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Main River Cruises Starting In September 2026, 2027 and 2028

Are you planning a river cruise along the Main in September 2026, 2027 or 2028? Choose from 43 unique river cruises with 1,264 departures operated by Main's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Main river cruise that best matches your travel style, budget and dates.
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43 River Cruises (1,264 River Cruise Departures)
8 Day Medieval Treasures with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,159
Balcony
$4,694
Suite
$7,190
From
US$3,159
Save 1,400
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: Apr 2026 to Nov 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Multiple Deals Available
Inside
-
River View
$3,199
Balcony
$3,699
Suite
$4,999
From
US$3,199
Save 800
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Multiple Deals Available
Inside
-
River View
$3,199
Balcony
$3,699
Suite
$5,499
From
US$3,199
Save 500
Per Person
View Trip
14 Day Romantic Capitals: Paris to Prague - Eastbound with Tauck
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$11,590
Per Person
View Trip
8 Day Europe's Rivers & Castles with AmaWaterways
New ReleaseRiver Cruise

8 Days Nuremberg to Luxembourg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Sep 2026 to Oct 2027
Rivers: Main, Moselle
Visit: Germany, Luxembourg
Exclusive Savings
Inside
-
River View
$4,311
Balcony
$5,846
Suite
$8,342
From
US$4,311
Save 668
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
15 Day Grand European Tour with Viking River Cruises
River Cruise
 (25)

15 Days Amsterdam to Budapest
Cruise Line: Viking River Cruises
Ships: Viking Baldur, Viking Bragi (+15 more), Viking Egdir, Viking Eldir, Viking Gefjon, Viking Gymir, Viking Haki, Viking Lif, Viking Magni, Viking Mimir, Viking Rota, Viking Skadi, Viking Tir, Viking Vali, Viking Ve, Viking Vidar, Viking Vili
Departures: Mar 2026 to Nov 2028
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$6,199
Suite
$8,499
From
US$4,999
Save 3,400
Per Person
View Trip
18 Day Rhine, Main & Danube Odyssey with Viking River Cruises
New ReleaseRiver Cruise

18 Days Basel to Budapest
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: Jun 2026 to Oct 2026
Rivers: Rhine, Main, Danube
Visit: Switzerland, France, Germany, Austria, Hungary
Flights Included
Exclusive Savings
Inside
-
River View
$6,199
Balcony
$7,399
Suite
$12,649
From
US$6,199
Save 300
Per Person
View Trip
18 Day Rhine, Main & Danube Odyssey with Viking River Cruises
New ReleaseRiver Cruise

18 Days Budapest to Basel
Cruise Line: Viking River Cruises
Ships: Viking Atla, Viking Gullveig, Viking Tor
Departures: Jul 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, France, Switzerland
Flights Included
Exclusive Savings
Inside
-
River View
$6,349
Balcony
$7,799
Suite
$11,799
From
US$6,349
Save 1,650
Per Person
View Trip
15 Day Magnificent Europe with Avalon River Cruises
River Cruise
 (81)

15 Days Amsterdam to Budapest
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Illumination (+2 more), Avalon Impression, Avalon Passion
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$5,399
Balcony
$8,182
Suite
$11,830
From
US$5,399
Save 2,704
Per Person
View Trip
15 Day Magnificent Rivers of Europe with Avalon River Cruises
River Cruise
 (61)

15 Days Budapest to Amsterdam
Cruise Line: Avalon River Cruises
Ships: Avalon Expression, Avalon Illumination, Avalon Impression
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$5,783
Balcony
$8,566
Suite
$12,214
From
US$5,783
Save 2,224
Per Person
View Trip
15 Day Grand European Tour with Viking River Cruises
River Cruise
 (15)

15 Days Budapest to Amsterdam
Cruise Line: Viking River Cruises
Ships: Viking Baldur, Viking Bragi (+15 more), Viking Egdir, Viking Eldir, Viking Gefjon, Viking Gymir, Viking Haki, Viking Lif, Viking Magni, Viking Mimir, Viking Rota, Viking Skadi, Viking Tir, Viking Vali, Viking Ve, Viking Vidar, Viking Vili
Departures: Apr 2026 to Nov 2028
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$5,999
Suite
$8,499
From
US$4,999
Save 4,500
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby, Scenic Pearl
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$8,796
Suite
$12,725
From
US$6,080
Save 13,972
Per Person
View Trip
15 Day Splendours of Europe with Emerald Cruises
River Cruise
 (7)

