Home > All River Cruises > Asia River Cruises > Mekong River Cruises > Cambodia > April

Cambodia River Cruises Starting In April 2027 and 2028

If you're looking at joining a river cruise through Cambodia in April 2027 or 2028, we have 56 unique river cruise itineraries and 1,106 departures available, operated by nine of the world's leading river cruise lines departing in April.
Filter Results
56 River Cruises (1,106 Departures)
56 River Cruises (1,106 Departures)
Departures
Duration
8 Days
41 Days
Countries Visited
Start & End Cities
Operators
Show More...
Price
$2,100pp
$53,440pp
Countries
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,382
Suite
$8,338
From (Per Person)
A$6,382
Save 2,550
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$2,163
Suite
$4,412
From (Per Person)
A$2,555
Save 1,554
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$3,439
Suite
$5,983
From (Per Person)
A$4,027
Save 2,378
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,163
Suite
$4,118
From (Per Person)
A$2,555
Save 1,580
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,971
Suite
$8,828
From (Per Person)
A$6,971
Save 3,362
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$4,027
Suite
$5,983
From (Per Person)
A$4,027
Save 2,403
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,169
Suite
$14,124
From (Per Person)
A$12,169
Save 3,438
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$14,131
Suite
$16,086
From (Per Person)
A$14,131
Save 3,480
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,657
Suite
$9,514
From (Per Person)
A$7,657
Save 2,372
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,757
Suite
$14,614
From (Per Person)
A$12,757
Save 3,244
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$9,717
Suite
$11,672
From (Per Person)
A$9,717
Save 4,088
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,417
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Operator: Uniworld
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$7,307
From (Per Person)
A$10,199
Save 2,701
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$9,353
Suite
$11,725
From (Per Person)
A$9,353
Save 2,708
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$9,815
Suite
$12,358
From (Per Person)
A$9,815
Save 4,080
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,531
Suite
$8,643
From (Per Person)
A$5,668
Save 1,646
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operator: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ship: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,125
Balcony
$10,017
Suite
$12,193
From (Per Person)
A$9,125
Save 1,700
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,247
Suite
$12,441
From (Per Person)
A$7,247
Save 8,064
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Sep 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$8,031
Suite
$16,851
From (Per Person)
A$8,031
Save 7,494
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,517
Balcony
$5,379
Suite
$7,491
From (Per Person)
A$4,517
Save 622
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$5,884
Balcony
$6,531
Suite
$8,951
From (Per Person)
A$5,884
Save 1,646
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

21 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,811
Balcony
$10,703
Suite
$12,879
From (Per Person)
A$9,811
Save 1,700
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$4,659
Balcony
$5,379
Suite
$7,726
From (Per Person)
A$4,659
Save 622
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (6)

11 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,129
Balcony
$6,800
Suite
$9,196
From (Per Person)
A$6,129
Save 651
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (6)

11 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,938
Balcony
$6,800
Suite
$8,912
From (Per Person)
A$5,938
Save 651
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

17 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$8,044
Balcony
$8,936
Suite
$11,111
From (Per Person)
A$8,044
Save 1,681
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

17 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ship: Emerald Harmony
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$8,044
Balcony
$8,936
Suite
$11,111
From (Per Person)
A$8,044
Save 1,681
Per Person
View Trip
11 Day Spiritual Cambodia and The Mekong with APT
Tour + River Cruise

11 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$4,618
Suite
$6,573
From (Per Person)
A$4,618
Save 3,077
Per Person
View Trip
Results: 1-30 of 56

No trips found. Try adjusting the search filters.




River Cruises found! Scroll up to view.

Asia River Cruises

Asia River Cruises India (Ganges) River Cruises Mekong River Cruises Yangtze River Cruises

Trip Lengths

3 Week 10 Day

Departure Months

August September October November December January February March April May July

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations