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River Cruises from Ho Chi Minh City

Choose from 21 unique river cruises starting in Ho Chi Minh City, and traveling to Bangkok, Hanoi, Phnom Penh and Siem Reap. March is the most popular month to join a river cruise from Ho Chi Minh City and you can select from 371 departures available from six leading river cruise lines.
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8 Days
18 Days
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$22,640pp
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21 River Cruises (371 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,295
Suite
$8,162
From
US$6,295
Save 10,755
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Feb 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 2,000
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$4,563
Balcony
$3,617
Suite
$7,328
From
US$3,617
Save 7,023
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$5,882
Balcony
$4,937
Suite
$8,710
From
US$4,937
Save 7,063
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Uniworld River Cruises
Ship: Mekong Jewel
Departures: Mar 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,385
From
US$5,385
Save 2,370
Per Person
View Trip
12 Day Charms of the Mekong with Ho Chi Minh City and Siem Reap with AmaWaterways
New ReleaseRiver Cruise

12 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Mar 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$5,335
Suite
$6,966
From
US$5,335
Save 212
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Northbound) with Avalon River Cruises
River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,363
From
US$6,363
Save 2,280
Per Person
View Trip
10 Day Charms of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Mar 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,664
Suite
$6,295
From
US$4,664
Save 184
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$5,952
Suite
$8,260
From
US$5,952
Save 10,064
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$4,783
Balcony
$5,268
Suite
$7,499
From
US$4,783
Save 7,708
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Wave Offer
Exclusive Savings
Inside
-
River View
$3,401
Balcony
$3,886
Suite
$6,117
From
US$3,401
Save 7,665
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
New ReleaseRiver Cruise
 (4)

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Fly Free Economy
Exclusive Savings
Inside
-
River View
$8,580
Balcony
$9,065
Suite
$11,296
From
US$8,580
Save 6,247
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$5,640
Suite
$7,522
From
US$5,640
Save 10,735
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Feb 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,151
Suite
$3,686
From
US$2,151
Save 1,344
Per Person
View Trip
10 Day Charms of the Mekong with Siem Reap with AmaWaterways
New ReleaseRiver Cruise

10 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Mar 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,952
Suite
$6,583
From
US$4,952
Save 196
Per Person
View Trip
16 Day Journey along the Mekong with Scenic
River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: May 2026 to Oct 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Wave Offer
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$8,968
Suite
$10,380
From
US$8,968
Save 9,442
Per Person
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
2 for 1 Fares + Pay in Full Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$5,312
Suite
$7,620
From
US$5,312
Save 10,044
Per Person
View Trip
18 Day Journey along the Mekong with Scenic
River Cruise

18 Days Ho Chi Minh City to Bangkok
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Multiple Deals Available
Inside
-
River View
-
Balcony
$8,741
Suite
$11,632
From
US$8,741
Save 9,112
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,099
From
US$5,099
Save 2,244
Per Person
View Trip
16 Day Charms of the Mekong with Ho Chi Minh City, Siem Reap, Hanoi and Ha Long Bay with AmaWaterways
New ReleaseRiver Cruise

16 Days Ho Chi Minh City to Hanoi
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Feb 2026 to Mar 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$7,141
Suite
$8,772
From
US$7,141
Save 287
Per Person
View Trip
Results: 21 results

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Asia River Cruises

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Trip Lengths

10 Day

Departure Months

January February March April May July August September October November December

Cities

Hanoi Ho Chi Minh City

Routes

Hanoi to Ho Chi Minh City Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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