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Cambodia River Cruises Starting In October 2026, 2027 and 2028

If you're looking at joining a river cruise through Cambodia in October 2026, 2027 or 2028, we have 39 unique river cruise itineraries and 718 departures available, operated by six of the world's leading river cruise lines departing in October.
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39 River Cruises (718 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,385
From
US$5,385
Save 3,247
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$6,556
Suite
$8,574
From
US$7,297
Save 1,512
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,233
Balcony
$4,900
Suite
$6,940
From
US$4,443
Save 402
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$6,823
Balcony
$6,962
Suite
$9,394
From
US$6,823
Save 412
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 800
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 1,000
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$2,914
Balcony
$3,517
Suite
$5,620
From
US$3,659
Save 359
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,233
Balcony
$4,713
Suite
$6,940
From
US$4,443
Save 363
Per Person
View Trip
22 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$10,100
Suite
$12,847
From
US$10,100
Save 790
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Southbound) with Avalon River Cruises
River Cruise

16 Days Hanoi to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,593
From
US$6,593
Save 2,290
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,032
From
US$5,032
Save 2,242
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$1,959
Suite
$3,704
From
US$1,959
Save 1,328
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

17 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$5,776
Balcony
$6,233
Suite
$8,348
From
US$5,776
Save 433
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$5,214
Suite
$7,934
From
US$5,214
Save 602
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,151
Suite
$3,782
From
US$2,151
Save 1,344
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$5,480
Balcony
$5,960
Suite
$8,186
From
US$5,776
Save 395
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$6,454
Balcony
$6,911
Suite
$9,394
From
US$6,454
Save 412
Per Person
View Trip
18 Day Highlights of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$8,904
Suite
$11,650
From
US$8,904
Save 840
Per Person
View Trip
22 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$11,022
Suite
$13,215
From
US$11,022
Save 886
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$5,214
Suite
$7,960
From
US$5,214
Save 590
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,625
From
US$5,625
Save 2,622
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$5,869
Suite
$8,574
From
US$5,869
Save 611
Per Person
View Trip
18 Day Highlights of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Apr 2026 to Oct 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$8,904
Suite
$11,489
From
US$8,904
Save 746
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,099
From
US$5,099
Save 2,244
Per Person
View Trip
23 Day Indochina Explorer and Luxury Mekong Cruise with Scenic
River Cruise

23 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Laos, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$11,890
Suite
$14,780
From
US$11,890
Save 438
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound) with Avalon River Cruises
River Cruise

16 Days Siem Reap to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,276
From
US$6,276
Save 2,277
Per Person
View Trip
26 Day Wonders of Japan, Vietnam and Cambodia with Emerald Cruises
New ReleaseRiver Cruise
 (6)

26 Days Osaka to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to Apr 2027
Rivers: Mekong
Visit: Japan, Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$14,313
Balcony
$14,769
Suite
$16,884
From
US$14,313
Save 689
Per Person
View Trip
Results: 1-30 of 39

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Trip Lengths

3 Week 10 Day

Departure Months

March April May July August September October November December January February

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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