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River Cruises from Siem Reap

Choose from 11 unique river cruises starting in Siem Reap, and traveling to Bangkok and Ho Chi Minh City. September and November are the most popular months to join a river cruise from Siem Reap and you can select from 186 departures available from four leading river cruise lines.
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8 Days
16 Days
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11 River Cruises (186 River Cruise Departures)
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$4,571
Balcony
$5,042
Suite
$7,222
From
US$4,571
Save 212
Per Person
View Trip
13 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseRiver Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Jul 2027 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,646
Balcony
$4,846
Suite
$7,093
From
US$4,646
Save 187
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseRiver Cruise
 (6)

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2027 to May 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,216
Balcony
$4,701
Suite
$6,948
From
US$4,216
Save 212
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$4,716
Balcony
$5,187
Suite
$7,367
From
US$4,716
Save 187
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$2,728
Suite
$3,848
From
US$2,728
Save 1,250
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound) with Avalon River Cruises
River Cruise

16 Days Siem Reap to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,529
From
US$6,529
Save 2,000
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$6,041
Suite
$8,872
From
US$6,041
Save 355
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,324
From
US$5,324
Save 2,000
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$7,173
Suite
$10,004
From
US$7,173
Save 468
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$7,848
Suite
$10,679
From
US$7,848
Save 468
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
-
Balcony
$5,366
Suite
$8,197
From
US$5,366
Save 355
Per Person
View Trip
Results: 11 results

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Asia River Cruises

Asia River Cruises India (Ganges) River Cruises Mekong River Cruises Yangtze River Cruises

Trip Lengths

3 Week 10 Day

Departure Months

July August September October November December January February March April May

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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