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River Cruises from Siem Reap

Choose from 13 unique river cruises starting in Siem Reap, and traveling to Bangkok and Ho Chi Minh City. April and September are the most popular months to join a river cruise from Siem Reap and you can select from 216 departures available from four leading river cruise lines.
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16 Days
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$22,255pp
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13 River Cruises (216 River Cruise Departures)
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$4,039
Balcony
$4,524
Suite
$6,755
From
US$4,039
Save 7,270
Per Person
View Trip
10 Day Riches of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Mar 2026 to Apr 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$3,800
Suite
$5,335
From
US$3,800
Save 172
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseRiver Cruise
 (4)

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Feb 2026 to Feb 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
$11,348
Balcony
-
Suite
-
From
US$11,348
Save 342
Per Person
View Trip
13 Day Riches of the Mekong with Siem Reap and Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Mar 2026 to Apr 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$4,567
Suite
$6,102
From
US$4,567
Save 204
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$4,730
Suite
$7,620
From
US$4,730
Save 10,064
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$5,122
Balcony
$5,268
Suite
$7,499
From
US$5,122
Save 7,347
Per Person
View Trip
11 Day Riches of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Mar 2026 to Apr 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$4,184
Suite
$5,719
From
US$4,184
Save 188
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$5,370
Suite
$8,260
From
US$5,370
Save 10,084
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$1,959
Suite
$3,704
From
US$1,959
Save 1,328
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,295
Suite
$8,162
From
US$6,295
Save 11,886
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$5,640
Suite
$7,522
From
US$5,640
Save 11,867
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,032
From
US$5,032
Save 2,242
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound) with Avalon River Cruises
River Cruise

16 Days Siem Reap to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,276
From
US$6,276
Save 2,277
Per Person
View Trip
Results: 13 results

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Asia River Cruises

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Departure Months

January February March April May July August September October November December

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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