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All South America Tour & Cruise Packages

Compare 63 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
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63 Packages (367 Departures)
63 Packages (367 Departures)
Departures
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Duration
7 Days
37 Days
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Price
$5,100pp
$82,205pp
11 Day Antarctica: The White Continent with Collette
Tour + Cruise

11 Days Buenos Aires to Buenos Aires
Operator: Collette
Departures: Dec 2027 to Mar 2028
Trip Styles: Coach, Small Group, Cruise, Wildlife, Scenic
Visits: Chile, Argentina, Antarctica
From (Per Person)
US$15,399
Per Person
View Trip
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Tour Operator: Cosmos
Departures: Sep 2026 to Oct 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
From (Per Person)
US$11,994
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Cruise Line: Holland America
Tour Operator: Travelmarvel
Departures: Feb 2027 to Feb 2028
Trip Styles: Coach, Cruise, Scenic
Visits: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Oceanview
$13,795
Balcony
$15,085
From (Per Person)
US$13,795
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Tour Operator: Cosmos
Departures: Sep 2026 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
US$10,482
Per Person
View Trip
17 Day Antarctica & Iguazu Falls Delight - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

17 Days Buenos Aires to Buenos Aires
Tour Operator: Scenic
Ship: Scenic Ikon
Departures: Jan 2029 to Feb 2029
Trip Styles: Coach, Cruise, Scenic
Visits: Argentina, Antarctica, Brazil
Balcony
$31,485
Suite
$34,730
From (Per Person)
US$31,485
Per Person
View Trip
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Tour Operator: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Visits: Chile, Argentina, Antarctica
Balcony
$45,650
Suite
$51,810
From (Per Person)
US$45,650
Per Person
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Tour Operator: Cosmos
Departures: Oct 2026 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
From (Per Person)
US$8,568
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operator: Collette
Departures: Oct 2026 to Mar 2027
Trip Styles: Adventure, Coach, Small Group, Cruise, Scenic
Visits: Argentina, Chile
Exclusive Savings
From (Per Person)
US$10,199
Save 350
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Tour Operator: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Jan 2028
Trip Styles: Coach, Cruise, Scenic
Visits: Chile, Argentina, Antarctica
Exclusive Savings
Balcony
$38,149
Suite
$43,897
From (Per Person)
US$38,149
Save 3,676
Per Person
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Tour + Cruise

8 Days Quito to Guayaquil
Tour Operator: Tauck
Departure: 22 December 2026
Trip Styles: Coach, Cruise, Family, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
From (Per Person)
US$7,490
Per Person
View Trip
37 Day Machu Picchu, Amazon & Antarctic Odyssey - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

37 Days Lima to Buenos Aires
Tour Operator: Scenic
Ship: Scenic Eclipse II
Departure: 26 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visits: Peru, Argentina, Falkland Islands, South Georgia Island, Antarctica
Balcony
$82,205
Suite
$103,205
From (Per Person)
US$82,205
Per Person
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Cruise Line: Seabourn
Tour Operator: APT
Ships: Seabourn Venture
Departures: Feb 2027 to Feb 2028
Trip Styles: Cruise, Scenic
Visits: Chile, Argentina, Antarctica
Balcony
$20,495
Suite
$21,995
From (Per Person)
US$20,495
Per Person
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Tour Operator: Trafalgar
Departure: 31 October 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
US$7,325
Save 150
Per Person
View Trip
7 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Tour Operator: Globus
Departures: Aug 2026 to Dec 2027
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos
From (Per Person)
US$5,199
Per Person
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Tour Operator: Globus
Departures: Feb 2027 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
US$15,402
Save 250
Per Person
View Trip
26 Day Best of South America with Galápagos Cruise with APT
New ReleaseTour + Cruise

26 Days Rio de Janeiro to Guayaquil
Tour Operator: APT
Departures: Apr 2027 to Nov 2028
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
From (Per Person)
US$24,795
Per Person
View Trip
32 Day Antarctic Voyage with Galápagos and Peru with APT
New ReleaseTour + Cruise

32 Days Quito to Buenos Aires
Cruise Line: Seabourn
Tour Operator: APT
Ship: Seabourn Venture
Departure: 31 January 2028
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Visits: Ecuador, Galapagos, Peru, Argentina, Antarctica
Balcony
$34,495
Suite
$36,395
From (Per Person)
US$34,495
Per Person
View Trip
17 Day Mysteries of the Inca Empire with Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Tour Operator: Cosmos
Departures: Oct 2026 to Dec 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
US$7,176
Save 150
Per Person
View Trip
31 Day Best of South America with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

