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Spain River Cruises Starting In May 2027 and 2028

If you're looking at joining a river cruise through Spain in May 2027 or 2028, we have 43 unique river cruise itineraries and 1,131 departures available, operated by seven of the world's leading river cruise lines departing in May.
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43 River Cruises (1,131 River Cruise Departures)
11 Day Portugal, Spain & the Douro River Valley with Uniworld River Cruises
River Cruise
 (5)

11 Days Porto to Lisbon
Cruise Line: Uniworld River Cruises
Ships: S.S. Sao Gabriel, S.S. Sao Rafael
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$3,839
Balcony
$6,159
Suite
$8,239
From
US$3,839
Save 2,250
Per Person
View Trip
11 Day Unforgettable Douro with Scenic
River Cruise
 (3)

11 Days Porto to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: May 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$6,542
Balcony
$8,774
Suite
$14,063
From
US$6,542
Save 2,753
Per Person
View Trip
10 Day Portugal's River of Gold with Viking River Cruises
River Cruise
 (2)

10 Days Lisbon to Porto
Cruise Line: Viking River Cruises
Ships: Viking Gyda, Viking Helgrim (+4 more), Viking Hemming, Viking Osfrid, Viking Sol, Viking Torgil
Departures: May 2026 to Nov 2028
Rivers: Douro
Visit: Portugal, Spain
Viking $999 Air Deal
Viking $1,299 Air Deal
Viking $1,399 Air Deal
Exclusive Savings
Inside
-
River View
$3,999
Balcony
$5,699
Suite
$6,399
From
US$3,999
Save 1,100
Per Person
View Trip
11 Day Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Lisbon to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: May 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$5,171
Balcony
$5,635
Suite
$8,041
From
US$5,171
Save 1,016
Per Person
View Trip
8 Day Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

8 Days Porto to Porto
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: May 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$4,311
Balcony
$4,775
Suite
$6,159
From
US$4,311
Save 1,037
Per Person
View Trip
8 Day Vida Portugal: Vineyards & Villages Along the Douro with Avalon River Cruises
New ReleaseRiver Cruise
 (1)

8 Days Porto to Porto
Cruise Line: Avalon River Cruises
Ships: Avalon Alegria
Departures: May 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$4,576
Balcony
$6,700
Suite
-
From
US$4,501
Save 875
Per Person
View Trip
11 Day Secrets of the Douro & Madrid with Emerald Cruises
River Cruise
 (2)

11 Days Porto to Madrid
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: May 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$5,286
Balcony
$5,750
Suite
$8,643
From
US$5,286
Save 984
Per Person
View Trip
11 Day Barcelona & Secrets of the Douro with Emerald Cruises
New ReleaseRiver Cruise
 (2)

11 Days Barcelona to Porto
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: May 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$6,749
Balcony
$7,847
Suite
$9,063
From
US$6,749
Save 266
Per Person
View Trip
11 Day Secrets of the Douro & Lisbon with Emerald Cruises
River Cruise
 (2)

11 Days Porto to Lisbon
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: Jul 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$5,171
Balcony
$5,635
Suite
$7,019
From
US$5,632
Save 1,016
Per Person
View Trip
14 Day Lisbon to Madrid with Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Lisbon to Madrid
Cruise Line: Emerald Cruises
Ships: Emerald Radiance
Departures: May 2026 to Oct 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$6,146
Balcony
$6,610
Suite
$9,653
From
US$6,146
Save 984
Per Person
View Trip
14 Day Barcelona to Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Barcelona to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: May 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$7,759
Balcony
$8,857
Suite
$10,073
From
US$7,759
Save 266
Per Person
View Trip
11 Day Madrid & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

11 Days Madrid to Porto
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Jun 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$6,329
Balcony
$7,427
Suite
$8,643
From
US$6,329
Save 266
Per Person
View Trip
14 Day Madrid to Lisbon & Secrets of the Douro with Emerald Cruises
River Cruise
 (2)

14 Days Madrid to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Radiance
Departures: Apr 2027 to Jun 2027
Rivers: Douro
Visit: Spain, Portugal
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$7,339
Balcony
$8,437
Suite
$9,653
From
US$7,339
Save 266
Per Person
View Trip
17 Day Unforgettable Douro with Lisbon & Madrid with Scenic
River Cruise

17 Days Lisbon to Madrid
Cruise Line: Scenic
Ships: Scenic Azure
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$8,922
Balcony
$11,154
Suite
$17,273
From
US$11,402
Save 2,753
Per Person
View Trip
13 Day Unforgettable Douro with Porto with Scenic
New ReleaseRiver Cruise

13 Days Porto to Porto
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Jun 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
River View
$7,387
Balcony
$11,571
Suite
-
From
US$7,387
Save 2,753
Per Person
View Trip
8 Day Flavors of Portugal & Spain with AmaWaterways
New ReleaseRiver Cruise

8 Days Vega de Terron to Porto
Cruise Line: AmaWaterways
Ships: AmaVida
Departures: Jun 2026 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Exclusive Savings
Inside
-
River View
$4,329
Balcony
$6,728
Suite
$8,628
From
US$4,329
Save 750
Per Person
View Trip
14 Day Colors of Provence with Barcelona and Paris with AmaWaterways
New ReleaseRiver Cruise

