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Cambodia River Cruises Starting In September 2027 and 2028

If you're looking at joining a river cruise through Cambodia in September 2027 or 2028, we have 64 unique river cruise itineraries and 1,021 departures available, operated by nine of the world's leading river cruise lines departing in September.
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64 River Cruises (1,021 Departures)
64 River Cruises (1,021 Departures)
Departures
Duration
8 Days
27 Days
Countries Visited
Start & End Cities
Operators
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Price
$2,400pp
$53,660pp
Countries
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,676
Suite
$8,632
From (Per Person)
A$6,676
Save 3,046
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$2,457
Suite
$4,412
From (Per Person)
A$2,457
Save 2,364
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,555
Suite
$4,216
From (Per Person)
A$2,555
Save 3,056
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,069
Suite
$8,926
From (Per Person)
A$7,069
Save 3,334
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$3,831
Suite
$5,787
From (Per Person)
A$3,831
Save 3,064
Per Person
View Trip
20 Day Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (10)

20 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Jul 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,972
Suite
$8,927
From (Per Person)
A$6,972
Save 2,123
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,559
Suite
$9,318
From (Per Person)
A$7,559
Save 3,642
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$4,223
Suite
$5,885
From (Per Person)
A$4,223
Save 3,095
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,169
Suite
$13,928
From (Per Person)
A$12,169
Save 3,732
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$13,935
Suite
$15,890
From (Per Person)
A$14,229
Save 3,774
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,561
Suite
$14,516
From (Per Person)
A$12,757
Save 3,242
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,011
Suite
$11,672
From (Per Person)
A$10,403
Save 4,088
Per Person
View Trip
16 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (2)

16 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Mar 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,186
Suite
$8,141
From (Per Person)
A$6,186
Save 1,637
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Avalon
Ship: Avalon Saigon
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Avalon
Ship: Avalon Saigon
Departures: Oct 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,417
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Operator: Uniworld
Ships: Mekong Jewel
Departures: Nov 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,199
From (Per Person)
A$10,199
Save 2,701
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,893
Suite
$11,725
From (Per Person)
A$8,893
Save 2,732
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,501
Suite
$12,358
From (Per Person)
A$10,501
Save 2,114
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,727
Suite
$9,775
From (Per Person)
A$7,354
Save 1,641
Per Person
View Trip
13 Day A Mekong Experience with Wendy Wu Tours
New ReleaseTour + River CruiseFlights Included
 (1)

13 Days Ho Chi Minh City to Siem Reap
Operator: Wendy Wu
Departures: Sep 2026 to Oct 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
From (Per Person)
A$7,634
Save 676
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
Tour + River Cruise
 (1)

24 Days Hanoi to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Jul 2027 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$17,081
Suite
$19,139
From (Per Person)
A$17,081
Save 3,347
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operator: Avalon
Ship: Avalon Saigon
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,870
Balcony
$10,732
Suite
$13,570
From (Per Person)
A$10,502
Save 1,201
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,031
Suite
$21,849
From (Per Person)
A$8,031
Save 7,464
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$9,501
Suite
$21,849
From (Per Person)
A$9,501
Save 5,994
Per Person
View Trip
23 Day Natural Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (1)

23 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Jul 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,660
Suite
$9,615
From (Per Person)
A$7,660
Save 2,141
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

15 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Dec 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$7,749
Balcony
$8,493
Suite
$10,669
From (Per Person)
A$8,337
Save 1,174
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$5,943
Balcony
$6,531
Suite
$9,775
From (Per Person)
A$5,943
Save 1,641
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (7)

10 Days Phnom Penh to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Dec 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,132
Balcony
$6,288
Suite
$8,464
From (Per Person)
A$6,132
Save 543
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,212
Balcony
$6,800
Suite
$9,686
From (Per Person)
A$6,212
Save 646
Per Person
View Trip
Results: 1-30 of 64

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Trip Lengths

10 Day 3 Week

Departure Months

September October November December January February March April May July August

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City
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