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Cambodia River Cruises Starting In April 2027 and 2028

If you're looking at joining a river cruise through Cambodia in April 2027 or 2028, we have 57 unique river cruise itineraries and 979 departures available, operated by nine of the world's leading river cruise lines departing in April.
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57 River Cruises (979 Departures)
57 River Cruises (979 Departures)
Departures
Duration
8 Days
41 Days
Countries Visited
Start & End Cities
Operators
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Price
$2,400pp
$53,660pp
Countries
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,676
Suite
$8,632
From (Per Person)
A$6,676
Save 3,046
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$2,457
Suite
$4,412
From (Per Person)
A$2,947
Save 2,364
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,555
Suite
$4,216
From (Per Person)
A$2,947
Save 3,056
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,069
Suite
$8,926
From (Per Person)
A$7,069
Save 3,334
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$3,831
Suite
$5,787
From (Per Person)
A$4,223
Save 3,064
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,559
Suite
$9,318
From (Per Person)
A$7,559
Save 3,642
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$4,223
Suite
$5,885
From (Per Person)
A$4,223
Save 3,095
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,169
Suite
$13,928
From (Per Person)
A$12,169
Save 3,732
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$13,935
Suite
$15,890
From (Per Person)
A$14,229
Save 3,774
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,561
Suite
$14,516
From (Per Person)
A$12,561
Save 3,242
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,011
Suite
$11,672
From (Per Person)
A$10,011
Save 4,088
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Avalon
Ship: Avalon Saigon
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Avalon
Ship: Avalon Saigon
Departures: Oct 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,417
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Operator: Uniworld
Ships: Mekong Jewel
Departures: Nov 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,199
From (Per Person)
A$10,199
Save 2,701
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,893
Suite
$11,725
From (Per Person)
A$8,893
Save 2,732
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,501
Suite
$12,358
From (Per Person)
A$10,501
Save 2,114
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,727
Suite
$9,775
From (Per Person)
A$5,668
Save 1,641
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operator: Avalon
Ship: Avalon Saigon
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,870
Balcony
$10,732
Suite
$13,570
From (Per Person)
A$9,870
Save 1,201
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,031
Suite
$21,849
From (Per Person)
A$8,031
Save 7,464
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (7)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,517
Balcony
$5,575
Suite
$8,216
From (Per Person)
A$4,517
Save 606
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$5,943
Balcony
$6,531
Suite
$9,775
From (Per Person)
A$5,943
Save 1,641
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,212
Balcony
$6,800
Suite
$9,686
From (Per Person)
A$6,212
Save 646
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (7)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$4,791
Balcony
$5,379
Suite
$8,216
From (Per Person)
A$4,791
Save 617
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,938
Balcony
$6,996
Suite
$9,686
From (Per Person)
A$5,938
Save 646
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,855
Balcony
$10,718
Suite
$13,305
From (Per Person)
A$9,855
Save 1,222
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

17 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$8,171
Balcony
$9,230
Suite
$12,488
From (Per Person)
A$9,421
Save 1,183
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

17 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$8,446
Balcony
$9,034
Suite
$12,488
From (Per Person)
A$8,446
Save 1,205
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Southbound) with Avalon River Cruises
Tour + River Cruise

16 Days Hanoi to Ho Chi Minh City
Operator: Avalon
Ship: Avalon Saigon
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,333
From (Per Person)
A$10,333
Save 3,553
Per Person
View Trip
18 Day Highlights of Cambodia, Vietnam & Luxury Mekong with Scenic
Tour + River Cruise

18 Days Hanoi to Ho Chi Minh City
Operator: Scenic
Ship: Scenic Spirit
Departures: Apr 2027 to Oct 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$13,532
Suite
$16,364
From (Per Person)
A$13,532
Save 2,758
Per Person
View Trip
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Trip Lengths

10 Day 3 Week

Departure Months

September October November December January February March April May July August

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City
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