Home > All River Cruises > Asia River Cruises > Mekong River Cruises > River Cruises from Ho Chi Minh City to Siem Reap

River Cruises from Ho Chi Minh City to Siem Reap

Are you looking for a river cruise from Ho Chi Minh City to Siem Reap? September, October and December are the most popular months to river cruise between Ho Chi Minh City and Siem Reap and there are 165 departures available from four of the world's leading river cruise lines.
Filter Results
Departures
Show More...
Duration
8 Days
15 Days
Operators
Price
$2,500pp
$11,960pp
Countries
Filter Results
11 River Cruises (165 River Cruise Departures)
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$6,041
Suite
$8,872
From
US$6,041
Save 360
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,571
Balcony
$5,042
Suite
$7,222
From
US$4,571
Save 238
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$4,716
Balcony
$5,187
Suite
$7,367
From
US$4,716
Save 197
Per Person
View Trip
13 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseRiver Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2027 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,361
Balcony
$4,846
Suite
$7,093
From
US$4,361
Save 197
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseRiver Cruise
 (6)

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2027 to May 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,216
Balcony
$4,701
Suite
$6,948
From
US$4,216
Save 212
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$7,848
Suite
$10,679
From
US$7,848
Save 473
Per Person
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$7,173
Suite
$10,004
From
US$7,173
Save 473
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$5,366
Suite
$8,197
From
US$5,366
Save 360
Per Person
View Trip
8 Day Charms of the Mekong (Smithsonian Journeys) with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaMaya
Departure: 25 October 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,328
Suite
$5,628
From
US$4,328
Save 250
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,324
From
US$5,324
Save 2,000
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,579
Suite
$3,928
From
US$2,579
Save 1,250
Per Person
View Trip
Results: 11 results

No trips found. Try adjusting the search filters.




River Cruises found! Scroll up to view.

Asia River Cruises

Asia River Cruises India (Ganges) River Cruises Mekong River Cruises Yangtze River Cruises

Countries

Cambodia Thailand Vietnam

Cities

River Cruises from Ho Chi Minh City

Routes

River Cruises from Hanoi to Siem Reap River Cruises from Ho Chi Minh City to Siem Reap

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations