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Spain River Cruises

Are you looking for a river cruise through Spain? Choose from 111 unique river cruise itineraries to Spain, departing from Barcelona, Bilbao, Bordeaux, Lisbon, Lyon and more. May is the most popular month to cruise through Spain and we have over 1,449 departures available from nine of the world's leading river cruise lines.
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111 River Cruises (1,449 River Cruise Departures)
8 Day Douro Discovery with Travelmarvel
River Cruise
 (6)

8 Days Porto to Porto
Cruise Line: Travelmarvel
Ship: MS Estrela
Departures: Jul 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$3,927
Balcony
$5,098
Suite
$7,744
From
A$3,927
Save 2,278
Per Person
View Trip
11 Day Lisbon with Douro Discovery with Travelmarvel
River Cruise
 (1)

11 Days Lisbon to Porto
Cruise Line: Travelmarvel
Ship: MS Estrela
Departures: Aug 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$5,889
Balcony
$7,060
Suite
$9,314
From
A$5,889
Save 1,756
Per Person
View Trip
8 Day Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

8 Days Porto to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$5,461
Balcony
$6,421
Suite
$7,823
From
A$5,461
Save 932
Per Person
View Trip
11 Day Portugal, Spain & the Douro River Valley with Uniworld River Cruises
River Cruise
 (5)

11 Days Porto to Lisbon
Cruise Line: Uniworld River Cruises
Ships: S.S. Sao Gabriel, S.S. Sao Rafael
Departures: Jul 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
The 50th Anniversary Sale
Early Booking Savings
Exclusive Savings
Inside
-
River View
$5,221
Balcony
$8,925
Suite
$10,983
From
A$5,221
Save 3,006
Per Person
View Trip
9 Day Douro Delights with APT
River Cruise
 (3)

9 Days Porto to Madrid
Cruise Line: APT
Ship: MS Estrela
Departures: Aug 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,085
Balcony
$7,746
Suite
$11,078
From
A$6,085
Save 2,616
Per Person
View Trip
11 Day Unforgettable Douro with Scenic
River Cruise
 (3)

11 Days Porto to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Economy Flight Credit
Exclusive Savings
Inside
-
River View
$8,247
Balcony
$11,677
Suite
$17,072
From
A$8,247
Save 2,688
Per Person
View Trip
10 Day Portugal's River of Gold with Viking River Cruises
River Cruise
 (2)

10 Days Lisbon to Porto
Cruise Line: Viking River Cruises
Ships: Viking Gyda, Viking Helgrim (+4 more), Viking Hemming, Viking Osfrid, Viking Sol, Viking Torgil
Departures: Jun 2026 to Nov 2028
Rivers: Douro
Visit: Portugal, Spain
Viking Savings Event
Bonus Shipboard Credit
Exclusive Savings
Inside
-
River View
$5,777
Balcony
$8,325
Suite
$9,501
From
A$5,777
Save 2,788
Per Person
View Trip
21 Day Colours of Spain with Douro Discovery with Travelmarvel
River Cruise
 (1)

21 Days Barcelona to Porto
Cruise Line: Travelmarvel
Ship: MS Estrela
Departures: Apr 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Early Booking Savings
Exclusive Savings
Inside
-
River View
$13,734
Balcony
$14,709
Suite
$16,081
From
A$13,734
Save 1,713
Per Person
View Trip
11 Day Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Lisbon to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jun 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,906
Balcony
$8,028
Suite
$10,444
From
A$6,906
Save 960
Per Person
View Trip
24 Day Spain and Portugal Delights with Douro River Cruise with APT
River Cruise
 (1)

24 Days Barcelona to Madrid
Cruise Line: APT
Ship: MS Estrela
Departures: Mar 2027 to Sep 2027
Rivers: Douro
Visit: Spain, Portugal
Early Booking Savings
Exclusive Savings
Inside
-
River View
$20,499
Balcony
$21,866
Suite
$24,414
From
A$20,499
Save 2,312
Per Person
View Trip
8 Day Vida Portugal: Vineyards & Villages Along the Douro with Avalon River Cruises
New ReleaseRiver Cruise
 (1)

8 Days Porto to Porto
Cruise Line: Avalon River Cruises
Ships: Avalon Alegria
Departures: Jun 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$6,093
Balcony
$8,421
Suite
-
From
A$5,706
Save 2,271
Per Person
View Trip
11 Day Madrid & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Madrid to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Sep 2026 to Jun 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,069
Balcony
$9,515
Suite
$11,049
From
A$8,069
Save 958
Per Person
View Trip
11 Day Barcelona & Secrets of the Douro with Emerald Cruises
New ReleaseRiver Cruise
 (2)

