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All Mekong River Cruises

Experience iconic temples, palaces and pagodas, colourful markets, the ancient culture, history and diverse local foods amongst the fascinating places you'll visit along the mighty Mekong River onboard your luxurious river cruise. Choose from 906 river cruises along the Mekong traveling with the world's leading river cruise lines.
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61 River Cruises (906 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,385
From
US$5,385
Save 3,247
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$6,556
Suite
$8,574
From
US$6,556
Save 1,512
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,233
Balcony
$4,900
Suite
$6,940
From
US$4,233
Save 402
Per Person
View Trip
24 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$11,855
Suite
$14,601
From
US$11,855
Save 918
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$11,855
Suite
$14,601
From
US$11,855
Save 848
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
24 Day Grand Tour of Indochina with Emerald Cruises
River Cruise
 (6)

24 Days Hanoi to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$8,924
Balcony
$9,381
Suite
$11,495
From
US$8,924
Save 451
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$6,823
Balcony
$6,962
Suite
$9,394
From
US$6,823
Save 412
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 800
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 1,000
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$2,914
Balcony
$3,517
Suite
$5,620
From
US$2,914
Save 359
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$4,233
Balcony
$4,713
Suite
$6,940
From
US$4,233
Save 363
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$5,480
Balcony
$5,960
Suite
$8,186
From
US$5,480
Save 395
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$6,454
Balcony
$6,911
Suite
$9,394
From
US$6,454
Save 412
Per Person
View Trip
18 Day Highlights of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: May 2026 to Oct 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$8,904
Suite
$11,489
From
US$8,904
Save 746
Per Person
View Trip
20 Day Highlights of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

20 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$10,658
Suite
$13,404
From
US$10,658
Save 934
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$3,203
Balcony
$3,660
Suite
$5,774
From
US$3,203
Save 286
Per Person
View Trip
18 Day Journey along the Mekong with Scenic
River Cruise

18 Days Ho Chi Minh City to Bangkok
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$9,517
Suite
$13,236
From
US$9,517
Save 679
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$5,869
Suite
$8,574
From
US$5,869
Save 611
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound) with Avalon River Cruises
River Cruise

16 Days Siem Reap to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,276
From
US$6,276
Save 2,277
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Southbound) with Avalon River Cruises
River Cruise

16 Days Hanoi to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,593
From
US$6,593
Save 2,290
Per Person
View Trip
23 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

23 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$6,826
Balcony
$7,283
Suite
$9,397
From
US$6,826
Save 378
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$1,959
Suite
$3,704
From
US$1,959
Save 1,328
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$7,623
Suite
$10,369
From
US$7,623
Save 799
Per Person
View Trip
26 Day Wonders of Japan, Vietnam and Cambodia with Emerald Cruises
New ReleaseRiver Cruise
 (6)

26 Days Osaka to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to Apr 2027
Rivers: Mekong
Visit: Japan, Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$14,313
Balcony
$14,769
Suite
$16,884
From
US$14,313
Save 689
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

19 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Select Fare
Preferred Plus Fare + Reduced Air Offer
Exclusive Savings
Inside
-
River View
$5,919
Balcony
$6,375
Suite
$8,490
From
US$5,919
Save 360
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

19 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Preferred Plus Fare + Reduced Air Offer
Select Fare
Exclusive Savings
Inside
-
River View
$5,919
Balcony
$6,375
Suite
$8,490
From
US$5,919
Save 360
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Mar 2026 to May 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
$2,914
Balcony
$3,394
Suite
$5,620
From
US$2,914
Save 111
Per Person
View Trip
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