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All Mekong River Cruises

Experience iconic temples, palaces and pagodas, colourful markets, the ancient culture, history and diverse local foods amongst the fascinating places you'll visit along the mighty Mekong River onboard your luxurious river cruise. Choose from 1,046 river cruises along the Mekong traveling with the world's leading river cruise lines.
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67 River Cruises (1,046 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Feb 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ship: Mekong Jewel
Departures: Mar 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,385
From
US$5,385
Save 2,614
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,295
Suite
$8,162
From
US$6,295
Save 11,268
Per Person
View Trip
24 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$10,602
Suite
$13,492
From
US$10,602
Save 10,183
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$11,111
Suite
$13,492
From
US$11,111
Save 10,469
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$8,490
Balcony
$8,975
Suite
$11,206
From
US$8,490
Save 6,258
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Feb 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 2,500
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Jan 2026 to Dec 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$10,999
From
US$6,499
Save 2,000
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$4,563
Balcony
$3,617
Suite
$7,328
From
US$3,617
Save 7,023
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$4,039
Balcony
$4,524
Suite
$6,755
From
US$4,039
Save 7,270
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$5,882
Balcony
$4,937
Suite
$8,710
From
US$4,937
Save 7,063
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

17 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$7,187
Balcony
$7,812
Suite
$10,043
From
US$7,187
Save 6,498
Per Person
View Trip
10 Day Riches of the Mekong with Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

10 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Mar 2026 to Apr 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$3,800
Suite
$5,335
From
US$3,800
Save 172
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseRiver Cruise
 (4)

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Feb 2026 to Feb 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
$11,348
Balcony
-
Suite
-
From
US$11,348
Save 342
Per Person
View Trip
13 Day Riches of the Mekong with Siem Reap and Ho Chi Minh City with AmaWaterways
New ReleaseRiver Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ship: AmaDara
Departures: Mar 2026 to Apr 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$4,567
Suite
$6,102
From
US$4,567
Save 204
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

19 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Wave Offer
Exclusive Savings
Inside
-
River View
$6,116
Balcony
$6,601
Suite
$8,832
From
US$6,116
Save 7,379
Per Person
View Trip
24 Day Grand Tour of Indochina with Emerald Cruises
River Cruise
 (4)

24 Days Hanoi to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Fly Free Economy
Exclusive Savings
Inside
-
River View
$10,591
Balcony
$11,076
Suite
$13,307
From
US$10,591
Save 6,296
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Wave Offer
Exclusive Savings
Inside
-
River View
$3,401
Balcony
$4,225
Suite
$6,117
From
US$3,401
Save 7,665
Per Person
View Trip
22 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$11,340
Suite
$13,457
From
US$11,340
Save 11,808
Per Person
View Trip
26 Day Wonders of Japan, Vietnam and Cambodia with Emerald Cruises
New ReleaseRiver Cruise
 (4)

26 Days Osaka to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to Apr 2027
Rivers: Mekong
Visit: Japan, Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$15,980
Balcony
$16,465
Suite
$18,696
From
US$15,980
Save 6,502
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

21 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$8,005
Balcony
$8,490
Suite
$10,721
From
US$8,005
Save 6,258
Per Person
View Trip
23 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

23 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$6,794
Balcony
$7,279
Suite
$9,510
From
US$6,794
Save 7,396
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

19 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$8,250
Balcony
$6,601
Suite
$8,832
From
US$6,601
Save 7,379
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$4,783
Balcony
$5,268
Suite
$7,499
From
US$4,783
Save 7,708
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$4,730
Suite
$7,620
From
US$4,730
Save 10,064
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
New ReleaseRiver Cruise
 (4)

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Fly Free Economy
Exclusive Savings
Inside
-
River View
$8,580
Balcony
$9,065
Suite
$11,296
From
US$8,580
Save 6,247
Per Person
View Trip
27 Day Grand Indochina & Luxury Mekong with Scenic
River Cruise

27 Days Hanoi to Bangkok
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Wave Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$14,728
Suite
$17,619
From
US$14,728
Save 9,728
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Wave Offer
Exclusive Savings
Inside
-
River View
$3,740
Balcony
$3,886
Suite
$6,117
From
US$3,740
Save 7,304
Per Person
View Trip
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