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All South America Tour & Cruise Packages

Compare 61 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
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37 Days
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61 Packages (263 Package Departures)
11 Day Antarctica: The White Continent with Collette
Tour + Cruise

11 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Jan 2027 to Mar 2027
Visit: Chile, Argentina, Antarctica
Flash Sale
Exclusive Savings
From
US$10,449
Save 400
Per Person
View Trip
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
From
US$9,664
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Feb 2027 to Feb 2028
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Inside
-
Oceanview
$13,795
Balcony
$15,085
Suite
-
From
US$13,795
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$10,482
Per Person
View Trip
20 Day Antarctic Voyage with Brazil Highlights with APT
Tour + Cruise

20 Days Buenos Aires to Rio de Janeiro
Operated By: APT
Ships: Seabourn Venture
Departures: Feb 2027 to Feb 2028
Trip Styles: Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$21,995
Suite
$24,595
From
US$21,995
Per Person
View Trip
28 Day Patagonian Adventure with Antarctica, South Georgia - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

28 Days Buenos Aires to Santiago
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 10 January 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Falkland Islands, South Georgia Island, Antarctica, Chile
Inside
-
Oceanview
-
Balcony
$56,185
Suite
$68,785
From
US$56,185
Per Person
View Trip
23 Day Antarctic Voyage with Chile and Brazil Highlights with APT
New ReleaseTour + Cruise

23 Days Santiago to Rio de Janeiro
Operated By: APT
Ships: Seabourn Venture
Departures: Feb 2027 to Feb 2028
Trip Styles: Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$23,795
Suite
$26,395
From
US$23,795
Per Person
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Jan 2027 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
US$9,262
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2026 to Mar 2027
Visit: Argentina, Chile
Flash Sale
Exclusive Savings
From
US$9,799
Save 400
Per Person
View Trip
22 Day Vibrant Wonders of Peru & Antarctica - Cruise & Land Lourney with Scenic
New ReleaseTour + Cruise

22 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Ikon
Departures: Dec 2028 to Jan 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Peru, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$30,690
Suite
$33,935
From
US$30,690
Per Person
View Trip
13 Day Antarctica with Tauck
Tour + Cruise

13 Days Buenos Aires to Buenos Aires
Operated By: Tauck
Ship: Le Boréal
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica
From
US$14,490
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Quito
Operated By: Tauck
Ship: Silver Origin
Departures: Apr 2027 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
US$17,990
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$5,865
Save 1,033
Per Person
View Trip
29 Day Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Jan 2027 to Feb 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$45,985
Suite
$49,230
From
US$45,985
Per Person
View Trip
14 Day Voyaging Beyond the Antarctic Circle with Abercrombie & Kent
New ReleaseTour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Abercrombie & Kent
Departure: 06 January 2027
Trip Style: Cruise
Visit: Argentina, Antarctica
Inside
-
Oceanview
$18,595
Balcony
$19,595
Suite
$36,395
From
US$18,595
Per Person
View Trip
37 Day Machu Picchu, Amazon & Antarctic Odyssey - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

37 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse II
Departure: 26 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visit: Peru, Argentina, Falkland Islands, South Georgia Island, Antarctica
Inside
-
Oceanview
-
Balcony
$82,205
Suite
$104,255
From
US$82,205
Per Person
View Trip
15 Day Spirit of Peru with Galápagos Cruise with APT
New ReleaseTour + Cruise

15 Days Lima to Guayaquil
Operated By: APT
Departures: May 2027 to Nov 2028
Visit: Peru, Ecuador, Galapagos
From
US$15,395
Per Person
View Trip
29 Day Southern Expedition: Antarctica & Machu Picchu - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Lima to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I
Departures: Nov 2028 to Feb 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Peru, Argentina, Falkland Islands, South Georgia Island, Antarctica
Inside
-
Oceanview
-
Balcony
$43,290
Suite
$58,050
From
US$43,290
Per Person
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ships: Seabourn Venture
Departures: Feb 2027 to Feb 2028
Trip Styles: Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$19,395
Suite
$21,995
From
US$19,395
Per Person
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
From
US$7,376
Per Person
View Trip
22 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

22 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Mar 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$31,545
Suite
$36,460
From
US$31,545
Per Person
View Trip
30 Day Antarctic Voyage with Peru and Amazon Cruise with APT
New ReleaseTour + Cruise

30 Days Lima to Buenos Aires
Operated By: APT
Ships: Seabourn Venture, Delfin III
Departure: 25 January 2027
Trip Styles: Cruise, Wildlife, Scenic
Visit: Peru, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$28,495
Suite
$31,095
From
US$28,495
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$39,185
Suite
$47,435
From
US$39,185
Per Person
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departure: 22 September 2026
Visit: Peru, Ecuador, Galapagos
From
US$11,410
Per Person
View Trip
19 Day Antarctica, South Georgia & Falklands: Holiday Voyage with Abercrombie & Kent
Tour + Cruise

19 Days Buenos Aires to Buenos Aires
Operated By: Abercrombie & Kent
Departure: 20 December 2026
Trip Styles: Cruise, Festive
Visit: Argentina, Falkland Islands, South Georgia Island, Antarctica
Inside
-
Oceanview
-
Balcony
$25,995
Suite
$37,995
From
US$25,995
Per Person
View Trip
28 Day Antarctica, South Georgia, Argentina & Brazil - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

28 Days Rio de Janeiro to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I
Departures: Nov 2028 to Jan 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Brazil, Argentina, Falkland Islands, South Georgia Island, Antarctica
Inside
-
Oceanview
-
Balcony
$44,665
Suite
$59,425
From
US$44,665
Per Person
View Trip
18 Day Spirit of Peru with Amazon and Galápagos Cruises with APT
New ReleaseTour + Cruise

18 Days Lima to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Feb 2028 to Sep 2028
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
-
Balcony
-
Suite
$22,195
From
US$22,195
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
From
US$8,635
Per Person
View Trip
17 Day Antarctica & Iguazu Falls Delight - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

17 Days Buenos Aires to Buenos Aires
Operated By: Scenic
Ship: Scenic Ikon
Departures: Jan 2029 to Feb 2029
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$31,485
Suite
$34,730
From
US$31,485
Per Person
View Trip
14 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

14 Days Lima to Quito
Operated By: Collette
Departures: Aug 2026 to May 2027
Visit: Peru, Ecuador, Galapagos
Flash Sale
Exclusive Savings
From
US$9,799
Save 400
Per Person
View Trip
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