14 Days Barcelona to Paris
Cruise Line: AmaWaterways
Ship: AmaKristina
Departures: May 2026 to Oct 2026
Rivers: Rhône
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$8,068
Balcony
$8,868
Suite
$11,768
From
US$8,068
Save 500
Per Person
View Trip
14 Day Unforgettable Douro with Lisbon with Scenic
River Cruise

14 Days Lisbon to Porto
Cruise Line: Scenic
Ships: Scenic Azure
Departures: May 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Multiple Deals Available
Inside
-
River View
$7,617
Balcony
$9,849
Suite
$15,368
From
US$7,617
Save 2,753
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian, Loire Valley and Paris (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: May 2026 to Aug 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$8,128
Balcony
$9,078
Suite
-
From
US$8,128
Save 500
Per Person
View Trip
11 Day Vida Portugal: Vineyards & Villages Along the Douro with Lisbon with Avalon River Cruises
New ReleaseRiver Cruise

11 Days Lisbon to Porto
Cruise Line: Avalon River Cruises
Ships: Avalon Alegria
Departures: May 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$5,875
Balcony
$7,999
Suite
-
From
US$5,800
Save 875
Per Person
View Trip
8 Day Flavors of Portugal & Spain with AmaWaterways
New ReleaseRiver Cruise

8 Days Porto to Vega de Terron
Cruise Line: AmaWaterways
Ships: AmaVida
Departures: May 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$3,979
Balcony
$6,378
Suite
$8,328
From
US$3,979
Save 750
Per Person
View Trip
20 Day Cruise & Tour: Discover Portugal & Spain with Uniworld River Cruises
New ReleaseRiver Cruise

20 Days Madrid to Porto
Cruise Line: Uniworld River Cruises
Ship: S.S. Sao Gabriel
Departures: May 2027 to Oct 2027
Rivers: Douro
Visit: Spain, Portugal
Exclusive Savings
Inside
-
River View
$11,564
Balcony
-
Suite
$16,559
From
US$11,564
Save 1,440
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian and Paris (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: May 2026 to Aug 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$8,128
Balcony
$9,078
Suite
-
From
US$8,128
Save 500
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian and Paris with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: May 2026 to Oct 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$7,829
Balcony
$9,078
Suite
$10,778
From
US$7,829
Save 500
Per Person
View Trip
8 Day Villages & Vintages: Cruising the Douro River Valley with Tauck
River Cruise

8 Days Porto to Porto
Cruise Line: Tauck
Departures: Jun 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Inside
-
River View
$5,990
Balcony
$7,990
Suite
$8,690
From
US$5,990
Per Person
View Trip
15 Day Taste of Bordeaux with Bilbao, San Sebastian, Loire Valley and Paris with AmaWaterways
New ReleaseRiver Cruise

15 Days Bilbao to Paris
Cruise Line: AmaWaterways
Ship: AmaDolce
Departures: May 2026 to Oct 2026
Rivers: Bordeaux
Visit: Spain, France
Exclusive Savings
Inside
-
River View
$7,829
Balcony
$9,078
Suite
$10,778
From
US$7,829
Save 500
Per Person
View Trip
11 Day Enticing Douro with Lisbon with AmaWaterways
New ReleaseRiver Cruise

11 Days Lisbon to Porto
Cruise Line: AmaWaterways
Ships: AmaDouro, AmaSintra
Departures: May 2026 to Sep 2026
Rivers: Douro
Visit: Portugal, Spain
Exclusive Savings
Inside
-
River View
$5,649
Balcony
$7,848
Suite
$9,648
From
US$5,649
Save 250
Per Person
View Trip
8 Day Douro River Valley with Uniworld River Cruises
River Cruise

8 Days Porto to Porto
Cruise Line: Uniworld River Cruises
Ships: S.S. Sao Gabriel, S.S. Sao Rafael
Departures: May 2026 to Nov 2027
Rivers: Douro
Visit: Portugal, Spain
Early Booking Savings
Exclusive Savings
Inside
-
River View
$3,199
Balcony
$5,519
Suite
$7,599
From
US$3,199
Save 2,010
Per Person
View Trip
16 Day Beautiful Bordeaux with Paris & Madrid with Scenic
River Cruise

16 Days Paris to Madrid
Cruise Line: Scenic
Ship: Scenic Diamond
Departures: Apr 2027 to Oct 2027
Rivers: Bordeaux
Visit: France, Spain
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$11,150
Balcony
$13,460
Suite
$15,383
From
US$11,150
Save 751
Per Person
View Trip
16 Day Unforgettable Douro with Lisbon & Porto with Scenic
New ReleaseRiver Cruise

16 Days Lisbon to Porto
Cruise Line: Scenic
Ship: Scenic Azure
Departures: Jun 2026 to Sep 2027
Rivers: Douro
Visit: Portugal, Spain
Preferred Plus Fare + Reduced Air Offer
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
River View
$8,462
Balcony
$12,876
Suite
-
From
US$8,462
Save 2,753
Per Person
View Trip
Results: 1-30 of 43

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