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River Cruises from Ho Chi Minh City to Siem Reap

Are you looking for a river cruise from Ho Chi Minh City to Siem Reap? March and September are the most popular months to river cruise between Ho Chi Minh City and Siem Reap and there are 167 departures available from four of the world's leading river cruise lines.
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8 Days
15 Days
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Price
$2,100pp
$21,055pp
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11 River Cruises (167 River Cruise Departures)
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,295
Suite
$8,162
From
US$6,295
Save 11,268
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$5,882
Balcony
$4,937
Suite
$8,710
From
US$4,937
Save 7,063
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$4,783
Balcony
$5,268
Suite
$7,499
From
US$4,783
Save 7,708
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Feb 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,151
Suite
$3,686
From
US$2,151
Save 1,344
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,099
From
US$5,099
Save 2,244
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$5,640
Suite
$7,522
From
US$5,640
Save 11,249
Per Person
View Trip
10 Day Charms of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Mar 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,664
Suite
$6,295
From
US$4,664
Save 184
Per Person
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
2 for 1 Fares + Pay in Full Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$5,312
Suite
$7,620
From
US$5,312
Save 10,044
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$5,952
Suite
$8,260
From
US$5,952
Save 10,064
Per Person
View Trip
12 Day Charms of the Mekong with Ho Chi Minh City and Siem Reap with AmaWaterways
New ReleaseRiver Cruise

12 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Mar 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$5,335
Suite
$6,966
From
US$5,335
Save 212
Per Person
View Trip
10 Day Charms of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Mar 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,952
Suite
$6,583
From
US$4,952
Save 196
Per Person
View Trip
Results: 11 results

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