Home > All River Cruises > Asia River Cruises > Mekong River Cruises > September

Mekong River Cruises Starting In September 2027 and 2028

Are you planning a river cruise along the Mekong in September 2027 or 2028? Choose from 62 unique river cruises with 989 departures operated by Mekong's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the Mekong river cruise that best matches your travel style, budget and dates.
Filter Results
62 River Cruises (989 Departures)
62 River Cruises (989 Departures)
Departures
Duration
8 Days
27 Days
Types
Start & End Cities
Cruise Lines
Show More...
Price
$2,000pp
$54,135pp
Countries
15 Day Magnificent Mekong with Viking River Cruises Featured
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Mar 2027 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$13,323
Suite
$21,849
From (Per Person)
A$13,323
Save 380
Per Person
View Trip
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,872
Suite
$8,828
From (Per Person)
A$6,872
Save 2,335
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,065
Suite
$5,098
From (Per Person)
A$3,143
Save 3,030
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$3,143
Suite
$5,098
From (Per Person)
A$3,143
Save 780
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Mar 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,461
Suite
$9,318
From (Per Person)
A$8,147
Save 3,334
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$3,831
Suite
$6,669
From (Per Person)
A$4,713
Save 3,064
Per Person
View Trip
20 Day Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (10)

20 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Jul 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,756
Suite
$9,711
From (Per Person)
A$7,756
Save 1,661
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,363
Suite
$9,808
From (Per Person)
A$7,853
Save 3,632
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$4,125
Suite
$6,375
From (Per Person)
A$4,419
Save 3,070
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,953
Suite
$14,712
From (Per Person)
A$12,953
Save 2,378
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$15,013
Suite
$16,380
From (Per Person)
A$15,013
Save 2,410
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,561
Suite
$14,516
From (Per Person)
A$13,247
Save 3,736
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,795
Suite
$12,260
From (Per Person)
A$10,795
Save 2,630
Per Person
View Trip
16 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (2)

16 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Mar 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,676
Suite
$8,631
From (Per Person)
A$6,676
Save 1,641
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Avalon
Ships: Avalon Saigon
Departures: Oct 2026 to Nov 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Avalon
Ships: Avalon Saigon
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,417
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Operator: Uniworld
Ships: Mekong Jewel
Departures: Nov 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$9,170
From (Per Person)
A$9,170
Save 2,676
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Nov 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,015
Suite
$11,725
From (Per Person)
A$10,015
Save 2,730
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Feb 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,501
Suite
$12,064
From (Per Person)
A$11,089
Save 2,906
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,727
Suite
$9,775
From (Per Person)
A$7,354
Save 1,641
Per Person
View Trip
13 Day A Mekong Experience with Wendy Wu Tours
New ReleaseTour + River CruiseFlights Included
 (1)

13 Days Ho Chi Minh City to Siem Reap
Operator: Wendy Wu
Departures: Sep 2027 to Oct 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
From (Per Person)
A$7,634
Save 676
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
Tour + River Cruise
 (1)

24 Days Hanoi to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Sep 2027 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$17,081
Suite
$20,001
From (Per Person)
A$17,081
Save 3,347
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operator: Avalon
Ships: Avalon Saigon
Departures: Oct 2026 to Nov 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
24 Day Grand Tour of Indochina with Emerald Cruises
Tour + River Cruise
 (7)

24 Days Hanoi to Bangkok
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
River View
$13,990
Balcony
$14,852
Suite
$17,465
From (Per Person)
A$14,398
Save 1,240
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$10,502
Balcony
$11,394
Suite
$13,570
From (Per Person)
A$10,502
Save 1,201
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Nov 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,539
Suite
$21,849
From (Per Person)
A$12,539
Save 2,760
Per Person
View Trip
23 Day Natural Wonders of Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (1)

23 Days Hanoi to Siem Reap
Operator: Travelmarvel
Ship: RV Lotus
Departures: Jul 2027 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,738
Suite
$10,693
From (Per Person)
A$8,738
Save 1,687
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

15 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ship: Emerald Harmony
Departures: Jul 2027 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$7,602
Balcony
$8,493
Suite
-
From (Per Person)
A$7,602
Save 171
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,340
Balcony
$6,531
Suite
$9,775
From (Per Person)
A$7,354
Save 1,641
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

16 Days Ho Chi Minh City to Bangkok
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
River View
$9,945
Balcony
$11,004
Suite
$14,317
From (Per Person)
A$11,249
Save 1,208
Per Person
View Trip
Results: 1-29 of 62

No trips found. Try adjusting the search filters.




River Cruises found! Scroll up to view.

Asia River Cruises

Asia River Cruises India (Ganges) River Cruises Mekong River Cruises Yangtze River Cruises

Countries

Cambodia Thailand Vietnam

Cities

River Cruises from Hanoi River Cruises from Ho Chi Minh City River Cruises from Siem Reap

Routes

River Cruises from Hanoi to Siem Reap River Cruises from Hanoi to Ho Chi Minh City River Cruises from Ho Chi Minh City to Siem Reap River Cruises from Siem Reap to Ho Chi Minh City
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations