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Spain River Cruises Starting In May 2026, 2027 and 2028

If you're looking at joining a river cruise through Spain in May 2026, 2027 or 2028, we have 35 unique river cruise itineraries and 1,207 departures available, operated by seven of the world's leading river cruise lines departing in May.
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35 River Cruises (1,207 River Cruise Departures)
11 Day Portugal, Spain & the Douro River Valley with Uniworld River Cruises
River Cruise
 (5)

11 Days Porto to Lisbon
Cruise Line: Uniworld River Cruises
Ships: S.S. Sao Gabriel, S.S. Sao Rafael
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
$3,696
Balcony
$6,124
Suite
$7,920
From
US$3,696
Save 2,975
Per Person
View Trip
11 Day Unforgettable Douro with Scenic
River Cruise
 (3)

11 Days Porto to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,116
Balcony
$9,372
Suite
$14,270
From
US$7,529
Save 13,566
Per Person
View Trip
10 Day Portugal's River of Gold with Viking River Cruises
River Cruise
 (2)

10 Days Lisbon to Porto
Cruise Line: Viking River Cruises
Ships: Viking Gyda, Viking Helgrim (+4 more), Viking Hemming, Viking Osfrid, Viking Sol, Viking Torgil
Departures: Apr 2026 to Nov 2028
Rivers: Douro
Visit: Portugal, Spain
Viking $999 Air Deal
Viking $1,299 Air Deal
Viking $1,399 Air Deal
Exclusive Savings
Inside
-
River View
$3,999
Balcony
$5,699
Suite
$6,499
From
US$3,999
Save 1,500
Per Person
View Trip
11 Day Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Lisbon to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,721
Balcony
$5,497
Suite
$7,708
From
US$5,138
Save 7,649
Per Person
View Trip
8 Day Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

8 Days Porto to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,692
Balcony
$4,274
Suite
$6,263
From
US$3,692
Save 8,009
Per Person
View Trip
8 Day Vida Portugal: Vineyards & Villages Along the Douro with Avalon River Cruises
New ReleaseRiver Cruise
 (1)

8 Days Porto to Porto
Cruise Line: Avalon River Cruises
Ships: Avalon Alegria
Departures: Apr 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$4,235
Balcony
$6,250
Suite
-
From
US$4,235
Save 924
Per Person
View Trip
14 Day Unforgettable Douro with Lisbon with Scenic
River Cruise

14 Days Lisbon to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,747
Balcony
$10,448
Suite
$15,347
From
US$8,605
Save 13,600
Per Person
View Trip
14 Day Madrid to Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Madrid to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Nov 2027
Rivers: Douro
Visit: Spain, Portugal
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,736
Balcony
$6,318
Suite
$8,307
From
US$5,736
Save 7,544
Per Person
View Trip
11 Day Secrets of the Douro & Lisbon with Emerald Cruises
River Cruise
 (2)

11 Days Porto to Lisbon
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jul 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,750
Balcony
$5,332
Suite
$7,320
From
US$4,750
Save 7,777
Per Person
View Trip
11 Day Madrid & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Madrid to Porto
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,873
Balcony
$5,455
Suite
$7,443
From
US$4,873
Save 7,518
Per Person
View Trip
12 Day Exploring the Douro, plus Lisbon & Madrid - Westbound with Tauck
River Cruise

12 Days Madrid to Lisbon
Cruise Line: Tauck
Departures: Mar 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Inside
-
River View
$7,990
Balcony
$9,990
Suite
$10,690
From
US$7,990
Per Person
View Trip
14 Day Barcelona to Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Barcelona to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: May 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,747
Balcony
$7,329
Suite
$9,560
From
US$6,747
Save 7,557
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian, Loire Valley and Paris (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: Mar 2026 to Aug 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$7,573
Balcony
$8,389
Suite
$9,733
From
US$7,573
Save 853
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian and Paris (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: Mar 2026 to Aug 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$7,573
Balcony
$8,389
Suite
$9,733
From
US$7,573
Save 853
Per Person
View Trip
8 Day Flavors of Portugal & Spain with AmaWaterways
New ReleaseRiver Cruise

8 Days Vega de Terron to Porto
Cruise Line: AmaWaterways
Ship: AmaVida
Departures: Mar 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Exclusive Savings
Inside
-
River View
$4,359
Balcony
$6,662
Suite
$8,486
From
US$4,359
Save 924
Per Person
View Trip
11 Day Barcelona & Secrets of the Douro with Emerald Cruises
New ReleaseRiver Cruise
 (2)

11 Days Barcelona to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jun 2026 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,884
Balcony
$6,466
Suite
$8,697
From
US$5,884
Save 7,530
Per Person
View Trip
16 Day Beautiful Bordeaux with Paris & Madrid with Scenic
River Cruise

