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Mekong River Cruises Starting In October 2026, 2027 and 2028

Are you planning a river cruise along the Mekong in October 2026, 2027 or 2028? Choose from 69 unique river cruises with 1,417 departures operated by Mekong's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the Mekong river cruise that best matches your travel style, budget and dates.
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69 River Cruises (1,417 River Cruise Departures)
13 Day Vietnam and Cambodia Highlights with APT
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Half Price Cabin Upgrade
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$5,697
Suite
$7,652
From
A$5,697
Save 3,804
Per Person
View Trip
17 Day Discover Vietnam and Cambodia with Travelmarvel
River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$6,676
Suite
$8,338
From
A$6,676
Save 2,326
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Jul 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$2,457
Suite
$4,412
From
A$2,457
Save 1,538
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Jul 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$3,733
Suite
$5,689
From
A$3,733
Save 2,378
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$2,849
Suite
$4,412
From
A$2,849
Save 1,552
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$5,305
Suite
$7,260
From
A$5,305
Save 4,190
Per Person
View Trip
20 Day Wonders of Vietnam and Cambodia with Travelmarvel
River Cruise
 (10)

20 Days Hanoi to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Mar 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$6,874
Suite
$8,829
From
A$6,874
Save 2,821
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$4,027
Suite
$5,689
From
A$4,027
Save 2,375
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$10,209
Suite
$12,164
From
A$10,209
Save 4,286
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
River Cruise
 (5)

25 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$12,367
Suite
$14,322
From
A$12,367
Save 4,328
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$10,699
Suite
$12,654
From
A$10,699
Save 4,296
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
River Cruise
 (3)

17 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$8,443
Suite
$10,398
From
A$8,443
Save 4,052
Per Person
View Trip
16 Day Discover Vietnam and Cambodia with Travelmarvel
River Cruise
 (2)

16 Days Hanoi to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Mar 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$5,990
Suite
$7,945
From
A$5,990
Save 2,305
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,043
From
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,043
From
A$5,043
Save 3,405
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
The 50th Anniversary Sale
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$8,650
From
A$8,513
Save 4,247
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Pay In Full Offer
Exclusive Savings
Inside
-
River View
-
Balcony
$8,893
Suite
$11,725
From
A$8,893
Save 2,704
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$8,541
Suite
$10,496
From
A$8,541
Save 4,060
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
$5,668
Balcony
$6,531
Suite
$8,643
From
A$5,668
Save 1,652
Per Person
View Trip
13 Day A Mekong Experience with Wendy Wu Tours
New ReleaseRiver Cruise
 (1)

13 Days Ho Chi Minh City to Siem Reap
Operated By: Wendy Wu Tours
Departures: Sep 2026 to Oct 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
From
A$7,722
Save 678
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$10,131
From
A$10,131
Save 3,541
Per Person
View Trip
24 Day Grand Tour of Indochina with Emerald Cruises
River Cruise
 (6)

24 Days Hanoi to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Multiple Deals Available
Inside
-
River View
$12,928
Balcony
$13,818
Suite
$15,960
From
A$12,928
Save 1,738
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
$9,032
Balcony
$9,924
Suite
$12,100
From
A$9,032
Save 1,698
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Viking Savings Event
Exclusive Savings
Inside
-
River View
-
Balcony
$7,247
Suite
$12,441
From
A$7,247
Save 8,064
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Viking Savings Event
Exclusive Savings
Inside
-
River View
-
Balcony
$7,247
Suite
$14,597
From
A$7,247
Save 7,494
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
$4,517
Balcony
$5,379
Suite
$7,491
From
A$4,517
Save 622
Per Person
View Trip
23 Day Natural Wonders of Vietnam and Cambodia with Travelmarvel
River Cruise
 (1)

23 Days Hanoi to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Mar 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$7,856
Suite
$9,811
From
A$7,856
Save 2,839
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
$5,884
Balcony
$6,531
Suite
$8,951
From
A$5,884
Save 1,646
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (6)

17 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
$7,951
Balcony
$8,843
Suite
$11,018
From
A$7,951
Save 1,679
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
River Cruise
 (6)

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visit: Vietnam, Cambodia, Laos, Thailand
Multiple Deals Available
Inside
-
River View
$9,779
Balcony
$10,671
Suite
$12,847
From
A$9,779
Save 1,687
Per Person
View Trip
Results: 1-29 of 69

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