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River Cruises from Ho Chi Minh City

Choose from 21 unique river cruises starting in Ho Chi Minh City, and traveling to Bangkok, Hanoi, Phnom Penh and Siem Reap. September is the most popular month to join a river cruise from Ho Chi Minh City and you can select from 384 departures available from six leading river cruise lines.
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8 Days
18 Days
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$22,540pp
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21 River Cruises (384 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,586
Suite
$9,476
From
US$6,586
Save 10,573
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (5)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,024
Balcony
$5,397
Suite
$7,337
From
US$5,024
Save 7,179
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Feb 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,999
Suite
$10,999
From
US$6,999
Save 1,000
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (5)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$3,642
Balcony
$4,078
Suite
$6,018
From
US$3,642
Save 7,136
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Uniworld River Cruises
Ship: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,625
From
US$5,625
Save 2,622
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Feb 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,151
Suite
$3,782
From
US$2,151
Save 1,344
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$5,931
Suite
$8,821
From
US$5,931
Save 10,553
Per Person
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,742
Suite
$8,420
From
US$6,742
Save 11,324
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (5)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,704
Balcony
$5,850
Suite
$8,081
From
US$5,704
Save 7,821
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (5)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$9,895
Balcony
$4,468
Suite
$6,699
From
US$4,468
Save 6,722
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,099
From
US$5,099
Save 2,244
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
New ReleaseRiver Cruise
 (5)

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,658
Balcony
$8,095
Suite
$10,326
From
US$6,658
Save 7,217
Per Person
View Trip
10 Day Charms of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Apr 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,280
Suite
$5,911
From
US$4,280
Save 196
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$7,382
Suite
$9,061
From
US$7,382
Save 9,283
Per Person
View Trip
16 Day Journey along the Mekong with Scenic
River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Feb 2026 to Oct 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Early Booking Savings
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$9,502
Suite
$12,281
From
US$9,502
Save 10,361
Per Person
View Trip
16 Day Charms of the Mekong with Ho Chi Minh City, Siem Reap, Hanoi and Ha Long Bay with AmaWaterways
New ReleaseRiver Cruise

16 Days Ho Chi Minh City to Hanoi
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Apr 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$6,469
Suite
$8,100
From
US$6,469
Save 287
Per Person
View Trip
12 Day Charms of the Mekong with Ho Chi Minh City and Siem Reap with AmaWaterways
New ReleaseRiver Cruise

12 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Apr 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,663
Suite
$6,294
From
US$4,663
Save 212
Per Person
View Trip
18 Day Journey along the Mekong with Scenic
River Cruise

18 Days Ho Chi Minh City to Bangkok
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Early Booking Savings
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$9,032
Suite
$11,923
From
US$9,032
Save 9,663
Per Person
View Trip
10 Day Charms of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Apr 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$3,992
Suite
$5,623
From
US$3,992
Save 184
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Northbound) with Avalon River Cruises
River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,363
From
US$6,363
Save 2,280
Per Person
View Trip
Results: 21 results

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Asia River Cruises

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Trip Lengths

10 Day

Departure Months

February March April May July August September October November December January

Cities

Hanoi Ho Chi Minh City

Routes

Hanoi to Ho Chi Minh City Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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