15 Days Amsterdam to Budapest
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,946
Balcony
$5,983
Suite
$10,445
From
US$3,946
Save 13,251
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: Jun 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$5,730
Balcony
$8,514
Suite
$12,116
From
US$5,730
Save 1,190
Per Person
View Trip
15 Day European Jewels with Uniworld River Cruises
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Ships: River Duchess, S.S. Beatrice, S.S. Marlene
Departures: May 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$6,738
Balcony
$8,141
Suite
$12,116
From
US$6,738
Save 1,135
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Apr 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$9,039
Suite
$12,046
From
US$6,080
Save 13,843
Per Person
View Trip
23 Day European Sojourn with Viking River Cruises
River Cruise
 (3)

23 Days Bucharest to Amsterdam
Cruise Line: Viking River Cruises
Ships: Viking Eldir, Viking Lif, Viking Vidar
Departures: Oct 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Flights Included
Exclusive Savings
Inside
-
River View
$9,499
Balcony
$11,299
Suite
$22,999
From
US$9,499
Save 1,000
Per Person
View Trip
15 Day Splendours of Europe with Emerald Cruises
River Cruise
 (2)

15 Days Budapest to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: May 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,946
Balcony
$5,983
Suite
$10,445
From
US$3,946
Save 10,779
Per Person
View Trip
23 Day European Sojourn with Viking River Cruises
River Cruise
 (1)

23 Days Amsterdam to Bucharest
Cruise Line: Viking River Cruises
Ships: Viking Eldir, Viking Lif, Viking Vidar
Departures: May 2027 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Flights Included
Inside
-
River View
$9,499
Balcony
$11,499
Suite
$22,999
From
US$9,499
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Opal, Scenic Jasper
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,595
Balcony
$13,554
Suite
$17,875
From
US$10,988
Save 13,715
Per Person
View Trip
19 Day Jewels of Europe with Zagreb & Ljubljana with Scenic
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jasper
Departures: May 2027 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,854
Balcony
$11,813
Suite
$14,820
From
US$8,854
Save 10,105
Per Person
View Trip
18 Day Splendours of Europe & Prague with Emerald Cruises
River Cruise
 (7)

18 Days Amsterdam to Prague
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,585
Balcony
$7,622
Suite
$12,084
From
US$5,585
Save 11,031
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jasper (+5 more), Scenic Jewel, Scenic Opal, Scenic Crystal, Scenic Jade, Scenic Ruby
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,011
Balcony
$9,955
Suite
$13,884
From
US$7,011
Save 13,640
Per Person
View Trip
18 Day Prague & Splendours of Europe with Emerald Cruises
River Cruise
 (4)

18 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Destiny, Emerald Luna (+5 more), Emerald Sky, Emerald Astra, Emerald Dawn, Emerald Star, Emerald Sun
Departures: Jun 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,585
Balcony
$7,622
Suite
$12,084
From
US$5,585
Save 10,438
Per Person
View Trip
18 Day Belgium Delights & Splendours of Europe with Emerald Cruises
New ReleaseRiver Cruise
 (2)

18 Days Brussels to Budapest
Cruise Line: Emerald Cruises
Ships: Emerald Luna, Emerald Sky (+2 more), Emerald Star, Emerald Sun
Departures: Apr 2027 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Belgium, Holland, Germany, Austria, Slovakia, Hungary
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,847
Balcony
$7,884
Suite
$12,346
From
US$5,847
Save 8,774
Per Person
View Trip
24 Day Jewels of Europe with Eastern Europe Explorer with Scenic
River Cruise

24 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Jewel, Scenic Opal
Departures: May 2026 to Sep 2026
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$11,226
Balcony
$14,184
Suite
-
From
US$11,226
Save 12,761
Per Person
View Trip
25 Day Eastern European Escapade & Splendours of Europe with Emerald Cruises
River Cruise
 (2)

25 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Dawn, Emerald Luna, Emerald Sun
Departures: May 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Early Payment Discount
Exclusive Savings
Inside
-
River View
$9,077
Balcony
$11,090
Suite
$14,922
From
US$9,077
Save 9,676
Per Person
View Trip
21 Day Brussels to Prague & Splendours of Europe with Emerald Cruises
New ReleaseRiver Cruise
 (3)

21 Days Brussels to Prague
Cruise Line: Emerald Cruises
Ships: Emerald Luna, Emerald Star, Emerald Sun
Departures: Aug 2027 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Belgium, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,517
Balcony
$8,554
Suite
$13,016
From
US$6,517
Save 8,794
Per Person
View Trip
15 Day Budapest to Amsterdam by Riverboat - Northbound with Tauck
River Cruise

15 Days Budapest to Amsterdam
Cruise Line: Tauck
Departures: Jun 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Inside
-
River View
$8,390
Balcony
$9,040
Suite
$12,690
From
US$8,390
Per Person
View Trip
Results: 1-30 of 43

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