Main River Cruises Starting In October 2026, 2027 and 2028

Are you planning a river cruise along the Main in October 2026, 2027 or 2028? Choose from 48 unique river cruises with 1,277 departures operated by Main's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Main river cruise that best matches your travel style, budget and dates.
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48 River Cruises (1,277 River Cruise Departures)
River Cruise
 (1)

9 Days Basel to Nuremberg
Cruise Line: Avalon River Cruises
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,695
Balcony
$5,779
Suite
$7,863
From
US$3,695
Save 1,392
Per Person
View Trip
River Cruise
 (1)

11 Days Basel to Munich
Cruise Line: Avalon River Cruises
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$4,606
Balcony
$6,690
Suite
$8,774
From
US$4,606
Save 1,430
Per Person
View Trip
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Cruise Line: Viking River Cruises
Departures: Apr 2026 to Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Multiple Deals Available
Inside
-
River View
$3,099
Balcony
$3,499
Suite
$4,999
From
US$3,099
Save 500
Per Person
View Trip
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Departures: Apr 2026 to Nov 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Multiple Deals Available
Inside
-
River View
$3,099
Balcony
$3,499
Suite
$4,999
From
US$3,099
Save 1,700
Per Person
View Trip
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,159
Balcony
$4,694
Suite
$7,190
From
US$3,159
Save 1,400
Per Person
View Trip
New ReleaseRiver Cruise

8 Days Nuremberg to Luxembourg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Apr 2026 to Aug 2027
Rivers: Main, Moselle
Visit: Germany, Luxembourg
Exclusive Savings
Inside
-
River View
$3,447
Balcony
$4,982
Suite
$7,400
From
US$3,447
Save 1,388
Per Person
View Trip
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
New ReleaseRiver Cruise

8 Days Nuremberg to Luxembourg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Sep 2026 to Oct 2027
Rivers: Main, Moselle
Visit: Germany, Luxembourg
Exclusive Savings
Inside
-
River View
$4,071
Balcony
$5,606
Suite
$8,102
From
US$4,071
Save 908
Per Person
View Trip
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: Tauck
Departures: May 2026 to Sep 2027
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Inside
-
River View
$10,790
Balcony
$11,240
Suite
$13,790
From
US$10,790
Per Person
View Trip
New ReleaseRiver Cruise

8 Days Luxembourg to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Jul 2026 to Oct 2026
Rivers: Moselle, Main
Visit: Luxembourg, Germany
Exclusive Savings
Inside
-
River View
$4,376
Balcony
$5,528
Suite
$8,504
From
US$4,376
Save 672
Per Person
View Trip
New ReleaseRiver Cruise

14 Days Paris to Prague
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Jun 2026 to Oct 2026
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Exclusive Savings
Inside
-
River View
$6,838
Balcony
$7,990
Suite
$10,966
From
US$6,838
Save 775
Per Person
View Trip
River Cruise
 (25)

15 Days Amsterdam to Budapest
Cruise Line: Viking River Cruises
Departures: Mar 2026 to Nov 2028
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$5,799
Suite
$8,999
From
US$4,999
Save 3,000
Per Person
View Trip
New ReleaseRiver Cruise

18 Days Basel to Budapest
Cruise Line: Viking River Cruises
Departures: Apr 2026 to Oct 2026
Rivers: Rhine, Main, Danube
Visit: Switzerland, France, Germany, Austria, Hungary
Multiple Deals Available
Inside
-
River View
$6,199
Balcony
$7,549
Suite
$13,149
From
US$6,199
Save 500
Per Person
View Trip
New ReleaseRiver Cruise

18 Days Budapest to Basel
Cruise Line: Viking River Cruises
Departures: Apr 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, France, Switzerland
Flights Included
Viking $50 Air Deal
Viking $25 Air Deal
Exclusive Savings
Inside
-
River View
$6,049
Balcony
$7,999
Suite
$11,099
From
US$6,049
Save 350
Per Person
View Trip
River Cruise
 (80)

