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Mekong River Cruises Starting In April 2027 and 2028

Are you planning a river cruise along the Mekong in April 2027 or 2028? Choose from 56 unique river cruises with 1,090 departures operated by Mekong's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the Mekong river cruise that best matches your travel style, budget and dates.
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56 River Cruises (1,090 Departures)
56 River Cruises (1,090 Departures)
Departures
Duration
8 Days
41 Days
Types
Start & End Cities
Cruise Lines
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Price
$2,400pp
$51,245pp
Countries
12 Day Essential Vietnam and Cambodia with Travelmarvel Featured
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$3,733
Suite
$5,689
From (Per Person)
A$4,223
Save 2,362
Per Person
View Trip
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,676
Suite
$8,632
From (Per Person)
A$6,676
Save 2,041
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Jul 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$2,457
Suite
$4,412
From (Per Person)
A$2,947
Save 1,538
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$3,733
Suite
$5,689
From (Per Person)
A$4,223
Save 2,391
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: Travelmarvel
Ships: RV Lotus
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,457
Suite
$4,412
From (Per Person)
A$2,947
Save 1,538
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$5,305
Suite
$7,260
From (Per Person)
A$5,305
Save 4,190
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$10,993
Suite
$12,948
From (Per Person)
A$10,993
Save 3,806
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$13,053
Suite
$15,008
From (Per Person)
A$13,739
Save 3,842
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$5,697
Suite
$7,652
From (Per Person)
A$5,697
Save 3,804
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$11,679
Suite
$13,634
From (Per Person)
A$11,679
Save 3,824
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$9,227
Suite
$11,182
From (Per Person)
A$9,227
Save 3,574
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld
Ships: Mekong Jewel
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$9,267
From (Per Person)
A$12,159
Save 741
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,893
Suite
$11,725
From (Per Person)
A$8,893
Save 2,704
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,835
Suite
$10,790
From (Per Person)
A$8,835
Save 4,060
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,531
Suite
$8,643
From (Per Person)
A$5,668
Save 1,646
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon
Ship: Avalon Saigon
Departures: Aug 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
24 Day Grand Tour of Indochina with Emerald Cruises
Tour + River Cruise
 (6)

24 Days Hanoi to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
River View
$12,928
Balcony
$13,820
Suite
$15,960
From (Per Person)
A$12,928
Save 1,738
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,032
Balcony
$9,924
Suite
$12,100
From (Per Person)
A$9,032
Save 1,698
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking
Ship: Viking Saigon
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,247
Suite
$12,441
From (Per Person)
A$7,247
Save 8,064
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking
Ship: Viking Saigon
Departures: Aug 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$8,031
Suite
$16,851
From (Per Person)
A$8,031
Save 8,064
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,517
Balcony
$5,379
Suite
$7,491
From (Per Person)
A$4,517
Save 622
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$5,884
Balcony
$6,531
Suite
$8,951
From (Per Person)
A$5,884
Save 1,646
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (6)

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,938
Balcony
$6,800
Suite
$8,912
From (Per Person)
A$5,938
Save 651
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (6)

17 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$7,951
Balcony
$8,843
Suite
$11,018
From (Per Person)
A$7,951
Save 1,679
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
Tour + River Cruise
 (6)

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
River View
$9,779
Balcony
$10,671
Suite
$12,847
From (Per Person)
A$9,779
Save 1,687
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (6)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$4,659
Balcony
$5,379
Suite
$7,726
From (Per Person)
A$4,659
Save 622
Per Person
View Trip
23 Day Indochina Mekong Journey with Emerald Cruises
Tour + River Cruise
 (6)

23 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Nov 2026 to Mar 2028
Rivers: Mekong
Visits: Vietnam, Laos, Cambodia
Exclusive Savings
River View
$13,094
Balcony
$13,957
Suite
$16,529
From (Per Person)
A$13,094
Save 1,756
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (6)

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,129
Balcony
$6,800
Suite
$9,196
From (Per Person)
A$6,129
Save 651
Per Person
View Trip
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