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Colombia Cruises Starting In April 2026 and 2027

If you're looking at joining a cruise to Colombia in April 2026 or 2027, we have 15 unique cruise itineraries and 91 departures available, operated by four of the world's leading cruise lines departing in April.
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21 Days
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$48,390pp
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15 Cruises (91 Cruise Departures)
2 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

2 Days (1 Nights) Colon to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 18 April 2026
Visit: Panama, Colombia
Exclusive Savings
Inside
$104
Oceanview
$141
Balcony
$143
Suite
$273
From
US$104
Save 111
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2026 to Apr 2026
Visit: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$756
Oceanview
$802
Balcony
$906
Suite
$1,903
From
US$756
Save 626
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2027
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$770
Oceanview
$880
Balcony
$1,240
Suite
$1,301
From
US$770
Save 631
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) Cartagena to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Nov 2026 to Apr 2027
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$793
Oceanview
$893
Balcony
$1,282
Suite
$1,342
From
US$793
Save 488
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Jan 2027
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$775
Oceanview
$874
Balcony
$942
Suite
$1,304
From
US$775
Save 654
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 08 April 2027
Visit: USA, Colombia, Panama, Mexico
Inside
$1,919
Oceanview
$2,342
Balcony
$3,060
Suite
$9,733
From
US$1,919
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

7 Days (6 Nights) Cartagena to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 19 April 2026
Visit: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$696
Oceanview
$787
Balcony
$947
Suite
$1,637
From
US$696
Save 529
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2027
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$688
Oceanview
$726
Balcony
$1,108
Suite
$1,231
From
US$688
Save 565
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2026 to Apr 2026
Visit: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$996
Oceanview
$1,014
Balcony
$1,050
Suite
$1,480
From
US$996
Save 694
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Jan 2027
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$838
Oceanview
$958
Balcony
$1,096
Suite
$1,380
From
US$838
Save 701
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 10 April 2027
Visit: Panama, Colombia, Aruba, Bonaire, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$908
Oceanview
$1,037
Balcony
$1,477
Suite
$1,557
From
US$908
Save 501
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Miami to Seattle
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 23 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Inside
$1,777
Oceanview
$2,017
Balcony
-
Suite
$8,782
From
US$1,777
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Costa Rica, Guatemala, Mexico
Book Early & Have It All Fare Option
Inside
$2,344
Oceanview
$2,754
Balcony
$3,795
Suite
$5,942
From
US$2,344
Per Person
View Trip
21 Day Miami To Seattle with Cunard
Cruise
 (13)

21 Days (20 Nights) Miami to Seattle
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Black Friday Sale
Inside
$1,699
Oceanview
$1,899
Balcony
$1,999
Suite
$7,041
From
US$1,699
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 11 April 2027
Visit: Colombia, Aruba, Bonaire, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$950
Oceanview
$1,090
Balcony
$1,550
Suite
$1,640
From
US$950
Save 527
Per Person
View Trip
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