11 Days Barcelona to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Aug 2026 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,877
Balcony
$9,570
Suite
$13,126
From
A$8,877
Save 971
Per Person
View Trip
14 Day Lisbon to Madrid with Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Lisbon to Madrid
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jun 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,167
Balcony
$9,455
Suite
$12,234
From
A$8,167
Save 970
Per Person
View Trip
14 Day Lisbon to Barcelona & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Aug 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,867
Balcony
$10,921
Suite
$12,846
From
A$9,867
Save 991
Per Person
View Trip
14 Day Barcelona to Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Barcelona to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: May 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,259
Balcony
$11,313
Suite
$14,508
From
A$10,259
Save 999
Per Person
View Trip
14 Day Madrid to Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Madrid to Lisbon
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Sep 2026 to Jun 2027
Rivers: Douro
Visit: Spain, Portugal
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,451
Balcony
$10,897
Suite
$12,430
From
A$9,451
Save 986
Per Person
View Trip
11 Day Secrets of the Douro & Madrid with Emerald Cruises
River Cruise
 (2)

11 Days Porto to Madrid
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jun 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,951
Balcony
$8,240
Suite
$10,853
From
A$6,951
Save 942
Per Person
View Trip
11 Day Secrets of the Douro & Lisbon with Emerald Cruises
River Cruise
 (2)

11 Days Porto to Lisbon
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jul 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,676
Balcony
$7,832
Suite
$9,234
From
A$6,676
Save 960
Per Person
View Trip
11 Day Secrets of the Douro & Barcelona with Emerald Cruises
New ReleaseRiver Cruise
 (2)

11 Days Porto to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Aug 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,485
Balcony
$9,539
Suite
$11,465
From
A$8,485
Save 963
Per Person
View Trip
17 Day Unforgettable Douro with Lisbon & Madrid with Scenic
River Cruise

17 Days Lisbon to Madrid
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Economy Flight Credit + Save
Exclusive Savings
Inside
-
River View
$12,695
Balcony
$16,250
Suite
$21,645
From
A$12,695
Save 3,171
Per Person
View Trip
12 Day Exploring the Douro, plus Lisbon & Madrid - Westbound with Tauck
River Cruise

12 Days Madrid to Lisbon
Cruise Line: Tauck
Departures: Jul 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Complimentary Hotel Night
Inside
-
River View
$12,590
Balcony
$15,620
Suite
$16,680
From
A$12,590
Per Person
View Trip
8 Day Douro River Valley with Uniworld River Cruises
River Cruise

8 Days Porto to Porto
Cruise Line: Uniworld River Cruises
Ships: S.S. Sao Gabriel, S.S. Sao Rafael
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
The 50th Anniversary Sale
Early Booking Savings
Exclusive Savings
Inside
-
River View
$4,397
Balcony
$7,690
Suite
$10,091
From
A$4,397
Save 2,509
Per Person
View Trip
14 Day Essence of Portugal and Douro Discovery Journey with Travelmarvel
New ReleaseRiver Cruise

14 Days Lisbon to Porto
Cruise Line: Travelmarvel
Ships: MS Estrela
Departures: Sep 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$11,672
Balcony
$12,647
Suite
$14,019
From
A$11,672
Save 1,653
Per Person
View Trip
13 Day Delightful Douro with Lisbon & Porto with Scenic
New ReleaseRiver Cruise

13 Days Lisbon to Porto
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Apr 2027 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,881
Balcony
$12,866
Suite
-
From
A$10,881
Save 2,009
Per Person
View Trip
10 Day Douro Discovery: A Family River Cruise in Portugal plus Madrid with Tauck
River Cruise

10 Days Madrid to Porto
Cruise Line: Tauck
Departures: Jul 2026 to Jul 2027
Rivers: Douro
Visit: Spain, Portugal
Complimentary Hotel Night
Inside
-
River View
$10,290
Balcony
$13,320
Suite
$14,380
From
A$10,290
Per Person
View Trip
14 Day Flavors of Portugal & Spain with Lisbon and Madrid with AmaWaterways
New ReleaseRiver Cruise

14 Days Lisbon to Madrid
Cruise Line: AmaWaterways
Ship: AmaVida
Departures: Aug 2026 to Nov 2026
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$10,185
Balcony
$13,383
Suite
$17,964
From
A$10,185
Save 669
Per Person
View Trip
14 Day Unforgettable Douro with Lisbon with Scenic
River Cruise

14 Days Lisbon to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Economy Flight Credit
Exclusive Savings
Inside
-
River View
$10,330
Balcony
$13,760
Suite
$19,154
From
A$10,330
Save 2,730
Per Person
View Trip
8 Day Delightful Douro with Scenic
River Cruise

8 Days Porto to Porto
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Super Earlybird
Exclusive Savings
Inside
-
River View
$6,427
Balcony
$8,412
Suite
$12,351
From
A$6,427
Save 1,549
Per Person
View Trip
11 Day Enticing Douro with Lisbon (Festive Delights) with AmaWaterways
New ReleaseRiver Cruise

11 Days Lisbon to Porto
Cruise Line: AmaWaterways
Ship: AmaSintra
Departure: 17 November 2026
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$7,491
Balcony
$10,182
Suite
-
From
A$7,491
Save 1,337
Per Person
View Trip
Results: 1-30 of 111

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