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All South America Tour & Cruise Packages

Compare 43 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
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43 Packages (282 Package Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Oct 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$9,416
Save 344
Per Person
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departure: 21 February 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Falkland Islands, Uruguay, Brazil, Peru
Exclusive Savings
Inside
-
Oceanview
$13,572
Balcony
$14,836
Suite
-
From
US$13,572
Save 223
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Jul 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Black Friday Sale
Exclusive Savings
From
US$9,872
Save 540
Per Person
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visit: Peru, Chile, Argentina
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$27,449
Suite
-
From
US$27,449
Save 23,306
Per Person
View Trip
13 Day Antarctica with Tauck
Tour + Cruise

13 Days Buenos Aires to Buenos Aires
Operated By: Tauck
Ship: Le Boréal
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica
From
US$14,490
Per Person
View Trip
14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Mar 2026 to Mar 2027
Visit: Argentina, Chile
Exclusive Savings
From
US$10,010
Save 889
Per Person
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Aug 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$11,454
Save 396
Per Person
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operated By: Globus
Departures: Nov 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$13,862
Save 502
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Mar 2026 to Dec 2027
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$5,354
Save 1,544
Per Person
View Trip
20 Day Antarctic Voyage with Brazil Highlights with APT
Tour + Cruise

20 Days Buenos Aires to Rio de Janeiro
Operated By: APT
Ship: Seabourn Venture
Departure: 09 February 2027
Trip Styles: Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,601
Suite
$24,149
From
US$21,601
Save 394
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Sep 2026 to Nov 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$8,369
Save 298
Per Person
View Trip
23 Day Antarctic Voyage with Chile and Brazil Highlights with APT
New ReleaseTour + Cruise

23 Days Santiago to Rio de Janeiro
Operated By: APT
Ship: Seabourn Venture
Departure: 06 February 2027
Trip Styles: Cruise, Scenic
Visit: Chile, Argentina, Antarctica, Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$23,373
Suite
$25,921
From
US$23,373
Save 422
Per Person
View Trip
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Fly Free Business Class
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$42,053
Suite
$48,029
From
US$42,053
Save 26,882
Per Person
View Trip
9 Day Cruising the Galapagos Islands with Tauck
Tour + Cruise

9 Days Guayaquil to Guayaquil
Operated By: Tauck
Departures: Jul 2026 to Dec 2027
Visit: Ecuador, Galapagos
From
US$9,190
Per Person
View Trip
14 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

14 Days Lima to Quito
Operated By: Collette
Departures: Apr 2026 to May 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$9,735
Save 170
Per Person
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Brazil
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$23,044
Suite
-
From
US$23,044
Save 22,711
Per Person
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 06 February 2027
Trip Styles: Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,045
Suite
$21,593
From
US$19,045
Save 350
Per Person
View Trip
22 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

22 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Feb 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Antarctica, Brazil
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$25,986
Suite
$29,163
From
US$25,986
Save 25,719
Per Person
View Trip
17 Day Mysteries of the Inca Empire with Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2026 to Nov 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$6,775
Save 461
Per Person
View Trip
21 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

21 Days Rio de Janeiro to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Jan 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Brazil, Argentina, Antarctica
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$26,680
Suite
$29,590
From
US$26,680
Save 26,015
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$8,729
Save 287
Per Person
View Trip
11 Day Antarctica: The White Continent with Collette
Tour + Cruise

11 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Nov 2026 to Mar 2027
Visit: Chile, Argentina, Antarctica
Exclusive Savings
From
US$10,269
Save 200
Per Person
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Mar 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
US$14,690
Per Person
View Trip
35 Day Antarctic Voyage with South American Discovery & Amazon Cruise with APT
New ReleaseTour + Cruise

35 Days Lima to Rio de Janeiro
Operated By: APT
Ships: Seabourn Venture, Delfin III
Departure: 25 January 2027
Trip Styles: Cruise, Wildlife, Scenic
Visit: Peru, Argentina, Antarctica, Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$32,864
Suite
$35,412
From
US$32,864
Save 581
Per Person
View Trip
24 Day Antarctic Voyage with Peru with APT
New ReleaseTour + Cruise

24 Days Lima to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 31 January 2027
Trip Styles: Cruise, Scenic
Visit: Peru, Argentina, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$22,297
Suite
$24,845
From
US$22,297
Save 398
Per Person
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Tour + Cruise

8 Days Quito to Guayaquil
Operated By: Tauck
Departures: Jul 2026 to Dec 2026
Visit: Ecuador, Galapagos
From
US$6,690
Per Person
View Trip
18 Day Land of the Incas with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

18 Days Lima to Quito
Operated By: Trafalgar
Departures: Jul 2026 to Nov 2026
Visit: Peru, Ecuador
Sign Up Savings
Exclusive Savings
From
US$9,499
Save 332
Per Person
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departures: Jun 2026 to Sep 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$11,035
Save 386
Per Person
View Trip
23 Day Legacy of the Incas with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

23 Days Lima to Guayaquil
Operated By: Globus
Departure: 29 May 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$12,557
Save 422
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse II, Scenic Eclipse I
Departures: Jan 2027 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$38,983
Suite
$39,735
From
US$38,983
Save 23,622
Per Person
View Trip
Results: 1-30 of 43

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