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Cambodia River Cruises

Are you looking for a river cruise through Cambodia? Choose from 63 unique river cruise itineraries to Cambodia, departing from Hanoi, Ho Chi Minh City, Osaka, Phnom Penh and Siem Reap. September is the most popular month to cruise through Cambodia and we have over 961 departures available from six of the world's leading river cruise lines.
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63 River Cruises (961 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,385
From
US$5,385
Save 2,614
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$6,586
Suite
$9,476
From
US$6,586
Save 10,681
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,024
Balcony
$5,106
Suite
$7,337
From
US$5,024
Save 7,179
Per Person
View Trip
24 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$12,372
Suite
$14,292
From
US$12,372
Save 11,463
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$12,372
Suite
$14,292
From
US$12,372
Save 9,094
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,520
Balcony
$7,316
Suite
$10,236
From
US$7,316
Save 7,228
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Mar 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 4,500
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Mar 2026 to Dec 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 4,500
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,642
Balcony
$3,787
Suite
$6,018
From
US$3,642
Save 7,136
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,621
Balcony
$5,106
Suite
$7,337
From
US$4,621
Save 7,179
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,032
From
US$5,032
Save 2,242
Per Person
View Trip
23 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

23 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,715
Balcony
$8,200
Suite
$10,431
From
US$7,715
Save 6,917
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,099
From
US$5,099
Save 2,244
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$7,009
Suite
$8,420
From
US$7,009
Save 11,324
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

19 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,698
Balcony
$7,183
Suite
$9,414
From
US$6,698
Save 6,282
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$3,983
Balcony
$4,468
Suite
$6,699
From
US$3,983
Save 6,825
Per Person
View Trip
13 Day Riches of the Mekong with Siem Reap and Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ship: AmaDara
Departure: 24 April 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$4,566
Suite
$5,526
From
US$4,566
Save 180
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,926
Balcony
$6,411
Suite
$8,642
From
US$5,926
Save 7,210
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Feb 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,151
Suite
$3,782
From
US$2,151
Save 1,344
Per Person
View Trip
20 Day Highlights of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

20 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$11,660
Suite
$13,581
From
US$11,660
Save 11,405
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

10 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$3,983
Balcony
$4,468
Suite
$6,699
From
US$3,983
Save 6,825
Per Person
View Trip
16 Day Riches of the Mekong with Hanoi, Ha Long Bay, Siem Reap and Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

16 Days Hanoi to Ho Chi Minh City
Cruise Line: AmaWaterways
Ship: AmaDara
Departure: 21 April 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$6,276
Suite
$7,236
From
US$6,276
Save 251
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Mar 2026 to May 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,302
Balcony
$3,787
Suite
$6,018
From
US$3,302
Save 6,518
Per Person
View Trip
23 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

23 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,376
Balcony
$7,861
Suite
$10,092
From
US$7,376
Save 6,917
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,035
Balcony
$7,520
Suite
$10,236
From
US$7,035
Save 7,228
Per Person
View Trip
22 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$10,566
Suite
$14,242
From
US$10,566
Save 12,830
Per Person
View Trip
22 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$10,867
Suite
$13,757
From
US$10,867
Save 10,434
Per Person
View Trip
Results: 1-30 of 63

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Trip Lengths

3 Week 10 Day

Departure Months

February March April May July August September October November December January

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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