16 Days Paris to Madrid
Cruise Line: Scenic
Ship: Scenic Diamond
Departures: Apr 2027 to Oct 2027
Rivers: Bordeaux
Visit: France, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,884
Balcony
$10,921
Suite
$12,473
From
US$8,884
Save 8,608
Per Person
View Trip
8 Day Douro River Valley with Uniworld River Cruises
River Cruise

8 Days Porto to Porto
Cruise Line: Uniworld River Cruises
Ships: S.S. Sao Gabriel, S.S. Sao Rafael
Departures: Mar 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
$3,081
Balcony
$5,586
Suite
$7,305
From
US$3,081
Save 2,713
Per Person
View Trip
8 Day Flavors of Portugal & Spain with AmaWaterways
New ReleaseRiver Cruise

8 Days Porto to Vega de Terron
Cruise Line: AmaWaterways
Ship: AmaVida
Departures: Mar 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$3,975
Balcony
$6,278
Suite
$8,006
From
US$3,975
Save 940
Per Person
View Trip
8 Day Enticing Douro with AmaWaterways
New ReleaseRiver Cruise

8 Days Porto to Porto
Cruise Line: AmaWaterways
Ships: AmaDouro, AmaSintra
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$4,263
Balcony
$5,720
Suite
$8,294
From
US$4,263
Save 940
Per Person
View Trip
17 Day Unforgettable Douro with Lisbon & Madrid with Scenic
River Cruise

17 Days Lisbon to Madrid
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Apr 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,139
Balcony
$11,864
Suite
$16,763
From
US$10,021
Save 12,660
Per Person
View Trip
11 Day Enticing Douro with Lisbon with AmaWaterways
New ReleaseRiver Cruise

11 Days Lisbon to Porto
Cruise Line: AmaWaterways
Ships: AmaDouro, AmaSintra
Departures: Mar 2026 to Sep 2026
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$5,289
Balcony
$6,728
Suite
$9,512
From
US$5,289
Save 554
Per Person
View Trip
12 Day Exploring the Douro, plus Lisbon & Madrid - Eastbound with Tauck
River Cruise

12 Days Lisbon to Madrid
Cruise Line: Tauck
Departures: May 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Inside
-
River View
$8,290
Balcony
$10,290
Suite
$10,990
From
US$8,290
Per Person
View Trip
8 Day Villages & Vintages: Cruising the Douro River Valley with Tauck
River Cruise

8 Days Porto to Porto
Cruise Line: Tauck
Departures: Apr 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Inside
-
River View
$5,990
Balcony
$7,990
Suite
$8,690
From
US$5,990
Per Person
View Trip
14 Day Flavors of Portugal & Spain with Lisbon and Madrid with AmaWaterways
New ReleaseRiver Cruise

14 Days Lisbon to Madrid
Cruise Line: AmaWaterways
Ship: AmaVida
Departures: Mar 2026 to Nov 2026
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$7,429
Balcony
$8,581
Suite
$11,413
From
US$7,429
Save 597
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian, Loire Valley and Paris with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: Mar 2026 to Oct 2026
Rivers: Bordeaux
Visit: Spain, France
Triple Savings
Exclusive Savings
Inside
-
River View
$7,526
Balcony
$8,485
Suite
$10,357
From
US$7,526
Save 1,345
Per Person
View Trip
11 Day Vida Portugal: Vineyards & Villages Along the Douro with Lisbon with Avalon River Cruises
New ReleaseRiver Cruise

11 Days Lisbon to Porto
Cruise Line: Avalon River Cruises
Ships: Avalon Alegria
Departures: Apr 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$5,482
Balcony
$7,497
Suite
-
From
US$5,482
Save 976
Per Person
View Trip
14 Day Colors of Provence with Barcelona and Paris with AmaWaterways
New ReleaseRiver Cruise

14 Days Barcelona to Paris
Cruise Line: AmaWaterways
Ship: AmaKristina
Departures: Mar 2026 to Oct 2026
Rivers: Rhône
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$7,515
Balcony
$8,379
Suite
$11,307
From
US$7,515
Save 803
Per Person
View Trip
20 Day Cruise & Tour: Discover Portugal & Spain with Uniworld River Cruises
New ReleaseRiver Cruise

20 Days Madrid to Porto
Cruise Line: Uniworld River Cruises
Ship: S.S. Sao Gabriel
Departures: May 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Exclusive Savings
Inside
-
River View
$11,155
Balcony
-
Suite
$15,907
From
US$11,155
Save 2,342
Per Person
View Trip
14 Day Beautiful Bordeaux with Madrid with Scenic
River Cruise

14 Days Bordeaux to Madrid
Cruise Line: Scenic
Ship: Scenic Diamond
Departures: Apr 2026 to Oct 2027
Rivers: Bordeaux
Visit: France, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,138
Balcony
$8,908
Suite
$10,727
From
US$7,138
Save 10,459
Per Person
View Trip
Results: 1-30 of 35

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