Main River Cruises Starting In May 2026

If you're looking at joining a river cruise along the Main river in May 2026, we have 49 unique river cruises with 1,041 departures from the world's leading river cruise lines departing in May.
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Departures (May 2026)
Duration
8 Days
37 Days
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Price
$1,700pp
$44,920pp
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49 River Cruises (1,041 River Cruise Departures)
River Cruise
 (1)

9 Days Basel to Nuremberg
Cruise Line: Avalon River Cruises
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$3,503
Balcony
$5,477
Suite
$7,562
From
US$4,871
Save 1,384
Per Person
View Trip
River Cruise
 (1)

11 Days Basel to Munich
Cruise Line: Avalon River Cruises
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Exclusive Savings
Inside
-
River View
$4,347
Balcony
$6,321
Suite
$8,406
From
US$5,715
Save 1,419
Per Person
View Trip
New ReleaseRiver Cruise

11 Days Basel to Nuremberg
Cruise Line: Viking River Cruises
Departures: Apr 2026 to Nov 2027
Rivers: Rhine, Main
Visit: Switzerland, France, Germany
Multiple Deals Available
Inside
-
River View
$2,939
Balcony
$3,527
Suite
$4,899
From
US$2,939
Save 576
Per Person
View Trip
New ReleaseRiver Cruise

8 Days Amsterdam to Nuremberg
Cruise Line: Amadeus River Cruises
Departures: May 2026 to May 2026
Rivers: Rhine, Main
Visit: Holland, Germany
Exclusive Savings
Inside
-
River View
$2,680
Balcony
$3,561
Suite
$4,928
From
US$2,680
Save 150
Per Person
View Trip
New ReleaseRiver Cruise

11 Days Nuremberg to Basel
Cruise Line: Viking River Cruises
Departures: Apr 2026 to Nov 2027
Rivers: Main, Rhine
Visit: Germany, France, Switzerland
Multiple Deals Available
Inside
-
River View
$2,939
Balcony
$3,527
Suite
$4,899
From
US$2,939
Save 1,080
Per Person
View Trip
New ReleaseRiver Cruise

14 Days Paris to Prague
Operated By: Tauck
Departures: May 2026 to Oct 2026
Rivers: Moselle, Main
Visit: France, Luxembourg, Germany, Czech Republic
Complimentary Hotel Night
From
US$10,790
Per Person
View Trip
River Cruise
 (25)

15 Days Amsterdam to Budapest
Cruise Line: Viking River Cruises
Departures: Oct 2025 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Multiple Deals Available
Inside
-
River View
$4,899
Balcony
$5,879
Suite
$9,799
From
US$4,899
Save 1,986
Per Person
View Trip
River Cruise
 (80)

15 Days Amsterdam to Budapest
Cruise Line: Avalon River Cruises
Departures: Oct 2025 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Fly Free
Exclusive Savings
Inside
-
River View
$5,207
Balcony
$7,798
Suite
$11,542
From
US$5,207
Save 2,696
Per Person
View Trip
River Cruise
 (61)

15 or 16 Days Budapest to Amsterdam
Cruise Line: Avalon River Cruises
Departures: Oct 2025 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Fly Free
Exclusive Savings
Inside
-
River View
$6,029
Balcony
$8,620
Suite
$12,364
From
US$6,029
Save 1,732
Per Person
View Trip
River Cruise
 (14)

15 Days Budapest to Amsterdam
Cruise Line: Viking River Cruises
Departures: Mar 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$4,899
Balcony
$5,879
Suite
$9,799
From
US$4,899
Save 2,770
Per Person
View Trip
River Cruise
 (11)

15 Days Amsterdam to Budapest
Cruise Line: Scenic
Departures: Nov 2025 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Czech Republic, Slovakia, Hungary
Multiple Deals Available
Inside
-
River View
$7,050
Balcony
$9,378
Suite
$14,180
From
US$7,050
Save 16,658
Per Person
View Trip
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Emerald Cruises
Departures: Oct 2025 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary
Fly Free Economy
Early Payment Discount
Exclusive Savings
Inside
-
River View
$4,916
Balcony
$6,420
Suite
$11,173
From
US$4,916
Save 11,148
Per Person
View Trip
River Cruise
 (5)

15 Days Amsterdam to Budapest
Cruise Line: Uniworld River Cruises
Departures: Oct 2025 to Oct 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary
Exclusive Savings
Inside
-
River View
$6,858
Balcony
$8,682
Suite
$11,921
From
US$6,858
Save 685
Per Person
View Trip
River Cruise
 (5)

15 Days Budapest to Amsterdam
Cruise Line: Scenic
Departures: Oct 2025 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Czech Republic, Germany, Holland
Multiple Deals Available
Inside
-
River View
$6,808
Balcony
$9,378
Suite
$13,210
From
US$6,808
Save 12,890
Per Person
View Trip
River Cruise
 (5)

24 Days Bucharest to Amsterdam
Cruise Line: Uniworld River Cruises
Departures: May 2026 to Aug 2026
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Exclusive Savings
Inside
-
River View
$11,778
Balcony
$15,676
Suite
$20,457
From
US$11,778
Save 1,821
Per Person
View Trip
River Cruise
 (3)

23 Days Bucharest to Amsterdam
Cruise Line: Viking River Cruises
Departures: Apr 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Romania, Bulgaria, Serbia, Croatia (+4 more), Hungary, Austria, Germany, Holland
Flights Included
Exclusive Savings
Inside
-
River View
$8,819
Balcony
$11,024
Suite
$20,971
From
US$8,819
Save 3,328
Per Person
View Trip
New ReleaseRiver Cruise
 (3)

