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Main River Cruises Starting In April 2026, 2027 and 2028

Are you planning a river cruise along the Main in April 2026, 2027 or 2028? Choose from 31 unique river cruises with 1,093 departures operated by Main's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Main river cruise that best matches your travel style, budget and dates.
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31 River Cruises (1,093 River Cruise Departures)
8 Day Medieval Treasures with AmaWaterways
New ReleaseRiver Cruise

8 Days Basel to Nuremberg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Mar 2027 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,159
Balcony
$4,694
Suite
$7,190
From
US$3,159
Save 1,400
Per Person
View Trip
14 Day Romantic Capitals: Prague to Paris - Westbound with Tauck
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: Tauck
Departures: Apr 2026 to Sep 2027
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Inside
-
River View
$9,790
Balcony
$10,240
Suite
$12,790
From
US$9,790
Per Person
View Trip
8 Day Europe's Rivers & Castles (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

8 Days Nuremberg to Luxembourg
Cruise Line: AmaWaterways
Ships: AmaCerto, AmaPrima
Departures: Apr 2026 to Aug 2027
Rivers: Main, Moselle
Visit: Germany, Luxembourg
Exclusive Savings
Inside
-
River View
$3,447
Balcony
$4,982
Suite
$7,478
From
US$3,447
Save 1,390
Per Person
View Trip
14 Day Europe's Rivers & Castles with Prague and Paris (Wine Cruise) with AmaWaterways
New ReleaseRiver Cruise

14 Days Prague to Paris
Cruise Line: AmaWaterways
Ship: AmaPrima
Departures: Apr 2026 to Aug 2026
Rivers: Main, Moselle
Visit: Czech Republic, Germany, Luxembourg, France
Exclusive Savings
Inside
-
River View
$6,550
Balcony
$7,702
Suite
-
From
US$6,550
Save 763
Per Person
View Trip
15 Day Grand European Tour with Viking River Cruises
River Cruise
 (25)

15 Days Amsterdam to Budapest
Cruise Line: Viking River Cruises
Ships: Viking Baldur, Viking Bragi (+15 more), Viking Egdir, Viking Eldir, Viking Gefjon, Viking Gymir, Viking Haki, Viking Lif, Viking Magni, Viking Mimir, Viking Rota, Viking Skadi, Viking Tir, Viking Vali, Viking Ve, Viking Vidar, Viking Vili
Departures: Mar 2026 to Nov 2028
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$5,999
Suite
$8,499
From
US$4,999
Save 1,450
Per Person
View Trip
15 Day Grand European Tour with Viking River Cruises
River Cruise
 (15)

15 Days Budapest to Amsterdam
Cruise Line: Viking River Cruises
Ships: Viking Baldur, Viking Bragi (+15 more), Viking Egdir, Viking Eldir, Viking Gefjon, Viking Gymir, Viking Haki, Viking Lif, Viking Magni, Viking Mimir, Viking Rota, Viking Skadi, Viking Tir, Viking Vali, Viking Ve, Viking Vidar, Viking Vili
Departures: Mar 2026 to Nov 2028
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$4,999
Balcony
$5,999
Suite
$8,499
From
US$4,999
Save 4,500
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+6 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby, Scenic Pearl
Departures: Mar 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$7,425
Balcony
$9,563
Suite
$12,767
From
US$7,425
Save 1,621
Per Person
View Trip
15 Day Splendours of Europe with Emerald Cruises
River Cruise
 (4)

15 Days Amsterdam to Budapest
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: Apr 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$4,374
Balcony
$5,957
Suite
$8,505
From
US$4,374
Save 1,183
Per Person
View Trip
15 Day Jewels of Europe with Scenic
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+5 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal, Scenic Ruby
Departures: Mar 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Multiple Deals Available
Inside
-
River View
$7,206
Balcony
$9,717
Suite
$12,179
From
US$7,206
Save 1,621
Per Person
View Trip
15 Day Splendours of Europe with Emerald Cruises
River Cruise
 (3)

