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All South America Tour & Cruise Packages

Compare 61 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
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37 Days
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61 Packages (284 Package Departures)
11 Day Antarctica: The White Continent with Collette
Tour + Cruise

11 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Jan 2027 to Mar 2027
Visit: Chile, Argentina, Antarctica
Flash Sale
Exclusive Savings
From
US$10,449
Save 400
Per Person
View Trip
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
From
US$9,664
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departure: 21 February 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Inside
-
Oceanview
$13,795
Balcony
$15,085
Suite
-
From
US$13,795
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$10,482
Per Person
View Trip
24 Day Antarctic Voyage with Peru with APT
New ReleaseTour + Cruise

24 Days Lima to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 08 February 2028
Trip Styles: Cruise, Scenic
Visit: Peru, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$24,095
Suite
$25,995
From
US$24,095
Per Person
View Trip
31 Day Best of South America with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

31 Days Rio de Janeiro to Guayaquil
Operated By: APT
Departures: May 2027 to Oct 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
From
US$31,495
Per Person
View Trip
29 Day Best of South America with Amazon & Galápagos Cruises with APT
Tour + Cruise

29 Days Rio de Janeiro to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Feb 2028 to Sep 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
Inside
-
Oceanview
-
Balcony
-
Suite
$32,195
From
US$32,195
Per Person
View Trip
18 Day Land of the Incas with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

18 Days Lima to Quito
Operated By: Trafalgar
Departures: Oct 2026 to Dec 2026
Visit: Peru, Ecuador, Galapagos
Today's Deal
Exclusive Savings
From
US$9,361
Save 470
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2026 to Mar 2027
Visit: Argentina, Chile
Flash Sale
Exclusive Savings
From
US$9,799
Save 400
Per Person
View Trip
26 Day Best of South America with Galápagos Cruise with APT
New ReleaseTour + Cruise

26 Days Rio de Janeiro to Guayaquil
Operated By: APT
Departures: Apr 2027 to Nov 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
From
US$24,795
Per Person
View Trip
11 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Ecuador's Amazon with Globus
New ReleaseTour + Cruise

11 Days Quito to Guayaquil
Operated By: Globus
Departures: Jun 2026 to Dec 2026
Visit: Ecuador, Galapagos
From
US$7,559
Per Person
View Trip
20 Day Wonders of Patagonia & Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Nov 2028 to Nov 2028
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica, Chile
Inside
-
Oceanview
-
Balcony
$38,100
Suite
$41,745
From
US$38,100
Per Person
View Trip
13 Day Antarctica with Tauck
Tour + Cruise

13 Days Buenos Aires to Buenos Aires
Operated By: Tauck
Ship: Le Boréal
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica
From
US$14,490
Per Person
View Trip
21 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

21 Days Rio de Janeiro to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I, Scenic Ikon
Departures: Jan 2027 to Jan 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Brazil, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$31,930
Suite
$35,330
From
US$31,930
Per Person
View Trip
20 Day Antarctic Voyage with Brazil Highlights with APT
Tour + Cruise

20 Days Buenos Aires to Rio de Janeiro
Operated By: APT
Ships: Seabourn Venture
Departures: Feb 2027 to Feb 2028
Trip Styles: Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$21,995
Suite
$24,595
From
US$21,995
Per Person
View Trip
25 Day Vibrant Wonders of Peru & Beyond the Antarctic Circle - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

25 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 19 January 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Peru, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$37,190
Suite
$48,670
From
US$37,190
Per Person
View Trip
28 Day Patagonian Adventure with Antarctica, South Georgia - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

28 Days Buenos Aires to Santiago
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 10 January 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Falkland Islands, South Georgia Island, Antarctica, Chile
Inside
-
Oceanview
-
Balcony
$54,025
Suite
$68,785
From
US$54,025
Per Person
View Trip
29 Day Antarctic Voyage with South American Discovery with APT
Tour + Cruise

29 Days Lima to Rio de Janeiro
Operated By: APT
Ships: Seabourn Venture
Departures: Jan 2027 to Feb 2028
Trip Styles: Cruise, Scenic
Visit: Peru, Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$26,995
Suite
$29,595
From
US$26,995
Per Person
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ships: Seabourn Venture
Departures: Feb 2027 to Feb 2028
Trip Styles: Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$19,395
Suite
$21,995
From
US$19,395
Per Person
View Trip
17 Day Antarctica & Iguazu Falls Delight - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

17 Days Buenos Aires to Buenos Aires
Operated By: Scenic
Ship: Scenic Ikon
Departures: Jan 2029 to Feb 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$31,485
Suite
$34,730
From
US$31,485
Per Person
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Sep 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Sign Up Savings
Today's Deal
Exclusive Savings
From
US$11,220
Save 630
Per Person
View Trip
20 Day Spirit of Peru with Belmond Andean Explorer Train and Galápagos Cruise with APT
New ReleaseTour + Cruise

20 Days Lima to Guayaquil
Operated By: APT
Departures: May 2027 to Oct 2028
Visit: Peru, Ecuador, Galapagos
From
US$21,995
Per Person
View Trip
35 Day Antarctic Voyage with South American Discovery & Amazon Cruise with APT
New ReleaseTour + Cruise

35 Days Lima to Rio de Janeiro
Operated By: APT
Ships: Seabourn Venture, Delfin III
Departure: 25 January 2027
Trip Styles: Cruise, Wildlife, Scenic
Visit: Peru, Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$33,445
Suite
$36,045
From
US$33,445
Per Person
View Trip
22 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

22 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Mar 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$31,490
Suite
$36,460
From
US$31,490
Per Person
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departures: Jul 2026 to Sep 2026
Visit: Peru, Ecuador, Galapagos
From
US$11,410
Per Person
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Brazil
Inside
-
Oceanview
-
Balcony
$26,680
Suite
-
From
US$26,680
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departure: 09 November 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
From
US$12,635
Per Person
View Trip
30 Day Antarctic Voyage with Peru and Amazon Cruise with APT
New ReleaseTour + Cruise

30 Days Lima to Buenos Aires
Operated By: APT
Ships: Seabourn Venture, Delfin III
Departure: 25 January 2027
Trip Styles: Cruise, Wildlife, Scenic
Visit: Peru, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$28,495
Suite
$31,095
From
US$28,495
Per Person
View Trip
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$39,361
Suite
$44,597
From
US$39,361
Save 6,289
Per Person
View Trip
18 Day Spirit of Peru with Amazon and Galápagos Cruises with APT
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Feb 2028 to Sep 2028
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
-
Balcony
-
Suite
$22,195
From
US$22,195
Per Person
View Trip
Results: 1-30 of 61

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