31 Days Rio de Janeiro to Guayaquil
Tour Operator: APT
Departures: May 2027 to Oct 2028
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
From (Per Person)
US$31,495
Per Person
View Trip
29 Day Best of South America with Amazon & Galápagos Cruises with APT
Tour + Cruise

29 Days Rio de Janeiro to Guayaquil
Tour Operator: APT
Ship: Delfin III
Departures: Feb 2028 to Sep 2028
Trip Styles: Small Group, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Suite
$32,195
From (Per Person)
US$32,195
Per Person
View Trip
30 Day Antarctic Voyage with Peru and Amazon Cruise with APT
New ReleaseTour + Cruise

30 Days Lima to Buenos Aires
Tour Operator: APT
Ships: Seabourn Venture, Delfin III
Departure: 25 January 2027
Trip Styles: Cruise, Wildlife, Scenic
Visits: Peru, Argentina, Antarctica
Balcony
$29,595
Suite
$31,095
From (Per Person)
US$29,595
Per Person
View Trip
23 Day Antarctic Voyage with Chile and Brazil Highlights with APT
New ReleaseTour + Cruise

23 Days Santiago to Rio de Janeiro
Cruise Line: Seabourn
Tour Operator: APT
Ship: Seabourn Venture
Departure: 14 February 2028
Trip Styles: Cruise, Scenic
Visits: Chile, Argentina, Antarctica, Brazil
Balcony
$25,445
Suite
$27,345
From (Per Person)
US$25,445
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Tour Operator: G Adventures
Departures: Dec 2026 to Dec 2027
Trip Styles: Adventure, Small Group, Cruise, Island Hopping, Wildlife
Visits: Peru, Ecuador, Galapagos
From (Per Person)
US$8,929
Per Person
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Tour Operator: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visits: Peru, Chile, Argentina
Balcony
$50,755
Suite
-
From (Per Person)
US$50,755
Per Person
View Trip
24 Day Antarctic Voyage with Peru with APT
New ReleaseTour + Cruise

24 Days Lima to Buenos Aires
Cruise Line: Seabourn
Tour Operator: APT
Ship: Seabourn Venture
Departure: 08 February 2028
Trip Styles: Cruise, Scenic
Visits: Peru, Argentina, Antarctica
Balcony
$24,095
Suite
$25,995
From (Per Person)
US$24,095
Per Person
View Trip
15 Day Spirit of Peru with Galápagos Cruise with APT
New ReleaseTour + Cruise

15 Days Lima to Guayaquil
Tour Operator: APT
Departures: May 2027 to Nov 2028
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife, Scenic
Visits: Peru, Ecuador, Galapagos
From (Per Person)
US$15,395
Per Person
View Trip
21 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

21 Days Rio de Janeiro to Buenos Aires
Tour Operator: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I, Scenic Ikon
Departures: Jan 2027 to Jan 2029
Trip Styles: Coach, Cruise, Scenic
Visits: Brazil, Argentina, Antarctica
Balcony
$31,930
Suite
$35,330
From (Per Person)
US$31,930
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Tour Operator: Globus
Departures: Feb 2027 to Nov 2027
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Visits: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From (Per Person)
US$13,447
Save 250
Per Person
View Trip
28 Day Antarctica, South Georgia, Argentina & Brazil - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

28 Days Rio de Janeiro to Buenos Aires
Tour Operator: Scenic
Ships: Scenic Eclipse I
Departures: Feb 2028 to Jan 2029
Trip Styles: Coach, Cruise, Scenic
Visits: Brazil, Argentina, Falkland Islands, South Georgia Island, Antarctica
Exclusive Savings
Balcony
$40,855
Suite
$52,195
From (Per Person)
US$40,855
Save 5,970
Per Person
View Trip
29 Day Antarctic Voyage with South American Discovery with APT
Tour + Cruise

29 Days Lima to Rio de Janeiro
Cruise Line: Seabourn
Tour Operator: APT
Ship: Seabourn Venture
Departure: 08 February 2028
Trip Styles: Cruise, Scenic
Visits: Peru, Argentina, Antarctica, Brazil
Balcony
$28,645
Suite
$30,545
From (Per Person)
US$28,645
Per Person
View Trip
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