelona to Paris
Cruise Line: AmaWaterways
Ship: AmaKristina
Departures: May 2026 to Oct 2026
Rivers: Rhône
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$7,515
Balcony
$8,283
Suite
$11,067
From
US$7,515
Save 803
Per Person
View Trip
11 Day Barcelona & Secrets of the Douro with Emerald Cruises
New ReleaseRiver Cruise
 (2)

11 Days Barcelona to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jun 2026 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$6,565
Balcony
$7,630
Suite
$8,810
From
US$6,565
Save 458
Per Person
View Trip
14 Day Colors of Provence with Barcelona and Paris (Christmas) with AmaWaterways
New ReleaseRiver Cruise

14 Days Barcelona to Paris
Cruise Line: AmaWaterways
Ship: AmaKristina
Departure: 07 December 2026
Rivers: Rhône
Visit: Spain, France
Exclusive Savings
Inside
-
River View
-
Balcony
$7,611
Suite
-
From
US$7,611
Save 807
Per Person
View Trip
14 Day Flavors of Portugal & Spain (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

14 Days Lisbon to Madrid
Cruise Line: AmaWaterways
Ship: AmaVida
Departures: Jul 2026 to Jul 2026
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$6,805
Balcony
$8,581
Suite
-
From
US$6,805
Save 597
Per Person
View Trip
14 Day Unforgettable Douro with Lisbon with Scenic
River Cruise

14 Days Lisbon to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$9,228
Balcony
$11,329
Suite
$14,692
From
US$9,228
Save 886
Per Person
View Trip
12 Day Exploring the Douro, plus Lisbon & Madrid - Westbound with Tauck
River Cruise

12 Days Madrid to Lisbon
Cruise Line: Tauck
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Inside
-
River View
$8,290
Balcony
$10,290
Suite
$10,990
From
US$8,290
Per Person
View Trip
11 Day Secrets of the Douro & Lisbon with Emerald Cruises
River Cruise
 (2)

11 Days Porto to Lisbon
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Mar 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$5,027
Balcony
$5,477
Suite
$7,503
From
US$5,027
Save 1,434
Per Person
View Trip
8 Day Delightful Douro with Scenic
River Cruise

8 Days Porto to Porto
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Mar 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$5,630
Balcony
$7,001
Suite
$9,412
From
US$5,630
Save 765
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian and Paris (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: Apr 2026 to Aug 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$7,286
Balcony
$8,725
Suite
$10,597
From
US$7,286
Save 853
Per Person
View Trip
14 Day Lisbon to Barcelona & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$7,131
Balcony
$8,196
Suite
$9,375
From
US$7,131
Save 489
Per Person
View Trip
11 Day Secrets of the Douro & Madrid with Emerald Cruises
River Cruise
 (2)

11 Days Porto to Madrid
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jun 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$5,145
Balcony
$12,919
Suite
$16,896
From
US$5,145
Save 1,125
Per Person
View Trip
8 Day Enticing Douro with AmaWaterways
New ReleaseRiver Cruise

8 Days Porto to Porto
Cruise Line: AmaWaterways
Ships: AmaDouro, AmaSintra
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$3,879
Balcony
$5,414
Suite
$7,910
From
US$3,879
Save 1,400
Per Person
View Trip
11 Day Madrid & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Madrid to Porto
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$5,744
Balcony
$6,809
Suite
$7,989
From
US$5,744
Save 445
Per Person
View Trip
14 Day Flavors of Portugal & Spain with Lisbon and Madrid with AmaWaterways
New ReleaseRiver Cruise

14 Days Lisbon to Madrid
Cruise Line: AmaWaterways
Ship: AmaVida
Departures: Apr 2026 to Nov 2026
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$7,429
Balcony
$8,581
Suite
$11,413
From
US$7,429
Save 597
Per Person
View Trip
11 Day Secrets of the Douro & Barcelona with Emerald Cruises
New ReleaseRiver Cruise
 (2)

11 Days Porto to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$6,151
Balcony
$7,216
Suite
$8,396
From
US$6,151
Save 458
Per Person
View Trip
15 Day Taste of Bordeaux with Madrid, San Sebastian, Loire Valley and Paris with AmaWaterways
New ReleaseRiver Cruise

15 Days Madrid to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: Apr 2026 to Oct 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$8,101
Balcony
$9,253
Suite
$10,693
From
US$8,101
Save 629
Per Person
View Trip
13 Day Unforgettable Douro with Porto with Scenic
New ReleaseRiver Cruise

13 Days Porto to Porto
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Apr 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$9,139
Balcony
$11,240
Suite
$13,820
From
US$9,139
Save 879
Per Person
View Trip
11 Day Delightful Douro with Lisbon with Scenic
River Cruise

11 Days Lisbon to Porto
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Mar 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$7,051
Balcony
$8,267
Suite
$10,677
From
US$7,051
Save 559
Per Person
View Trip
14 Day Unforgettable Douro with Madrid with Scenic
River Cruise

14 Days Porto to Madrid
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$9,816
Balcony
$11,917
Suite
$14,762
From
US$9,816
Save 821
Per Person
View Trip
14 Day Madrid to Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Madrid to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Nov 2027
Rivers: Douro
Visit: Spain, Portugal
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$6,724
Balcony
$7,789
Suite
$8,968
From
US$6,724
Save 476
Per Person
View Trip
14 Day Delightful Douro with Lisbon & Madrid with Scenic
River Cruise

14 Days Lisbon to Madrid
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Mar 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$8,552
Balcony
$10,080
Suite
$12,531
From
US$8,552
Save 610
Per Person
View Trip
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