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Cambodia River Cruises Starting In September 2027 and 2028

If you're looking at joining a river cruise through Cambodia in September 2027 or 2028, we have 62 unique river cruise itineraries and 1,003 departures available, operated by nine of the world's leading river cruise lines departing in September.
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62 River Cruises (1,003 Departures)
62 River Cruises (1,003 Departures)
Departures
Duration
8 Days
27 Days
Countries Visited
Start & End Cities
Operators
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Price
$400pp
$54,135pp
Countries
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,676
Suite
$8,632
From (Per Person)
A$6,676
Save 1,645
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,947
Suite
$4,902
From (Per Person)
A$2,947
Save 1,554
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$2,947
Suite
$4,902
From (Per Person)
A$2,947
Save 776
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,363
Suite
$9,318
From (Per Person)
A$7,853
Save 3,332
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Aug 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$4,223
Suite
$6,179
From (Per Person)
A$4,223
Save 1,600
Per Person
View Trip
20 Day Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (10)

20 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Jul 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,756
Suite
$9,711
From (Per Person)
A$7,756
Save 1,361
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,363
Suite
$9,808
From (Per Person)
A$7,853
Save 3,632
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$3,831
Suite
$6,179
From (Per Person)
A$4,223
Save 3,064
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,953
Suite
$14,712
From (Per Person)
A$12,953
Save 2,378
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$14,719
Suite
$16,380
From (Per Person)
A$14,719
Save 2,410
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,561
Suite
$14,516
From (Per Person)
A$13,247
Save 3,734
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,795
Suite
$12,260
From (Per Person)
A$10,795
Save 2,630
Per Person
View Trip
16 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (2)

16 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Aug 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,186
Suite
$8,141
From (Per Person)
A$6,186
Save 1,637
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Avalon
Ships: Avalon Saigon
Departures: Oct 2026 to Nov 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Avalon
Ships: Avalon Saigon
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,417
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Operator: Uniworld
Ships: Mekong Jewel
Departures: Nov 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$9,170
From (Per Person)
A$9,170
Save 2,601
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Oct 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,015
Suite
$11,725
From (Per Person)
A$10,015
Save 2,730
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,501
Suite
$12,064
From (Per Person)
A$10,795
Save 2,906
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,727
Suite
$9,441
From (Per Person)
A$6,374
Save 1,641
Per Person
View Trip
13 Day A Mekong Experience with Wendy Wu Tours
New ReleaseTour + River CruiseFlights Included
 (1)

13 Days Ho Chi Minh City to Siem Reap
Operator: Wendy Wu
Departures: Sep 2027 to Oct 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
From (Per Person)
A$7,634
Save 676
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
Tour + River Cruise
 (1)

24 Days Hanoi to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Sep 2027 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$18,203
Suite
$20,001
From (Per Person)
A$18,203
Save 3,361
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operator: Avalon
Ships: Avalon Saigon
Departures: Oct 2026 to Nov 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,522
Balcony
$10,414
Suite
$12,590
From (Per Person)
A$9,522
Save 1,226
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,735
Suite
$21,849
From (Per Person)
A$12,735
Save 2,760
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,735
Suite
$21,849
From (Per Person)
A$12,735
Save 2,760
Per Person
View Trip
23 Day Natural Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (1)

23 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Jul 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,444
Suite
$10,399
From (Per Person)
A$8,444
Save 1,379
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

15 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Dec 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,132
Balcony
$7,023
Suite
-
From (Per Person)
A$6,132
Save 1,632
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,340
Balcony
$6,531
Suite
$9,441
From (Per Person)
A$6,374
Save 1,641
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,870
Balcony
$10,732
Suite
$13,276
From (Per Person)
A$10,208
Save 1,229
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

17 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$8,441
Balcony
$9,034
Suite
$11,508
From (Per Person)
A$8,441
Save 1,189
Per Person
View Trip
Results: 1-30 of 62

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Trip Lengths

10 Day 3 Week

Departure Months

October November December January February March April May July August September

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City
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