Home > All River Cruises > Asia River Cruises > Mekong River Cruises > Vietnam > River Cruises from Ho Chi Minh City

River Cruises from Ho Chi Minh City

Choose from 25 unique river cruises starting in Ho Chi Minh City, and traveling to Bangkok, Hanoi, Phnom Penh and Siem Reap. October is the most popular month to join a river cruise from Ho Chi Minh City and you can select from 346 departures available from eight leading river cruise lines.
Filter Results
25 River Cruises (346 Departures)
25 River Cruises (346 Departures)
Departures
Show More...
Duration
8 Days
21 Days
Countries Visited
End City
Operators
Show More...
Price
$2,200pp
$21,749pp
Countries
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ship: RV Lotus
Departures: Jan 2028 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Balcony
$4,295
Suite
$6,295
From (Per Person)
US$4,295
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: APT
Ship: Mekong Serenity
Departures: Jan 2028 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Balcony
$6,895
Suite
$8,095
From (Per Person)
US$6,895
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ship: RV Lotus
Departures: Jan 2028 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Balcony
$3,195
Suite
$5,195
From (Per Person)
US$3,195
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Cruise Line: APT
Ship: Mekong Serenity
Departures: Jan 2028 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Balcony
$10,595
Suite
$11,795
From (Per Person)
US$10,595
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$3,419
From (Per Person)
US$3,419
Save 2,000
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,041
Suite
$8,872
From (Per Person)
US$6,041
Save 801
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,421
Balcony
$4,867
Suite
$6,932
From (Per Person)
US$4,421
Save 438
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River CruiseFlights Included
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking
Ship: Viking Saigon
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,999
Suite
$10,999
From (Per Person)
US$6,999
Save 1,700
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$3,241
Balcony
$3,726
Suite
$5,973
From (Per Person)
US$3,241
Save 404
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,561
Balcony
$5,007
Suite
$7,072
From (Per Person)
US$4,561
Save 358
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
River View
$6,921
Balcony
$7,367
Suite
$9,432
From (Per Person)
US$6,921
Save 438
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$3,445
Balcony
$3,940
Suite
$6,235
From (Per Person)
US$3,445
Save 197
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (6)

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,216
Balcony
$4,701
Suite
$6,948
From (Per Person)
US$4,216
Save 404
Per Person
View Trip
13 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2027 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,201
Balcony
$4,660
Suite
$6,789
From (Per Person)
US$4,201
Save 319
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
Tour + River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,324
From (Per Person)
US$5,324
Save 2,000
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
Tour + River Cruise

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,709
Suite
$10,242
From (Per Person)
US$7,709
Save 1,262
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Northbound) with Avalon River Cruises
Tour + River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia, Thailand
Exclusive Savings
Suite
$6,524
From (Per Person)
US$6,524
Save 2,000
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
Tour + River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$5,366
Suite
$8,197
From (Per Person)
US$5,366
Save 801
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,299
Suite
$3,928
From (Per Person)
US$2,299
Save 1,250
Per Person
View Trip
18 Day Journey along the Mekong with Scenic
Tour + River Cruise

18 Days Ho Chi Minh City to Bangkok
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Mar 2027 to Oct 2027
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
Balcony
$10,261
Suite
$14,415
From (Per Person)
US$10,261
Save 239
Per Person
View Trip
11 Day Spiritual Cambodia and the Mekong with APT
Tour + River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: APT
Ship: Mekong Serenity
Departures: Jan 2028 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Balcony
$5,795
Suite
$6,995
From (Per Person)
US$5,795
Per Person
View Trip
16 Day Journey along the Mekong with Scenic
Tour + River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Scenic
Ship: Scenic Spirit
Departure: 10 October 2027
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Balcony
$10,420
Suite
$13,490
From (Per Person)
US$10,420
Per Person
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
Tour + River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,034
Suite
$9,567
From (Per Person)
US$7,034
Save 1,262
Per Person
View Trip
8 Day Charms of the Mekong (Smithsonian Journeys) with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2027 to Oct 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,079
Suite
$5,628
From (Per Person)
US$4,079
Save 250
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Uniworld
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Suite
$5,999
From (Per Person)
US$5,999
Per Person
View Trip
Results: 25 results

No trips found. Try adjusting the search filters.




River Cruises found! Scroll up to view.

Asia River Cruises

Asia River Cruises India (Ganges) River Cruises Mekong River Cruises Yangtze River Cruises

Trip Lengths

3 Week 10 Day

Departure Months

July August September October November December January February March April May

Cities

Hanoi Ho Chi Minh City

Routes

Hanoi to Ho Chi Minh City Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations