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Mekong River Cruises Starting In September 2026, 2027 and 2028

Are you planning a river cruise along the Mekong in September 2026, 2027 or 2028? Choose from 45 unique river cruises with 821 departures operated by Mekong's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the Mekong river cruise that best matches your travel style, budget and dates.
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45 River Cruises (821 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,385
From
US$5,385
Save 2,937
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$6,586
Suite
$8,962
From
US$6,586
Save 10,681
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,024
Balcony
$5,106
Suite
$7,337
From
US$5,024
Save 7,179
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$12,372
Suite
$14,292
From
US$12,372
Save 9,094
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
24 Day Grand Tour of Indochina with Emerald Cruises
River Cruise
 (6)

24 Days Hanoi to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Early Payment Discount
Exclusive Savings
Inside
-
River View
$9,621
Balcony
$10,106
Suite
$12,337
From
US$10,106
Save 7,266
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Apr 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,520
Balcony
$7,316
Suite
$10,236
From
US$7,520
Save 7,228
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,999
Suite
$10,999
From
US$6,999
Save 4,500
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Mar 2026 to Dec 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,999
Suite
$10,999
From
US$6,999
Save 4,500
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,621
Balcony
$5,106
Suite
$7,337
From
US$5,024
Save 7,179
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
River Cruise
 (6)

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Early Payment Discount
Exclusive Savings
Inside
-
River View
$7,610
Balcony
$8,095
Suite
$10,326
From
US$7,853
Save 7,217
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$7,009
Suite
$8,420
From
US$7,009
Save 11,324
Per Person
View Trip
22 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$10,867
Suite
$13,757
From
US$10,867
Save 10,434
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$5,365
Balcony
$5,850
Suite
$8,081
From
US$5,365
Save 6,868
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,926
Balcony
$6,411
Suite
$8,642
From
US$6,357
Save 7,210
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$7,649
Suite
$9,061
From
US$7,649
Save 11,344
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,032
From
US$5,032
Save 2,242
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$3,983
Balcony
$4,468
Suite
$6,699
From
US$3,983
Save 6,722
Per Person
View Trip
19 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok (Northbound) with Avalon River Cruises
River Cruise

19 Days Hanoi to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$7,746
From
US$7,746
Save 2,327
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$5,365
Balcony
$5,850
Suite
$8,081
From
US$5,365
Save 6,868
Per Person
View Trip
22 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$10,566
Suite
$14,242
From
US$12,079
Save 12,830
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$2,151
Suite
$3,782
From
US$2,151
Save 1,344
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Northbound) with Avalon River Cruises
River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,363
From
US$6,363
Save 2,280
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ships: Scenic Spirit
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$5,931
Suite
$8,322
From
US$5,931
Save 10,661
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$2,055
Suite
$3,704
From
US$2,055
Save 1,348
Per Person
View Trip
23 Day Indochina Mekong Journey with Emerald Cruises
River Cruise
 (6)

23 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Oct 2027
Rivers: Mekong
Visit: Vietnam, Laos, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$8,550
Balcony
$9,035
Suite
$12,356
From
US$9,155
Save 7,282
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

19 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,698
Balcony
$7,183
Suite
$9,414
From
US$6,698
Save 6,282
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound) with Avalon River Cruises
River Cruise

16 Days Siem Reap to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Mar 2026 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,276
From
US$6,276
Save 2,277
Per Person
View Trip
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