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Cambodia River Cruises Starting In September 2026, 2027 and 2028

If you're looking at joining a river cruise through Cambodia in September 2026, 2027 or 2028, we have 45 unique river cruise itineraries and 820 departures available, operated by six of the world's leading river cruise lines departing in September.
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45 River Cruises (820 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Feb 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ship: Mekong Jewel
Departures: Mar 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,385
From
US$5,385
Save 2,614
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,586
Suite
$9,476
From
US$6,586
Save 10,367
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (5)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,024
Balcony
$5,397
Suite
$7,337
From
US$5,024
Save 7,179
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$12,372
Suite
$14,292
From
US$12,372
Save 9,094
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (5)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,520
Balcony
$7,438
Suite
$9,256
From
US$7,520
Save 7,228
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Feb 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 1,000
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Feb 2026 to Dec 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 2,000
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (5)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,621
Balcony
$5,106
Suite
$7,337
From
US$5,024
Save 7,179
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,586
Suite
$8,962
From
US$6,586
Save 12,165
Per Person
View Trip
22 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$10,867
Suite
$13,757
From
US$10,867
Save 10,434
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Uniworld River Cruises
Ship: Mekong Jewel
Departures: Mar 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,625
From
US$5,625
Save 2,622
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$5,931
Suite
$8,821
From
US$5,931
Save 12,145
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (5)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$11,277
Balcony
$5,850
Suite
$8,081
From
US$5,850
Save 7,821
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,926
Balcony
$6,411
Suite
$8,642
From
US$6,357
Save 7,210
Per Person
View Trip
18 Day Highlights of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$9,530
Suite
$11,450
From
US$9,530
Save 10,795
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$7,382
Suite
$9,061
From
US$7,382
Save 9,283
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (5)

10 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,322
Balcony
$4,807
Suite
$15,327
From
US$4,322
Save 6,825
Per Person
View Trip
22 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$12,079
Suite
$14,242
From
US$12,079
Save 10,486
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (5)

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,365
Balcony
$5,850
Suite
$8,081
From
US$5,365
Save 6,868
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$5,931
Suite
$8,821
From
US$5,931
Save 10,347
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$7,009
Suite
$8,420
From
US$7,009
Save 9,753
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Southbound) with Avalon River Cruises
River Cruise

16 Days Hanoi to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,593
From
US$6,593
Save 2,290
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (5)

21 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,035
Balcony
$7,520
Suite
$9,751
From
US$14,063
Save 7,228
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (5)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$9,895
Balcony
$4,468
Suite
$6,699
From
US$9,895
Save 6,722
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (5)

19 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$12,611
Balcony
$7,183
Suite
$9,414
From
US$7,183
Save 6,797
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,032
From
US$5,032
Save 2,242
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Feb 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$1,959
Suite
$3,704
From
US$1,959
Save 1,328
Per Person
View Trip
Results: 1-30 of 45

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Trip Lengths

10 Day

Departure Months

February March April May July August September October November December January

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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