15 Days Budapest to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: Apr 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$4,374
Balcony
$5,957
Suite
$8,505
From
US$4,374
Save 1,183
Per Person
View Trip
21 Day Jewels of Europe with Paris & Prague with Scenic
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Opal (+2 more), Scenic Jasper, Scenic Jewel
Departures: Jun 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Preferred Plus Fare + Free Air
Select Fare
Exclusive Savings
Inside
-
River View
$11,982
Balcony
$14,586
Suite
$18,000
From
US$13,021
Save 1,727
Per Person
View Trip
21 Day Prague to Brussels & Splendours of Europe with Emerald Cruises
New ReleaseRiver Cruise
 (7)

21 Days Prague to Brussels
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn
Departures: Apr 2027 to Jun 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland, Belgium
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$7,539
Balcony
$9,122
Suite
$11,670
From
US$7,539
Save 1,237
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+4 more), Scenic Jade, Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$8,608
Balcony
$11,118
Suite
$13,362
From
US$8,608
Save 1,651
Per Person
View Trip
34 Day Jewels of Europe with Majestic Britain & Ireland with Scenic
River Cruise

34 Days Dublin to Budapest
Cruise Line: Scenic
Ships: Scenic Crystal, Scenic Jade (+3 more), Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jul 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: Ireland, Northern Ireland, Scotland, England (+6 more), Holland, Germany, Czech Republic, Austria, Slovakia, Hungary
Exclusive Savings
Inside
-
River View
$22,689
Balcony
$25,478
Suite
$27,971
From
US$22,689
Save 912
Per Person
View Trip
18 Day Splendours of Europe & Prague with Emerald Cruises
River Cruise
 (4)

18 Days Amsterdam to Prague
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+5 more), Emerald Destiny, Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: Apr 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Multiple Deals Available
Inside
-
River View
$6,173
Balcony
$7,756
Suite
$10,304
From
US$6,173
Save 1,206
Per Person
View Trip
19 Day Magnificent Europe with Amsterdam and Budapest with AmaWaterways
New ReleaseRiver Cruise

19 Days Amsterdam to Budapest
Cruise Line: AmaWaterways
Ships: AmaLea, AmaSofia, AmaStella
Departures: Apr 2026 to Jun 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$9,868
Balcony
$13,516
Suite
$16,588
From
US$9,868
Save 554
Per Person
View Trip
18 Day Jewels of Europe with Prague with Scenic
River Cruise

18 Days Amsterdam to Prague
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jasper (+5 more), Scenic Jewel, Scenic Crystal, Scenic Jade, Scenic Opal, Scenic Ruby
Departures: Apr 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Multiple Deals Available
Inside
-
River View
$8,736
Balcony
$10,722
Suite
$13,951
From
US$8,736
Save 1,654
Per Person
View Trip
18 Day Splendours of Europe & Belgium Delights with Emerald Cruises
New ReleaseRiver Cruise
 (7)

18 Days Budapest to Brussels
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+3 more), Emerald Luna, Emerald Sky, Emerald Star
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland, Belgium
Multiple Deals Available
Inside
-
River View
$6,802
Balcony
$8,385
Suite
$10,933
From
US$6,802
Save 1,214
Per Person
View Trip
18 Day Prague & Splendours of Europe with Emerald Cruises
River Cruise
 (4)

18 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Destiny, Emerald Luna (+5 more), Emerald Sky, Emerald Astra, Emerald Dawn, Emerald Star, Emerald Sun
Departures: Apr 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$6,265
Balcony
$7,848
Suite
$10,397
From
US$6,265
Save 1,206
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Paris to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Crystal (+3 more), Scenic Jasper, Scenic Jewel, Scenic Opal
Departures: Jun 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$9,791
Balcony
$12,302
Suite
$15,134
From
US$9,791
Save 1,700
Per Person
View Trip
18 Day Belgium Delights & Splendours of Europe with Emerald Cruises
New ReleaseRiver Cruise
 (2)

