All South America Tour & Cruise Packages

Compare 32 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
Filter Results
Departures
Show More...
Duration
7 Days
33 Days
Countries
Show More...
Budget
Ship Size
Start & End Cities
Operators
Show More...
Price
$6,600pp
$59,285pp
Filter Results
32 Packages (215 Package Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Save Map View
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2026
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 264
From 15,892
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Save Map View
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Mar 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Brazil, Argentina, Uruguay, Falkland Islands (+2 more), Chile, Peru
Exclusive Deal
Save 1,544
From 17,256
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Save Map View
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save 1,546
From 16,955
26 Day Spirit of South America with Brazil Amazon and Galapagos Cruise with Globus
Save Map View
Tour + Cruise
 (1)

26 Days Manaus to Guayaquil
Operated By: Globus
Departure: 13 September 2024
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 295
From 18,726
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Save Map View
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2026
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 227
From 13,877
17 Day Peru Splendors with Peru Amazon & Galapagos Cruise with Globus
Save Map View
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Aug 2024 to Nov 2024
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 187
From 11,922
15 Day Peru & Galapagos by Yacht with Collette
Save Map View
Tour + Cruise

15 Days Lima to Quito
Operated By: Collette
Departures: Sep 2024 to Mar 2025
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 192
From 11,213
17 Day Mysteries of the Inca Empire with a Galapagos Cruise with Cosmos
Save Map View
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2024 to Dec 2026
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 170
From 9,923
14 Day Highlights Of South America – Land And Sea Expedition with Hurtigruten
Save Map View
Tour + Cruise

14 Days Colon to Lima
Operated By: Hurtigruten
Ship: MS Fram
Departure: 06 October 2024
Countries Visited: Panama, Ecuador, Peru
Exclusive Deal
INSIDE
$19,313
OCEANVIEW
$20,598
BALCONY
-
SUITE
$22,835
Save 2,357
From 19,313
12 Day Wonders of the Galápagos & Machu Picchu: Eastern Islands Route with Abercrombie & Kent
Save Map View
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Apr 2025 to Oct 2025
Countries Visited: Ecuador, Galapagos, Peru
From 27,245
13 Day Journey to Antarctica: The White Continent with Collette
Save Map View
Tour + Cruise

13 Days Santiago to Santiago
Operated By: Collette
Departure: 18 February 2025
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Exclusive Savings
Save 468
From 25,591
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
Save Map View
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Oct 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 142
From 6,892
29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
Save Map View
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2026
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 252
From 15,361
16 Day Hidden Galapagos & Peru with Tauck
Save Map View
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Mar 2025 to Oct 2025
Countries Visited: Peru, Ecuador, Galapagos
From 25,740
22 Day Spirit of South America with Galapagos Cruise with Globus
Save Map View
Tour + Cruise

22 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Oct 2024
Countries Visited: Brazil, Argentina, Peru, Galapagos (+1 more), Ecuador
Exclusive Savings
Save 258
From 16,345
12 Day Wonders of the Galápagos & Machu Picchu: Northern Islands Route with Abercrombie & Kent
Save Map View
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Feb 2025 to Nov 2025
Countries Visited: Ecuador, Galapagos, Peru
From 26,465
14 Day Pure Antarctica with Travelmarvel
Save Map View
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Travelmarvel
Departure: 09 November 2025
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Argentina, Antarctica
Exclusive Deal
Save 1,877
From 13,018
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Save Map View
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Sep 2024 to Nov 2024
Countries Visited: Peru, Ecuador
Exclusive Savings
From 12,389
15 Day Peru & the Galapagos Islands with Tauck
Save Map View
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Sep 2024 to Oct 2025
Countries Visited: Peru, Ecuador, Galapagos
From 19,700
23 Day Legacy of the Incas with Peru Amazon & Galapagos Cruise with Globus
Save Map View
Tour + Cruise

23 Days Lima to Guayaquil
Operated By: Globus
Departure: 20 September 2024
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 279
From 17,578
25 Day Spirit of South America with Santiago and Galapagos Cruise with Globus
Save Map View
Tour + Cruise

25 Days Santiago to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Oct 2024
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 277
From 17,883
30 Day Best of South America with Amazon and Galapagos Cruises with APT
Save Map View
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Apr 2025 to Sep 2025
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save 3,333
From 39,062
13 Day Peru Splendors with Galapagos Cruise with Globus
Save Map View
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Nov 2024
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 165
From 10,181
32 Day Antarctica, Argentina & Brazil with Scenic
Save Map View
Tour + Cruise

32 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Departure: 28 February 2025
Countries Visited: Argentina, Antarctica, South Georgia Island, Falkland Islands (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$45,822
SUITE
$57,999
Save 13,463
From 45,822
12 Day Wonders of the Galápagos & Machu Picchu with Abercrombie & Kent
Save Map View
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departure: 03 November 2024
Countries Visited: Ecuador, Galapagos, Peru
From 26,490
15 Day Galapagos & Amazon (Archipel I) with Exodus Adventure Travels
Save Map View
Tour + Cruise

15 Days Quito to Guayaquil
Departures: Dec 2024 to Oct 2025
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 328
From 15,469
13 Day Highlights of Peru with Galápagos Legend North and Central Cruise with Trafalgar
Save Map View
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Sep 2024 to Nov 2024
Countries Visited: Peru, Ecuador
Exclusive Savings
From 12,301
19 Day Antarctica Adventure with Brazil with Travelmarvel
Save Map View
Tour + Cruise

19 Days Rio de Janeiro to Buenos Aires
Operated By: Travelmarvel
Departure: 04 November 2025
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Brazil, Argentina, Antarctica
Exclusive Deal
Save 1,920
From 18,475
13 Day Patagonia: Edge of the World with Collette
Save Map View
Tour + Cruise

13 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2024 to Mar 2025
Countries Visited: Argentina, Chile
Last Minute Deal
Save 409
From 10,169
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Save Map View
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2024 to Nov 2026
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 197
From 11,704
Results: 1-30 of 32

No Results found. Try changing your search filters.