Home > All River Cruises > Asia River Cruises > Mekong River Cruises > April

Mekong River Cruises Starting In April 2027 and 2028

Are you planning a river cruise along the Mekong in April 2027 or 2028? Choose from 59 unique river cruises with 1,087 departures operated by Mekong's leading river cruise lines. Easily compare prices, itineraries, inclusions and traveller reviews to find the Mekong river cruise that best matches your travel style, budget and dates.
Filter Results
59 River Cruises (1,087 Departures)
59 River Cruises (1,087 Departures)
Departures
Duration
8 Days
41 Days
Types
Start & End Cities
Cruise Lines
Show More...
Price
$2,200pp
$53,025pp
Countries
15 Day Magnificent Mekong with Viking River Cruises Featured
Tour + River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Oct 2026 to Dec 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,031
Suite
$21,849
From (Per Person)
A$8,031
Save 7,464
Per Person
View Trip
17 Day Discover Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (5)

17 Days Hanoi to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Jan 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$6,676
Suite
$8,632
From (Per Person)
A$6,676
Save 3,046
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (8)

8 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$2,457
Suite
$4,412
From (Per Person)
A$2,947
Save 2,364
Per Person
View Trip
8 Day Majestic Mekong Cruise with Travelmarvel
River Cruise
 (1)

8 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$2,261
Suite
$4,020
From (Per Person)
A$2,947
Save 3,056
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (16)

12 Days Ho Chi Minh City to Siem Reap
Operator: Travelmarvel
Ships: RV Lotus
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$4,223
Suite
$5,787
From (Per Person)
A$4,223
Save 3,089
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$7,363
Suite
$9,318
From (Per Person)
A$7,363
Save 3,632
Per Person
View Trip
12 Day Essential Vietnam and Cambodia with Travelmarvel
Tour + River Cruise
 (7)

12 Days Siem Reap to Ho Chi Minh City
Operator: Travelmarvel
Ships: RV Lotus
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$3,929
Suite
$5,591
From (Per Person)
A$4,223
Save 3,585
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$11,973
Suite
$13,928
From (Per Person)
A$11,973
Save 3,722
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$13,837
Suite
$15,792
From (Per Person)
A$14,131
Save 3,764
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$7,069
Suite
$9,024
From (Per Person)
A$7,069
Save 3,040
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$12,561
Suite
$14,516
From (Per Person)
A$12,561
Save 3,252
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operator: APT
Ships: Mekong Serenity
Departures: Nov 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$9,717
Suite
$11,672
From (Per Person)
A$9,717
Save 4,118
Per Person
View Trip
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Avalon
Ship: Avalon Saigon
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,405
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operator: Avalon
Ship: Avalon Saigon
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Suite
$5,043
From (Per Person)
A$5,043
Save 3,417
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
Tour + River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Operator: Uniworld
Ships: Mekong Jewel
Departures: Nov 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,199
From (Per Person)
A$10,199
Save 2,701
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
Tour + River Cruise
 (2)

13 Days Ho Chi Minh City to Siem Reap
Operator: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to Dec 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$8,893
Suite
$11,725
From (Per Person)
A$8,893
Save 2,732
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operator: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Balcony
$9,913
Suite
$11,672
From (Per Person)
A$9,913
Save 4,088
Per Person
View Trip
13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,668
Balcony
$6,727
Suite
$8,951
From (Per Person)
A$5,668
Save 1,664
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
Tour + River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operator: Avalon
Ship: Avalon Saigon
Departures: Sep 2026 to Nov 2027
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Suite
$10,131
From (Per Person)
A$10,131
Save 3,541
Per Person
View Trip
24 Day Grand Tour of Indochina with Emerald Cruises
Tour + River Cruise
 (7)

24 Days Hanoi to Bangkok
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2027 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
River View
$12,928
Balcony
$13,820
Suite
$15,995
From (Per Person)
A$12,928
Save 1,738
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Feb 2027 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,032
Balcony
$9,924
Suite
$12,100
From (Per Person)
A$9,032
Save 1,716
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
Tour + River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Operator: Viking
Ships: Viking Saigon, Viking Tonle
Departures: Sep 2026 to Dec 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Balcony
$8,031
Suite
$21,849
From (Per Person)
A$8,031
Save 7,464
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (7)

8 Days Ho Chi Minh City to Phnom Penh
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$4,517
Balcony
$5,551
Suite
$7,726
From (Per Person)
A$4,517
Save 640
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

13 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$5,884
Balcony
$6,531
Suite
$8,951
From (Per Person)
A$5,884
Save 1,646
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Siem Reap to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
River View
$6,129
Balcony
$6,800
Suite
$9,196
From (Per Person)
A$6,129
Save 651
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

17 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$7,951
Balcony
$8,843
Suite
$11,018
From (Per Person)
A$8,446
Save 1,679
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

17 Days Hanoi to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$7,951
Balcony
$8,843
Suite
$11,018
From (Per Person)
A$7,951
Save 1,679
Per Person
View Trip
11 Day Enchanting Mekong and Siem Reap with Emerald Cruises
New ReleaseTour + River Cruise
 (7)

11 Days Ho Chi Minh City to Siem Reap
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to May 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$5,938
Balcony
$6,996
Suite
$9,196
From (Per Person)
A$5,938
Save 669
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
Tour + River Cruise
 (7)

21 Days Hanoi to Ho Chi Minh City
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
River View
$9,718
Balcony
$10,610
Suite
$12,786
From (Per Person)
A$9,718
Save 1,698
Per Person
View Trip
16 Day Wonders of Indochina and the Mekong with Emerald Cruises
Tour + River Cruise
 (7)

16 Days Ho Chi Minh City to Bangkok
Operator: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia, Laos, Thailand
Exclusive Savings
River View
$9,779
Balcony
$10,671
Suite
$12,847
From (Per Person)
A$9,779
Save 1,687
Per Person
View Trip
Results: 1-29 of 59

No trips found. Try adjusting the search filters.




River Cruises found! Scroll up to view.

Asia River Cruises

Asia River Cruises India (Ganges) River Cruises Mekong River Cruises Yangtze River Cruises

Countries

Cambodia Thailand Vietnam

Cities

River Cruises from Hanoi River Cruises from Ho Chi Minh City River Cruises from Siem Reap

Routes

River Cruises from Hanoi to Siem Reap River Cruises from Hanoi to Ho Chi Minh City River Cruises from Ho Chi Minh City to Siem Reap River Cruises from Siem Reap to Ho Chi Minh City
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations