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Cambodia River Cruises Starting In September 2026, 2027 and 2028

If you're looking at joining a river cruise through Cambodia in September 2026, 2027 or 2028, we have 68 unique river cruise itineraries and 1,291 departures available, operated by nine of the world's leading river cruise lines departing in September.
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68 River Cruises (1,291 Departures)
68 River Cruises (1,291 Departures)
Departures
Duration
8 Days
27 Days
Countries Visited
Start & End Cities
Operators
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Price
$2,400pp
$51,245pp
Countries
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$6,382
Suite
$8,338
From (Per Person)
A$6,382
Save 2,313
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Jul 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,457
Suite
$4,412
From (Per Person)
A$2,457
Save 1,538
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$3,733
Suite
$5,689
From (Per Person)
A$3,733
Save 2,378
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,913
Suite
$6,868
From (Per Person)
A$4,913
Save 4,282
Per Person
View Trip
20 Day Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (10)

20 Days Hanoi to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$6,874
Suite
$9,025
From (Per Person)
A$6,874
Save 3,225
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$3,733
Suite
$5,689
From (Per Person)
A$3,733
Save 2,362
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$10,993
Suite
$12,948
From (Per Person)
A$10,993
Save 3,806
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$13,053
Suite
$15,008
From (Per Person)
A$13,053
Save 3,842
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$5,697
Suite
$7,652
From (Per Person)
A$5,697
Save 3,804
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$11,679
Suite
$13,634
From (Per Person)
A$11,679
Save 3,824
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$8,443
Suite
$10,398
From (Per Person)
A$8,443
Save 4,052
Per Person
View Trip
16 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (2)

16 Days Hanoi to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$6,186
Suite
$8,141
From (Per Person)
A$6,186
Save 2,223
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$8,513
From (Per Person)
A$8,513
Save 8,081
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$8,893
Suite
$11,725
From (Per Person)
A$8,893
Save 2,704
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$8,835
Suite
$10,790
From (Per Person)
A$8,835
Save 4,060
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$5,668
Balcony
$6,531
Suite
$8,643
From (Per Person)
A$5,668
Save 1,646
Per Person
View Trip
13 Day A Mekong Experience with Wendy Wu Tours
New ReleaseTour + River CruiseFlights Included
 (1)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Wendy Wu
Departures: Sep 2026 to Oct 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
From (Per Person)
A$7,722
Save 678
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
Tour + River Cruise
 (1)

24 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$14,749
Suite
$17,669
From (Per Person)
A$14,749
Save 4,817
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$9,032
Balcony
$9,924
Suite
$12,100
From (Per Person)
A$9,032
Save 1,698
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking
Ship: Viking Saigon
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$7,247
Suite
$12,441
From (Per Person)
A$7,247
Save 8,064
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking
Ship: Viking Saigon
Departures: Sep 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$8,031
Suite
$14,597
From (Per Person)
A$8,031
Save 7,494
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$2,457
Suite
$4,412
From (Per Person)
A$2,457
Save 1,538
Per Person
View Trip
23 Day Natural Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (1)

23 Days Hanoi to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$7,856
Suite
$10,007
From (Per Person)
A$7,856
Save 3,243
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
$5,884
Balcony
$6,531
Suite
$8,951
From (Per Person)
A$5,884
Save 1,646
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$7,951
Balcony
$8,843
Suite
$11,018
From (Per Person)
A$7,951
Save 1,679
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

10 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
$5,642
Balcony
$5,798
Suite
$7,974
From (Per Person)
A$5,642
Save 617
Per Person
View Trip
13 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$5,691
Balcony
$6,582
Suite
$9,493
From (Per Person)
A$5,936
Save 1,319
Per Person
View Trip
Results: 1-30 of 68

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Trip Lengths

3 Week 10 Day

Departure Months

July August September October November December January February March April May

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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