18 Days Brussels to Budapest
Cruise Line: Emerald Cruises
Ships: Emerald Luna, Emerald Sky (+2 more), Emerald Star, Emerald Sun
Departures: Apr 2027 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Belgium, Holland, Germany, Austria, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$6,513
Balcony
$8,096
Suite
$10,644
From
US$6,513
Save 1,214
Per Person
View Trip
22 Day Windmills, Tulips and Belgian Delight with Jewels of Europe with Scenic
New ReleaseRiver Cruise

22 Days Amsterdam to Budapest
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jewel
Departures: Apr 2027 to Apr 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Belgium, Germany, Austria, Czech Republic, Slovakia, Hungary
Exclusive Savings
Inside
-
River View
$15,061
Balcony
$17,849
Suite
-
From
US$15,061
Save 516
Per Person
View Trip
25 Day Eastern European Escapade & Splendours of Europe with Emerald Cruises
River Cruise
 (2)

25 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Ships: Emerald Astra, Emerald Dawn (+4 more), Emerald Luna, Emerald Sky, Emerald Star, Emerald Sun
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Multiple Deals Available
Inside
-
River View
$9,227
Balcony
$10,810
Suite
$13,358
From
US$9,227
Save 1,289
Per Person
View Trip
29 Day Iconic Europe, from Bucharest to Amsterdam with Turkey with Scenic
River Cruise

29 Days Istanbul to Amsterdam
Cruise Line: Scenic
Ship: Scenic Jade
Departure: 09 April 2027
Rivers: Danube, Main, Rhine
Visit: Turkey, Bulgaria, Romania, Serbia (+7 more), Croatia, Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Exclusive Savings
Inside
-
River View
$18,766
Balcony
$23,019
Suite
$26,992
From
US$18,766
Save 544
Per Person
View Trip
27 Day Iconic Europe, from Bucharest to Amsterdam with Transylvania with Scenic
New ReleaseRiver Cruise

27 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Exclusive Savings
Inside
-
River View
$16,714
Balcony
$20,968
Suite
$24,940
From
US$16,714
Save 481
Per Person
View Trip
18 Day Jewels of Europe with Paris with Scenic
River Cruise

18 Days Budapest to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Jewel
Departures: May 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland, France
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$10,271
Balcony
$12,498
Suite
$15,025
From
US$10,272
Save 1,624
Per Person
View Trip
21 Day Jewels of Europe with Prague & Paris with Scenic
River Cruise

21 Days Prague to Paris
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade (+2 more), Scenic Jasper, Scenic Jewel
Departures: Aug 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland, France
Select Fare
Preferred Plus Fare + Free Air
Exclusive Savings
Inside
-
River View
$11,503
Balcony
$13,695
Suite
$16,733
From
US$11,503
Save 1,652
Per Person
View Trip
23 Day Iconic Europe, from Bucharest to Amsterdam with Scenic
River Cruise

23 Days Bucharest to Amsterdam
Cruise Line: Scenic
Ships: Scenic Amber, Scenic Jade
Departures: Apr 2027 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+6 more), Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Exclusive Savings
Inside
-
River View
$15,497
Balcony
$19,750
Suite
$23,723
From
US$15,497
Save 443
Per Person
View Trip
17 Day Magnificent Europe with Budapest with AmaWaterways
New ReleaseRiver Cruise

17 Days Budapest to Amsterdam
Cruise Line: AmaWaterways
Ships: AmaLea, AmaStella
Departures: Apr 2026 to Jun 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$8,380
Balcony
$11,836
Suite
$15,100
From
US$8,380
Save 352
Per Person
View Trip
12 Day Cities of Light with Viking River Cruises
River Cruise
 (2)

12 Days Paris to Prague
Cruise Line: Viking River Cruises
Ships: Viking Alsvin, Viking Idi
Departures: Mar 2026 to Nov 2028
Rivers: Moselle, Rhine, Main
Visit: France, Luxembourg, Germany, Czech Republic
Multiple Deals Available
Inside
-
River View
$3,299
Balcony
$3,399
Suite
$4,999
From
US$3,299
Save 1,900
Per Person
View Trip
Results: 1-30 of 31

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