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Main River Cruises Starting In April 2026, 2027 and 2028

Are you planning a river cruise along the Main in April 2026, 2027 or 2028? Choose from 28 unique river cruises with 1,039 departures operated by Main's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Main river cruise that best matches your travel style, budget and dates.
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28 River Cruises (1,039 River Cruise Departures)
8 Day Medieval Treasures with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,159
Balcony
$4,694
Suite
$7,190
From
US$3,159
Save 1,400
Per Person
View Trip
11 Day Rhine & Main Explorer with Viking River Cruises
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Ships: Viking Modi, Viking Skirnir
Departures: Apr 2026 to Nov 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Multiple Deals Available
Inside
-
River View
$3,199
Balcony
$3,699
Suite
$4,999
From
US$3,199
Save 800
Per Person
View Trip
8 Day Europe's Rivers & Castles (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

8 Days Nuremberg to Luxembourg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Apr 2026 to Aug 2027
Rivers: Main, Moselle
Visit: Germany, Luxembourg
Exclusive Savings
Inside
-
River View
$3,447
Balcony
$4,982
Suite
$7,478
From
US$3,447
Save 1,390
Per Person
View Trip
14 Day Europe's Rivers & Castles with Prague and Paris (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: AmaWaterways
Ship: AmaPrima
Departures: Apr 2026 to Aug 2026
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Exclusive Savings
Inside
-
River View
$5,024
Balcony
$6,176
Suite
-
From
US$5,024
Save 699
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
15 Day Grand European Tour with Viking River Cruises
River Cruise
 (25)

15 Days Amsterdam to Budapest
Cruise Line: Viking River Cruises
Ships: Viking Baldur, Viking Bragi (+15 more), Viking Egdir, Viking Eldir, Viking Gefjon, Viking Gymir, Viking Haki, Viking Lif, Viking Magni, Viking Mimir, Viking Rota, Viking Skadi, Viking Tir, Viking Vali, Viking Ve, Viking Vidar, Viking Vili
Departures: Mar 2026 to Nov 2028
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$6,199
Suite
$8,499
From
US$4,999
Save 3,400
Per Person
View Trip
15 Day Grand European Tour with Viking River Cruises
River Cruise
 (15)

15 Days Budapest to Amsterdam
Cruise Line: Viking River Cruises
Ships: Viking Baldur, Viking Bragi (+15 more), Viking Egdir, Viking Eldir, Viking Gefjon, Viking Gymir, Viking Haki, Viking Lif, Viking Magni, Viking Mimir, Viking Rota, Viking Skadi, Viking Tir, Viking Vali, Viking Ve, Viking Vidar, Viking Vili
Departures: Apr 2026 to Nov 2028
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$5,999
Suite
$8,499
From
US$4,999
Save 4,500
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Pearl, Scenic Ruby
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$8,796
Suite
$12,725
From
US$6,080
Save 13,972
Per Person
View Trip
15 Day Splendours of Europe with Emerald Cruises
River Cruise
 (7)

15 Days Amsterdam to Budapest
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,946
Balcony
$5,983
Suite
$10,445
From
US$3,946
Save 13,251
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Apr 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$6,080
Balcony
$9,039
Suite
$12,046
From
US$6,080
Save 13,843
Per Person
View Trip
15 Day Splendours of Europe with Emerald Cruises
River Cruise
 (2)

15 Days Budapest to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: May 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,946
Balcony
$5,983
Suite
$10,445
From
US$3,946
Save 10,779
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Opal, Scenic Jasper
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,595
Balcony
$13,554
Suite
$17,875
From
US$10,988
Save 13,715
Per Person
View Trip
18 Day Belgium Delights & Splendours of Europe with Emerald Cruises
New ReleaseRiver Cruise
 (2)

18 Days Brussels to Budapest
Cruise Line: Emerald Cruises
Ships: Emerald Luna, Emerald Sky (+2 more), Emerald Star, Emerald Sun
Departures: Apr 2027 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Belgium, Holland, Germany, Austria, Slovakia, Hungary
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,847
Balcony
$7,884
Suite
$12,346
From
US$5,847
Save 8,774
Per Person
View Trip
23 Day Iconic Europe, from Bucharest to Amsterdam with Scenic
River Cruise