15 Days Amsterdam to Budapest
Cruise Line: Avalon River Cruises
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$5,399
Balcony
$8,182
Suite
$11,830
From
US$5,399
Save 2,704
Per Person
View Trip
River Cruise
 (61)

15 Days Budapest to Amsterdam
Cruise Line: Avalon River Cruises
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$5,399
Balcony
$8,182
Suite
$11,830
From
US$5,399
Save 2,704
Per Person
View Trip
River Cruise
 (15)

15 Days Budapest to Amsterdam
Cruise Line: Viking River Cruises
Departures: Mar 2026 to Nov 2028
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$6,099
Suite
$8,999
From
US$4,999
Save 3,500
Per Person
View Trip
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Wave Offer
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$8,796
Suite
$12,725
From
US$6,080
Save 13,972
Per Person
View Trip
River Cruise
 (7)

15 Days Amsterdam to Budapest
Cruise Line: Emerald Cruises
Departures: Feb 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
River View
$3,122
Balcony
$5,547
Suite
$9,621
From
US$3,122
Save 11,011
Per Person
View Trip
River Cruise
 (8)

15 Days Budapest to Amsterdam
Cruise Line: Uniworld River Cruises
Departures: Jun 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$6,738
Balcony
$8,658
Suite
$12,498
From
US$6,738
Save 373
Per Person
View Trip
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Departures: May 2026 to Oct 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$7,122
Balcony
$9,138
Suite
$12,978
From
US$7,122
Save 327
Per Person
View Trip
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Departures: Feb 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Wave Offer
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$7,826
Suite
$12,725
From
US$6,080
Save 13,689
Per Person
View Trip
River Cruise
 (3)

23 Days Bucharest to Amsterdam
Cruise Line: Viking River Cruises
Departures: Sep 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Flights Included
Exclusive Savings
Inside
-
River View
$9,299
Balcony
$11,299
Suite
$22,999
From
US$9,299
Save 1,000
Per Person
View Trip
River Cruise
 (2)

15 Days Budapest to Amsterdam
Cruise Line: Emerald Cruises
Departures: Feb 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
River View
$3,655
Balcony
$5,159
Suite
$9,621
From
US$3,655
Save 10,779
Per Person
View Trip
River Cruise
 (1)

23 Days Amsterdam to Bucharest
Cruise Line: Viking River Cruises
Departures: Sep 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Flights Included
Exclusive Savings
Inside
-
River View
$9,499
Balcony
$11,499
Suite
$22,999
From
US$9,499
Save 200
Per Person
View Trip
River Cruise
 (2)

25 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Departures: May 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Early Payment Discount
Exclusive Savings
Inside
-
River View
$8,423
Balcony
$10,848
Suite
$14,922
From
US$8,423
Save 9,676
Per Person
View Trip
New ReleaseRiver Cruise
 (7)

18 Days Budapest to Brussels
Cruise Line: Emerald Cruises
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland, Belgium
Wave Offer
Exclusive Savings
Inside
-
River View
$5,847
Balcony
$7,884
Suite
$12,346
From
US$5,847
Save 9,065
Per Person
View Trip
River Cruise
 (4)

18 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Departures: Apr 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
River View
$5,294
Balcony
$7,331
Suite
$11,793
From
US$5,294
Save 10,181
Per Person
View Trip
River Cruise
 (4)

18 Days Paris to Budapest
Cruise Line: Emerald Cruises
Departures: Jun 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
River View
$5,983
Balcony
$8,020
Suite
$12,482
From
US$5,983
Save 9,216
Per Person
View Trip
River Cruise
 (4)

18 Days Amsterdam to Prague
Cruise Line: Emerald Cruises
Departures: Apr 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
River View
$5,294
Balcony
$7,331
Suite
$11,793
From
US$5,294
Save 11,031
Per Person
View Trip
Results: 1-30 of 48

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