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River Cruises from Siem Reap to Ho Chi Minh City

Are you looking for a river cruise from Siem Reap to Ho Chi Minh City? September and November are the most popular months to river cruise between Siem Reap and Ho Chi Minh City and there are 239 departures available from six of the world's leading river cruise lines.
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14 River Cruises (239 Departures)
14 River Cruises (239 Departures)
Departures
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Duration
8 Days
15 Days
Operators
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Price
$2,900pp
$16,595pp
Countries
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,947
Suite
$4,902
From (Per Person)
A$2,947
Save 1,554
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,363
Suite
$9,318
From (Per Person)
A$7,363
Save 3,332
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$3,831
Suite
$6,179
From (Per Person)
A$3,831
Save 3,064
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

15 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Dec 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,132
Balcony
$7,023
Suite
-
From (Per Person)
A$6,132
Save 1,632
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,340
Balcony
$6,531
Suite
$9,441
From (Per Person)
A$6,340
Save 1,641
Per Person
View Trip
13 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Dec 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,132
Balcony
$7,023
Suite
-
From (Per Person)
A$6,132
Save 882
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,227
Balcony
$6,800
Suite
$9,294
From (Per Person)
A$6,227
Save 646
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
Tour + River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operator: Avalon
Ships: Avalon Saigon
Departures: Nov 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$7,923
From (Per Person)
A$7,923
Save 3,497
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
Tour + River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operator: Scenic
Ship: Scenic Spirit
Departures: Dec 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$8,018
Suite
$10,939
From (Per Person)
A$8,018
Save 3,729
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operator: Scenic
Ship: Scenic Spirit
Departures: Jan 2027 to Nov 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$8,893
Suite
$11,725
From (Per Person)
A$8,893
Save 2,732
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
Tour + River Cruise

15 Days Siem Reap to Ho Chi Minh City
Operator: Scenic
Ship: Scenic Spirit
Departures: Dec 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$8,082
Suite
$11,002
From (Per Person)
A$8,082
Save 4,730
Per Person
View Trip
11 Day Spiritual Cambodia and The Mekong with APT
Tour + River Cruise

11 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$6,088
Suite
$7,847
From (Per Person)
A$6,088
Save 2,611
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
Tour + River Cruise

11 Days Siem Reap to Ho Chi Minh City
Operator: Scenic
Ship: Scenic Spirit
Departures: Jan 2027 to Nov 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$8,858
Suite
$11,691
From (Per Person)
A$8,858
Save 1,732
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Operator: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Oct 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$4,497
Suite
$7,433
From (Per Person)
A$4,497
Save 1,999
Per Person
View Trip
Results: 14 results

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