23 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade, Scenic Opal
Departures: Oct 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$12,829
Balcony
$17,776
Suite
$24,275
From
US$13,266
Save 16,272
Per Person
View Trip
21 Day Prague to Brussels & Splendours of Europe with Emerald Cruises
New ReleaseRiver Cruise
 (7)

21 Days Prague to Brussels
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn
Departures: Apr 2027 to Jun 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland, Belgium
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,656
Balcony
$9,693
Suite
$14,155
From
US$7,656
Save 8,537
Per Person
View Trip
18 Day Splendours of Europe & Belgium Delights with Emerald Cruises
New ReleaseRiver Cruise
 (7)

18 Days Budapest to Brussels
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+3 more), Emerald Luna, Emerald Sky, Emerald Star
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland, Belgium
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,138
Balcony
$8,175
Suite
$12,637
From
US$6,138
Save 8,774
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Jewel
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$9,072
Balcony
$11,449
Suite
$15,150
From
US$9,184
Save 12,076
Per Person
View Trip
29 Day Iconic Europe, from Bucharest to Amsterdam with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ships: Scenic Jade, Scenic Opal
Departures: Oct 2026 to Apr 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$15,987
Balcony
$21,624
Suite
-
From
US$17,114
Save 16,845
Per Person
View Trip
21 Day Jewels of Europe with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Jewel
Departures: Aug 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland, France
Early Booking Savings
Exclusive Savings
Inside
-
River View
$10,697
Balcony
$12,647
Suite
$16,575
From
US$10,697
Save 12,113
Per Person
View Trip
18 Day Prague & Splendours of Europe with Emerald Cruises
River Cruise
 (7)

18 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Sky, Emerald Star, Emerald Sun, Emerald Destiny, Emerald Luna
Departures: Jun 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,585
Balcony
$7,622
Suite
$12,084
From
US$5,585
Save 10,438
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+3 more), Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Early Booking Savings
Exclusive Savings
Inside
-
River View
$8,505
Balcony
$11,464
Suite
$15,392
From
US$8,505
Save 13,982
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+4 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,011
Balcony
$9,970
Suite
$13,898
From
US$7,011
Save 11,014
Per Person
View Trip
17 Day Magnificent Europe with Budapest with AmaWaterways
New ReleaseRiver Cruise

17 Days Budapest to Amsterdam
Cruise Line: AmaWaterways
Ships: AmaLea, AmaStella
Departures: Apr 2026 to Jun 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$8,380
Balcony
$11,452
Suite
-
From
US$8,380
Save 344
Per Person
View Trip
27 Day Iconic Europe, from Bucharest to Amsterdam with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Early Booking Savings
Exclusive Savings
Inside
-
River View
$14,543
Balcony
$19,054
Suite
$26,765
From
US$14,543
Save 16,773
Per Person
View Trip
19 Day Magnificent Europe with Amsterdam and Budapest with AmaWaterways
New ReleaseRiver Cruise

19 Days Amsterdam to Budapest
Cruise Line: AmaWaterways
Ships: AmaLea, AmaSofia, AmaStella
Departures: Apr 2026 to May 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$10,060
Balcony
$13,516
Suite
-
From
US$10,060
Save 554
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Early Booking Savings
Exclusive Savings
Inside
-
River View
$7,011
Balcony
$9,955
Suite
$13,884
From
US$7,011
Save 13,640
Per Person
View Trip
12 Day Cities of Light with Viking River Cruises
River Cruise
 (2)

12 Days Paris to Prague
Cruise Line: Viking River Cruises
Ships: Viking Alsvin, Viking Idi
Departures: May 2026 to Nov 2028
Rivers: Moselle, Rhine, Main
Visit: France, Luxembourg, Germany, Czech Republic
Multiple Deals Available
Inside
-
River View
$3,299
Balcony
$3,399
Suite
$4,999
From
US$3,299
Save 900
Per Person
View Trip
12 Day Cities of Light with Viking River Cruises
River Cruise
 (2)

12 Days Prague to Paris
Cruise Line: Viking River Cruises
Ships: Viking Alsvin, Viking Idi
Departures: Mar 2026 to Nov 2028
Visit: Czech Republic, Germany, Luxembourg, France
Multiple Deals Available
Inside
-
River View
$3,199
Balcony
$3,399
Suite
$4,999
From
US$3,199
Save 800
Per Person
View Trip
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