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Cambodia River Cruises Starting In April 2027 and 2028

If you're looking at joining a river cruise through Cambodia in April 2027 or 2028, we have 58 unique river cruise itineraries and 1,033 departures available, operated by nine of the world's leading river cruise lines departing in April.
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58 River Cruises (1,033 Departures)
58 River Cruises (1,033 Departures)
Departures
Duration
8 Days
41 Days
Countries Visited
Start & End Cities
Operators
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Price
$3,300pp
$54,135pp
Countries
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,068
Suite
$9,024
From (Per Person)
A$7,068
Save 1,649
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$3,339
Suite
$5,294
From (Per Person)
A$3,339
Save 1,070
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$3,339
Suite
$5,294
From (Per Person)
A$3,339
Save 780
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Mar 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,363
Suite
$9,318
From (Per Person)
A$7,363
Save 3,332
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$4,713
Suite
$6,669
From (Per Person)
A$4,713
Save 1,604
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,147
Suite
$10,102
From (Per Person)
A$8,147
Save 1,860
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$4,713
Suite
$6,669
From (Per Person)
A$4,713
Save 1,604
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,953
Suite
$14,908
From (Per Person)
A$12,953
Save 2,418
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$15,013
Suite
$16,968
From (Per Person)
A$15,013
Save 2,450
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,561
Suite
$14,516
From (Per Person)
A$13,443
Save 3,734
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,795
Suite
$12,750
From (Per Person)
A$10,795
Save 2,600
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Avalon
Ships: Avalon Saigon
Departures: Nov 2026 to Nov 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,979
From (Per Person)
A$5,979
Save 3,575
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Avalon
Ships: Avalon Saigon
Departures: Dec 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$4,873
From (Per Person)
A$4,873
Save 3,587
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Operator: Uniworld
Ship: Mekong Jewel
Departures: Jan 2027 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,346
From (Per Person)
A$10,346
Save 2,836
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Nov 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,064
Suite
$11,725
From (Per Person)
A$10,064
Save 2,730
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,501
Suite
$12,456
From (Per Person)
A$11,285
Save 2,896
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,727
Suite
$9,775
From (Per Person)
A$5,668
Save 1,666
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operator: Avalon
Ships: Avalon Saigon
Departures: Nov 2026 to Nov 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$11,057
From (Per Person)
A$11,057
Save 3,711
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,292
Balcony
$10,184
Suite
$13,011
From (Per Person)
A$9,292
Save 1,718
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Feb 2027 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$13,323
Suite
$21,849
From (Per Person)
A$13,323
Save 380
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Nov 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$11,951
Suite
$21,849
From (Per Person)
A$11,951
Save 2,760
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (7)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,517
Balcony
$5,575
Suite
$8,618
From (Per Person)
A$4,517
Save 641
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,154
Balcony
$6,531
Suite
$9,775
From (Per Person)
A$6,154
Save 1,648
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,777
Balcony
$10,669
Suite
$13,305
From (Per Person)
A$9,777
Save 1,699
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (7)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$4,899
Balcony
$5,791
Suite
$8,618
From (Per Person)
A$4,899
Save 622
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

17 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$8,220
Balcony
$9,034
Suite
$11,940
From (Per Person)
A$9,034
Save 1,681
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,938
Balcony
$6,996
Suite
$10,044
From (Per Person)
A$5,938
Save 670
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

17 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$8,171
Balcony
$9,112
Suite
$11,940
From (Per Person)
A$8,220
Save 1,681
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,364
Balcony
$6,800
Suite
$10,044
From (Per Person)
A$6,364
Save 652
Per Person
View Trip
18 Day Highlights of Cambodia, Vietnam & Luxury Mekong with Scenic
Tour + River Cruise

18 Days Hanoi to Ho Chi Minh City
Operator: Scenic
Ship: Scenic Spirit
Departures: Nov 2026 to May 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$15,982
Suite
$18,158
From (Per Person)
A$15,982
Save 1,852
Per Person
View Trip
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Trip Lengths

10 Day 3 Week

Departure Months

October November December January February March April May July August September

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City
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