23 Days Oltenita to Amsterdam
Cruise Line: Avalon River Cruises
Departure: 08 May 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Exclusive Savings
Inside
-
River View
$12,532
Balcony
-
Suite
-
From
US$12,532
Save 492
Per Person
View Trip
River Cruise
 (2)

15 Days Budapest to Amsterdam
Cruise Line: Emerald Cruises
Departures: Feb 2026 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Fly Free Economy
Exclusive Savings
Inside
-
River View
$4,916
Balcony
$6,711
Suite
$11,173
From
US$4,916
Save 10,066
Per Person
View Trip
River Cruise
 (1)

23 Days Amsterdam to Bucharest
Cruise Line: Viking River Cruises
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Hungary (+4 more), Croatia, Serbia, Bulgaria, Romania
Flights Included
Exclusive Savings
Inside
-
River View
$8,525
Balcony
$11,270
Suite
$21,069
From
US$8,525
Save 2,848
Per Person
View Trip
River Cruise
 (1)

21 Days Paris to Prague
Cruise Line: Scenic
Departures: May 2026 to Sep 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Hungary, Slovakia, Czech Republic
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$11,376
Balcony
$14,335
Suite
$17,827
From
US$11,376
Save 16,758
Per Person
View Trip
New ReleaseRiver Cruise
 (1)

19 Days Zagreb to Amsterdam
Cruise Line: Scenic
Departures: May 2026 to Sep 2027
Rivers: Danube, Main, Rhine
Visit: Croatia, Slovenia, Hungary, Slovakia (+4 more), Austria, Czech Republic, Germany, Holland
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$9,824
Balcony
$12,783
Suite
$16,275
From
US$9,824
Save 9,365
Per Person
View Trip
River Cruise
 (4)

18 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Departures: Apr 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Fly Free Economy
Exclusive Savings
Inside
-
River View
$6,555
Balcony
$8,592
Suite
$13,054
From
US$7,065
Save 9,571
Per Person
View Trip
River Cruise
 (5)

21 Days Paris to Prague
Cruise Line: Emerald Cruises
Departures: May 2026 to Oct 2027
Rivers: Rhine, Main, Danube
Visit: France, Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Fly Free Economy
Exclusive Savings
Inside
-
River View
$7,845
Balcony
$9,950
Suite
$14,412
From
US$7,845
Save 11,201
Per Person
View Trip
New ReleaseRiver Cruise
 (3)

18 Days Budapest to Brussels
Cruise Line: Emerald Cruises
Departures: Apr 2026 to Oct 2027
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland, Belgium
Fly Free Economy
Exclusive Savings
Inside
-
River View
$7,108
Balcony
$9,145
Suite
$13,607
From
US$7,322
Save 10,094
Per Person
View Trip
River Cruise

34 Days Dublin to Budapest
Cruise Line: Scenic
Departures: May 2026 to Sep 2026
Rivers: Rhine, Main, Danube
Visit: Ireland, Northern Ireland, Scotland, England (+6 more), Holland, Germany, Czech Republic, Austria, Slovakia, Hungary
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
$18,898
Balcony
$21,711
Suite
$25,300
From
US$18,898
Save 9,653
Per Person
View Trip
River Cruise
 (5)

18 Days Amsterdam to Prague
Cruise Line: Emerald Cruises
Departures: May 2026 to Nov 2027
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia, Hungary, Czech Republic
Fly Free Economy
Exclusive Savings
Inside
-
River View
$6,555
Balcony
$8,592
Suite
$13,054
From
US$6,555
Save 11,168
Per Person
View Trip
River Cruise
 (5)

23 Days Amsterdam to Bucharest
Cruise Line: Emerald Cruises
Departures: May 2026 to Aug 2026
Rivers: Rhine, Main, Danube
Visit: Holland, Germany, Austria, Slovakia (+5 more), Hungary, Croatia, Serbia, Romania, Bulgaria
Fly Free Economy
Exclusive Savings
Inside
-
River View
$11,969
Balcony
-
Suite
-
From
US$11,969
Save 12,667
Per Person
View Trip
River Cruise
 (2)

25 Days Prague to Amsterdam
Cruise Line: Emerald Cruises
Departures: May 2026 to Oct 2026
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Germany, Poland, Hungary, Slovakia, Austria, Holland
Fly Free Economy
Exclusive Savings
Inside
-
River View
$9,393
Balcony
$11,430
Suite
$15,892
From
US$9,393
Save 8,525
Per Person
View Trip
River Cruise

15 Days Budapest to Amsterdam
Operated By: Tauck
Departures: Jun 2026 to Sep 2026
Rivers: Danube, Main, Rhine
Visit: Hungary, Slovakia, Austria, Germany, Holland
Complimentary Hotel Night
From
US$8,390
Per Person
View Trip
River Cruise

18 Days Prague to Amsterdam
Cruise Line: Scenic
Departures: Nov 2025 to Nov 2027
Rivers: Danube, Main, Rhine
Visit: Czech Republic, Hungary, Slovakia, Austria, Germany, Holland
Multiple Deals Available
Inside
-
River View
$7,593
Balcony
$10,552
Suite
$13,937
From
US$7,593
Save 12,913
Per Person
View Trip
Results: 1-30 of 49

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