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River Cruises from Ho Chi Minh City to Siem Reap

Are you looking for a river cruise from Ho Chi Minh City to Siem Reap? April is the most popular month to river cruise between Ho Chi Minh City and Siem Reap and there are 212 departures available from four of the world's leading river cruise lines.
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Duration
8 Days
15 Days
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Price
$2,200pp
$25,395pp
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11 River Cruises (212 River Cruise Departures)
13 Day Treasures of the Mekong with Scenic
River Cruise
 (1)

13 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Oct 2025 to May 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Pay in Full SavingsExclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$6,250
SUITE
$9,230
Save (per person) 9,450
From (per person) 6,250
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Ho Chi Minh City to Siem Reap
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2025 to May 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$5,304
BALCONY
$5,799
SUITE
$8,472
Save (per person) 6,349
From (per person) 5,304
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Oct 2025 to May 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Pay in Full SavingsExclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$5,590
SUITE
$8,570
Save (per person) 9,450
From (per person) 5,590
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Mutiple Deals Available
INSIDE
-
RIVER VIEW
$5,155
BALCONY
$5,255
SUITE
$6,988
Save (per person) 6,550
From (per person) 5,155
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Avalon River Cruises
Ships: Avalon Saigon
Departures: Aug 2025 to Nov 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
-
SUITE
$4,359
Save (per person) 2,171
From (per person) 4,359
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Special Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$2,238
SUITE
$3,886
Save (per person) 853
From (per person) 2,238
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Aug 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Pay in Full SavingsExclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$11,935
SUITE
$8,670
Save (per person) 13,145
From (per person) 8,670
View Trip
10 Day Charms of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Special Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$3,449
SUITE
$4,515
Save (per person) 623
From (per person) 3,449
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2025 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
2 for 1 Fares + Pay in Full SavingsExclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$12,595
SUITE
$9,330
Save (per person) 13,145
From (per person) 9,330
View Trip
12 Day Charms of the Mekong with Ho Chi Minh City and Siem Reap with AmaWaterways
New ReleaseRiver Cruise

12 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Special Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$4,127
SUITE
$5,193
Save (per person) 644
From (per person) 4,127
View Trip
10 Day Charms of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Operated By: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Special Savings
INSIDE
-
RIVER VIEW
-
BALCONY
$3,740
SUITE
$4,806
Save (per person) 632
From (per person) 3,740
View Trip
Results: 11 results

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